Development and Validation of an Ion-Pair HPLC-UV Method for the Quantitation of Quinoline and Indoloquinoline Alkaloids in Herbal and Pharmaceutical Antimalarial Formulations by Samuel Oppong Bekoe, Emmanuel Orman, Samuel Awenteka Adjabui, Abena Amponsaa Brobbey, James Oppong-Kyekyeku, Kwabena Frimpong-Manso Opuni, Noble Kuntworbe, Samuel Asare-Nkansah

“…Quinine- and cryptolepine-based antimalarials serve as valuable alternatives to artemisinin-based combination therapies (ACTs) in Ghana. …”
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Ceria nanoparticles ameliorate renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis by Mengling Wang, Feng Zeng, Fengling Ning, Yinhang Wang, Shilin Zhou, Jiaqi He, Cong Li, Cong Wang, Xiaolin Sun, Dongliang Zhang, Jisheng Xiao, Ping Hu, Svetlana Reilly, Hong Xin, Xudong Xu, Xuemei Zhang

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Hydrogel loaded with cerium-manganese nanoparticles and nerve growth factor enhances spinal cord injury repair by modulating immune microenvironment and promoting neuronal regenera... by Zhaoyang Gong, Zhenhao Chen, Dachuan Li, Xiao Lu, Jianwei Wu, Hanqiu Sun, Ximeng Wang, Siyang Liu, Xinlei Xia, Feizhou Lu, Jianyuan Jiang, Chi Sun, Hongli Wang, Feng Zeng, Xiaosheng Ma

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Evaluation of the protective efficacy of OlysetPlus ceiling nets for reduction of malaria incidence in children in Homa Bay County, Kenya: a cluster-randomised controlled study pro... by Daisuke Yoneoka, Jesse Gitaka, James Kongere, Wataru Kagaya, Akira Kaneko, Yura K Ko, Chim W Chan, Mariko Kanamori, Bernard N Kanoi, Gordon Odhiambo Okomo, Protus Omondi, Kelvin B Musyoka, Takatsugu Okai, Victor Opiyo, Jared Oginga, Samuel Mungai, Kibor K Keitany, Elijah Songok, Noboru Minakawa

“…In addition, the spread of Plasmodium falciparum with partial artemisinin resistance in East Africa and beyond is a great concern. …”
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Effects of plant active substances in rheumatoid arthritis—a systematic review and network meta-analysis by Qiuwei Peng, Jian Wang, Kesong Li, Congming Xia, Chuanhui Yao, Qiuyan Guo, Xun Gong, Xiaopo Tang, Quan Jiang

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Ellagic Acid from <i>Geranium thunbergii</i> and Antimalarial Activity of Korean Medicinal Plants by Hojong Jun, Joon-Hee Han, Min Hong, Fadhila Fitriana, Jadidan Hada Syahada, Wang-Jong Lee, Ernest Mazigo, Johnsy Mary Louis, Van-Truong Nguyen, Seok Ho Cha, Wanjoo Chun, Won Sun Park, Se Jin Lee, Sunghun Na, Soo-Ung Lee, Eun-Taek Han, Tae-Hyung Kwon, Jin-Hee Han

“…This study investigates the antimalarial potential of extracts and compounds from various plants used in traditional Korean medicine, in response to the increasing resistance of <i>Plasmodium falciparum</i> to standard treatments such as chloroquine and artemisinin. The antimalarial activity screening was conducted on 151 extracts, identifying the top seven candidates, including <i>Geranium thunbergii</i> (50% ethanol and 100% methanol extract), <i>Reynoutria japonica</i>, <i>Amomum villosum</i> (hot water and 50% ethanol extract), <i>Cinnamomum zeylanicum</i>, and <i>Platycodon grandiflorum</i>. …”
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Chemo-proteomics reveals dihydrocaffeic acid exhibits anti-inflammation effects via Transaldolase 1 mediated PERK-NF-κB pathway by Guanjun Li, Huiying Li, Peili Wang, Xinzhou Zhang, Wenhua Kuang, Ling Huang, Ying Zhang, Wei Xiao, Qingfeng Du, Huan Tang, Jigang Wang

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Application of a new highly multiplexed amplicon sequencing tool to evaluate Plasmodium falciparum antimalarial resistance and relatedness in individual and pooled samples from Dsc... by Jacob M. Sadler, Alfred Simkin, Valery P. K. Tchuenkam, Isabela Gerdes Gyuricza, Isabela Gerdes Gyuricza, Abebe A. Fola, Kevin Wamae, Ashenafi Assefa, Ashenafi Assefa, Karamoko Niaré, Kyaw Thwai, Samuel J. White, William J. Moss, Rhoel R. Dinglasan, Sandrine Eveline Nsango, Christopher B. Tume, Jonathan B. Parr, Jonathan B. Parr, Jonathan B. Parr, Innocent Mbulli Ali, Jeffrey A. Bailey, Jeffrey A. Bailey, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano, Jonathan J. Juliano

“…No K13 candidate or validated artemisinin partial resistance mutations were detected, but one low-level non-synonymous change was observed. …”
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Antimalarial Activity of Piperine by Artitaya Thiengsusuk, Phunuch Muhamad, Wanna Chaijaroenkul, Kesara Na-Bangchang

“…Resistance of Plasmodium falciparum to artemisinins in Southeast Asia is a great concern for disease control and research on discovery and development of new alternative antimalarial drugs is urgently required. …”
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Emerging Anthelmintic Resistance in Poultry: Can Ethnopharmacological Approaches Offer a Solution? by Zirintunda, Gerald, Biryomumaisho, Savino, Keneth Iceland, Kasozi, Batiha, Gaber El-Saber, Kateregga, John, Vudriko, Patrick, Nalule, Sarah, Olila, Deogracious, Mariam Kajoba, Mariam, Matama, Kevin, Kwizera, Mercy Rukundo, Ghoneim, Mohammed M., Abdelhamid, Mahmoud, Alshehri, Sultan, Abdelgawad, Mohamed A., Acai-Okwee, James, Zaghlool, Sameh S.

“…Flavonoids from Chenopodium album L and Mangifera indica L act through the action of phosphodiesterase and Ca2+-ATPase, and flavonoids and tannins have been shown to act synergistically and are complementary to praziquantel. Artemisinins from Artemisia cina O. Berg are known to disrupt mitochondrial ATP production. …”
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