Cost of Serum Versus Skin Allergy Testing Among Medicare Fee-for-Service Beneficiaries in the United States by Kenny Y. Kwong, Yang Z. Lu

“…Beneficiaries with any sIgE test, skin prick test, or intradermal skin test associated with ICD-10 codes of allergic rhinitis, asthma, and food allergy were included. Aggregate and per-beneficiary testing cost, number of allergens tested, and number of allergy-related specialist visits incurred were estimated by the testing patterns of sIgE only, skin prick only, intradermal only, skin prick and intradermal, and sIgE plus prick and/or intradermal. …”
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E3 ligase RNF128 restricts A. alternata-induced ILC2 activation and type 2 immune response in the murine lung by Chenghua Yan, Wendong Kuang, Guangqiang Ma, Feifei Guo, Liang Jin, Hongjiao Wan, Jinhua Zhu, Yongcui Liao, Haijun Tan, Liyuan Wang

“…Published data show that RNF128, an E3 ligase, promotes Th2 activation in the OVA-induced asthma model. Recent advances have shown that group 2 innate lymphoid cells (ILC2s) produce the cytokines IL-5 and IL-13 to mediate type 2 immune response. …”
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Impact of gas flaring on acute respiratory distress among pregnant women and newborn babies in Delta State Central Senatorial District, Nigeria by Omatseye Alero Akuirene, John Esimaje Moyegbone, Charity Omoikhekpen Chukumah, Mercy Ebiyemi Kalaroo, Josiah Obaghwerhievwo Adjene, Emmanuel Agbonomhen Agege, Joseph Onyedenyifa Odoko, Ezekiel Uba Nwose

“…Health professional reported that developing severe lung infection, release of black carbon and asthma sufferers were major risk factors to RDS. Conclusion: Findings showed that there was an increased prevalence of RDS among the study sub-population. …”
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Luteolin Attenuates IL-1β-Induced THP-1 Adhesion to ARPE-19 Cells via Suppression of NF-κB and MAPK Pathways by Wen-Chung Huang, Chian-Jiun Liou, Szu-Chuan Shen, Sindy Hu, Chien-Yu Hsiao, Shu-Ju Wu

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“Lung-on-a-chip” as an instrument for studying the pathophysiology of human respiration by Oksana A. Zhukova, Iuliia V. Ozerskaya, Dmitry V. Basmanov, Vsevolod Yu. Stolyarov, Vladimir G. Bogush, Vladimir V. Kolesov, Kirill A. Zykov, Gaukhar M. Yusubalieva, Vladimir P. Baklaushev

“…Besides the LoC imitating the hematoalveolar barrier, there are modifications for studying the specific pathophysiological processes, for the screening of medicinal products, for modeling specific diseases, for example, lung cancer, chronic obstructive pulmonary disease or asthma. In the present review, we have analyzed the existing types of LoC, the biomaterials used, the methods of detecting molecular processes within the microfluidic devices and the main directions of research to be conducted using the “lung-on-a-chip”.…”
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Systematic identification of the chemical components of leaves and roots of Didymocarpus heucherifolius Hand.-Mazz. based on UHPLC Q-Exactive Orbitrap MS technology coupled with mo... by Liangyin Shu, Shunli Xiao, Kailin Li, Huibin Luo, Meng Li, Qingrui Yang, Bowen Gao, Jiaxin Li, Fang Yan, Wei Cai

“…Species in this genus have long been used in folk medicine to treat various illnesses, including wounds, kidney stones, inflammations, asthma, influenza, etc. However, there are few studies on chemical components. …”
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Adherence to Mediterranean-Like Dietary Pattern in Association with Gastroesophageal Reflux Disease in Adolescents by Azam AhmadiVasmehjani, Sara Beigrezaei, Zahra Nafei, Nasrin Behniafard, Zahra Darabi, Amin Salehi-Abargouei, Majid Aflatoonian

“…Dietary intake was assessed using a food frequency method which included in a reliable and valid Global Asthma Network (GAN) core questionnaire. GERD symp­toms and the frequency of their occurrence over the last week were assessed using a validated GERD questionnaire. …”
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Hepatitis due to Coxsackie A virus in an adult: a case report by Likith Surendra, Varun Sharma, Milan Sivakumar, Tara Lanzendorf, Thomas C. Varkey, Kaivan Salehpour

“…His past medical history was significant for asthma, chronic back pain taking tramadol, cholecystitis status post cholecystectomy, and an ongoing workup for autoimmune hepatitis. …”
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Risk of pneumonia in patients with isolated minor rib fractures: a nationwide cohort study by Yu-Hsun Wang, Ming-Chih Chou, Sai-Wai Ho, Ying-Hock Teng, Shun-Fa Yang, Han-Wei Yeh, Chao-Bin Yeh

“…This nationwide cohort study investigated the association between IMRFs and the risk of pneumonia in patients with blunt chest traumas.Design Nationwide population-based cohort study.Setting Patients with IMRFs were identified between 2010 and 2011 from the Taiwan National Health Insurance Research Database.Participants Non-traumatic patients were matched through 1:8 propensity-score matching according to age, sex, and comorbidities (namely diabetes, hypertension, cardiovascular disease, asthma and chronic obstructive pulmonary disease (COPD)) with the comparison cohort. …”
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Home Medication Review among Patients with Chronic Diseases in Rural Villages of Pahang, Malaysia: A Case Report by Norny Syafinaz Ab Rahman, Nur Alyaa Anisa Mat Harom, Nor Ilyani Mohamed Nazar

“…The first case describes a 62-year-old single Malay female with multiple chronic conditions, including Type 2 diabetes mellitus (T2DM), hypertension, dyslipidemia, and bronchial asthma, managed with eight prescribed medications. …”
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Sevoflurane Inhibits the Th2 Response and NLRP3 Expression in Murine Allergic Airway Inflammation by Lixia Wang, Binshan Zha, Qiying Shen, Hongyun Zou, Cheng Cheng, Huimei Wu, Rongyu Liu

“…The NLRP3 independent of inflammasomes participated in the pathogenesis of allergic asthma in this model.…”
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Environmental burden of disease resulting from long-term nitrogen dioxide exposure in Germany by Paulina Sell, Dietrich Plass, Sarah Kienzler, Hajo Zeeb

“…We first conducted a systematic literature review to identify exposure–response functions (ERFs) which mathematically represent the association between NO2 exposure and the health outcomes: asthma, chronic obstructive pulmonary disease (COPD), type 2 diabetes mellitus (T2DM), ischemic heart disease, lung cancer, stroke, and cardiovascular and respiratory mortality. …”
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Retrospective evaluation of patients admitted to the intensive care unit due to obstetric reasons in terms of maternal near-miss, a five-year case-control study by Özgür Erdem, Süleyman Cemil Oğlak, İzzettin Toktaş, Seher Baydemir, Ahmet Yosunkaya, Ali Erdem

“…The frequency of co-morbidities (Diabetes mellitus, Hypertension, Asthma, Hypothyroidism, etc.) in patients diagnosed with MNM (n = 48; 26.67%) was found to be 5.5 times that of the control group (n = 25; 6.20%) (p < 0.001). …”
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Association of exposure to second-hand smoke during childhood with blood DNA methylation by Marta Cosin-Tomas, Thanh Hoang, Cancan Qi, Giulietta S. Monasso, Ryan Langdon, Simon Kebede Merid, Lucinda Calas, Paula de Prado-Bert, Rebecca Richmond, Vincent VW Jaddoe, Liesbeth Duijts, John Wright, Isabella Annesi-Maesano, Regina Grazuleviciene, Marianna Karachaliou, Gerard H. Koppelman, Erik Melén, Olena Gruzieva, Martine Vrijheid, Paul Yousefi, Janine F. Felix, Stephanie J. London, Mariona Bustamante

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Prevalence and Economic Impact of Acute Respiratory Failure in the Prehospital Emergency Medical Service of the Madrid Community: Retrospective Cohort Study by Ana María Cintora-Sanz, Cristina Horrillo-García, Víctor Quesada-Cubo, Ana María Pérez-Alonso, Alicia Gutiérrez-Misis

“…The anonymized medical records of patients treated with medical ALS, who received any of the following medical diagnoses, were extracted: ARF not related to chronic respiratory disease, ARF in chronic respiratory failure, exacerbations of COPD, APE, CHF, and bronchospasm (not from asthma or COPD). The prevalence of each pathology, its evolution from 2014 to 2020, and the economic impact of the Medical ALSs were calculated. …”
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Angiopoietin-2 and D-dimer add prognostic information to clinical risk in pulmonary arterial hypertension by Heather L. Clark, Daniel Lachant, Allison N. Light, Deborah Haight, Samia Lopia, Nigel Mackman, R. James White

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Olfactory impairment in Italian patients with chronic rhinosinusitis with nasal polyps: a patient-centered survey by Francesca Anastasi, Francesca Anastasi, Frank Rikki Mauritz Canevari, Frank Rikki Mauritz Canevari, Stefania Gallo, Giulia Gramellini, Enrico Heffler, Enrico Heffler, Ignazio La Mantia, Giulia Monti, Martina Ragusa, Alberto Macchi

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Clinical code usage in UK general practice: a cohort study exploring 18 conditions over 14 years by Christos Grigoroglou, Darren M Ashcroft, Evangelos Kontopantelis, David Reeves, Salwa S Zghebi, Rosa Parisi, Brian McMillan

“…Objective To assess the diagnostic Read code usage for 18 conditions by examining their frequency and diversity in UK primary care between 2000 and 2013.Design Population-based cohort studySetting 684 UK general practices contributing data to the Clinical Practice Research Datalink (CPRD) GOLD.Participants Patients with clinical codes for at least one of asthma, chronic obstructive pulmonary disease, diabetes, hypertension (HT), coronary heart disease, atrial fibrillation (AF), heart failure, stroke, hypothyroidism, chronic kidney disease, learning disability (LD), depression, dementia, epilepsy, severe mental illness (SMI), osteoarthritis, osteoporosis and cancer.Primary and secondary outcome measures For the frequency ranking of clinical codes, canonical correlation analysis was applied to correlations of clinical code usage of 1, 3 and 5 years. …”
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Association between weight-adjusted waist-index and symptoms of sleep apnea in US adults: results from 2015–2018 national health and nutrition examination survey by Edmore Madondo, Paddington T. Mundagowa, Ayesha Mukhopadhyay, Debra Bartelli, Yu Jiang, Fawaz Mzayek

“…The association between WWI and symptoms of sleep apnea was consistent across different age groups, gender, asthma, and physical activity groups. Conclusion WWI was positively associated with increased odds of sleep apnea symptoms and the association showed a dose–response relationship. …”
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How Does Indonesian Chronic Disease Patient Adhere to Their Treatment? A Cross-Sectional Analysis of 11,408 Subjects by Pradipta IS, Aprilio K, Ningsih YF, Pratama MAA, Gatera VA, Alfian SD, Iskandarsyah A, Abdulah R

“…Treatment nonadherence was notable in subjects with liver disease (61.8%), tuberculosis (59.8%), digestive diseases (57.9%), other lung diseases (56.8%), psychiatric diseases (51.6%), asthma (51.2%), and hypertension (50%). Treatment nonadherence was associated with socioeconomic-related factors of being aged 15– 65 years, living in rural areas, having history of formal education, and having a household size of 2– 6 people. …”
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