Showing 281 - 300 results of 622 for search '"atherosclerosis"', query time: 0.05s Refine Results
  1. 281

    Epidemiological and Pathogenic Relationship between Sleep Apnea and Ischemic Heart Disease by Carlos Carpio, Rodolfo Álvarez-Sala, Francisco García-Río

    Published 2013-01-01
    “…The pathophysiology of coronary artery disease in obstructive sleep apnea patients probably includes the activation of multiple mechanisms, as the sympathetic activity, endothelial dysfunction, atherosclerosis, and systemic hypertension. Moreover, chronic intermittent hypoxia and oxidative stress have an important role in the pathogenesis of coronary disease and are also fundamental to the development of atherosclerosis and other comorbidities present in coronary artery diseases such as lipid metabolic disorders. …”
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  2. 282

    Low-Grade Systemic Inflammation Profile, Unrelated to Homocysteinemia, in Obese Children by Emanuel V. Economou, Ariadne V. Malamitsi-Puchner, Christos P. Pitsavos, Evangelia E. Kouskouni, Ioanna Magaziotou-Elefsinioti, George Creatsas

    Published 2005-01-01
    “…Thus, in POC, positively interrelated to each other, elevated CRP and unaltered SAA levels reveal a unique profile of the CLGSI, not explaining homocysteinemia-induced risk for future atherosclerosis.…”
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  3. 283
  4. 284

    CD137 Signaling Promotes Endothelial Apoptosis by Inhibiting Nrf2 Pathway, and Upregulating NF-κB Pathway by Tianxin Geng, Yang Yan, Yue Zhang, Liangjie Xu, Guangyao Zang, Jin Chuan Yan

    Published 2020-01-01
    “…Endothelial dysfunction and apoptosis resulting from oxidative stress can lead to the development of atherosclerosis. Our group has previously showed that CD137 signaling contributes to the progression of atherosclerosis and the vulnerability of plaques. …”
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  5. 285

    COX-2 Gene Promoter Polymorphism and Coronary Artery Disease in Middle-Aged Men: The Helsinki Sudden Death Study by Kati H. Huuskonen, Tarja A. Kunnas, Minna M. Tanner, Jussi Mikkelsson, Erkki Ilveskoski, Pekka J. Karhunen, Seppo T. Nikkari

    Published 2008-01-01
    “…Cyclooxygenase (COX) catalyzes formation of prostaglandins that contribute to the inflammation in atherosclerosis. Our objective was to study whether the functional C variant of the −765G→C polymorphism in the human COX-2 gene associates with the severity of coronary atherosclerosis measured at the coronary artery level. …”
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  6. 286

    The Role of Insulin Receptor Isoforms in Diabetes and Its Metabolic and Vascular Complications by O. Escribano, N. Beneit, C. Rubio-Longás, A. R. López-Pastor, A. Gómez-Hernández

    Published 2017-01-01
    “…This review discussed specifically the role of IR isoforms as well as IGF-IR in diabetes and its associated complications as obesity and atherosclerosis. Future research with new IR modulators might be considered as possible targets to improve the treatment of diabetes and its associated complications.…”
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  7. 287

    Effect of Adiponectin Variant on Lipid Profile and Plasma Adiponectin Levels: A Multicenter Systematic Review and Meta-Analysis by Guiqing Wang, Yufeng Wang, Zhi Luo

    Published 2022-01-01
    “…Children with the rs266729 variant had a high risk to develop dyslipidemia, atherosclerosis, and even early onset of CAD in the future. …”
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  8. 288

    Advancing Insights into Large-Artery Stiffening in Humans Through the Application of Multi-omics by Marie-Joe Dib

    Published 2024-07-01
    “…Importantly, LAS is pathologically different from atherosclerosis as it rather occurs primarily from changes in the medial aortic layer, and can manifest itself in the absence of plaque formation. …”
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  9. 289

    Ataxin-10 Inhibits TNF-α-Induced Endothelial Inflammation via Suppressing Interferon Regulatory Factor-1 by Yong Li, Qi Zhang, Na Li, Liting Ding, Jinping Yi, Yue Xiao, Shibiao Chen, Xuan Huang

    Published 2021-01-01
    “…Endothelial inflammation is a crucial event in the initiation of atherosclerosis. Here, we identify Ataxin-10 protein as a novel negative modulator of endothelial activation by suppressing IRF-1 transcription activity. …”
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    Article
  10. 290

    Rituximab Efficacy during a Refractory Polyarteritis Nodosa Flare by Emmanuel Ribeiro, Thomas Cressend, Pierre Duffau, Marieke Grenouillet-Delacre, Marie Rouanet-Larivière, Anne Vital, Maïté Longy-Boursier, Patrick Mercié

    Published 2009-01-01
    “…Systemic vasculitis relapses are followed to accelerated atherosclerosis: severe ischemic lesions led to amputation of lower limbs. …”
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  11. 291

    Paraoxonase 2 Induces a Phenotypic Switch in Macrophage Polarization Favoring an M2 Anti-Inflammatory State by Marie Koren-Gluzer, Mira Rosenblat, Tony Hayek

    Published 2015-01-01
    “…Inflammatory processes are involved in atherosclerosis development. Macrophages play a major role in the early atherogenesis, and they are present in the atherosclerotic lesion in two phenotypes: proinflammatory (M1) or anti-inflammatory (M2). …”
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  12. 292

    Relation of Asymmetric Dimethylarginine Levels to Macrovascular Disease and Inflammation Markers in Type 2 Diabetic Patients by Mustafa Celik, Serkan Cerrah, Mahmut Arabul, Aysen Akalin

    Published 2014-01-01
    “…We recruited 50 type 2 diabetic patients with atherosclerosis, 50 type 2 diabetic patients without atherosclerosis, and 31 healthy control patients into our study. …”
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  13. 293

    Impact of Diabetes on Cardiovascular Disease: An Update by Alessandra Saldanha de Mattos Matheus, Lucianne Righeti Monteiro Tannus, Roberta Arnoldi Cobas, Catia C. Sousa Palma, Carlos Antonio Negrato, Marilia de Brito Gomes

    Published 2013-01-01
    “…The proposed mechanisms that can link accelerated atherosclerosis and increased cardiovascular risk in this population are poorly understood. …”
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  14. 294

    Role of Rutin on Nitric Oxide Synthesis in Human Umbilical Vein Endothelial Cells by Azizah Ugusman, Zaiton Zakaria, Kien Hui Chua, Nor Anita Megat Mohd Nordin, Zaleha Abdullah Mahdy

    Published 2014-01-01
    “…Oxidative stress plays an important role in the pathogenesis of various cardiovascular diseases, including atherosclerosis. Decreased availability of endothelial NO promotes the progression of endothelial dysfunction and atherosclerosis. …”
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  15. 295

    Does structural compromise of the aorta in patients with aortic pathologies predict increased spinal and vascular complications and reoperations in patients undergoing anterior app... by Neil V. Shah, Pelin Çeliker, Cirous Sadeghi, Rachel Baum, Juhayer S. Alam, Chibuokem Ikwuazom, Peter L. Zhou, Benjamin Krasnyanskiy, David Kim, Rohan Desai, Sandeep Bains, Jeffrey M. Schwartz, Bassel G. Diebo, Carl B. Paulino

    Published 2024-12-01
    “…Previous reports have detailed vascular injuries during exposure/approach; however, it is not well-documented whether structural aortic pathology, such as aneurysm, dissection, atherosclerosis, aortitis, or aortic tumors, impacts postoperative outcomes following anterior approach to the spine for spinal fusion. …”
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  16. 296

    Downregulation of CD4+LAP+ and CD4+CD25+ Regulatory T Cells in Acute Coronary Syndromes by Ying-zhong Lin, Shan-he Lu, Zheng-de Lu, Ying Huang, Ying Shi, Ling Liu, Xiao-yan Wang, Qing-wei Ji

    Published 2013-01-01
    “…CD4+LAP+ Treg cells are a novel subset of Tregs that have been found to ameliorate atherosclerosis in ApoE-/- mice, and these cells also exist in humans. …”
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  17. 297

    Atherogenic Risk Factors in Medical Students by Airam Navarro Palacios, Miguel Ángel Serra Valdés, Rafael Comas Valdespino, Girelda Cordero López, Alain Landrian Davis, Adrian Landrian Davis

    Published 2020-12-01
    “…<strong>Background:</strong> atherosclerosis is a multifactorial origin disease. The study and approach of its modifiable risk factors and action on these factors can positively change the health situation. …”
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  18. 298

    Pengaruh Lama Pemberian Diet Tinggi Kolesterol terhadap Kadar LDL dan TGF-Β Serum Tikus Putih (Rattus novergicus) strain Wistar by Biomechy Oktomalioputri, Eryati Darwin, Eva Decroli

    Published 2016-01-01
    “…</em></p><p><strong>Kata kunci:</strong> diet tinggi kolesterol, LDL<em>,</em> TGF-β</p><p><strong><em> </em></strong></p><p><strong><em>Abstract</em></strong></p><p><em>High-cholesterol diet will increase </em><em>Low Density Lipoprotein</em><em> </em><em>(LDL) levels which impact to atherosclerosis. </em><em>Transforming Growth Factor β (</em><em>TGF-β) play a role in atherosclerosis process. …”
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  19. 299

    The Level of hs-CRP in Coronary Artery Ectasia and Its Response to Statin and Angiotensin-Converting Enzyme Inhibitor Treatment by Yilmaz Ozbay, Mehmet Akbulut, Mehmet Balin, Hidayet Kayancicek, Adil Baydas, Hasan Korkmaz

    Published 2007-01-01
    “…The anti-inflammatory effects of statins and the effect of angiotensin-converting enzyme (ACE) inhibitors on endothelial dysfunction are well established in atherosclerosis. The aim of the present study was to investigate CRP level and its response to statin and ACE inhibitor treatment in CAE. …”
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  20. 300

    Identification of key genes associated with oxidative stress in ischemic stroke via bioinformatics integrated analysis by Gaiyan Li, Yu Cheng, Shanshan Ding, Qianyun Zheng, Lanqiong Kuang, Ying Zhang, Ying Zhou

    Published 2025-01-01
    “…Although the formation of atherosclerosis, which is closely related to oxidative stress (OS), is associated with stroke-related deaths. …”
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