Supplementation with Branched-Chain Amino Acids Induces Unexpected Deleterious Effects on Astrocyte Survival and Intracellular Metabolism with or without Hyperammonemia: A Preliminary In Vitro Study by Ting Wang, Kazuyuki Suzuki, Toshimi Chiba, Keisuke Kakisaka, Yasuhiro Takikawa

“…Furthermore, BCAA treatment was found to cause decreased levels of Glut-1 and phosphorylated GSK-3β and mTOR in astrocytes. Conclusions. Although further investigations of the effect of BCAA on human astrocytes with hyperammonemia are needed, our work demonstrates that BCAA supplementation has direct negative effects on astrocyte survival and intracellular metabolism.…”
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The Role of Neuroglia in the Development and Progression of Schizophrenia by Neha S. Rawani, Allen W. Chan, Kathryn G. Todd, Glen B. Baker, Serdar M. Dursun

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The Rise of Pluripotent Stem Cell-Derived Glia Models of Neuroinflammation by Srishti Kala, Andrew G. Strutz, Moriah E. Katt

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S-Equol, a Major Isoflavone from Soybean, Inhibits Nitric Oxide Production in Lipopolysaccharide-Stimulated Rat Astrocytes Partially via the GPR30-Mediated Pathway by Mitsuaki Moriyama, Ayano Hashimoto, Hideyo Satoh, Kenji Kawabe, Mizue Ogawa, Katsura Takano, Yoichi Nakamura

“…These findings suggest that attenuation of NO production by S-equol may mitigate LPS-induced neuroinflammation in astrocytes. S-Equol may exert a glioprotective effect, at least in part, via a nongenomic effect.…”
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Fumonisin B1 neurotoxicity: Preclinical evidence, biochemical mechanisms and therapeutic strategies by Blessing A. Obafemi, Isaac A. Adedara, Cássia Pereira Delgado, Olabisi T. Obafemi, Michael Aschner, Joao B.T. Rocha

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Hyperhomocysteinemia-induced VCID results in visual deficits, reduced neuroinflammation and vascular alterations in the retina by Erica M. Weekman, Colin B. Rogers, Tiffany L. Sudduth, Donna M. Wilcock

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Efficacy of human umbilical cord mesenchymal stem cell in the treatment of neuromyelitis optica spectrum disorders: an animal study by Chunran Xue, Haojun Yu, Xuzhong Pei, Xiaoying Yao, Jie Ding, Xiying Wang, Yi Chen, Yangtai Guan

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Neuroinflammation and iron metabolism after intracerebral hemorrhage: a glial cell perspective by Jia-Jun Ju, Li-Hua Hang, Li-Hua Hang

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From Homeostasis to Neuroinflammation: Insights into Cellular and Molecular Interactions and Network Dynamics by Ludmila Müller, Svetlana Di Benedetto, Viktor Müller

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Anti-inflammatory effects of moxifloxacin and levofloxacin on cadmium-activated human astrocytes: Inhibition of proinflammatory cytokine release, TLR4/STAT3, and ERK/NF-κB signaling pathway by Suttinee Phuagkhaopong, Jidapha Sukwattanasombat, Kran Suknuntha, Christopher Power, Piyanuch Wonganan, Pornpun Vivithanaporn

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Glial fibrillary acidic protein and S100b protein immunoreactivity in the hippocampus of weaning rats from dams treated with acrylamide during pregnancy by Karol Rycerz, Aleksandra E. Krawczyk, Jadwiga Jaworska-Adamu, Ewa Tomaszewska, Siemowit Muszyński, Piotr Dobrowolski, Marcin Arciszewski

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Modeling of Blood Flow Dynamics in Rat Somatosensory Cortex by Stéphanie Battini, Nicola Cantarutti, Christos Kotsalos, Yann Roussel, Alessandro Cattabiani, Alexis Arnaudon, Cyrille Favreau, Stefano Antonel, Henry Markram, Daniel Keller

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The current state of knowledge on the role of NKG2D ligands in multiple sclerosis and other autoimmune diseases by Aleksandra Pogoda-Wesołowska, Nina Sługocka, Agnieszka Synowiec, Klaudia Brodaczewska, Marcin Mejer-Zahorowski, Maciej Ziękiewicz, Wojciech Szypowski, Piotr Szymański, Adam Stępień

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The ABC transporter A7 modulates neuroinflammation via NLRP3 inflammasome in Alzheimer’s disease mice by Irene Santos-García, Pablo Bascuñana, Mirjam Brackhan, María Villa, Ivan Eiriz, Thomas Brüning, Jens Pahnke

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Evaluation of cannabinoid type 2 receptor expression and pyridine-based radiotracers in brains from a mouse model of Alzheimer’s disease by Vasil Kecheliev, Francesco Spinelli, Adrienne Herde, Achi Haider, Linjing Mu, Linjing Mu, Jan Klohs, Simon M. Ametamey, Ruiqing Ni, Ruiqing Ni

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Enhanced Interleukin 6 Trans-Signaling Modulates Disease Process in Amyotrophic Lateral Sclerosis Mouse Models by Carol Milligan, Dale O. Cowley, William Stewart, Alyson M. Curry, Elizabeth Forbes, Brian Rector, Annette Hastie, Liang Liu, Gregory A. Hawkins

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Acupoint catgut embedding alleviates experimental autoimmune encephalomyelitis by modulating neuroinflammation and potentially inhibiting glia activation through JNK and ERK pathwa... by Xiaofang Liu, Liansheng Yang, Zhumin Su, Xueying Ma, Yingying Liu, Lili Ma, Xiaomeng Ma, Mingxia Ma, Xiaoyun Liu, Kun Zhang, Kun Zhang, Xiaohong Chen

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The compound (E)-2-(3,4-dihydroxystyryl)-3-hydroxy-4H-pyran-4-one alleviates neuroinflammation and cognitive impairment in a mouse model of Alzheimer’s disease by Xueyan Liu, Wei Wu, Xuejuan Li, Chengyan Wang, Ke Chai, Fanru Yuan, Huijuan Zheng, Yuxing Yao, Chenlu Li, Zu-Cheng Ye, Daijun Zha

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Spatial transcriptomics combined with single-nucleus RNA sequencing reveals glial cell heterogeneity in the human spinal cord by Yali Chen, Yiyong Wei, Jin Liu, Tao Zhu, Cheng Zhou, Donghang Zhang

Subjects: “…astrocyte…”
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APOEε4 alters ApoE and Fabp7 in frontal cortex white matter in prodromal Alzheimer's disease by Marta Moreno-Rodriguez, Sylvia E. Perez, Michael Malek-Ahmadi, Elliott J. Mufson

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