Peptide-Based Vaccination Therapy for Rheumatic Diseases by Bin Wang, Shiju Chen, Qing Zheng, Yuan Liu, Guixiu Shi

“…Tremendous efforts have been made to develop effective peptide-based vaccinations against rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), while studies in other rheumatic diseases are still limited. …”
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Therapeutic Benefit in Rheumatoid Cachexia Illustrated Using a Novel Primary Human Triple Cell Coculture Model by Tracey Ollewagen, Gareth S. Tarr, Kathryn H. Myburgh, Helmuth Reuter, Carine Smith

“…The loss of muscle mass in rheumatoid arthritis (RA), termed rheumatoid cachexia, is predicted to result from the complex interactions between different cell types involved in the maintenance of skeletal muscle mass, namely, myoblasts, fibroblasts, and macrophages. …”
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Perception of the Importance of Inherited Genetics and Lifestyle on the Development of Chronic Diseases: A UK Cross‐Sectional Survey by Aamir Hussain, Lourdes Santos‐Merx, Mariasole Da Boit

“…Moreover, the majority of the respondents chose lifestyle over inherited genes as most important factor for cancer, cardiovascular disease and Type 2 Diabetes development (50.8% vs. 29.6%, 79% vs. 11.9%, 85.7% vs. 9.6%; respectively), while 60.6% of respondents selected inherited genes for rheumatoid arthritis (p < 0.05). Knowledge about genes or a healthy lifestyle did not influence the selection of lifestyle as the most important factor (p > 0.05). …”
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In silico data mining of large-scale databases for the virtual screening of human interleukin-2 inhibitors by Halim Sobia Ahsan, Zaheer-Ul-Haq, Khan Ajmal, Al-Rawahi Ahmed, Al-Harrasi Ahmed

“…Uncontrolled activated T cells play a key role in the pathophysiology by stimulating inflammation and autoimmune diseases like arthritis, psoriasis and Crohn’s disease. T cells activation can be suppressed either by preventing IL-2 production or blocking the IL-2 interaction with its receptor. …”
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Medical cannabis in the management of musculoskeletal pain: a systematic review of clinical trials by Przemysław Płatek, Laura Piejko

“…Recent scientific findings suggest that cannabinoids may be therapeutically beneficial for conditions such as neurodegenerative disorders, seizures, nausea and vomiting, insomnia, neuropathic pain, excessive muscle tension, fibromyalgia, osteoarthritis (OA), rheumatoid arthritis (RA), and chronic wounds. Aims: The aim of this study was to summarize the current state of knowledge regarding the therapeutic potential of medical cannabis in the management of musculoskeletal pain. …”
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METTL3 Attenuates LPS-Induced Inflammatory Response in Macrophages via NF-κB Signaling Pathway by Jinghua Wang, Shushan Yan, Hongying Lu, Shufeng Wang, Donghua Xu

“…However, little is known of the role and underlying mechanism of METTL3 in rheumatoid arthritis (RA). The aim of the present study is to elucidate the function and potential mechanism of METTL3 in RA pathogenesis. …”
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Reverse shoulder arthroplasty in revision surgery-Indications and results. by Patricia Bergert, Ralf Henkelmann, Pierre Hepp, Jan Theopold

“…Based on the indications for SRSA, patients were categorized into post-traumatic shoulder arthritis, humeral head necrosis, failed proximal humerus fractures, failed proximal humerus osteosynthesis, prostheses loosening, and infection groups.…”
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Mode of Presentation and Associated Autoimmune Diseases in Children with Autoimmune Hepatitis by Nelgin Gerenli, Coşkun Çeltik

“…There was an associated autoimmune or auto-inflammatory disease in 35% of the patients, 12% had vitiligo, 6% had celiac disease, 6% had juvenile idiopathic arthritis, 6% had Familial Mediterranean Fever, and one patient had both type-1diabetes mellitus and Hashimoto thyroiditis (HT). …”
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Management of a Novel Autoimmune Disease, COPA Syndrome, in Pregnancy by Archana Ayyar, Rachel D. Seaman, Kalpalatha Guntupalli, Mary C. Tolcher

“…This disease manifests in childhood as pulmonary hemorrhage, arthritis, and renal disease. Case. We present a case of obstetric management of a 20-year-old nulligravida patient with a diagnosis of COPA syndrome. …”
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Analysis of Publications on Psoriasis and Tuberculosis by Sevil Alkan, İrem Şahinoğlu, Mustafa Serhat Şahinoğlu

“…This study recommends focusing more on tuberculosis, especially in psoriasis and psoriatic arthritis patients receiving anti-TNF therapy.…”
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Identification of Signal Pathways and Hub Genes of Pulmonary Arterial Hypertension by Bioinformatic Analysis by Rui-Qi Wei, Wen-Mei Zhang, Zhe Liang, Chunmei Piao, Guangfa Zhu

“…Significant KEGG pathway enrichment included ribosome biogenesis in eukaryotes, RNA transport, proteoglycans in cancer, dilated cardiomyopathy, rheumatoid arthritis, vascular smooth muscle contraction, focal adhesion, regulation of the actin cytoskeleton, and hypertrophic cardiomyopathy. …”
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The Critical Role of Bach2 in Shaping the Balance between CD4+ T Cell Subsets in Immune-Mediated Diseases by Lingyi Yang, Shuli Chen, Qiuyu Zhao, Ying Sun, Hong Nie

“…Genetic variations within Bach2 locus are associated with numerous immune-mediated diseases including multiple sclerosis (MS), rheumatoid arthritis (RA), chronic pancreatitis (CP), type 2 chronic airway inflammation, inflammatory bowel disease (IBD), and type 1 diabetes. …”
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Biologics in ocular inflammatory diseases – Experience from a tertiary referral eye care center in South India by Kalpana Babu, PG Padmapriya, Anand P Rao, Ramesh Jois

“…In this subgroup, panuveitis was the most common anatomic subtype (61.1%) and juvenile idiopathic arthritis was the most common etiology (27.7%). The most commonly used biologic in this study was adalimumab (36.84%). …”
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“Etiology and CT pattern in patients with interstial lung disease”: shift in the trends? by Abhishek Samdesi, Alamelu Haran, Navya Chinnaswamy Narayanaswamy

“…Most common CTD was systemic sclerosis (n = 23, 22.11%) and rheumatoid arthritis (n = 20, 19.23%). Second most common etiology was Idiopathic Pulmonary Fibrosis (IPF) (n=15, 14.42%). …”
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Quantitative Analysis of Multicomponents in Qufeng Zhitong Capsule and Application of Network Pharmacology to Explore the Anti-Inflammatory Activity of Focused Compounds by Mengjie Xue, Yuting Zhao, Ying Cui, Jing Yang, Yuefei Wang, Xin Chai

“…Qufeng Zhitong capsule (QZC) is a well-known Chinese patent medicine that has been widely applied for the clinical treatment of rheumatoid arthritis and other inflammatory diseases. To date, its material basis is still unclear, which has greatly limited its clinical application. …”
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The prevalence and evidence-based management of needle fear in adults with chronic disease: A scoping review. by Emily Duncanson, Richard K Le Leu, Lisa Shanahan, Luke Macauley, Paul N Bennett, Rick Weichula, Stephen McDonald, Anne L J Burke, Kathryn L Collins, Anna Chur-Hansen, Shilpanjali Jesudason

“…The following chronic diseases were included: arthritis, asthma, chronic back pain, cancer, cardiovascular disease, chronic obstructive pulmonary disease, diabetes, and mental illness, or kidney failure. …”
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Subcritical water extraction of dandelion (Taraxacum officinale L.) flowers: Influence of temperature on polyphenols content and antioxidant activity by Brezo-Borjan Tanja Ž., Švarc-Gajić Jaroslava V.

“…Described as non-toxic, the herb has been consumed in various forms as a valuable source of nutrients, minerals and vitamins, the consumption of which may help prevent or reduce the risk of complex diseases such as cancer, obesity, arthritis, hepatitis, cardiovascular and gastrointestinal disorders. …”
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Iguratimod prevents renal fibrosis in unilateral ureteral obstruction model mice by suppressing M2 macrophage infiltration and macrophage–myofibroblast transition by Yueyuan Zhou, Zhilan Li, Shenyi Yu, Xuan Wang, Tingting Xie, Weiru Zhang

“…Iguratimod is a novel synthetic, small-molecule immunosuppressive agent used to treat rheumatoid arthritis. Through ongoing exploration of its role and mechanisms of action, iguratimod has been observed to have antifibrotic effects in the lung and skin; however, its effect on renal fibrosis remains unknown. …”
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Significantly improving the solubility and anti-inflammatory activity of fenofibric acid with native and methyl-substituted beta-cyclodextrins via complexation by Rajaram Rajamohan, Perumal Muthuraja, Kuppusamy Murugavel, Murali Krishnan Mani, D. S. Prabakaran, Jeong Hyun Seo, Tabarak Malik, Yong Rok Lee

“…Furthermore, inflammatory arthritis stands out as the most prevalent chronic inflammatory disease globally. …”
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The Causal Relationship between Immune-Mediated Inflammatory Diseases and Aortic Aneurysm: A Bidirectional Two-Sample Mendelian Randomization Study by Sijia Sun, Jie Li, Mengxian Sun, Jie He, Songtao Tan, Ge Wang, Yuan Zheng, Xiaoping Fan

“…The causal estimates obtained using the IVW method revealed a significant association between genetically predicted AA and rheumatoid arthritis (RA; OR = 1.06, 95% CI = 1.01–1.12, P=0.029). …”
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