Efficacy of Lurasidone in First-Episode Psychosis: Patient Phenotypes, Dosage, and Recommendations from an Expert Panel by Miquel Bernardo, Marina Díaz Marsá, Ana González-Pinto, Manuel Martín Carrasco, Víctor Pérez Sola, Pilar Alejandra Sáiz, Eduard Vieta, Marta Torrens, Celso Arango, Benedicto Crespo-Facorro

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Usage and cost-effectiveness of anti-psychotics in psychiatry OPD among various clinical conditions: A prospective observational study in a tertiary care center by Reshabh Saini, Chandrasekaran Dhinakaran, Rohit Raina, Ramanathan Gandhibabu, Kathiresan Krishnasamy

Subjects: “…antipsychotics…”
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Antipsychotic Drugs Reverse MK801-Inhibited Cell Migration and F-actin Condensation by Modulating the Rho Signaling Pathway in B35 Cells by Yi-Chyan Chen, Fu-Ming Tsai, Mao-Liang Chen

“…MK801-induced psychotic symptoms and also the Ras homolog family member A (RhoA) expression and cell division control protein 42 (cdc42) mRNA modulation in the rat brain have been investigated. Antipsychotic drugs (APDs) have been reported to induce Rho GDP-dissociation inhibitor (RhoGDI) pathway regulation related to cytoskeleton reorganization in neuronal cells. …”
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Muscarinic receptor agonists and positive allosteric modulators in animal models of psychosis: protocol for a systematic review and meta-analysis [version 2; peer review: 1 approve... by Spyridon Siafis, Johannes Schneider-Thoma, Alexandra Bannach-Brown, Oliver D. Howes, Virginia Chiocchia, Ulf Tölch, Natascha I. Drude, Sabine M. Hölter, Andrea de Bartolomeis, Anthony C. Vernon, Georgia Salanti, Sridhar Natesan, Stefan Leucht, Irene Bighelli, Sameer Jauhar, Ioannis Mantas, Josef Priller, Francesca Tinsdeall, Wulf-Peter Hansen, Fiona J. Ramage, Nobuyuki Nomura, Malcolm R. Macleod

Subjects: “…antipsychotic; schizophrenia; psychosis; muscarinic receptor; acetylcholine; meta-analysis…”
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Quetiapine-related weight loss: Report of a rare adverse effect by Nicodemus Okwudili K Obayi, David HN Nweke, Edidiong Idio, Darlington Okey, Cletus Ozibo

Subjects: “…Antipsychotics…”
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The Role of Neuroglia in the Development and Progression of Schizophrenia by Neha S. Rawani, Allen W. Chan, Kathryn G. Todd, Glen B. Baker, Serdar M. Dursun

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Role of Cannabis in the Management of Chronic Non-Cancer Pain: A Narrative Review by Lou’i Al-Husinat, Shrouq Obeidat, Saif Azzam, Yara Al-Gwairy, Fatima Obeidat, Sarah Al Sharie, Deema Haddad, Fadi Haddad, Martina Rekatsina, Matteo Luigi Giuseppe Leoni, Giustino Varrassi

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Delirium is one of the many faces of COVID-19. Literature review by A. Bagdonaitė, D. Tumas, E. Griškevičiūtė, A. Svirskytė

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Expression study of Wnt/β-catenin signaling pathway associated lncRNAs in schizophrenia by Fatemeh Manafzadeh, Behzad Baradaran, Seyed Gholamreza Noor Azar, Kamran Javidi Aghdam, Reza Dabbaghipour, Asghar Shayannia, Soudeh Ghafouri-Fard

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Anticholinergic burden and behavioral and psychological symptoms in older patients with cognitive impairment by Sabrina Pistorio, Gianluca Scotto di Tella, Vittoria Canzanella, Raffaella Merenda, Gianluigi Cuomo, Paola Iacotucci, Vincenzo Carnovale, Leonardo Bencivenga, Maria Vargas, Annalaura Manes, Mauro Cataldi, Giuseppe Rengo, Giuseppe Rengo, Michela Zanetti, Grazia Daniela Femminella, Grazia Daniela Femminella

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Editorial: Drug repurposing for cancer treatment: current and future directions by Marios Lampros, Nikolaos Vlachos, Georgios D. Lianos, Christina Bali, George A. Alexiou

Subjects: “…antipsychotics - treatment…”
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Indian Psychiatric Society multicentre study: Diagnostic patterns, comorbidity and prescription practices for patients with Dementia by CT Sudhir Kumar, Mathew Varghese, Venugopal Duddu, Sridhar Vaitheswaran, Shrikant Srivastava, KS Shaji, Sanju George, Narendra Kumar Singh, Nishant Goyal, Ajay Bakhla, S Shaji, Vikas Menon, Tajamul Hussain, Sandeep Grover, Aseem Mehra, Lokesh Kumar Singh, A Purushotham, Avinash Desousa, Nilesh Shah, Sagar Karia, I Anand, Shafana Afroon, Ritambhara Mehta, Gargi Kukreja, Dimple Dadarwala, KL Vidya, PT Sivakumar, Preeti Sinha, Shivashankar Reddy, Thomas Isaac, Mina Chandra

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MORE ATTENTION TO QUALITY OF PHARMACOTHERAPY IN PSYCHIATRY by ERKKI ISOMETSÄ

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Impact of cariprazine on body weight and blood pressure among adults with bipolar I disorder, schizophrenia, or major depressive disorder in a real-world setting by Christoph U. Correll, Andrew J. Cutler, François Laliberté, Guillaume Germain, Sean D. MacKnight, Julien Boudreau, Sally W. Wade, Nadia Nabulsi, Huy-Binh Nguyen, Mousam Parikh

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Association between treatment resistance and cognitive function in schizophrenia by Jiaqian Sun, Jie Yin Yee, Yuen Mei See, Charmaine Tang, Shushan Zheng, Boon Tat Ng, Jimmy Lee

“…The planned statistical analyses included adjustments for covariates such as age, sex, PANSS scores and antipsychotic dose, which might affect cognitive function. …”
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Neuroleptic Malignant Syndrome: Diagnostic and Therapeutic Dilemmas by Abebaw Fekadu, Jonathan I. Bisson

“…Neuroleptic malignant syndrome (NMS) is a life threatening medical state complicating the use of antipsychotic medications and other drugs that affect the dopaminergic system on administration or withdrawal. …”
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Maintenance Electroconvulsive Therapy in a Patient with Treatment-Resistant Paranoid Schizophrenia and Comorbid Epilepsy by Beppe Micallef-Trigona, Joseph Spiteri

“…The treatment of choice for acute schizophrenia is antipsychotic drug treatment and electroconvulsive therapy (ECT) and should only be considered as an option for treatment-resistant schizophrenia, where treatment with clozapine has already proven ineffective or intolerable. …”
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The short-, medium-, and long-term prevalence of physical health comorbidities in first-episode psychosis: a systematic review and meta-analysis protocol [version 2; peer review: 3... by Michael Norton, Brian O'Donoghue, Mary Clarke, Karen O'Connor, Jennifer Murphy, Anna Zierotin

“…Longitudinal studies and antipsychotic intervention studies monitoring health outcomes in antipsychotic naïve FEP individuals will be eligible for inclusion. …”
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New role of platelets in schizophrenia: predicting drug response by Tao Li, Wei Wei, Qiang Wang, Yamin Zhang, Wei Deng, Rui Xue, Wanjun Guo, Xiaojing Li, Hua Yu, Yanghao Zheng, Peiyan Ni, Sugai Liang, Xueyu Qi, Xueli Yu, Liansheng Zhao

“…However, the impact of antipsychotic medications on PLTc and its association with symptom improvement remain unclear.Aims We aimed to investigate changes in PLTc levels following antipsychotic treatment and assess whether PLTc can predict antipsychotic responses and metabolic changes after accounting for other related variables.Methods A total of 2985 patients with schizophrenia were randomised into seven groups. …”
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Synthesis, Computational Studies and Preliminary Pharmacological Evaluation of New Arylpiperazines by Sushil Kumar, A. K. Wahi, Ranjit Singh

“…Among them, compound 3d has emerged as an important lead compound showing potential atypical antipsychotic like profile.…”
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