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121
Characteristics of TSPO expression in marmoset EAE
Published 2025-01-01“…However, we also find increased astrocytic TSPO expression in chronic-appearing lesions with astrogliosis. …”
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122
Spinal Cord Pathology in Alpha-Synuclein Transgenic Mice
Published 2010-01-01“…In addition, these mice exhibit astrocytic cell death in the spinal cord, accompanied by extensive gliosis and microglial activation. …”
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123
Glioblastomas with Oligodendroglial Component – Common Origin of the Different Histological Parts and Genetic Subclassification
Published 2010-01-01“…Our objective was to genetically characterize the oligodendroglial and the astrocytic parts of GBMOs and correlate morphologic and genetic features with clinical data.…”
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124
Identifying the function of novel cross-species microRNAs from the excretory-secretory products of Angiostrongylus cantonensis fifth-stage larvae
Published 2025-02-01“…Next, we evaluated the effects of AcESPs-microRNAs in A. cantonensis ESPs treated astrocytes. Results: First, we established the secreted microRNA dataset, and then comprehensively verified the characteristics. …”
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125
Glial Cells of the Central Nervous System: A Potential Target in Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Published 2023-01-01“…Only microglia and astrocytes have been studied in the animal model of CP/CPPS. …”
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126
Plasticity of Neuron-Glial Transmission: Equipping Glia for Long-Term Integration of Network Activity
Published 2015-01-01“…In recent years, glial cells (most notably astrocytes) have been recognized as active participants in the modulation of synaptic transmission and synaptic plasticity, implicating these electrically nonexcitable cells in information processing in the brain. …”
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127
Differential Cannabinoid Receptor Expression during Reactive Gliosis: a Possible Implication for a Nonpsychotropic Neuroprotection
Published 2009-01-01“…Activated microglia and astrocytes produce a large number of inflammatory and neurotoxic substances in various brain pathologies, above all during neurodegenerative disorders. …”
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128
Potential Role of JAK-STAT Signaling Pathway in the Neurogenic-to-Gliogenic Shift in Down Syndrome Brain
Published 2016-01-01“…DS brain is characterized by an increased number of astrocytes with reduced number of neurons. In mouse models for DS, the pool of neural progenitor cells commits to glia rather than neuronal cell fate in the DS brain. …”
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129
Augmentation of Tonic GABAA Inhibition in Absence Epilepsy: Therapeutic Value of Inverse Agonists at Extrasynaptic GABAA Receptors
Published 2011-01-01“…These results challenge the existing theory that typical absence seizures are underpinned by a widespread loss of GABAergic function in thalamocortical circuits and illustrate a vital role for astrocytes in the pathology of typical absence epilepsy. …”
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130
Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation
Published 2013-01-01“…Consequently, activated microglia and astrocytes release ATP and glutamate, affecting myelinization, neuronal development, and survival. …”
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131
Cerebral hypoperfusion reduces tau accumulation
Published 2025-01-01“…An animal model demonstrates that chronic cerebral hypoperfusion reduces tau pathology, which was observed in not only neurons but also astrocytes, microglia, and oligodendrocytes. Furthermore, we found that astrocytes and microglia were activated in response to tau pathology and chronic cerebral hypoperfusion. …”
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132
Cell-specific transcriptional signatures of vascular cells in Alzheimer’s disease: perspectives, pathways, and therapeutic directions
Published 2025-01-01“…The neurovascular unit (NVU) is composed of various cell types, including endothelial cells, mural cells (pericytes, smooth muscle cells), fibroblast neurons, microglia, and astrocytes. Dysregulated transcriptional pathways in AD involve multiple pathways, notably immune responses, and angiogenesis common to both endothelial and mural cells. …”
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133
Levo-Tetrahydropalmatine Attenuates Bone Cancer Pain by Inhibiting Microglial Cells Activation
Published 2015-01-01“…However, L-THP failed to affect TCI-induced astrocytes activation and IL-1β increase. Conclusion. …”
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134
Pleomorphic xanthoastrocytoma, case series and review of literature
Published 2025-02-01“…Abstract Background Pleomorphic xanthoastrocytoma is a rare circumscribed astrocytic glial neoplasm that represents less than 1% of astrocytic tumors. …”
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135
Role of Scavenger Receptors in Glia-Mediated Neuroinflammatory Response Associated with Alzheimer’s Disease
Published 2013-01-01“…It is widely accepted that cells serving immune functions in the brain, namely, microglia and astrocytes, are important mediators of pathological phenomena observed in Alzheimer’s disease. …”
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136
Interleukin 10 Plays an Important Role in Neonatal Rats with Hypoxic-Ischemia Associated with B-Cell Lymphoma 2 and Endoplasmic Reticulum Protein 29
Published 2021-01-01“…The results demonstrated that the IL-10 expression was markedly increased after HI and IL-10 were colocalized with neurons and astrocytes which were badly injured by HI insult. In addition, Bcl-2 and ERp29 were remarkably decreased following IL-10 mRNA interference compared with the NC group. …”
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137
Hippocampal Neurogenesis and the Brain Repair Response to Brief Stereotaxic Insertion of a Microneedle
Published 2013-01-01“…Brief stereotaxic insertion and removal of a microneedle into the right hippocampus resulted in (a) significantly increased expression of granulocyte-colony stimulating factor (G-CSF), the chemokine MIP-1a, and the proinflammatory cytokine IL12p40; (b) pronounced activation of microglia and astrocytes; and (c) increase in hippocampal neurogenesis. …”
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138
Distinct expression profile reveals glia involvement in the trigeminal system attributing to post-traumatic headache
Published 2024-11-01“…In situ assays also revealed that gliosis of satellite glial cells in the TG and astrocytes in the Sp5C were prominent days after injury. …”
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139
Bone Morphogenetic Protein 4 Signalling in Neural Stem and Progenitor Cells during Development and after Injury
Published 2016-01-01“…Here we review recent studies on BMP4 signalling in the generation of neurons, astrocytes, and oligodendroglial cells in the CNS. We also discuss putative mechanisms that BMP4 may utilise to influence glial cell development following CNS injury and highlight some questions for further research.…”
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140
Development and in vitro evaluation of biomimetic injectable hydrogels from decellularized human nerves for central nervous system regeneration
Published 2025-04-01“…Compared to LPS-activated cells on tissue culture plates (TCP), astrocytes within iHPN maintained a quiescent state, as evidenced by reduced GFAP expression and IL-1β secretion. …”
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