Calcium Handling in Airway Smooth Muscle: Mechanisms and Therapeutic Implications by Luke J Janssen

“…The changes that may occur in calcium-handling pathways in asthma and the opportunities for novel approaches to the treatment of asthma are also discussed.…”
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A current review on animal models of anti-asthmatic drugs screening by Shivam Singh, Sunita Kularia, Shivakshi Shukla, Mithilesh Singh, Manish Kumar, Ashish Kumar Sharma

“…Asthma is a chronic inflammatory respiratory condition characterised by airway constriction, smooth muscle spasm, and severe morbidity. …”
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Association of nutrients intake during pregnancy with the risk of allergic disease in offspring: a meta-analysis of prospective cohort studies by Hua Feng, Yan Chen, Xiujuan Xiong, Qunying Xu, Zhongwei Zhang, Qinghua Xi, Yongning Wu, Yuanan Lu

“…To investigate the role of nutrients intake during pregnancy with longitudinal development of rhinitis, asthma, eczema, wheeze, and food allergy in offspring. …”
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Assessing the impact of long-term inhaled corticosteroid therapy on patients with COVID-19 and coexisting chronic lung disease: A multicenter retrospective cohort study by Adela Pina Belmonte, Manuel Madrazo, Laura Piles, Manuel Rubio-Rivas, Lucía de Jorge Huerta, María Gómez Antúnez, Juan Francisco López Caleya, Francisco Arnalich Fernández, Martin Gericó-Aseguinolaza, Paula Maria Pesqueira Fontan, Nicolás Rhyman, Marina Prieto Dehesa, Juan Luis Romero Cabrera, Gema María García García, Gonzalo García-Casasola, Ane Labirua-Iturburu Ruiz, Francisco Javier Carrasco-Sánchez, Sara Martínez Hernández, Maria de los Reyes Pascual Pérez, José López Castro, José Luis Serrano Carrillo de Albornoz, José F. Varona, Ricardo Gómez-Huelgas, Juan-Miguel Antón-Santos, Carlos Lumbreras-Bermejo

“…# Background Patients with chronic lung disease (CLD), such as asthma or chronic obstructive pulmonary disease, were expected to have an increased risk of clinical manifestations and severity of COVID-19. …”
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Herbal Medicines for Asthmatic Inflammation: From Basic Researches to Clinical Applications by Fang Liu, Nan-Xia Xuan, Song-Min Ying, Wen Li, Zhi-Hua Chen, Hua-Hao Shen

“…Asthma is one of the most common chronic inflammatory disorders, associated with reversible airflow obstruction, airway hyperresponsiveness, and airway remodeling. …”
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Montelukast: More than a Cysteinyl Leukotriene Receptor Antagonist? by Gregory R. Tintinger, Charles Feldman, Annette J. Theron, Ronald Anderson

“…The prototype cysteinyl leukotriene receptor antagonist, montelukast, is generally considered to have a niche application in the therapy of exercise- and aspirin-induced asthma. It is also used as add-on therapy in patients whose asthma is poorly controlled with inhaled corticosteroid monotherapy, or with the combination of a long-acting β(2)-agonist and an inhaled corticosteroid. …”
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Oxidative balance score and its association with chronic inflammatory airway diseases and mortality: a population-based study by Zhuanbo Luo, Shiyu Chen, Peixu Chen, Feng Qiu, Weina Huang, Chao Cao

“…The CIAD included individuals with self-reported asthma, chronic bronchitis, or COPD. Mortality data up to December 31, 2019, was obtained from the National Death Index. …”
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Ventilatory Care in Status Asthmaticus by Robert J Smyth

“…Asthma continues to pose a significant medical problem in terms of both morbidity and mortality. …”
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IL-7 promotes integrated glucose and amino acid sensing during homeostatic CD4+ T cell proliferation by Seema Bachoo, Nancy Gudgeon, Rebecca Mann, Victoria Stavrou, Emma L. Bishop, Audrey Kelly, Alejandro Huerta Uribe, Jordan Loeliger, Corina Frick, Oliver D.K. Maddocks, Paul Lavender, Christoph Hess, Sarah Dimeloe

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Effect of Interleukin-15 on CD11b, CD54, and CD62L Expression on Natural Killer Cell and Natural Killer T-Like Cells in Systemic Lupus Erythematosus by Syh-Jae Lin, Ji-Yih Chen, Ming-Ling Kuo, Hsiu-Shan Hsiao, Pei-Tzu Lee, Jing-Long Huang

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Increased thyroxine levels of patients with allergic rhinitis by Violeta Lokaj-Berisha, Besa Gacaferri Lumezi

“…Abstract Allergic rhinitis and asthma are common respiratory conditions with complex etiologies involving genetic, environmental, and physiological factors. …”
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Benefits that Asthmatic Patients Receive after the Application of a Physiotherapeutic and Rehabilitative Treatment by Ismaray Sacerio González, Vivian Isabel Chávez Pérez, Belkis González Aguiar

“…Bronchial asthma continues to be the most common chronic disease in childhood. …”
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Vitamin D Regulates the Expression of Glucocorticoid Receptors in Blood of Severe Asthmatic Patients by Bassam Mahboub, Saba Al Heialy, Mahmood Yaseen Hachim, Rakhee K. Ramakrishnan, Ashraf Alzaabi, Rania Medhat Seliem, Laila Ibraheem Salameh, Sameen Masooma Toor, Fathelrahman Salem Shendi, Ola Mohamed Al Ali, Basil Khalid Safarini, Wafa Taleb Erabia, Rabih Halwani, Qutayba Hamid

“…Vitamin D (VitD) deficiency is a significant public health concern in many areas around the globe and has been associated with many immune-mediated diseases, including asthma. Severe asthma has been linked to a decreased glucocorticoid receptor (GR) ratio (GR-α/GR-β ratio), indicating steroid hyporesponsiveness. …”
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New Role of Adult Lung c-kit+ Cells in a Mouse Model of Airway Hyperresponsiveness by Giuseppe Spaziano, Donato Cappetta, Konrad Urbanek, Elena Piegari, Grazia Esposito, Maria Matteis, Manuela Sgambato, Gioia Tartaglione, Rosa Russo, Raffaele De Palma, Francesco Rossi, Antonella De Angelis, Bruno D’Agostino

“…Structural changes contribute to airway hyperresponsiveness and airflow obstruction in asthma. Emerging evidence points to the involvement of c-kit+ cells in lung homeostasis, although their potential role in asthma is unknown. …”
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Membrane Currents in Airway Smooth Muscle: Mechanisms and Therapeutic Implications by Luke J Janssen

“…Finally, how the relationship between ion channels and ASM function/dysfunction may relate to the treatment of asthma and related breathing disorders is discussed.…”
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Airbag Pneumonitis by Raghav Govindarajan, Gustavo Ferrer, Laurence A. Smolley, Eduardo Araujo Oliveira, Franck Rahaghi

“…Airbags have been implicated in a spectrum of pulmonary conditions ranging from exacerbation of asthma, reactive airway diseases to new onset asthma. …”
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Newborn Screening Saves Lives but Cannot Replace the Need for Clinical Vigilance by F. Neemuchwala, M. Taki, E. Secord, S. Z. Nasr

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Effect of Tumor Necrosis Factor Family Member LIGHT (TNFSF14) on the Activation of Basophils and Eosinophils Interacting with Bronchial Epithelial Cells by Huai Na Qiu, Chun Kwok Wong, Jie Dong, Christopher Wai-Kei Lam, Zhe Cai

“…Allergic asthma can cause airway structural remodeling, involving the accumulation of extracellular matrix and thickening of smooth muscle. …”
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Role of macrophage migration inhibitory factor (MIF) in allergic and endotoxin-induced airway inflammation in mice by M. Korsgren, L. Källström, L. Uller, T. Bjerke, F. Sundler, C. G. A. Persson, O. Korsgren

“…Macrophage migration inhibitory factor (MIF) has recently been forwarded as a critical regulator of inflammatory conditions, and it has been hypothesized that MIF may have a role in the pathogenesis of asthma and chronic obstructive pulmonary disease (COPD). …”
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Respiratory patient experience of measures to reduce risk of COVID-19: findings from a descriptive cross-sectional UK wide survey by Andrew Cumella, Nicholas S Hopkinson, Michael Laffan, Joe Farrington-Douglas, Keir EJ Philip

“…Objectives To assess the experience of people with long-term respiratory conditions regarding the impact of measures to reduce risk of COVID-19.Design Analysis of data (n=9515) from the Asthma UK and British Lung Foundation partnership COVID-19 survey collected online between 1 and 8 April 2020.Setting Community.Participants 9515 people with self-reported long-term respiratory conditions. 81% female, age ranges from ≤17 years to 80 years and above, from all nations of the UK. …”
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