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DeepAptamer: Advancing high-affinity aptamer discovery with a hybrid deep learning model
Published 2025-03-01Subjects: Get full text
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Cell-Specific Aptamers as Emerging Therapeutics
Published 2011-01-01“…Aptamers are short nucleic acids that bind to defined targets with high affinity and specificity. …”
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Structure-based insights into fluorogenic RNA aptamers
Published 2024-08-01Subjects: “…fluorogenic RNA aptamers…”
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Aptamers: A Feasible Technology in Cancer Immunotherapy
Published 2016-01-01“…Aptamers normally show affinities comparable to or higher than that of antibodies. …”
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Peptide Aptamer–Paclitaxel Conjugates for Tumor Targeted Therapy
Published 2024-12-01Subjects: Get full text
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Capture-SELEX: Selection of DNA Aptamers for Aminoglycoside Antibiotics
Published 2012-01-01“…Often they are not suitable for immobilization on solid surfaces, which is a common procedure in known aptamer selection methods. The Capture-SELEX procedure allows the selection of DNA aptamers for solute targets. …”
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7
Selective and Sensitive Fluorescence Aptamer Biosensors of Adenosine Triphosphate
Published 2016-05-01Subjects: Get full text
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8
Molecular Programming Design of Glyconucleic Acid Aptamer with High Stability
Published 2025-01-01Subjects: “…aptamers…”
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Machine learning-powered, high-affinity modification strategies for aptamers
Published 2025-01-01“…The binding affinity of aptamers to targets has a crucial role in the pharmaceutical and biosensing effects. …”
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Microarrays as Model Biosensor Platforms to Investigate the Structure and Affinity of Aptamers
Published 2016-01-01“…Immobilization of nucleic acid aptamer recognition elements selected free in solution onto the surface of biosensor platforms has proven challenging. …”
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Nucleic-Acid-Binding Chromophores as Efficient Indicators of Aptamer-Target Interactions
Published 2012-01-01“…The binding affinity and specificity of nucleic acid aptamers have made them valuable candidates for use as sensors in diagnostic applications. …”
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Single-Round Patterned DNA Library Microarray Aptamer Lead Identification
Published 2015-01-01“…A method for identifying an aptamer in a single round was developed using custom DNA microarrays containing computationally derived patterned libraries incorporating no information on the sequences of previously reported thrombin binding aptamers. …”
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Method to Determine the Optimal Aptamer-to-Bead Ratio by Using Flow Cytometry
Published 2023-01-01“…Research on the effective attachment of aptamers to beads, which is essential for using aptamers, has made relatively little progress. …”
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Kloramfenikol Aptameri Fonksiyonlandırılmış DNA Hidrojellerinin Sentez Koşullarının Optimizasyonu
Published 2023-03-01Subjects: “…aptamer…”
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Sensitivity and Selectivity on Aptamer-Based Assay: The Determination of Tetracycline Residue in Bovine Milk
Published 2012-01-01“…A competitive enzyme-linked aptamer assay (ELAA) to detect tetracycline in milk was performed by using two different aptamers individually; one is 76 mer-DNA aptamer and the other is 57 mer-RNA aptamer. …”
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Research Progress in Small-Molecule Detection Using Aptamer-Based SERS Techniques
Published 2025-01-01Subjects: Get full text
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Investigation on small molecule-aptamer dissociation equilibria based on antisense displacement probe
Published 2023-07-01Subjects: “…Aptamer…”
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Preparation of a Specific ssDNA Aptamer for Brevetoxin-2 Using SELEX
Published 2016-01-01“…This paper reports the use of aptamers binding to BTX-2 in an analytical assay using the systematic evolution of ligands by exponential enrichment (SELEX). …”
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Aptamers as new promising entities for therapeutics: our experience from the neurological diseases
Published 2025-12-01Get full text
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20
Serum assisted PD-L1 aptamer screening for improving its stability
Published 2025-01-01Subjects: Get full text
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