Schisandrin B Attenuates Airway Inflammation by Regulating the NF-κB/Nrf2 Signaling Pathway in Mouse Models of Asthma by Yaqin Chen, Yu Kong, Qili Wang, Jian Chen, Hua Chen, Huihui Xie, Lan Li

“…Background. Asthma is a complex inflammatory disorder that plagues a large number of people. …”
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Genetic polymorphisms (FTO rs9939609 and TMEM18 rs6548238), adipokines (leptin and adiponectin) and adiposity in children and adolescents with asthma by Marta Evangelho Machado, Luis C. Porto, Jeane S. Nogueira, Clemax C. Sant´Anna, José R. Lapa e Silva

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Polymorphisms of Tumor Necrosis Factor-α, Transforming Growth Factor-β, and Interleukin-10 in Asthma Associated with Olive Pollen Sensitization by Blanca Cárdaba, David Calzada, Selene Baos, Miriam Aguerri, Joaquín Quiralte, Carlos Lahoz

“…Sensitization to specific olive pollen-allergens (Ole e 2 and 10) has been correlated with a clinical pattern of asthma. This study analyzes the association between several polymorphims of TNFA (G-308A, C-857T, and C-1031T), IL10 (C-571A and A-1117G), and TGFB (C-509-T) and these sensitizations. …”
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Acute Bronchiolitis To Pediatric Inpatient Clinic In Patients Under 2 Years Old, Installed with Diagnosis Investigation of the Relationship of Bronchiolitis and Asthma by Selin Kuzucu, İpek Türktaş, Tuğba Bedir Demirdağ, Meltem Polat, Hasan Tezer, Anıl Tapısız, Nazmi Mutlu Karakaş, Ayşe Tana Aslan, Hakan Tüzün

“…Disease severity was assessed using the bronchiolitis severity score developed by the Turkish Thoracic Society. The asthma risk was evaluated using the modified Asthma Predictive Index (mAPI) designed for predicting future asthma in bronchiolitis cases. …”
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CEACAM5 exacerbates asthma by inducing ferroptosis and autophagy in airway epithelial cells through the JAK/STAT6-dependent pathway by Si Liu, Li Chen, Yunxiao Shang

“…Objectives Asthma, a prevalent chronic disease, poses significant health threats and burdens healthcare systems. …”
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Bridging the gap: access to health care and control of type 2 diabetes mellitus, hypertension and bronchial asthma among Egyptian women by Eman Ibrahim Elmeshmeshy, Basma Abdelaziz, Saeed Soliman

Subjects: “…Hypertension and bronchial asthma…”
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Mixed Pulmonary Infection, Asthma, and Nephrotic Syndrome in a Patient Diagnosed with Selective IgA Deficiency: A Case Report by Yan C, Qiu J, Pan X, Huang X, Pan L, Wang C, Mao M

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March1 E3 Ubiquitin Ligase Modulates Features of Allergic Asthma in an Ovalbumin-Induced Mouse Model of Lung Inflammation by Osama A. Kishta, Antoine Sabourin, Leora Simon, Toby McGovern, Maxime Raymond, Tristan Galbas, Abdelilah Majdoubi, Satoshi Ishido, James G. Martin, Jacques Thibodeau

“…Given the key roles of MHC class II and CD86 in T cell activation and to get further insights into the development of allergic inflammation, we asked whether March1 deficiency exacerbates or attenuates features of allergic asthma in mice. Herein, we used an acute model of allergy to compare the asthmatic phenotype of March1-deficient and -sufficient mice immunized with ovalbumin (OVA) and later challenged by intranasal instillation of OVA in the lungs. …”
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High protein diet increases the risk of allergic sensitization but not asthma in mice through modulation of the cytokine milieu toward Th2 bias by Waleed Al-Herz, MD, Fawaz Azizieh, PhD, Raj Raghupathy, PhD

“…In this study we aimed to determine the effect of high protein (HP) diet on allergic sensitization, cytokine profile, and asthma in mice. Methods: Seven- to eight-week old female BALB/c mice were fed either normal (ND) or HP diet and were sensitized with ovalbumin intraperitoneally followed by intranasal challenge. …”
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Assessment of Asthma Control and Quality of Life among Asthmatic Patients Attending Armed Forces Referral and Teaching Hospital, Addis Ababa, Ethiopia by Tesfalidet Gebremeskel Zeru, Ephrem Engidawork, Alemseged Beyene Berha

“…Background. The primary goal of asthma management is to achieve good asthma control. …”
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Patients With Isolated Nail Psoriasis Are at Increased Risk for Asthma Compared to Controls in a Retrospective Cohort Study at a Single Academic Institution by Rachel C Hill, Rhiannon C Miller, Shari R Lipner

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A blinded comparison of fluticasone propionate with budesonide via powder devices in adult patients with moderate-to-severe asthma: a clinical evaluation by N. Ringdal, P. Swinburn, R. Backman, P. Plaschke, A. P. Sips, P. Kjaersgaard, G. Bratten, T. A. J. Harris

“…In Vitro and in vivo data have demonstrated that there are detectable differences between inhaled corticosteroids commonly used to treat asthma. However, controversy still remains as to whether these differences translate into clinical benefits. …”
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Asthma and Chronic Obstructive Pulmonary Disease Guideline Implementation: Lessons Learned on Recruitment of Primary Care Physicians to a Knowledge Translation Study by Louis-Philippe Boulet, Paul Hernandez, Hollie Devlin, Marni A Freeman, Samir Gupta

“…BACKGROUND: Implementation of current clinical practice guidelines in asthma and chronic obstructive pulmonary disease (COPD) is suboptimal. …”
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Results from a UK consensus about the optimal prescribing of medium strength triple therapy in uncontrolled adult asthma patients in the NHS by Richard E. K. Russell, Darush Attar-Zadeh, Natalie Harper, Fiona Mosgrove, Laura Rush, Dave Singh

Subjects: “…asthma…”
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Association between oxidative balance score and all-cause, CVD and respiratory-related mortality in the US older adults of asthma patients with diabetes by Chang Liu, Dan Liang, Dan Liang, Guoan Xiang, Xuanbo Zhao, Kun Xiao, Lixin Xie, Lixin Xie

“…We did not observe OBS could reduce respiratory-related mortality in older asthma patients with diabetes. RCS analysis indicated a linear and inverse association between the OBS and all-cause and CVD mortality. …”
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Global, regional and national burden of asthma attributable to NO2 from 1990 to 2021: an analysis from the Global Burden of Disease Study 2021 by Chunyi Zhang, Jian Sun, Jingli Li, E Qin, Lingjing Liu, Guimei Pu

“…Objectives This study aims to systematically assess the global, regional, and national burden of asthma attributable to nitrogen dioxide (NO₂) pollution.Design and setting Analysis of population-level data from 1990 to 2021 obtained from the Global Burden of Disease Study 2021, covering 204 countries and territories.Participants Participants included patients with asthma attributable to NO₂ pollution.Main outcomes and measures Asthma-related disability-adjusted life-years (DALYs) and age-standardised DALY rates (ASDR) attributable to NO₂ pollution across 204 countries and territories. …”
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Perceptions, practices, and experiences of asthma patients and community pharmacists on short-acting beta-2 agonists inhaler use: A qualitative study by Rabia Hussain, Zhe Chi Loh, Bayan Faisal Ababneh, Jaya Muneswarao, Siew Chin Ong, Bandana Saini, Anees ur-Rehman, Vibhu Paudyal

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METTL3/miR-192-5p/SCD1 Axis Regulates Lipid Metabolism to Affect T Cell Differentiation in Asthma by Zhengrong Chen, Dingwei Yan, Suyu Guo, Yiyi Song, Xinxing Zhang, Wenjing Gu, Heting Dong, Li Huang

“…Conclusion: These results suggest that METTL3/miR-192-5p/SCD1 axis regulates lipid metabolism and affects T cell differentiation, thus affecting asthma progression. This study may provide novel insights into the pathogenesis of asthma and a new treatment strategy.…”
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Anti-IL-5 treatment, but not neutrophil interference, attenuates inflammation in a mixed granulocytic asthma mouse model, elicited by air pollution by Joyceline De Volder, Annelies Bontinck, Valerie Haelterman, Louis Boon, Guy F. Joos, Guy G. Brusselle, Tania Maes

Subjects: “…Pollutant-aggravated allergic asthma…”
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Deciphering the Immune Subtypes and Signature Genes: A Novel Approach Towards Diagnosing and Prognosticating Severe Asthma Through Interpretable Machine Learning by Yue Hu, Yating Lin, Bo Peng, Chunyan Xiang, Wei Tang

“…Asthma, a pervasive pulmonary disorder, affects countless individuals globally. …”
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