Lineage tracing studies suggest that the placenta is not a de novo source of hematopoietic stem cells. by Xiaowen Chen, Joanna Tober, Martin Dominguez, Alan T Tang, Jenna Bockman, Jisheng Yang, Sneha Mani, Chin Nien Lee, Mei Chen, Triloshan Thillaikumaran, Patricia Mericko-Ishizuka, Monica Mainigi, Nancy A Speck, Mark L Kahn

“…However, during human gestation HSPCs arise in the aorta considerably earlier than when they can first be detected in the placenta, suggesting that the placenta may primarily serve as a niche. …”
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Anomalous Coronary Artery Origin in a Young Patient with Marfan Syndrome by S. B. C. P. Duarte, D. O. Beraldo, L. A. M. Cesar, A. P. Mansur, J. Y. Takada

“…Aortic aneurysm is its main complication, and along the dilation of the aorta root and its descending portion (60–100%), with secondary aortic insufficiency, it increases risk of acute aortic dissection and death. …”
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Toll-Like Receptor-4 Mediated Inflammation Is Involved in the Cardiometabolic Alterations Induced by Intermittent Hypoxia by Laureline Poulain, Vincent Richard, Patrick Lévy, Maurice Dematteis, Claire Arnaud

“…Animals were assessed at 1-week exposure for insulin tolerance test and after 4-week exposure for morphological and inflammatory changes of the epididymal fat and thoracic aorta. Results. IH induced insulin resistance, morphological and inflammatory changes of the epididymal fat (smaller pads and adipocytes, higher release of TNF-α and IL-6) and aorta (larger intima-media thickness and higher NFκB-p50 activity). …”
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Chest Pain: The Need to Consider Less Frequent Diagnosis by Pedro Magalhães, Anabela Morais, Sofia Carvalho, Joana Cunha, Ana R. Lima, J. Ilídio Moreira, Trigo Faria

“…Chest pain is experienced by >40% of the patients and results from the inflammation of the aorta, pulmonary artery, or coronaries.…”
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Posterior Nutcracker Syndrome with Left Renal Vein Duplication: A Rare Cause of Haematuria in a 12-Year-Old Boy by J. Preza Fernandes, Rui Amorim, M. J. Gomes, V. Oliveira, A. Reis, J. Ribeiro-Castro

“…The Doppler ultrasonography showed turbulent pattern of venous blood flow of the posterior renal vein branch behind the aorta. The abdominopelvic computer tomography (apCT) revealed left renal vein (LRV) duplication with a dilated retroaortic branch, entrapped between the aorta and the vertebral column, promoting the renal nutcracker syndrome. …”
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Impact of Notch3 Activation on Aortic Aneurysm Development in Marfan Syndrome by Kathryn Jespersen, Chenxin Li, Rishi Batra, Christopher A. Stephenson, Paul Harding, Kylie Sestak, Ryan T. Foley, Harrison Greene, Trevor Meisinger, Jason R. Cook, B. Timothy Baxter, Wanfen Xiong

“…DAPT treatment reduced elastin fiber fragmentation in the aorta and reversed the differentiation of SMCs. Conclusions. …”
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Mouse Mesenchymal Progenitor Cells Expressing Adipogenic and Osteogenic Transcription Factors Suppress the Macrophage Inflammatory Response by Natalie Fernandez, Heather Renna, Lauren McHugh, Katie Mazolkova, William Crugnola, Jodi F. Evans

“…Conversely, mesenchymal progenitors from the mouse aorta (mAo) support and contribute to the MΦ response under inflammatory conditions. …”
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Ex vivo validation of magnetically actuated intravascular untethered robots in a clinical setting by Leendert-Jan W. Ligtenberg, Nicole C. A. Rabou, Constantinos Goulas, Wytze C. Duinmeijer, Frank R. Halfwerk, Jutta Arens, Roger Lomme, Veronika Magdanz, Anke Klingner, Emily A. M. Klein Rot, Colin H. E. Nijland, Dorothee Wasserberg, H. Remco Liefers, Pascal Jonkheijm, Arturo Susarrey-Arce, Michiel Warlé, Islam S. M. Khalil

“…The untethered magnetic robots effectively demonstrate locomotion in a difficult-to-access target site, navigating through the abdominal aorta and reaching the distal end of the renal artery.…”
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Dapagliflozin inhibits ferroptosis to improve chronic heart failure by regulating Nrf2/HO-1/GPX4 signaling pathway. by Jing Zhang, Xuefeng Chen, Shilin Lv, Qingqing Hao

“…<h4>Methods</h4>Nine healthy adult male New Zealand white rabbits were randomly divided into Sham group (only thorax opening was performed in Sham group, no ascending aorta circumferential ligation was performed), Heart failure group (HF group, ascending aorta circumferential ligation was performed in HF group to establish the animal model of heart failure), and Dapagliflozin group (DAPA group, after the rabbit chronic heart failure model was successfully made in DAPA group). …”
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Neutrophil membrane biomimetic delivery system (Ptdser‐NM‐Lipo/Fer‐1) designed for targeting atherosclerosis therapy by Wei Li, Chang Liu, Sichuan Wang, Naifeng Liu

“…Meanwhile, due to the modification of the Ptdser, the aorta in Ptdser‐NM‐Lipo/Fer‐1‐treated mice exhibited the highest fluorescence intensity, demonstrating its excellent targeting ability for atherosclerosis. …”
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QUANTIFICATION OF ECTOPIC FAT DEPOTS IN PATIENTS WITH CORONARY HEART DISEASE by A. N. Kokov, N. K. Brel, V. L. Masenko, O. V. Gruzdeva, Yu. A. Dyleva, E. V. Belik, O. L. Barbarash

“…In order to visualize and morphometry pericoronary and paraaortic adipose tissue at the level of the thoracic aorta, patients in both groups were performed MSCT angiography of the coronary arteries with ECG synchronization. …”
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Coexistence of Rheumatoid Arthritis, Systemic Lupus Erythematosus, Sjogren Syndrome, Antiphospholipid Syndrome, and Ankylosing Spondylitis by Moshiur Rahman Khasru, Md Abu Bakar Siddiq, Kazi Mohammad Sayeeduzzaman, Tangila Marzen, Abul Khair Mohammad Salek

“…There was radiological cardiomegaly, echocardiography unveiled atrial regurgitation, and ascending aorta aneurysm. Based on the abovementioned information, RA, AS, and systemic lupus erythematosus (SLE) have been diagnosed. …”
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Phenotypic and Functional Changes of Endothelial and Smooth Muscle Cells in Thoracic Aortic Aneurysms by Anna Malashicheva, Daria Kostina, Aleksandra Kostina, Olga Irtyuga, Irina Voronkina, Larisa Smagina, Elena Ignatieva, Natalia Gavriliuk, Vladimir Uspensky, Olga Moiseeva, Jarle Vaage, Anna Kostareva

“…The purpose of the present work was to study the cellular functions of endothelial and smooth muscle cells from the patients with aneurysms of the thoracic aorta. We studied endothelial and smooth muscle cells from aneurysms in patients with bicuspid aortic valve and with tricuspid aortic valve. …”
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Application of three-dimensional printing in the planning and execution of aortic aneurysm repair by Harshank Patel, Paul Choi, Jennifer C. Ku, Rosemary Vergara, Rafael Malgor, Dhiren Patel, Yong Li

“…This review examines the application of 3D printing and AI in complex aortic aneurysm repair, highlighting current clinical trends.MethodsAn exhaustive literature review was performed using keywords such as “3D printing,” “Artificial intelligence,” “Thoracoabdominal aneurysm,” “Abdominal aortic aneurysm,” “Aortic arch aneurysm,” “Endovascular repair,” and “Open repair” in PubMed and Google Scholar indexes up to June 2022.ResultsThis analysis included seven studies: four focused on 3D-printed phantoms for endovascular repair of various aortic pathologies (aortic arch, thoracoabdominal aorta, juxtarenal and pararenal aorta), one on open thoracoabdominal aneurysm repair using 3D-printed models for graft construction, and two on the use of convolutional neural networks, an AI-based technology, for the pre-processing of aortic computed tomography angiography images.ConclusionThe application of 3D printing and AI-based image pre-processing in the planning of complex aortic aneurysms offers several benefits, including enhanced patient and trainee education, more accurate fenestration placement, reduced surgical time and complications, and decreased surgeon stress.…”
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Biomarkers to predict the outcomes of surgical intervention for aortic dissection by Abanob G. Hanna, Fabian Jimenez Contreras, Omar M. Sharaf, Griffin P. Stinson, Philip J. Hess

“…The aim of this review is to summarize the literature concerning the prognostic ability of various preoperative biomarkers for patients undergoing surgical repair of the thoracic and abdominal aorta to elucidate whether these biomarkers could improve the selection of surgical candidates. …”
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Multi-layered electrospun grafts for surgical repair: Biomimicking physiological ascending aortic compliance by Julia Krammer, Maximilian Pichlmaier, Jan Stana, Christian Hagl, Sven Peterss, Maximilian Grab, Linda Grefen

“…Despite durable and biocompatible, these grafts do not reproduce the natural mechanical properties of the aorta. Therefore, the aim of this project was to develop an innovative graft that additionally exhibits physiological aortic compliance. …”
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Vertebral Erosion Secondary to Aortic Aneurysm by Zakaria Toufga, Fadma Aoujil, Nabil Moatassim Billah, Ittimad Nassar

“…The aneurysm of the thoracic aorta compresses the anterior surface of the dorsal vertebrae and by mechanical effect is responsible for the destruction of the opposite bone. …”
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Interrupted Aortic Arch Complicated with Type A Aortic Dissection in a Young Adult by Ashish Dua, Arun Sharma, Rupesh Kumar, Manphool Singhal

“…Interrupted aortic arch (IAA) is a congenital anomaly characterized by a discontinuity between the ascending and descending aorta. We present a 27-year-old male patient who had presented with Stanford Type A aortic dissection and was subsequently found to have IAA on computed tomography aortogram. …”
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Visceral Adipose Tissue Inflammation and Vascular Complications in a Rat Model with Severe Dyslipidemia: Sex Differences and PAI-1 Tissue Involvement by Irena Markova, Martina Hüttl, Natalie Gayova, Denisa Miklankova, Kristyna Cerna, Martina Kavanova, Petra Skaroupkova, Sona Cacanyiova, Hana Malinska

“…However, HHTg females had lower tumor necrosis factor alpha (TNFα) gene expression in the aorta. Severe dyslipidemia in this prediabetic model was associated with hypercoagulation and low-grade chronic inflammation. …”
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Cervical heterotopic heart transplantation in mice using a novel suture technique by Hao Dun, MD MSc, Maura Sticco-Ivins, Yuriko Terada, MD PhD, Amber Berning, MD, Kory J. Lavine, MD PhD, Daniel Kreisel, MD PhD, Benjamin J. Kopecky, MD PhD

“…Finally, the donor ascending aorta is end-to-side anastomosed to the recipient common carotid artery with an identical suture technique. …”
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