Biological therapy in the reduction of cardiovascular risk in patients with psoriasis by Andrés Tirado-Sánchez

“…Psoriasis is a chronic inflammatory disease that primarily affects the skin, and its complications include a predisposition to atherosclerosis and cardiovascular disease (CVD), with this risk related to the severity of psoriasis. …”
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Differing Pattern of Ambulatory Blood Pressure in Very Elderly Men Expresses Dynamics in Atherosclerotic Load in the Senescence by Arkadiusz Siennicki-Lantz, Sölve Elmståhl

“…Higher ABPM reflects instead an increasing CBP and aggravating atherosclerosis during the preceding decade in that part of the cohort with previously favorable risk factor status.…”
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Overweight: atherogenesis risk marker in children between 8 and 9 years by Beatriz Sabina Roméu, Margarita Rosa Romeu Escobar, Juan José Apolinaire Pennini

“…<strong>Background:</strong> Many significant health problems hold the attention of pediatricians, and even when there is an increased interest on premature atherosclerosis risk factors, it is still a field to be studied. …”
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Cardiac function and quality of life improvement with fasudil hydrochloride in patients with diabetes post-PCI: a randomized controlled trial by Xuejia Yang, Qian Li, Yaning Liu, Ran Chen, Yanjing Liu, Chenghui Sun, Licha Kong, Qiuli Dong

“…Conclusions Fasudil hydrochloride effectively targets endothelial dysfunction and atherosclerosis, contributing to better cardiac performance and metabolic regulation. …”
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Therapeutic Implications of PPARγ in Cardiovascular Diseases by Hiroshi Hasegawa, Hiroyuki Takano, Issei Komuro

“…Many studies suggest that PPARγ ligands not only ameliorate insulin sensitivity, but also have pleiotropic effects on the pathophysiology of atherosclerosis, cardiac hypertrophy, ischemic heart, and myocarditis.…”
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MPNs as Inflammatory Diseases: The Evidence, Consequences, and Perspectives by Hans Carl Hasselbalch, Mads Emil Bjørn

“…In addition, chronic inflammation has been suggested to contribute to the development of premature atherosclerosis and may drive the development of other cancers in MPNs, both nonhematologic and hematologic. …”
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Lentiviral-Mediated shRNA Silencing of PDE4D Gene Inhibits Platelet-Derived Growth Factor-Induced Proliferation and Migration of Rat Aortic Smooth Muscle Cells by Lin Liu, Xiaowei Xu, Jiejie Li, Xia Li, Wenli Sheng

“…Proliferation and migration of vascular smooth muscle cells (VSMCs) play a critical role in the pathogenesis of atherosclerosis. In this study, infection of VSMCs with lentivrius particles carrying shRNA direct against PDE4D significantly inhibited platelet-derived growth factor-induced VSMC proliferation and migration, and the inhibitory effects were not associated with global intracellular cAMP level. …”
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Candidates for Bariatric Surgery: Morbidly Obese Patients with Pulmonary Dysfunction by Yu-Feng Wei, Huey-Dong Wu

“…Effective weight loss after bariatric surgery may improve cardiovascular disease risk factors, including diabetes, hypertension, dyslipidemia, atherosclerosis, inflammation, chronic kidney disease, obstructive sleep apnea, and obesity hypoventilation syndrome. …”
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Galectin-3: A Novel Marker for the Prediction of Stroke Incidence and Clinical Prognosis by Ahmed Sayed, Malak Munir, Mohamed S. Attia, Badrah S. Alghamdi, Ghulam Md Ashraf, Eshak I. Bahbah, Mohamed Elfil

“…Among these proteins, a few studies investigated mainly the roles played by galectin-1 (Gal-1) and galectin-3 (Gal-3) in the molecular mechanisms of atherosclerosis and in brain tissue remodeling after a stroke event. …”
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Association of Inflammatory Markers/Cytokines with Cardiovascular Risk Manifestation in Patients with Endometriosis by Uzma Rafi, Shaaf Ahmad, Syeda Shazia Bokhari, Muhammad Amir Iqbal, Amna Zia, Muhammad Amjad Khan, Nabila Roohi

“…The results of the study revealed that the patients with endometriosis demonstrate a hypercoagulable status due to inflammation, which initiates atherosclerosis and associated complications. Hence, endometriosis can cause a risk of cardiovascular disorders in these patients.…”
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Higher-Order Chromatin Regulation of Inflammatory Gene Expression by Jin-Wen Xu, Shuang Ling, Jun Liu

“…Whether it is caused by viruses and bacteria infection, or low-grade chronic inflammation of atherosclerosis and cellular senescence, the transcription factor (TF) NF-κB plays a central role in the inducible expression of inflammatory genes. …”
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Cross-Talk between Gut Microbiota and Heart via the Routes of Metabolite and Immunity by Jin Bu, Zhaohui Wang

“…Dysbiosis, characterized by changes in the gut microbiota in CVD, has been reported in cardiovascular pathologies, such as atherosclerosis, hypertension, and heart failure. Conversely, gut microbiota-derived metabolites, such as trimethylamine/trimethylamine N-oxide (TMA/TMAO), can impact host physiology. …”
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Homocysteine and Hypertension in Diabetes: Does PPARγ Have a Regulatory Role? by Utpal Sen, Suresh C. Tyagi

“…Dysfunction of macro- and microvessels is a major cause of morbidity and mortality in patients with cardio-renovascular diseases such as atherosclerosis, hypertension, and diabetes. Renal failure and impairment of renal function due to vasoconstriction of the glomerular arteriole in diabetic nephropathy leads to renal volume retention and increase in plasma homocysteine level. …”
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Atherosclerotic Risk Factors in Children with Celiac Disease by Anna Rybak, Aldona Wierzbicka, Piotr Socha, Anna Stolarczyk, Bożena Cukrowska, Łukasz Obrycki, Zbigniew Wawer, Roman Janas, Beata Oralewska, Anna Szaflarska-Popławska, Barbara Iwańczak, Elżbieta Cyrta-Jarocka, Urszula Grzybowska-Chlebowczyk, Wojciech Cichy, Grażyna Czaja-Bulsa, Jerzy Socha

“…Hereby, we present our study regarding the impact of treatment with GFD on the biochemical risk factors of atherosclerosis. Material and Methods. 277 patients with CD from 7 Polish clinics were enrolled in the study (210 children treated for at least 5 years and 67 children included in the study on the day of CD diagnosis and observed for 1 year on a GFD). …”
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Role of cardiac CT in the diagnostic evaluation and risk stratification of patients with myocardial infarction and non-obstructive coronary arteries (MINOCA): rationale and design... by Konstantinos Tsioufis, Haralambos Karvounis, George Giannakoulas, Theodoros Karamitsos, Ronny R Buechel, Konstantinos Kouskouras, Ioannis Vogiatzis, Konstantinos Toutouzas, Nathaniel R Smilowitz, Georgios P Rampidis, Polydoros Ν Kampaktsis, Athanasios Samaras, Georgios Benetos, Andreas Α Giannopoulos, Alexandros Kallifatidis, Antonios Samaras, Stavros Hadjimiltiades, Antonios Ziakas, Catherine Gebhard, Panagiotis Prassopoulos, Harmony Reynolds

“…The primary endpoints are quantification of extent and severity of coronary atherosclerosis, description of high-risk plaque features and attenuation profiling of pericoronary fat tissue around all three major epicardial coronary arteries in relation to CMR. …”
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Crosstalk between the Gut and Brain in Ischemic Stroke: Mechanistic Insights and Therapeutic Options by Wenjing Huang, Luwen Zhu, Wenjing Song, Mei Zhang, Lili Teng, Minmin Wu

“…This review summarizes the role of MGBA signaling in the development of stroke risk factors such as aging, hypertension, obesity, diabetes, and atherosclerosis, as well as changes in the microbiota in experimental or clinical populations. …”
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Insulin Resistance and Endothelial Dysfunction Constitute a Common Therapeutic Target in Cardiometabolic Disorders by A. Janus, E. Szahidewicz-Krupska, G. Mazur, A. Doroszko

“…Insulin resistance and other risk factors for atherosclerosis, such as hypertension and hypercholesterolemia, promote endothelial dysfunction and lead to development of metabolic syndrome which constitutes an introduction to cardiovascular disease. …”
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Serum Amyloid A as a Marker of Persistent Inflammation and an Indicator of Cardiovascular and Renal Involvement in Patients with Rheumatoid Arthritis by Bożena Targońska-Stępniak, Maria Majdan

“…Serum amyloid A (SAA) is an acute-phase protein, involved in pathogenesis of atherosclerosis. The aim of the study was to assess serum concentration of SAA in RA patients, with reference to other inflammatory parameters and markers of extra-articular involvement. …”
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Chronic coronary occlusions in patients after coronary artery bypass grafting. Morphological features and a review of possible interventions by S.М. Furkalo

“…Although precise mechanism of atherosclerosis in these patients unknown, several clinical studies reported that atherosclerotic progression occurs more rapidly in grafted arteries than in non-grafted arteries. …”
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Advantages and disadvantages of coronary drug-eluting stent: a 23-year journey of randomized clinical trials by Alfredo E. Rodriguez, Juan Mieres, Juan M. Rokos

“…However, that should be counterbalanced by the high incidence of spontaneous MI mainly due to early neo-atherosclerosis with DES. The finding of a high incidence of non-cardiac death observed in DES trials compared to coronary artery bypass grafting and optimal medical treatment is disturbing, and the reasons are unknown. …”
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