Asymmetric synthesis of stereogenic-at-iridium(III) complexes through Pd-catalyzed kinetic resolution by Yun-Peng Chu, Xue-Lin Yue, De-Hai Liu, Chuanyong Wang, Jiajia Ma

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Flow chemistry-enabled asymmetric synthesis of cyproterone acetate in a chemo-biocatalytic approach by Yajiao Zhang, Minjie Liu, Xianjing Zheng, Liang Gao, Li Wan, Dang Cheng, Fener Chen

“…Herein, we report the 10-step chemo-biocatalytic continuous flow asymmetric synthesis of cyproterone acetate (4) in which 10 transformations are combined into a telescoped flow linear sequence from commercially available 4-androstene-3, 17-dione (11). …”
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The need for Open Labs for fostering interdisciplinarities in Modern Chemistry. Biocatalysis: a necessary tool for synthetic chemists by Martin, Juliette

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Enantioselective Synthesis of Antiepileptic Drug: (-)-Levetiracetam—Synthetic Applications of the Versatile New Chiral N-Sulfinimine by K. Chandra Babu, R. Buchi Reddy, E. Naresh, K. Ram Mohan, G. Madhusudhan, K. Mukkanti

“…We report an asymmetric synthesis of (-)-Levetiracetam (1) in six steps starting from versatile new chiral N-sulfinimine (3). …”
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Iron-catalysed stereoselective NH transfer enables dynamic kinetic resolution of sulfoxides by Fang-Xu Fan, Hui Xu, Shi-Xiong Tang, Yanfeng Dang, Fei Wang

“…We report here an iron-catalysed stereoselective NH imidation of sulfoxide, which is integrated with photocatalytic racemisation of sulfoxide, enabling a dynamic kinetic resolution (DKR) strategy for direct and asymmetric synthesis of NH-sulfoximines. This approach is distinct from the existing methods by avoiding protecting group manipulations and/or the use of chiral substrates. …”
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Two decades of fluorine chemistry in Cergy by Pytkowicz, Julien, Chaume, Grégory, Lensen, Nathalie, Chelain, Evelyne, Brigaud, Thierry

“…We propose in this review an overview of our contributions to organofluorine chemistry in connection with biological applications and also asymmetric synthesis these past twenty years in Université de Cergy-Pontoise (now CY Cergy Paris Université).…”
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An unusual chiral-at-metal mechanism for BINOL-metal asymmetric catalysis by Zhenxing Li, Pengfei Chen, Zhigang Ni, Liuzhou Gao, Yue Zhao, Ranran Wang, Congqing Zhu, Guoqiang Wang, Shuhua Li

“…Abstract Chiral binaphthols (BINOL)-metal combinations serve as powerful catalysts in asymmetric synthesis. Their chiral induction mode, however, typically relies on multifarious non-covalent interactions between the substrate and the BINOL ligand. …”
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