Prostanoid Receptors in the Human Vascular Wall by Xavier Norel

“…There is an accumulation of evidence for the involvement of prostanoids, the arachidonic acid metabolites derived from the cyclooxygenase enzymatic pathway, in physiological and/or pathophysiological conditions. …”
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Mechanism of action of 5-arninosalicylic acid by N. A. Punchard, S. M. Greenfield, R. P. H. Thompson

“…Several mechanisms of action have been proposed for 5-ASA and SASP including interference in the metabolism of arachidonic acid to prostaglandins and leukotrienes, scavenging,of reactive oxygen species, effects on leucocyte function and production of cytokines. …”
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Reproductive performances of wild male tiger shrimp Penaeus monodon post-injection of oocyte developer without eyestalk ablation by Dony Prasetyo, Asda Laining, Agus Oman Sudrajat

“…Concentration of arachidonic acid in the muscle of male stock in OD1.0 group was extremely low of 0.0037% of total lipid compared to AB (0.3190%) and OD0.5 (0.2806%). …”
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12/15-Lipoxygenase Is an Interleukin-13 and Interferon-γ Counterregulated-Mediator of Allergic Airway Inflammation by Alexa R. Lindley, Margaret Crapster-Pregont, Yanjun Liu, Douglas A. Kuperman

“…Interleukin-13 increases expression of the arachidonic acid-metabolizing enzyme, 15-lipoxygenase-1, in a variety of cell types. 15-lipoxygenase-1 is dramatically elevated in the airways of subjects with asthma. …”
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Human keratinocyte sensitivity towards inflammatory cytokines varies with culture time by G. Elliott, D. van de Meent, J. van Dijk, M. Mol

“…Similar effects were observed using tumour necrosis factor-α. Both arachidonic acid (AA) and the calcium ionophore A23187 stimulated PGE2 synthesis by 7 and 14 day cultures although the increase was greatest when 7 day cultures were used. …”
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Exhaled Breath Condensate: A Promising Source for Biomarkers of Lung Disease by Yan Liang, Samantha M. Yeligar, Lou Ann S. Brown

“…Substances measured in EBC include oxidative stress and inflammatory mediators, such as arachidonic acid derivatives, reactive oxygen/nitrogen species, reduced and oxidized glutathione, and inflammatory cytokines. …”
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Nutrition and Reproductive Health: Sperm versus Erythrocyte Lipidomic Profile and ω-3 Intake by Gabriela Ruth Mendeluk, Mariano Isaac Cohen, Carla Ferreri, Chryssostomos Chatgilialoglu

“…Fatty acid analyses of sperm and erythrocyte cell membrane phospholipids in idiopathic infertile patients evidenced that erythrocyte contents of EPA, DHA, omega-6–omega-3 ratio and arachidonic acid provide a mathematical correspondence for the prediction of EPA level in sperm cells. …”
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Complex regulation of Cav2.2 N-type Ca2+ channels by Ca2+ and G-proteins. by Jessica R Thomas, Jinglang Sun, Juan De la Rosa Vazquez, Amy Lee

“…G-protein coupled receptors inhibit Cav2.2 N-type Ca2+ channels by a fast, voltage-dependent pathway mediated by Gαi/Gβγ and a slow, voltage-independent pathway mediated by Gαq-dependent reductions in phosphatidylinositol 4,5-bisphosphate (PIP2) or increases in arachidonic acid. Studies of these forms of regulation generally employ Ba2+ as the permeant ion, despite that Ca2+ -dependent pathways may impinge upon G-protein modulation. …”
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Anti-Inflammatory Effects of Epoxyeicosatrienoic Acids by Scott J. Thomson, Ara Askari, David Bishop-Bailey

“…Epoxyeicosatrienoic acids (EETs) are generated by the activity of both selective and also more general cytochrome p450 (CYP) enzymes on arachidonic acid and inactivated largely by soluble epoxide hydrolase (sEH), which converts them to their corresponding dihydroxyeicosatrienoic acids (DHETs). …”
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Perbandingan Jumlah Trombosit pada Pasien COVID-19 dengan Kadar Glukosa yang Berbeda by Imanta Alifia Octavira, Agrijanti Agrijanti, Lalu Srigede, Siti Zaetun

“…Hyperglycemia has increased arachidonic acid thromboxane which is an effective ingredient in platelet activation. …”
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Molecular Circuits of Resolution in the Eye by Elvira L. Liclican, Karsten Gronert

“…Eicosanoids derived from ω-6 arachidonic acid (AA) have long been recognized for their roles in cardiovascular and renal functions, and vascular tone, as well as regulating inflammatory and immune functions. …”
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Marine Diterpenoids as Potential Anti-Inflammatory Agents by Yisett González, Daniel Torres-Mendoza, Gillian E. Jones, Patricia L. Fernandez

“…The anti-inflammatory activity of marine diterpenoids has been attributed to the inhibition of Nuclear Factor-κB activation and to the modulation of arachidonic acid metabolism. However, more research is necessary to describe the mechanisms of action of these secondary metabolites. …”
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Mechanism of Cytosolic Phospholipase A2 Activation in Ghrelin Protection of Salivary Gland Acinar Cells against Ethanol Cytotoxicity by Bronislaw L. Slomiany, Amalia Slomiany

“…The protective effect of ghrelin was associated with the increase in NO and PGE2, and upregulation in cytosolic phospholipase A2 (cPLA2) activity and arachidonic acid (AA) release. The loss in countering effect of ghrelin occurred with cNOS inhibitor, L-NAME, as well as indomethacin and COX-1 inhibitor, SC-560, while COX-2 inhibitor, NS-398, and iNOS inhibitor, 1400W, had no effect. …”
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Relationship between Fecal Content of Fatty Acids and Cyclooxygenase mRNA Expression and Fatty Acid Composition in Duodenal Biopsies, Serum Lipoproteins, and Dietary Fat in Colecto... by K. Almendingen, A. T. Høstmark, L. N. Larsen, O. Fausa, J. Bratlie, L. Aabakken

“…In the ileostomy group separately (n=12), the fecal content of arachidonic acid was correlated negatively to the proportions of eicosapentaenoic acid and docosahexaenoic acid in duodenal biopsies. …”
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Effects of the Maximum Recommended Levels of Fumonisins in the EU on Oxylipin Profiles in the Liver and Brain of Chickens by Philippe Guerre, Elodie Lassallette, Amélie Guerre, Didier Tardieu

“…By nine days, several OLs derived from arachidonic acid, spanning all enzymatic pathways, became discriminative. …”
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Dietary (n-6 : n-3) Fatty Acids Alter Plasma and Tissue Fatty Acid Composition in Pregnant Sprague Dawley Rats by Amira Abdulbari Kassem, Md Zuki Abu Bakar, Goh Yong Meng, Noordin Mohamed Mustapha

“…The total n-6 PUFA, linoleic acid, and arachidonic acid were significantly difference in Diet 30 : 1 as compared to Diet 1 : 1 and control group. …”
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Investigation of Growth Performance, Proximate and Fatty Acid Composition of Freshwater (Euglena gracilis, Chlorella vulgaris) and Marine (Pavlova lutheri, Diacronema vlkanium) Mic... by Kamil Mert Eryalçın, Merve Sayar

“…The highest EPA (C20:5n-3) content was found in Pavlova lutheri (6.85%) whereas arachidonic acid (C20:4n-6) and docosahexaenoic acid (C22:6n-3) contents were only found with a level of (3.32%) and (1.79%) in Euglena gracilis, respectively. …”
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Brain-Specific Increase in Leukotriene Signaling Accompanies Chronic Neuroinflammation and Cognitive Impairment in a Model of Gulf War Illness by Sahithi Attaluri, Raghavendra Upadhya, Maheedhar Kodali, Leelavathi N. Madhu, Dinesh Upadhya, Bing Shuai, Ashok K. Shetty

“…Studies in a mouse model of GWI have also shown upregulation of several phospholipids that serve as reservoirs of arachidonic acid, a precursor of leukotrienes (LTs). However, it is unknown whether altered LT signaling is a component of chronic neuroinflammatory conditions in GWI. …”
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Fatty Acids in Cnidaria: Distribution and Specific Functions by Vasily I. Svetashev

“…Many of the families have characteristic FAs: Acroporidae are characterized by 18:3n6, eicosapentaenoic acid (EPA) 20:5n3, 22:4n6, and 22:5n3; Pocilloporidae by 20:3n6, 20:4n3, and docosahexaenoic acid 22:6n3 (DHA); and Poritidae by arachidonic acid (AA) and DHA. The species of Faviidae show elevated concentrations of 18:3n6 and 22:5n3 acids. …”
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Nutritional profiling of breast muscle: A comparative study between Yuzhong pigeons and European meat pigeons by Pengkun Yang, Xinghui Song, Wenyi Wu, Liheng Zhang, Zhanbing Han, Xinlei Wang, Runzhi Wang, Mingjun Yang, Zhen Zhang

“…In contrast, European meat pigeons were richer in polyunsaturated fatty acids, such as linoleic acid, arachidonic acid, and DHA. These results highlight nutritional distinctions between the breeds, providing guidance for breeding programs and offering insights for consumers seeking specific dietary attributes in poultry meat.…”
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