CEACAM5 exacerbates asthma by inducing ferroptosis and autophagy in airway epithelial cells through the JAK/STAT6-dependent pathway by Si Liu, Li Chen, Yunxiao Shang

“…Objectives Asthma, a prevalent chronic disease, poses significant health threats and burdens healthcare systems. …”
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Bridging the gap: access to health care and control of type 2 diabetes mellitus, hypertension and bronchial asthma among Egyptian women by Eman Ibrahim Elmeshmeshy, Basma Abdelaziz, Saeed Soliman

Subjects: “…Hypertension and bronchial asthma…”
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March1 E3 Ubiquitin Ligase Modulates Features of Allergic Asthma in an Ovalbumin-Induced Mouse Model of Lung Inflammation by Osama A. Kishta, Antoine Sabourin, Leora Simon, Toby McGovern, Maxime Raymond, Tristan Galbas, Abdelilah Majdoubi, Satoshi Ishido, James G. Martin, Jacques Thibodeau

“…Given the key roles of MHC class II and CD86 in T cell activation and to get further insights into the development of allergic inflammation, we asked whether March1 deficiency exacerbates or attenuates features of allergic asthma in mice. Herein, we used an acute model of allergy to compare the asthmatic phenotype of March1-deficient and -sufficient mice immunized with ovalbumin (OVA) and later challenged by intranasal instillation of OVA in the lungs. …”
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Comparative analysis of ambient, in-home, and personal exposures reveals associations between breathing zone pollutant levels and asthma exacerbations in high-risk children by Camille M. Moore, Jonathan Thornburg, Elizabeth A. Secor, Katharine L. Hamlington, Allison M. Schiltz, Kristy L. Freeman, Jamie L. Everman, Tasha E. Fingerlin, Andrew H. Liu, Max A. Seibold

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Patients With Isolated Nail Psoriasis Are at Increased Risk for Asthma Compared to Controls in a Retrospective Cohort Study at a Single Academic Institution by Rachel C Hill, Rhiannon C Miller, Shari R Lipner

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Ecofriendly colorimetric set-up coupled with mathematical filtration strategy for simultaneous determination of ipratropium and fenoterol in their novel anti-asthmatic metered dose... by Salma N. Ali, Hoda M. Marzouk, Ahmed S. Fayed, Samah S. Saad

Subjects: “…Asthma…”
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Punicalagin attenuated allergic airway inflammation via regulating IL4/IL-4Rα/STAT6 and Notch- GATA3 pathways by Yu Li, Li Jianying

Subjects: “…asthma…”
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High protein diet increases the risk of allergic sensitization but not asthma in mice through modulation of the cytokine milieu toward Th2 bias by Waleed Al-Herz, MD, Fawaz Azizieh, PhD, Raj Raghupathy, PhD

“…In this study we aimed to determine the effect of high protein (HP) diet on allergic sensitization, cytokine profile, and asthma in mice. Methods: Seven- to eight-week old female BALB/c mice were fed either normal (ND) or HP diet and were sensitized with ovalbumin intraperitoneally followed by intranasal challenge. …”
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Assessment of Asthma Control and Quality of Life among Asthmatic Patients Attending Armed Forces Referral and Teaching Hospital, Addis Ababa, Ethiopia by Tesfalidet Gebremeskel Zeru, Ephrem Engidawork, Alemseged Beyene Berha

“…Background. The primary goal of asthma management is to achieve good asthma control. …”
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A blinded comparison of fluticasone propionate with budesonide via powder devices in adult patients with moderate-to-severe asthma: a clinical evaluation by N. Ringdal, P. Swinburn, R. Backman, P. Plaschke, A. P. Sips, P. Kjaersgaard, G. Bratten, T. A. J. Harris

“…In Vitro and in vivo data have demonstrated that there are detectable differences between inhaled corticosteroids commonly used to treat asthma. However, controversy still remains as to whether these differences translate into clinical benefits. …”
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Asthma and Chronic Obstructive Pulmonary Disease Guideline Implementation: Lessons Learned on Recruitment of Primary Care Physicians to a Knowledge Translation Study by Louis-Philippe Boulet, Paul Hernandez, Hollie Devlin, Marni A Freeman, Samir Gupta

“…BACKGROUND: Implementation of current clinical practice guidelines in asthma and chronic obstructive pulmonary disease (COPD) is suboptimal. …”
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Global, regional and national burden of asthma attributable to NO2 from 1990 to 2021: an analysis from the Global Burden of Disease Study 2021 by Chunyi Zhang, Jian Sun, Jingli Li, E Qin, Lingjing Liu, Guimei Pu

“…Objectives This study aims to systematically assess the global, regional, and national burden of asthma attributable to nitrogen dioxide (NO₂) pollution.Design and setting Analysis of population-level data from 1990 to 2021 obtained from the Global Burden of Disease Study 2021, covering 204 countries and territories.Participants Participants included patients with asthma attributable to NO₂ pollution.Main outcomes and measures Asthma-related disability-adjusted life-years (DALYs) and age-standardised DALY rates (ASDR) attributable to NO₂ pollution across 204 countries and territories. …”
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Perceptions, practices, and experiences of asthma patients and community pharmacists on short-acting beta-2 agonists inhaler use: A qualitative study by Rabia Hussain, Zhe Chi Loh, Bayan Faisal Ababneh, Jaya Muneswarao, Siew Chin Ong, Bandana Saini, Anees ur-Rehman, Vibhu Paudyal

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METTL3/miR-192-5p/SCD1 Axis Regulates Lipid Metabolism to Affect T Cell Differentiation in Asthma by Zhengrong Chen, Dingwei Yan, Suyu Guo, Yiyi Song, Xinxing Zhang, Wenjing Gu, Heting Dong, Li Huang

“…Conclusion: These results suggest that METTL3/miR-192-5p/SCD1 axis regulates lipid metabolism and affects T cell differentiation, thus affecting asthma progression. This study may provide novel insights into the pathogenesis of asthma and a new treatment strategy.…”
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Anti-IL-5 treatment, but not neutrophil interference, attenuates inflammation in a mixed granulocytic asthma mouse model, elicited by air pollution by Joyceline De Volder, Annelies Bontinck, Valerie Haelterman, Louis Boon, Guy F. Joos, Guy G. Brusselle, Tania Maes

Subjects: “…Pollutant-aggravated allergic asthma…”
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Deciphering the Immune Subtypes and Signature Genes: A Novel Approach Towards Diagnosing and Prognosticating Severe Asthma Through Interpretable Machine Learning by Yue Hu, Yating Lin, Bo Peng, Chunyan Xiang, Wei Tang

“…Asthma, a pervasive pulmonary disorder, affects countless individuals globally. …”
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Migrasomes derived from human umbilical cord mesenchymal stem cells: a new therapeutic agent for ovalbumin-induced asthma in mice by Weifeng Gu, Tingting Zheng, Wen Li, Xinkai Luo, Xiaowei Xu, Ying Wang, Chaoming Mao, Yongbin Ma, Liyang Dong

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Montelukast Use and Patterns of Ambulatory Care among Asian versus Non-Asian Adult Patients with Asthma and/or Allergic Rhinitis in the United States by Joseph Vasey, Shalini Bagga, Huan Huang, Tongsheng Wang, David Thompson

“…**Background:** Asthma and allergic rhinitis (AR) are inflammatory conditions that are similar in pathophysiology. …”
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Adjustable Maintenance Dosing with Budesonide/Formoterol Reduces Asthma Exacerbations Compared with Traditional Fixed Dosing: A Five-Month Multicentre Canadian Study by J Mark FitzGerlad, Malcolm R Sears, Louis-Philippe Boulet, Allan B Becker, Andrew R McIvor, Pierre Ernst, Natasha M Smiljanic-Georgijev, Joanna SM Lee

“…BACKGROUND: Adjustable maintenance dosing with budesonide/formoterol in a single inhaler (Symbicort, AstraZeneca, Lund, Sweden) may provide a convenient means of maintaining asthma control with the minimum effective medication level.…”
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Isotype diversity of antibodies specific for component allergens in the context of allergic diseases: eosinophilic esophagitis (EoE), asthma, and the alpha-gal syndrome (AGS) by Thomas A. E. Platts-Mills, Matthew H. MacCallum, Jeffrey M. Wilson, Lisa J. Workman, Elizabeth A. Erwin

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