Showing 241 - 260 results of 2,079 for search '"apoptosis"', query time: 0.06s Refine Results
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    Protein Kinase A Is Involved in Neuropathic Pain by Activating the p38MAPK Pathway to Mediate Spinal Cord Cell Apoptosis by Yajun Deng, Liang Yang, Qiqi Xie, Fengbiao Yang, Guoqiang Li, Guangzhi Zhang, Shaoping Li, Zuolong Wu, Jing Wang, Xuewen Kang

    Published 2020-01-01
    “…However, intrathecal injection of a p38MAPK inhibitor attenuated mechanical hyperalgesia, inflammation, and apoptosis, but did not affect PKA expression. In conclusion, PKA is involved in neuropathic pain by activating the p38MAPK pathway to mediate spinal cord cell apoptosis.…”
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    Cannabidiol attenuates lipid metabolism and induces CB1 receptor-mediated ER stress associated apoptosis in ovarian cancer cells by Xuanhe Fu, Zhixiong Yu, Fang Fang, Weiping Zhou, Yuxin Bai, Zhongjia Jiang, Biao Yang, Ye Sun, Xing Tian, Guangyan Liu

    Published 2025-02-01
    “…Taken collectively, these data indicate that CBD may disrupt lipid metabolism, and lead to ER stress-related apoptosis in OCs. Our findings may provide a theoretical mechanism for anti-ovarian cancer using CBD.…”
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    Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy by Wenwen Wang, Liwei Wu, Jingjing Li, Jie Ji, Kan Chen, Qiang Yu, Sainan Li, Jiao Feng, Tong Liu, Jie Zhang, Jiaojiao Chen, Yuting Zhou, Yuqing Mao, Fan Wang, Weiqi Dai, Xiaoming Fan, Chuanyong Guo, Jianye Wu

    Published 2019-01-01
    “…OA upregulated Bcl-2 and downregulated caspase-3, caspase-9, Bax, Beclin 1, and LC3, which play crucial roles in the regulation of apoptosis and autophagy. These findings highlighted the protective effects of OA against hepatic IRI mediated by the inhibition of apoptosis and autophagy and the release of HMGB1, which acted as a late inflammatory mediator in hepatic IRI.…”
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    Inverse Agonist of Retinoid-Related Orphan Receptor-Alpha Prevents Apoptosis and Degeneration in Nucleus Pulposus Cells via Upregulation of YAP by Tongzhou Liang, Jincheng Qiu, Shaoguang Li, Zhihuai Deng, Xianjian Qiu, Wenjun Hu, Pengfei Li, Taiqiu Chen, Zhancheng Liang, Hang Zhou, Bo Gao, Dongsheng Huang, Anjing Liang, Wenjie Gao

    Published 2021-01-01
    “…The elevation of RORα is associated with increased apoptosis of nucleus pulposus (NP) cells. Therefore, we applicated a well-established inverse agonist of RORα, SR3335, to investigate its role in regulating NP cell metabolism and apoptosis. …”
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    Tumor Necrosis Factor (TNF) Receptor Expression Determines Keratinocyte Fate upon Stimulation with TNF-Like Weak Inducer of Apoptosis by Xuening Wang, Dan Cheng, Guanglei Hu, Lili Liang, Fei Tan, Tong Xiao, Shengxiang Xiao, Yumin Xia

    Published 2019-01-01
    “…The interaction between tumor necrosis factor- (TNF-) like weak inducer of apoptosis (TWEAK) and fibroblast growth factor-inducible 14 (Fn14) regulates the fate of keratinocytes, depending on the relative expression of TNF receptor (TNFR) 1 or TNFR2. …”
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