Long-Acting Injectable Antipsychotic Use in Patients with Schizophrenia and Criminal Justice System Encounters by Madhav P. Bhatta, Saroj Bista, Antoine C. El Khoury, Eric G. Hutzell, Neeta Tandon, Douglas Smith

“…**Objective:** To assess the association between long-acting injectable (LAI) antipsychotic use and criminal justice system encounters in patients with schizophrenia or schizoaffective disorder. …”
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Follow-up Care among Medicaid Patients with Schizophrenia treated with Antipsychotics in the Inpatient Setting by Amanda M. Farr, David M. Smith, Jacqueline A. Pesa, Zhun Cao

“…To date, there is little information regarding the association between inpatient antipsychotic treatment and outpatient care. **Objectives:** The objectives of this study were to describe trends in and identify factors associated with post-discharge follow-up outpatient care among Medicaid enrollees with schizophrenia treated with antipsychotics. …”
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Treatment of a schizophrenia patient on long-term super-dose antipsychotics: a case report by Xiaobo Xie, Jinzhang Chen, Hongli Song, Zebin Fan

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Overview of Novel Antipsychotic Drugs: State of the Art, New Mechanisms, and Clinical Aspects of Promising Compounds by Letizia Biso, Marco Carli, Marco Scarselli, Biancamaria Longoni

Subjects: “…novel antipsychotics…”
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Augmentation of Antipsychotic Medications with Low-Dose Clozapine in Treatment-Resistant Schizophrenia—Case Reports and Discussion by Zoe Harrison, Owen Haeney, William Brereton

“…This paper presents a review of the relevant literature and three cases of a novel approach, utilising clozapine in doses usually considered subtherapeutic, in combination with the primary antipsychotic treatment. In all three patients, it improved clinical efficacy as well as tolerability, resulting in improvement that allowed discharge from the forensic hospital.…”
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Treatment of tardive dyskinesia caused by long-term antipsychotic use: case reports and literature review by I. Pabarčiūtė, M. Karnickas

“…These agents include most of antipsychotics, which are widely used to treat mental illness. …”
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THEORETICAL AND INSILCO PHARMACOKINETIC INVESTIGATIONS ON SOME PHENYL PIPERIDINE DERIVATIVES AS NOVEL ANTIDEPRESSANT AGENTS by Olasupo Sabitu Babatunde Babatunde, Adamu Uzairu, Gideon Adamu Shallangwa, Sani Uba

Subjects: “…Serotonin; antipsychotic; QSAR; Descriptors; Model…”
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Association between a publicly funded universal drug program and antipsychotic and antidepressant medication dispensing to children by Sophie A. Kitchen, Tara Gomes, Mina Tadrous, Kathleen Pajer, William Gardner, Yona Lunsky, Melanie Penner, David Juurlink, Muhammad Mamdani, Tony Antoniou

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Can incentives improve antipsychotic adherence in major mental illness? A mixed-methods systematic review by Nathan Hodson, Ivo Vlaev, Madiha Majid, Swaran Preet Singh

“…Searches on 13 January 2021 (no start date) found papers on incentives for antipsychotics. Randomised controlled trials (RCTs), cohort studies, qualitative research and ethical analyses were included. …”
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Oral versus long-acting injectable antipsychotic in first episode schizophrenia: A 12 weeks interventional study by Ramandeep Kaur, Ajeet Sidana, Nidhi Malhotra, Shikha Tyagi

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Feasibility of a pharmacist-led physical health monitoring for patients on antipsychotic medications: protocol for a longitudinal study by Fiona Kelly, Tien Ngoc Thi Bui, Elizabeth Hotham, Vijayaprakash Suppiah

“…It has been recognised that commonly prescribed pharmacological agents for mental illness can further amplify the risk of developing metabolic syndrome; therefore, monitoring guidelines are in place for consumers prescribed antipsychotics. However, there is a disconnect between recommended guidelines and current practice. …”
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New Insights in the Management of Antipsychotics in the Treatment of Schizophrenia in a Patient with Prolactinoma: A Case Report and Review of the Literature by Elvis Henrique Santos Andrade, Pedro Mario Pan, Paula F. Ramalho da Silva, Ary Gadelha

“…Schizophrenia treatment is based on antipsychotics, which acts mainly at serotonergic and dopaminergic systems. …”
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Direct and Indirect Drug Design Approaches for the Development of Novel Tricyclic Antipsychotics: Potential 5-HT2A Antagonist by Mahantesh Namdev Jadhav, Ganesh Rajendra Kokil, Shilpa Sudhakar Harak, Sanjay Baburao Wagh

“…Given the therapeutic and toxic limitations of clinically available drugs, it is clear that there is still a need for the development of new generation antipsychotic agents with an improved clinical profile. …”
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Switching antipsychotics: Results of 16-month non-interventional, prospective, observational clinical research of inpatients with schizophrenia spectrum disorders by Bole Cvetka Bačar, Pišlar Mitja, Šen Metka, Tavčar Rok, Mrhar Aleš

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Auditing Clinical Outcomes after Introducing Off-Licence Prescribing of Atypical Antipsychotic Melperone for Patients with Treatment Refractory Schizophrenia by Frank Röhricht, Seema Gadhia, Rinku Alam, Melissa Willis

“…To evaluate the practical utility of off-licence prescribing and clinical outcomes of treatment with atypical antipsychotic Melperone. Method: Prospective data collection on patient’s clinical characteristics and outcomes. …”
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Shared decision-making interventions in the choice of antipsychotic prescription in people living with psychosis (SHAPE): Protocol for a realist review. by Ita Fitzgerald, Laura J Sahm, Jo Howe, Ian Maidment, Emma Wallace, Erin K Crowley

“…<h4>Methods</h4>This review will use realist review methodology to provide a causal understanding of how and why interventions work when implementing SDM during antipsychotic treatment choices. The cohort of interest will be those experiencing psychosis where ongoing treatment with an antipsychotic is clinically indicated. …”
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Machine learning-based prediction of antipsychotic efficacy from brain gray matter structure in drug-naive first-episode schizophrenia by Xiaodong Guo, Enpeng Zhou, Xianghe Wang, Bingjie Huang, Tianqi Gao, Chengcheng Pu, Xin Yu

“…Abstract Predicting patient response to antipsychotic medication is a major challenge in schizophrenia treatment. …”
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Silent Neuroleptic Malignant Syndrome: A Case Report of Atypical Antipsychotic Induced Elevation of Creatinine Kinase and Altered Mental Status by Amber N. Edinoff, Hamza Mohammad-Amin, Amira S. Odisho

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Sex differences in the peripheral levels of cytokines during 12-month antipsychotic treatment in a drug-naïve schizophrenia spectrum cohort by I. Ratke, A. Torsvik, C.A. Bartz-Johannessen, F. Fathian, I. Joa, S.M. Klæbo Reitan, E.M. Løberg, M. Rettenbacher, S. Skrede, V.M. Steen, E. Johnsen, R.A. Kroken

“…However, research addressing sex differences regarding the antipsychotic effect on the immune system is lacking. …”
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Effects of Antipsychotic Drugs on the Epigenetic Modification of Brain-Derived Neurotrophic Factor Gene Expression in the Hippocampi of Chronic Restraint Stress Rats by Mi Kyoung Seo, Young Hoon Kim, Roger S. McIntyre, Rodrigo B. Mansur, Yena Lee, Nicole E. Carmona, Ah Jeong Choi, Gyung-Mee Kim, Jung Goo Lee, Sung Woo Park

“…Recent studies have shown that antipsychotic drugs have epigenetic effects. However, the effects of antipsychotic drugs on histone modification remain unclear. …”
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