Clinical Predictors of Hospital-acquired Pneumonia Associated with Acute Ischemic by Alexis Suárez Quesada, Ezequiel López Espinosa, Noelsis García Verdecia, Miguel Ángel Serra Valdés

“…The following independent factors were identified: Glasgow Coma Scale ≤ 11 (OR: 26.099; 95 % CI 7.164-85.075), history of chronic obstructive pulmonary disease (OR: 8.896; 95 % CI 1.203-65.779), dysphagia (OR: 7.652; 95 % CI 2.369- 24.720), history of heart failure (OR: 4.583; 95 % CI 1.240- 16.932) and dysarthria/severe motor aphasia (OR: 4.222; 95 % CI 1.374- 12.975). <strong><br />Conclusions:</strong> the resulting logistic regression model is valid for predicting post-stroke pneumonia based on data routinely acquired.…”
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Cerebellar Cathodal Transcranial Direct Stimulation and Performance on a Verb Generation Task: A Replication Study by K. Spielmann, R. van der Vliet, W. M. E. van de Sandt-Koenderman, M. A. Frens, G. M. Ribbers, R. W. Selles, S. van Vugt, J. N. van der Geest, P. Holland

“…These findings suggest a potential negative effect of c-tDCS and warrant further investigation into long term effects of c-tDCS before undertaking clinical studies with poststroke patients with aphasia.…”
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Linguistic means of creating an image of a person with intellectual disabilities in D. Keyes’s novel «Flowers for Algernon» by Olga Kanevska, Iryna Klymenko

“…Reproducing the speech portrait of a character in the text of a literary work is a difficult artistic task, especially for characters who have certain intellectual impairments and speech disorders, i.e. suffer from aphasia. The writer gives an authentic and detailed description of certain manifestations of aphatic syndromes in the character taking into account both language disorders and psychopathological manifestations that significantly affect the structure and content of the text. …”
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Syntactic Comprehension in Patients with Amyotrophic Lateral Sclerosis by Kentarou Yoshizawa, Nao Yasuda, Michinari Fukuda, Yumi Yukimoto, Mieko Ogino, Wakana Hata, Ikuyo Ishizaka, Mari Higashikawa

“…In this study, we evaluated syntactic comprehension using the Syntax Test for Aphasia (STA) auditory comprehension task, frontal executive function using the Frontal Assessment Battery (FAB), visuospatial function using Raven’s Coloured Progressive Matrices (RCPM), and dementia using the Hasegawa Dementia Scale-Revised (HDS-R) in 25 patients with ALS. …”
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Nonfluent/Agrammatic PPA with In-Vivo Cortical Amyloidosis and Pick’s Disease Pathology by Francesca Caso, Benno Gesierich, Maya Henry, Manu Sidhu, Amanda LaMarre, Miranda Babiak, Bruce L. Miller, Gil D. Rabinovici, Eric J. Huang, Giuseppe Magnani, Massimo Filippi, Giancarlo Comi, William W. Seeley, Maria Luisa Gorno-Tempini

“…We present comprehensive, prospective longitudinal data for a 66 year old, right-handed female who met current criteria for the nonfluent/agrammatic variant of primary progressive aphasia (nfvPPA). She first presented with a 3-year history of progressive speech and language impairment mainly characterized by severe apraxia of speech. …”
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A Pilot Study on Cognitive Processing Characteristics and Cerebral Mechanisms of Native Chinese-Speaking Savant Calendar Calculators with Autism Spectrum Disorder by CHEN Jian, XU Shutian, WU Yuwei, CHEN Songmei, SHAN Chunlei

“…The correct rate of subtraction and multiplication was 93.8%, and the average time was 23.51 s and 34.88 s, respectively. (4) JLO test: the score of JLO test in the SCC patient was 27. (5) Examination of apraxia: the patient showed partial orofacial apraxia and no speech apraxia, but the patient had ideomotor aphasia (score=32). (6) Scores of FAB and MoCA: the FAB score of the patient was 13, and mainly indicated impairment in similarity test and verbal fluency. …”
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Prevalence of delirium in German nursing homes: protocol for a cross-sectional study by Bernhard Holle, Romy Lauer, Horst Christian Vollmar, Petra Thürmann, Rebecca Palm, Jonas Dörner, Alexandre Houdelet-Oertel, Zafer Arslan, Ina Otte

“…The exclusion criteria are aphasia, coma, deafness or end-of-life status. The 4 ‘A’s Test will be used as the primary measurement. …”
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Research investigating patient and carer psychoeducation needs regarding post-stroke cognition: a scoping review by Nele Demeyere, Georgina Hobden, Faye Tabone

“…Most articles focused on aphasia with very few studies considering other cognitive domains (eg, memory, attention, executive function).Conclusions The need for psychoeducation regarding cognition is well evidenced throughout the post-stroke care continuum, though most research has focused on language impairments. …”
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Complex and severe infection in a 67-year-old liver transplant recipient due to Cunninghamella elegans, Bordetella bronchiseptica, and Pneumocystis jirovecii by Muyun Wei, Kangyi Gu, Juanxiu Qin, Xinhua Lu, Junqi Feng, Shaowei Mao, Min Li, Zhilan Li, Changsheng Wang

“…During the treatment process, we also observed rare and unusual neurological side effects: visual and auditory hallucinations, restlessness, and aphasia. Also, the case indicates that traditional methods are insufficient for the etiological diagnosis needs of critical and severe patient populations, and timely use of mNGS should be recommended.…”
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Case report: A rare case of a long-term survivor of glioblastoma who underwent two courses of hypofractionated radiotherapy as part of her care by Midhad Mrvoljak, Midhad Mrvoljak, Shubhendu Mishra, Liam Chen, Liam Chen, Elizabeth Neil, Elizabeth Neil, Eric Ehler, Stephanie Terezakis, Stephanie Terezakis, Lindsey Sloan, Lindsey Sloan

“…The patient is a 75-year-old woman who presented with progressive aphasia and was diagnosed with GB (WHO grade 4, IDH1/IDH2 wild type, ATRX intact, p53 and PTEN mutant, BRAF non-mutated, O6-methylguanine-DNA methyltransferase promoter methylated) and who underwent surgical resection, hypofractionated radiotherapy (HFRT) using intensity-modulated radiotherapy (IMRT) (4,005 cGy in 15 fractions) alone, and adjuvant temozolomide (TMZ). …”
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A variant in GRN of Spanish origin presenting with heterogeneous phenotypes by M. Menéndez-González, A. García-Martínez, I. Fernández-Vega, A. Pitiot, V. Álvarez

“…Results: Phenotypes were strikingly different, including cases presenting with behavioral variant frontotemporal dementia, semantic variant primary progressive aphasia, rapidly progressive motor neuron disease (pathologically documented), and tremor-dominant parkinsonism. …”
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A variant in GRN of Spanish origin presenting with heterogeneous phenotypes by M. Menéndez-González, A. García-Martínez, I. Fernández-Vega, A. Pitiot, V. Álvarez

“…Results: Phenotypes were strikingly different, including cases presenting with behavioral variant frontotemporal dementia, semantic variant primary progressive aphasia, rapidly progressive motor neuron disease (pathologically documented), and tremor-dominant parkinsonism. …”
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Progressively complex neurorehabilitation: from a severe coma to a vegetative state, minimal consciousness ... and the Phoenix bird survives and is reborn from its ashes by Andreea-Iulia Vlădulescu-Trandafir, Aurelian Anghelescu, Ana-Andreea Cristea, Gelu Onose

“…In time, he progressed to a minimally conscious state; he responded to verbal stimuli through blinking and reactive adequate affective mimic in the context of persistent expressive aphasia. He was safely discharged at home. Our main functional objective is the patient’s reinsertion into his family. …”
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Neuropsychiatric manifestations following chimeric antigen receptor T cell therapy for cancer: a systematic review of clinical outcomes and management strategies by Max Topp, Michael Hudecek, Hermann Einsele, Imad Maatouk, Leo Rasche, Johannes Duell, Anna Fleischer, Sophia Kurth, Patrick-Pascal Strunz, Julia Mersi, Carmen Sanges

“…Among the most frequently reported neuropsychological symptoms were aphasia, attention deficits, impaired consciousness, and disorientation, alongside a constellation of other symptoms including confusion, cognitive impairment, memory loss, writing difficulties, fatigue, headache, agitation, tremor, seizures, and psychomotor retardation. …”
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Heterogeneous clinical phenotypes of sporadic early-onset Alzheimer’s disease: a neuropsychological data-driven approach by Deepti Putcha, Yuta Katsumi, Alexandra Touroutoglou, Ani Eloyan, Alexander Taurone, Maryanne Thangarajah, Paul Aisen, Jeffrey L. Dage, Tatiana Foroud, Clifford R. Jack, Joel H. Kramer, Kelly N. H. Nudelman, Rema Raman, Prashanthi Vemuri, Alireza Atri, Gregory S. Day, Ranjan Duara, Neill R. Graff-Radford, Ian M. Grant, Lawrence S. Honig, Erik C. B. Johnson, David T. Jones, Joseph C. Masdeu, Mario F. Mendez, Erik Musiek, Chiadi U. Onyike, Meghan Riddle, Emily Rogalski, Stephen Salloway, Sharon Sha, R. Scott Turner, Thomas S. Wingo, David A. Wolk, Kyle Womack, Maria C. Carrillo, Gil D. Rabinovici, Bradford C. Dickerson, Liana G. Apostolova, Dustin B. Hammers, the LEADS Consortium

“…In contrast to the heterogeneity observed from our neuropsychological data-driven approach, diagnostic classifications for this same sample based solely on clinical judgment indicated that 82% of individuals were amnestic-predominant, 9% were non-amnestic, 4% met criteria for Posterior Cortical Atrophy, and 5% met criteria for Primary Progressive Aphasia. Conclusion A neuropsychological data-driven method to phenotype EOAD individuals uncovered a more detailed understanding of the presenting heterogeneity in this atypical AD sample compared to clinical judgment alone. …”
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Cortical Lewy Body Dementia by W. R. G. Gibb

“…The age of onset reflects that of Parkinson's disease, and clinical features, though not diagnostic, include aphasias, apraxias, agnosias, paranoid delusions and visual hallucinations. …”
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Relapsing Depression in Paramedian Thalamic Infarctions by R. W. Baumgartner, T. Landis, M. Regard

“…Thalamic infarctions have been shown to mimic a variety of higher functional deficits, such as aphasias, apraxias and attentional disorders, traditionally associated with hemispheric strokes. …”
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Addressing inter individual variability in CSF levels of brain derived proteins across neurodegenerative diseases by Sára Mravinacová, Sofia Bergström, Jennie Olofsson, Nerea Gómez de San José, Sarah Anderl-Straub, Janine Diehl-Schmid, Klaus Fassbender, Klaus Fliessbach, Holger Jahn, Johannes Kornhuber, G. Bernhard Landwehrmeyer, Martin Lauer, Johannes Levin, Albert C. Ludolph, Johannes Prudlo, Anja Schneider, Matthias L. Schroeter, Jens Wiltfang, Petra Steinacker, FTLD Consortium, Markus Otto, Peter Nilsson, Anna Månberg

“…Here, we measured the levels of 69 pre-selected proteins in cerebrospinal fluid using antibody-based suspension bead array technology in a multi-disease cohort of 499 individuals with neurodegenerative disorders including Alzheimer’s disease (AD), behavioral variant frontotemporal dementia, primary progressive aphasias, amyotrophic lateral sclerosis (ALS), corticobasal syndrome, primary supranuclear palsy, along with healthy controls. …”
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