Nr4a1 and Nr4a3 redundantly control clonal deletion and contribute to an anergy-like transcriptome in auto-reactive thymocytes to impose tolerance in mice by Hailyn V. Nielsen, Letitia Yang, James L. Mueller, Alexander J. Ritter, Ryosuke Hiwa, Irina Proekt, Elze Rackaityte, Dominik Aylard, Mansi Gupta, Christopher D. Scharer, Mark S. Anderson, Byron B. Au-Yeung, Julie Zikherman

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Assessment of liver fibrosis by acoustic radiation force impulse elastography in rheumatic disease patients on long-term methotrexate treatment by Arindam Nandy Roy, Gayatri Senapathy, Vijay Kumar Bongu, Yarram Ashok Kumar, Syeda Sana Fatima, Regina Lata Thadigiri

“…The mean ARFI values of different rheumatic disease patients were 1.13 (0.0), 1.26 (0.19), 1.16 (0.15), 0.945 (0.21) for Rhupus, rheumatoid arthritis, psoriatic arthritis and Sjogren's syndrome, respectively. …”
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Evaluation of Tele-rheumatology during the COVID-19 Pandemic in Asian Population: A Pilot Study by Amit Sandhu, Amit Agarwal, Paramvir Kaur, Meenakshi Sharma, Harnoor Sra, Manvi Singh, Nishant Jaiswal, Anil Chauhan, Anju Gupta, Meenu Singh

“…Objective. Rheumatoid arthritis (RA) is a chronic autoimmune condition associated with a potential for deformities. …”
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A Rare Side Effect due to TNF-Alpha Blocking Agent: Acute Pleuropericarditis with Adalimumab by Hakan Ozkan, Ahmet Seckin Cetinkaya, Tekin Yildiz, Tahsin Bozat

“…Tumor necrosis factor-alpha antagonism is an important treatment strategy in patients with rheumatoid arthritis, psoriatic arthritis, vasculitis, and ankylosing spondylitis. …”
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Definition of Nonresponse to Analgesic Treatment of Arthritic Pain: An Analytical Literature Review of the Smallest Detectable Difference, the Minimal Detectable Change, and the Mi... by Melissa E. Stauffer, Stephanie D. Taylor, Douglas J. Watson, Paul M. Peloso, Alan Morrison

“…Our objective was to develop a working definition of nonresponse to analgesic treatment of arthritis, focusing on the measurement of pain on the 0–100 mm pain visual analog scale (VAS). …”
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Enteropathic Spondyloarthritis: From Diagnosis to Treatment by Rosario Peluso, Matteo Nicola Dario Di Minno, Salvatore Iervolino, Francesco Manguso, Giuseppina Tramontano, Pasquale Ambrosino, Carmela Esposito, Antonella Scalera, Fabiana Castiglione, Raffaele Scarpa

“…Enteropathic arthritis (EA) is a spondyloarthritis (SpA) which occurs in patients with inflammatory bowel diseases (IBDs) and other gastrointestinal diseases. …”
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Traumatic Separation of Bipartite Patella Underlying Gout by Eun Seok Choi, Jae Ang Sim, Jae Yun Go, Young Gon Na

“…Gouty arthritis is a common crystal arthropathy, but gout tophus in the bipartite patella is a rare condition. …”
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Construct validity and responsiveness of ASAS Health Index assessed in two longitudinal studies of tumour necrosis factor alpha inhibitor initiation and dose reduction in patients... by Merete Lund Hetland, Inge Juul Sørensen, Mikkel Østergaard, Mikael Boesen, Susanne Juhl Pedersen, Sara Nysom Christiansen, Ole Rintek Madsen, Mette Klarlund, Marie Wetterslev, Mate Lorincz, Mads Bakkegaard, Anne Duer, Kasper Kjærulf Gosvig

“…Background The Assessment of SpondyloArthritis international Society Health Index (ASAS HI) is a novel questionnaire of global functioning for patients with axial spondyloarthritis (SpA).Objective The objective was to assess the construct validity, discriminatory ability and responsiveness of ASAS HI in relation to patient-reported outcome measures (PROMs), MRI and radiography.Methods Data from two longitudinal studies with tumour necrosis factor inhibitor (TNFi) initiation (novel MRI And biomarkers in Golimumab-treated patients with axial spondyloarthritis (MANGO): n=45) respectively tapering (Dose adjustment of Biological treatment in patients with SpA (DOBIS): n=106) were used. …”
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TLR2 Elicits IL-17-Mediated RANKL Expression, IL-17, and OPG Production in Neutrophils from Arthritic Mice by Viktoriya Milanova, Nina Ivanovska, Petya Dimitrova

“…We conclude that TLR2 regulates the destructive potential of neutrophils and its targeting might limit joint alterations in arthritis.…”
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Association of COMT Val158Met Polymorphism with Fibromyalgia in Khartoum State, Sudan by Safaa Mamoun Abdelmageid, Faisal Mousa Alamir, Hassan Yousif Abdelrahman, Hind Mohamed Abushama

“…The mean age of the rheumatoid arthritis patients and healthy individuals was 31.3 ± 7.5 and 38.6 ± 11.2, respectively. …”
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Characterization of the Hypercitrullination Reaction in Human Neutrophils and Other Leukocytes by Yebin Zhou, Tiziana Di Pucchio, Gary P. Sims, Nanette Mittereder, Tomas Mustelin

“…Autoantibodies against citrullinated proteins are diagnostic for rheumatoid arthritis. However, the molecular mechanisms driving protein citrullination in patients with rheumatoid arthritis remain poorly understood. …”
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Isolated Sporothrix schenckii Monoarthritis by Aram Barbaryan, Wissam El Atrouni, Stefania Bailuc, Matthew W. Jones, Maharshi Bhakta, Khaldoun Haj Mahmoud, Aibek E. Mirrakhimov

“…Sporothrix schenkii sensu lato is a rare cause of arthritis. Its course is indolent with lack of constitutional symptoms resulting in delayed presentation and diagnosis. …”
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Thrombin Promotes Matrix Metalloproteinase-13 Expression through the PKCδ/c-Src/EGFR/PI3K/Akt/AP-1 Signaling Pathway in Human Chondrocytes by Chun-Yin Huang, Hsiu-Jung Lin, Hsin-Shui Chen, Shi-Yann Cheng, Horng-Chaung Hsu, Chih-Hsin Tang

“…Abnormalities in these processes are primary features of rheumatoid arthritis and osteoarthritis. Matrix metalloproteinase-13 (MMP-13) may contribute to the breakdown of articular cartilage during arthritis. …”
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Contraceptives or Hormone Replacement Therapy and Associations with Autoimmune Conditions: Exploring Effects of Estrogen Analog Supplementation by Irakli Tskhakaia, Yurilu Gonzalez Moret, Anna‐Kay Palmer, Diego Lema, M. Carolina Musri, Nanuka Tsibadze, Arthur Lau

“…Postmatching, significant associations persisted for most conditions, with increased risks for systemic sclerosis, systemic lupus erythematosus, giant cell arteritis, Behcet disease, psoriatic arthritis, reactive arthritis, and ankylosing spondylitis. …”
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Regional sonology of the upper limb - II: Wrist and hand by Bipin R Shah, Ankit B Shah

“…Small joints of the wrist and hand play an important role in the diagnosis and characterization of inflammatory arthritis. Successful scanning of the wrist and hand requires good scanning equipment, thorough knowledge of anatomy and scanning protocols. …”
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Certolizumab pegol in severe hidradenitis suppurativa in pregnancy: A case report by Paolo Gisondi, Elena Montalto, Tea Curic, Elisabetta Danese, Francesco Bellinato, Giampiero Girolomoni

“…Certolizumab pegol is a pegylated monoclonal TNF-α inhibitor that lacks the fragment crystallizable region preventing active placental transfer and could be used in pregnancy and lactation if clinically needed and is label for chronic plaque psoriasis, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn’s disease. …”
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Optimized methods for scRNA-seq and snRNA-seq of skeletal muscle stored in nucleic acid stabilizing preservative by Elisabeth F. Heuston, Ayo P. Doumatey, Faiza Naz, Shamima Islam, Stacie Anderson, Martha R. Kirby, Stephen Wincovitch, Stefania Dell’Orso, Charles N. Rotimi, Adebowale A. Adeyemo

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Ethnic Differences in Risk Factors for Obesity among Adults in California, the United States by Liang Wang, Jodi Southerland, Kesheng Wang, Beth A. Bailey, Arsham Alamian, Marc A. Stevens, Youfa Wang

“…Differences in risk factors for obesity were also observed: Whites (gender, age, physical activity, smoking, arthritis, and diabetes medicine intake), Latinos (age, arthritis, and diabetes medicine intake), Asians (age, binge drinking, arthritis, and diabetes medicine intake), and African Americans (gender, physical activity, smoking, binge drinking, and diabetes medicine intake). …”
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Genetic insights into the risk of hip osteoarthritis on stroke: A single-variable and multivariable Mendelian randomization. by Zhengze Zhang, Yanan Lian, Yuewen He, Hao Liu, Kai Meng, Yong Wang, Wuhua Ma

“…In Multivariable Mendelian randomization, factors such as cigarettes per day, alcoholic drinks per week, hypertension, body mass index, type 2 diabetes, C-reactive protein, rheumatoid arthritis were incorporated to further account for the independent causal effects of multiple correlated exposures.…”
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Enthesitis in a 16-Year-Old Boy with M694V Mutation by Syert Luidolf Nienhuis, Robin Eric Westerbeek

“…We would suggest treatment for enthesitis related arthritis in similar cases. This is of clinical importance because the treatment is different from treatment of enthesitis or articular pain caused by FMF.…”
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