Development and characterization of a chicory extract fermented by Akkermansia muciniphila: An in vitro study on its potential to modulate obesity-related inflammation by A. Chervet, R. Nehme, C. Defois-Fraysse, C. Decombat, C. Blavignac, C. Auxenfans, B. Evrard, S. Michel, E. Filaire, J.-Y. Berthon, A. Dreux-Zigha, L. Delort, F. Caldefie-Chézet

“…Chicory extract fermented by Akkermansia muciniphila (C-Akm) was selected as the most antioxidant of 20 fermented extracts. The identification of metabolites derived from C-Akm extract has enabled us to detect mostly amino acids, acids, and some polyphenols (daidzein and genistein). …”
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Perbedaan Kadar Superokside Dismutase pada Remaja dengan Dismenore Primer dan Tanpa Dismenore Primer by Yanti ., Ermawati ., Eliza Anas

“…</em><em></em></p><p class="normal"><strong><em>Keywords:</em></strong><em> adolescent, dysmenorrea, antioxidant, superoxide dismutase</em></p>…”
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Exploring the Mechanisms of Iron Overload-Induced Liver Injury in Rats Based on Transcriptomics and Proteomics by Yujia Shu, Xuanfu Wu, Dongxu Zhang, Shuxia Jiang, Wenqiang Ma

“…In conclusion, the findings of this study suggest that by suppressing the expression of Lnc286.2, we can enhance the expression of HO-1, which in turn alleviates lipid peroxidation in cells and increases their antioxidant capacity, thereby exerting a protective effect against liver cell injury induced by iron overload.…”
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Effect of Whole Wheat Noodles on Biochemical Indexes and Histopathology of Type 2 Diabetic Rats by Li WU, Yuan ZHANG, Chunhong TANG, Huan YOU, Haijun CHANG, Shuai ZHANG

“…Additionally, it increased the content of high-density lipoprotein (HDL-C), with a significant increase of 21.83% in the high-dose group (P<0.05). The total antioxidant capacity (T-AOC), superoxide dismutase (SOD) activity, glutathione peroxidase (GSH-Px) activity, and catalase (CAT) activity significantly increased (P<0.05), while the content of malondialdehyde (MDA) extremely significant decreased (P<0.01). …”
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Effects of isoquinoline alkaloids as an alternative to antibiotic on oxidative stress, inflammatory status, and cecal microbiome of broilers under high stocking density by Kittisak Insawake, Thaweesak Songserm, Ornprapun Songserm, Atthawoot Plaiboon, Nitipong Homwong, Kazeem D. Adeyemi, Konkawat Rassmidatta, Yuwares Ruangpanit

“…BCT50 modulated microbial functions, particularly those related to cell wall synthesis, while isoquinoline alkaloids upregulated pathways involved in energy production, secondary metabolite biosynthesis, and antioxidant production. Both Bacitracin and isoquinoline alkaloids were effective in mitigating the negative effects of HSD on immunity, gut health and microbiota in broilers. …”
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Metabolomics and transcriptomics analyses revealed overexpression of TaMGD enhances wheat plant heat stress resistance through multiple responses by Dongyun Ma, Haizhou Hu, Jianchao Feng, Beiming Xu, Chenyang Du, Yang Yang, Yingxin Xie, Chenyang Wang

“…Under high-temperature stress, the overexpressed wheat lines exhibited higher grain weight, increased antioxidant enzyme activity, and lower H2O2 and malondialdehyde contents in leaves. …”
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Fatty acid synthase inhibition improves hypertension-induced erectile dysfunction by suppressing oxidative stress and NLRP3 inflammasome-dependent pyroptosis through activating the... by Jiaochen Luan, Mengchi Yu, Qi Gu, Xuan Zhou, Yunqiang Shao, Tong Chen, Jiayi Zhang, Zheng Zhu, Ninghong Song, Jie Yang

“…In vitro, siFasn and C75 enhanced antioxidant markers Nrf2 and HO-1, reduced ROS accumulation, and suppressed NLRP3 and GSDMD levels. …”
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Inducing salt stress tolerance in bitter gourd (Momordica chanrantia) through seed treatment with chitosan by Ahsan Ali, Fiaz Hussain Ferdosi, Mubeen Sarwar, Sumreen Anjum, Zain Mushtaq, Mehwish Liaquat, Muhammad Taqqi Abbas, Moazzam Anees, Muhammad Rizwan Tariq, M. Irfan Ashraf, Abdulrahman Alasmari, Md Sabir Ahmed Mondol, Gholamreza Abdi

“…MethodsThe present study was designed to evaluate the various morphological attributes (mean germination time, germination index, final emergence percentage, measurements of root length, measurement of shoot length, measurement of plant dry biomass, and measurement of plant fresh biomass), physiological attributes (leaf chlorophyll content and electrolyte leakage), biochemical attributes (proline contents, antioxidant enzymes, superoxide dismutase, catalase Q9 , and peroxidase), leaf water relations (leaf osmotic potential, leaf water potential, leaf turgor potential, and leaf relative water content), and ion concentrations (Na+, K+, Ca +, and Cl-) that can be used for the evaluation of salt stress tolerance potential in bitter gourd. …”
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Preclinical Evidences for an Antimanic Effect of Carvedilol by Greicy Coelho de Souza, Julia Ariana de S. Gomes, Ana Isabelle de Góis Queiroz, Maíra Morais de Araújo, Lígia Menezes Cavalcante, Michel de Jesus Souza Machado, Aline Santos Monte, David Freitas de Lucena, João Quevedo, André Ferrer Carvalho, Danielle Macêdo

“…Carvedilol (CVD), a nonselective beta-blocker widely used for the treatment of hypertension, presents antioxidant and mitochondrial stabilizing properties. …”
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TaSnRK3.23B, a CBL-interacting protein kinase of wheat, confers drought stress tolerance by promoting ROS scavenging in Arabidopsis by Feiyan Dong, Yide Liu, Huadong Zhang, Yaqian Li, Jinghan Song, Sheng Chen, Shuailei Wang, Zhanwang Zhu, Yan Li, Yike Liu

“…TaSnRK3.23B overexpression in Arabidopsis promoted reactive oxygen species (ROS) scavenging via the accumulation of antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), and peroxidase (POD) and then conferred significant tolerance to drought. …”
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Beetroot (Beta vulgaris L.) Extract Ameliorates Gentamicin-Induced Nephrotoxicity Associated Oxidative Stress, Inflammation, and Apoptosis in Rodent Model by Ali A. El Gamal, Mansour S. AlSaid, Mohammad Raish, Mohammed Al-Sohaibani, Shaza M. Al-Massarani, Ajaz Ahmad, Mohamed Hefnawy, Mohammed Al-Yahya, Omer A. Basoudan, Syed Rafatullah

“…BVEE (250 and 500 mg/kg) treatment along with gentamicin restored/increased the renal endogenous antioxidant status. Gentamicin-induced increased renal inflammatory cytokines (TNF-α and IL-6), nuclear protein expression of NF-κB (p65), NF-κB-DNA binding activity, myeloperoxidase (MPO) activity, and nitric oxide level were significantly down regulated upon BVEE treatment. …”
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Biomimetic polydopamine loaded with janus kinase inhibitor for synergistic vitiligo therapy via hydrogel microneedles by Chunying Li, Wenwen Wang, Junyi Shao, Sen Zhou, Xiaolin Ji, Youxia Xi, Qiuyang Xu, Yuhan Huang, Jingle Wang, Yilin Wan, Zhiming Li

“…Specifically, we have incorporated the janus kinase inhibitor (JAKi) tofacitinib into antioxidant polydopamine (PDA) nanoparticles, resulting in the formation of uniform PDA-JAKi nanodrug. …”
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Alpinetin Attenuates Persistent Inflammation, Immune Suppression, and Catabolism Syndrome in a Septic Mouse Model by Yukun Liu, Kang Wang, Qaunrui Feng, Yongsheng Zhang, Chuntao Wang, Qinxin Liu, Xinghua Liu, Xiang Wang, Wei Gao, Xiangjun Bai, Zhanfei Li, Yuchang Wang

“…Alpinetin is a flavonoid isolated from Alpinia katsumadai Hayata that has been demonstrated to have anti-inflammatory, antibacterial, and antioxidant activities. The aim of this study was to investigate whether the administration of alpinetin could attenuate PICS in a septic mouse model. …”
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Mimosapudica L. aqueous extract protects mice against pilocarpine–picrotoxin kindling-induced temporal lobe epilepsy, oxidative stress, and alteration in GABAergic/cholinergic path... by Hart Mann Alain Youbi Mambou, Simon Pale, Orelien Sylvain Mtopi Bopda, Vanessa Tita Jugha, Nji Seraphin Ombel Musa, Tambong Ako Ojongnkpot, Bertrand Yuwong Wanyu, Raymond Bess Bila, Rashed N. Herqash, Abdelaaty A. Shahat, Germain Sotoing Taiwe

“…Pilocarpine–picrotoxin-induced alteration of oxidant–antioxidant balance, GABA-transaminase stability, acetylcholinesterase/butyrylcholinesterase activity, and neurogenesis were attenuated by the extract (80–160 mg/kg). …”
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Therapeutic and Safety Evaluation of Combined Aqueous Extracts of Azadirachta indica and Khaya senegalensis in Chickens Experimentally Infected with Eimeria Oocysts by J. G. Gotep, J. T. Tanko, G. E. Forcados, I. A. Muraina, N. Ozele, B. B. Dogonyaro, O. O. Oladipo, M. S. Makoshi, O. B. Akanbi, H. Kinjir, A. L. Samuel, T. E. Onyiche, G. O. Ochigbo, O. B. Aladelokun, H. A. Ozoani, V. Z. Viyoff, C. C. Dapuliga, A. A. Atiku, P. A. Okewole, D. Shamaki, M. S. Ahmed, C. I. Nduaka

“…There were decreased intestinal lesions and enhanced antioxidant activity across the treatment groups compared to the negative control. …”
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Based on bioinformatics, SESN2 negatively regulates ferroptosis induced by ischemia reperfusion via the System Xc−/GPX4 pathway by Jiejie Hu, Lijun Qin, Guoqiang Zhu, Jingjing Ren, Hongxia Wang, Jing Jin, Haixue Zheng, Dan Li, Zhaoming Ge

“…SESN2 is a hub gene and key antioxidant regulator. SESN2 silencing reduced the expression of System Xc− and GPX4, whereas overexpression of SESN2 promoted the expression of System Xc− and GPX4.DiscussionThese results suggest that SESN2 is a negative regulator of ferroptosis. …”
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GLP‐1 Receptor Agonists Alleviate Diabetic Kidney Injury via β‐Klotho‐Mediated Ferroptosis Inhibition by Shasha Tian, Saijun Zhou, Weixi Wu, Yao lin, Tongdan Wang, Haizhen Sun, A‐Shan‐Jiang A‐Ni‐Wan, Yaru Li, Chongyang Wang, Xiaogang Li, Pei Yu, Yanjun Zhao

“…Subsequently, the adenosine monophosphate‐activated protein kinase (AMPK) signaling pathway is activated, reprograming the key metabolic processes of ferroptosis such as iron metabolism, fatty acid synthesis, and the antioxidant response against lipid peroxidation. Suppression of ferroptosis by Smg further attenuates renal inflammation and fibrosis. …”
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Microglial Nrf2-mediated lipid and iron metabolism reprogramming promotes remyelination during white matter ischemia by Hang Zhang, Sheng Yang, Yi-Lin Lu, Luo-Qi Zhou, Ming-Hao Dong, Yun-Hui Chu, Xiao-Wei Pang, Lian Chen, Lu-Lu Xu, Lu-Yang Zhang, Li-Fang Zhu, Ting Xu, Wei Wang, Ke Shang, Dai-Shi Tian, Chuan Qin

“…Conclusion: Weakened Nrf2-mediated antioxidant responses in microglia induced metabolic disturbances and ferroptosis during chronic cerebral hypoperfusion. …”
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Phytochemical and Metabolomic Investigation of a Popular Traditional Plant from La Réunion: <i>Psiloxylon mauritianum</i> by Théo Ozga, Gaëtan Herbette, Patrick Carriere Richez, Patricia Clerc, Juliano Haddad, Chaker El Kalamouni, Jérôme Bignon, Rémy Marcellin-Gros, Emerson Ferreira Queiroz, Jean-Luc Wolfender, Jacqueline Smadja, Anne Gauvin-Bialecki

“…Some compounds from these molecular classes are reported to target fever-linked symptoms (antioxidant, antiviral, anti-inflammatory, and antibacterial activities) and may explain the plant’s success as a local traditional remedy. …”
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Shatavari supplementation during eight weeks of resistance training increases training load, enhances skeletal muscle contractility and alters the skeletal muscle proteome in older... by Elsa Greed, Elsa Greed, Jack Pritchard, Lauren Struszczak, Esra Bozbaş, Georgia Ek, Jordan Acheson, Jordan Acheson, Ben Winney, Aaliyah Qadir, Karl Ka-Lam Wong, Joanna Bowtell, Mary O’Leary

“…Shatavari contains compounds with both estradiol-like and antioxidant properties, which could enhance muscle function. …”
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