Exploring the shared gene signatures and mechanism among three autoimmune diseases by bulk RNA sequencing integrated with single-cell RNA sequencing analysis by Xiaofang Liu, Bin Li, Yuxi Lin, Xueying Ma, Yingying Liu, Lili Ma, Xiaomeng Ma, Xia Wang, Nanjing Li, Xiaoyun Liu, Xiaohong Chen

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Genetic association between immune-mediated inflammatory diseases and peripheral artery disease: a Mendelian randomization study by Haichao Wu, Dandan Zheng, Long Zhou, Qiang Wang, Tao Wang, Siyuan Liang

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Clinical Features and Prognosis of Double-Positive Anti-MDA5 and Anti-CCP Antibodies in Dermatomyositis: A Retrospective Study by Xu X, Zhu L, Li S, Wang G, Ge Y

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Do cytokines play a role in the transition from acute to chronic musculoskeletal pain? by Andrea Ebersberger, Hans-Georg Schaible

Subjects: “…Rheumathoid arthritis…”
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Bony ankylosis adversely affects postoperative hip function in patients with ankylosing spondylitis undergoing total hip arthroplasty: a retrospective cohort study of 319 consecuti... by Liangliang Li, Jun Fu, Chi Xu, Ming Ni, Wei Chai, Libo Hao, Yonggang Zhou, Jiying Chen

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Specific immune response to M. tuberculosis and ability to in vitro control mycobacterial replication are not impaired in subjects with immune-mediated inflammatory disease and tub... by Chiara Farroni, Anna Maria Gerarda Altera, Andrea Salmi, Valentina Vanini, Valentina Vanini, Gilda Cuzzi, Cecilia S. Lindestam Arlehamn, Alessandro Sette, Giovanni Delogu, Giovanni Delogu, Ivana Palucci, Settimia Sbarra, Alessandra Aiello, Andrea Picchianti-Diamanti, Gina Gualano, Fabrizio Palmieri, Delia Goletti, Elisa Petruccioli

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Can the adherence to quality of care indicators for early rheumatoid arthritis in clinical practice reduce risk of hospitalisation?... by Carlo Alberto Scirè, Antonella Zambon, Greta Carrara, Anna Zanetti, Lisa Argnani

“…Objective To describe the adherence to quality of care indicators in early rheumatoid arthritis (RA) and to evaluate its impact on the risk of hospitalisation in a real-world setting.Design Retrospective cohort study.Setting Patients with early-onset RA identified from healthcare regional administrative databases by means of a validated algorithm between 2006 and 2012 in the Lombardy region (Italy).Participants The study cohort included 14 203 early-onset RA (71% female, mean age 60 years).Outcome measures For each patient, a summary adherence score was calculated starting from the compliance to six quality indicators: (1–2) methotrexate or sulfasalazine or leflunomide with/without glucocorticoids, (3–4) other disease-modifying antirheumatic drugs (DMARDs) with/without glucocorticoids, (5) early interruption of glucocorticoids, (6) early clinical assessment.The relationship between low, intermediate and high categories of the summary score and the 12-month risk of hospitalisation for all causes and for RA was assessed.Results During a follow-up of 1 year, 2609 hospitalisations occurred, of which 704 were for RA (main or secondary diagnosis) and 252 primarily for RA. …”
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The Pharmacodynamic Impact of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, on Circulating Levels of Inflammatory Biomarkers in Patients with Psoriatic Arthritis: Substudy Results from a Phase III, Randomized, Placebo-Controlled Trial (PALACE 1) by Peter H. Schafer, Peng Chen, Lorraine Fang, Andrew Wang, Rajesh Chopra

“…Apremilast, an oral phosphodiesterase 4 inhibitor, demonstrated effectiveness (versus placebo) for treatment of active psoriatic arthritis in the psoriatic arthritis long-term assessment of clinical efficacy (PALACE) phase III clinical trial program. …”
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The absolute number of circulating Treg cells is reduced in difficult-to-treat RA patients and is ameliorated by low-dose IL-2 by Huanhuan Yan, Huanhuan Yan, Huanhuan Yan, Xiaoyu Zi, Xiaoyu Zi, Xiaoyu Zi, Huer Yan, Xiaoying Zhang, Xiaoying Zhang, Xiaoying Zhang, Jie Bai, Jie Bai, Jie Bai, Chong Gao, Xiaofeng Li, Xiaofeng Li, Xiaofeng Li, Caihong Wang, Caihong Wang, Caihong Wang

Subjects: “…difficult-to-treat rheumatoid arthritis…”
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Biosimilars in Focus: Evaluating Their Role Compared to Adalimumab in Clinical Practice by Dorota Waz, Michał Mazur, Jakub Szarłowicz, Zofia Goliszek, Karolina Łucja Sobek, Wiktoria Tabin-Barczak, Aldona Sokołowska, Klaudia Fikas, Kamil Chwaliszewski, Sebastian Samuła

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Anxiety and depression in childhood rheumatologic conditions: A topical review by Mallet R Reid, Jacqueline Fabricius, Ashley Danguecan, Kaveh Ardalan, Andrea Knight, Natoshia R Cunningham

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Methyl Canthin-6-one-2-carboxylate Inhibits the Activation of the NLRP3 Inflammasome in Synovial Macrophages by Upregulating Nrf2 Expression by Yuanyuan Chen, Zongying Zhang, Yuan Yao, Xiaorong Zhou, Yong Ling, Liming Mao, Zhifeng Gu

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Diagnostic Algorithm for Joint Pain in Patients with Inflammatory Bowel Disorders by A. I. Dolgushina, G. M. Khusainova, O. B. Nesmeyanova, N. V. Kirsh, O. V. Solovieva, E. A. Bogdanova

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Clinical characteristics and prognosis of children with culture-negative osteoarticular infections: a meta-analysis based on cohort studies by Xingguang Chen, Jue Liu, Mingfeng Xue, Ting Zhuang, Feng Yao, Jialing Lu, Xiaodong Wang

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Effect observation and nursing of Tongbi exercise in relief of rheumatoid arthritis pain: A case report (通痹操缓解类风湿关节炎疼痛1例临床观察及护理) by YAO Jianshuang (姚建爽), TANG Ling (唐玲), WANG Huaxin (王华新), LI Suqian (李苏茜)

Subjects: “…rheumatoid arthritis…”
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Secukinumab-Induced Inflammatory Bowel Disease in a Patient Treated for Chronic Plaque Psoriasis and Psoriatic Arthritis: A Case Report and Review of the Role of Novel Biologic Agents Targeting the p19 Subunit of IL-23 by K. M. Darch, T. L. Holland, L. J. Spelman

“…Chronic plaque psoriasis and psoriatic arthritis are common autoimmune inflammatory conditions, often existing as comorbidities that have a significant impact on a patient’s quality of life. …”
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The effects of educational status and comorbidity on routine assessment of patient index data 3 and its correlation with disease activity score 28 and clinical disease activity ind... by Kubilay Sahin, Cem Ozisler, Nesibe Karahan Yesil, Fulya Dortbas, Ahmet Omma, Zeynep Ozbalkan Aslar, Yasar Karaaslan

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Fifty-Two-Week Results of Clinical and Imaging Assessments of a Patient with Rheumatoid Arthritis Complicated by Systemic Sclerosis with Interstitial Pneumonia and Type 1 Diabetes despite Multiple Disease-Modifying Antirheumatic Drug Therapy That Was Successfully Treated with Baricitinib: A Novel Case Report by Yuya Fujita, Masao Nawata, Atsushi Nagayasu, Kazuki Someya, Kazuyoshi Saito, Yoshiya Tanaka

“…Baricitinib is a Janus kinase 1/2 (JAK1/2) inhibitor used in the treatment of rheumatoid arthritis. A 71-year-old woman with rheumatoid arthritis complicated by systemic sclerosis and type 1 diabetes that were resistant to multiple disease-modifying antirheumatic drugs started treatment with baricitinib. …”
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Is Intra-articular Platelet-rich Plasma Injection Safe and Effective in Osteoarthritis Knee? A Prospective Study: A Case Series by R Sahaya Jose, N Kattu Bava, M Syed Moosa

Subjects: “…western ontario and mcmaster universities arthritis index score…”
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A meta-analysis and systematic review of the clinical efficacy and safety of platelet-rich plasma combined with hyaluronic acid (PRP + HA) versus PRP monotherapy for knee osteoarth... by Dan Du, Yuan Liang

Subjects: “…Western ontario and McMaster universities arthritis index (WOMAC) total scores…”
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