Showing 161 - 180 results of 1,032 for search '"asthma"', query time: 0.06s Refine Results
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    Is platelet activating factor (PAF) an important mediator in bronchial asthma? by R. H. Gundel, H. O. Heuer, L. G. Letts

    Published 1992-01-01
    “…The development of selective PAF receptor antagonists may provide a novel approach to the treatment of human bronchial asthma. In preclinical animal models of human asthma, PAF receptor antagonists have been found to be efficacious in blocking antigen-induced changes in lung function. …”
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  4. 164
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    Cellular Mechanisms Underlying Eosinophilic and Neutrophilic Airway Inflammation in Asthma by Girolamo Pelaia, Alessandro Vatrella, Maria Teresa Busceti, Luca Gallelli, Cecilia Calabrese, Rosa Terracciano, Rosario Maselli

    Published 2015-01-01
    “…Eosinophilic inflammation can be associated with the whole spectrum of asthma severity, ranging from mild-to-moderate to severe uncontrolled disease, whereas neutrophilic inflammation occurs mostly in more severe asthma. …”
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    Direct Health Care Costs Associated with Asthma in British Columbia by Mohsen Sadatsafavi, Larry Lynd, Carlo Marra, Bruce Carleton, Wan C Tan, Sean Sullivan, J Mark FitzGerald

    Published 2010-01-01
    “…BACKGROUND: A better understanding of health care costs associated with asthma would enable the estimation of the economic burden of this increasingly common disease.…”
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  8. 168

    Efficacy of tezepelumab in patients with severe asthma and persistent airflow obstruction by Elliot Israel, Mario Castro, Christopher S. Ambrose, Jean-Pierre Llanos, Nestor A. Molfino, Nicole L. Martin, Sandhia S. Ponnarambil, Neil Martin

    Published 2024-11-01
    “…Background Persistent airflow obstruction (PAO) in patients with asthma can be difficult to treat. Tezepelumab blocks thymic stromal lymphopoietin, an epithelial cytokine implicated in asthma pathogenesis. …”
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    TNF-α Dysregulation in Asthma: Relationship to Ongoing Corticosteroid Therapy by Susan Waserman, Jerry Dolovich, Mary Conway, Jean S Marshall

    Published 2000-01-01
    “…BACKGROUND: Tumour necrosis factor-alpha (TNF-α) is a major proinflammatory cytokine that is thought to be important in the pathogenesis of asthma. However, alterations in systemic regulation of this cytokine in asthma have not been examined in the context of corticosteroid therapy.…”
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  11. 171

    Emerging Comorbidities in Adult Asthma: Risks, Clinical Associations, and Mechanisms by Hannu Kankaanranta, Paula Kauppi, Leena E. Tuomisto, Pinja Ilmarinen

    Published 2016-01-01
    “…Asthma is a heterogeneous disease with many phenotypes, and age at disease onset is an important factor in separating the phenotypes. …”
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  12. 172

    The Impact of Nationally Coordinated Pharmacy-Based Asthma Education Intervention by Shelley Anne Diamond, Kenneth Ross Chapman

    Published 2001-01-01
    “…OBJECTIVE: To assess the impact of a nationally coordinated pharmacy-based educational intervention on self-management behaviour and markers of asthma control in self-referred patients with asthma.…”
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    Asthma in Children and Adults: A Shared Biological and Molecular Basis by Paolo M Renzi

    Published 1995-01-01
    “…A comparison of the reported clinical presentation, physiological changes, histology and cellular biology of asthma in different age groups is presented with special emphasis on the abnormal immune response, cellular activation and lymphokine production. …”
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    Overreliance on Bronchodilators as a Risk Factor for Life-Threatening Asthma by Pierre Ernst, Brenda Hemmelgarn, Donald W Cockcroft, Samy Suissa

    Published 1995-01-01
    “…OBJECTIVE: To assess the potential impact on the risk of life-threatening asthma of current recommendations in pharmacotherapy, which emphasize the early use of steroids and the avoidance of beta-agonist overuse.…”
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  17. 177

    Combination of Fractional Exhaled Nitric Oxide (FeNO) Level and Asthma Control Test (ACT) in Detecting GINA-Defined Asthma Control in Treated Asthmatic Patients in Vietnam by Vinh Nguyen Nhu, Pham Le An, Niels H. Chavannes

    Published 2020-01-01
    “…FeNO has been used as a marker for Th2-mediated airway inflammation in asthma. There is evidence which recommends the use of this biomarker in asthma management. …”
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    Evaluation of a Global Initiative for Asthma Education and Implementation Program to Improve Asthma Care Quality (CARE4ALL): Protocol for a Multicenter, Single-Arm Study by Kewu Huang, Wenjun Wang, Ying Wang, Yanming Li, Xiaokai Feng, Huahao Shen, Chen Wang

    Published 2025-01-01
    “… BackgroundPoor symptom control and exacerbations of asthma diminish quality of life and pose a significant burden to patients and society. …”
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