The effects of Lepidium meyenii on MSG-induced subfertility in male Wistar rats: Targeting oxidative stress, pro-inflammatory cytokines, steroidogenic enzymes, and reproductive hor... by Temidayo S. Omolaoye, Surendra Singh Rawat, Naglaa Gamil Shehab, Eslam El Nebrisi, Stefan S. Du Plessis

“…Results: MSG administration significantly reduced total and progressive sperm motility (p < 0.05), decreased total antioxidant capacity (TAC) (p < 0.001), increased mRNA expression of TNF-α, IL-6, IL-1β in the testis and prostate (p < 0.05), protein expression of GP130 in the testis, reduced serum testosterone, and altered expression of steroidogenic markers. …”
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Exploring the potential of underrated yet versatile crop Lunaria annua L.: New insights into honesty plant by Jovana Petrović, Daiana Almeida, Ângela Fernandes, Dejan Stojković, Dragana Robajac, Tayse F.F. da Silveira, Lillian Barros

“…Methanolic extract showed better antioxidant potential than dichloromethane extract (EC50 = 0.32 vs. 1.25 mg/mL, in TBARS test). …”
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Effects of deoxynivalenol contaminated corn distiller's dried grains with solubles on growth performance, body composition, immunological response, and gastrointestinal health in y... by Deependra Paneru, Milan K. Sharma, Hanyi Shi, Doyun Goo, Venkata S.R. Choppa, Ishwari Gyawali, Revathi Shanmugasundaram, Woo K. Kim

“…Gut health was compromised as gut permeability increased linearly with increasing DDGS inclusion (linear, P = 0.043), aligning with significant alterations in the expression of the tight junction protein occludin (OCLN; P = 0.007). Antioxidant responses in the liver showed increased superoxide dismutase (SOD) activity in early exposure (day 13, P = 0.038), followed by decreased SOD activity (P = 0.001) and reduced glutathione (GSH) levels (P < 0.001) by day 28. …”
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Impact of mango peel pectin and Bacillus iranensis on growth, immunity, and gene expression in Nile tilapia (Oreochromis niloticus) by Anisa Rilla Lubis, Nguyen Vu Linh, Khambou Tayyamath, Supreya Wannavijit, Punika Ninyamasiri, Chanagun Chitmanat, Wanaporn Tapingkae, Einar Ringø, Hien Van Doan, Maria Ángeles Esteban

“…These findings suggest that the dietary inclusion of mango peel pectin and Bacillus iranensis as a synbiotic supplement can significantly enhance growth performance, immunity, and the expression of certain immune and antioxidant related genes in Nile tilapia. This highlights their potential as effective feed additives for improving fish health and supporting sustainable aquaculture practices.…”
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Incorporation of reduced glutathione to the extender improves frozen-thawed sperm function and fertility potential in mandarin fish (Siniperca chuatsi) by Sen Yang, Wenjie Xu, Yanglin Hua, Qingxin Ruan, Zining Meng

“…Supplementation of antioxidant in the freezing medium is suggested to be an effective strategy against cryodamage. …”
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A lignin-based controlled/sustained release hydrogel by integrating mechanical strengthening and bioactivities of lignin by Bowei Wang, Dingkun Qiu, Yihui Gu, Zhu Shan, Ruonan Shi, Jing Luo, Shuang Qi, Yilin Wang, Bo Jiang, Yongcan Jin

“…The favorable antioxidant and antimicrobial activities of lignin have been shown to promote wound healing. …”
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Potential Effect of Exosomes Derived from Cancer Stem Cells and MSCs on Progression of DEN-Induced HCC in Rats by Faisal A. Alzahrani, Mohammed A. El-Magd, Ahmed Abdelfattah-Hassan, Ayman A. Saleh, Islam M. Saadeldin, Eman S. El-Shetry, Abdelnaser A. Badawy, Saleh Alkarim

“…However, both CSCs- and MSCs-exosomes failed to change the elevated oxidative stress or the inhibited antioxidant activities induced by HCC. Collectively, our results revealed a tumor stimulatory effect (induction of tumor growth, progression, and metastasis) for exosomes derived from CSCs and an inhibitory effect for exosomes derived from MSCs. …”
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Molecular mechanisms of aflatoxin neurotoxicity and potential neuroprotective agents by Chongshan Dai, Erjie Tian, Hui Li, Subhajit Das Gupta, Zhihui Hao, Zhanhui Wang, Tony Velkov, Jianzhong Shen

“…Mechanistically, AFB1 exposure has been associated with lipid peroxidation, ablation of non-enzymatic and enzymatic antioxidant defense systems and decreased neurotransmitter levels. …”
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Olfactory mucosa-mesenchymal stem cells with overexpressed Nrf2 modulate angiogenesis and exert anti-inflammation effect in an in vitro traumatic brain injury model by Zigui Chen, Chunyuan Zhang, Yuhua Fang, He Zhang, Jiawei Luo, Changfeng Miao, Jiale Li, Jun Peng, Yingqi Qiu, Ying Xia, Qisheng Luo

“…Transcription factor nuclear factor erythroid-derived 2-like 2 (Nrf2) has antioxidant, anti-inflammatory and neuroprotective effects and is closely related to TBI. …”
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Screening of Efficient Antifreeze Agents to Prevent Low-Temperature Stress in Vines by Yali Zhang, Mengyao Han, Langjie Wu, Haoyu Wang, Yanying Liang, Xianhang Wang, Zhumei Xi

“…Compared to the control (water), all four antifreeze agents significantly reduced the relative conductivity and malondialdehyde content in the tender shoots of both grape varieties, increased the Fv/Fm ratio, enhanced osmotic adjustment substance levels, and improved antioxidant enzyme activity. Moreover, relative conductivity and malondialdehyde content were significantly lower, and the Fv/Fm ratio was higher when the antifreeze agents were applied 24 h before frost compared to 48 h. …”
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Baccaurea ramiflora fruit peel powder supplementation prevented inflammatory cell infiltration, oxidative stress, and fibrosis in carbon tetrachloride (CCl4) administered ovariecto... by Tahsin Zahan, Mirza Alimullah, Ishrat Jahan, Md. Borhan Uddin, Khondker Ayesha Akter, Md. Junaeid Rahman, Shahnaz Siddiqua, Kamrun Nahar Ela, Sakil Amin, Khondoker Shahin Ahmed, Hemayet Hossain, Ferdous Khan, Md Ashraful Alam, Nusrat Subhan

“…This protection is achieved by mitigating lipid peroxidation, reducing oxidative stress and inflammation, alleviating fibrosis, and enhancing the cellular antioxidant system.…”
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Comparative Evaluation of Intra-articular Ozone and Steroid Treatments in Patients with Coxarthrosis under Ultrasound Guidance: A Retrospective Study by Yilmaz Karaduman, Arzu Muz, Azize Serçe, Servi Yildirim, Ismail Eren Durmus, Suna Akin Takmaz

“…Additionally, it affects inhibitory cytokines, antioxidant enzymes, and neo-angiogenesis. Aim: To evaluate and compare the effectiveness of USG intra-articular ozone therapy versus corticosteroid injections in managing hip OA (coxarthrosis) in patients who have not responded to conventional treatments. …”
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Preventive but Not Curative Efficacy of Celecoxib on Bladder Carcinogenesis in a Rat Model by José Sereno, Belmiro Parada, Flávio Reis, Fernanda X. Cunha, Edite Teixeira-Lemos, Patrícia Garrido, Rui Pinto, Petronila Rocha-Pereira, Paula Neto, José Ruivo, Paulo Rodrigues-Santos, Sara Nunes, Alfredo Mota, Arnaldo Figueiredo, Frederico Teixeira

“…An anti-inflammatory and antioxidant profile was encountered only in the group under preventive treatment. …”
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Hydrogen-oxygen mixture inhalation as an adjunctive treatment to home-based exercise in older patients with knee osteoarthritis: an open-label, blinded-endpoint, randomized control... by Chenhui Wang, Mengwei Yan, Yuru Li, Lei Han, Hongqian Wang, Shufeng Jia, Xingchen Liu, Yang Liu, Fan Wu, Baoguo Wang

“…Molecular hydrogen has been proven to have antioxidant and anti-inflammatory properties, but few studies have investigated its effects on osteoarthritis. …”
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CC16 alleviates PM2.5-induced lung epithelial cell injury and airway inflammation in asthmatic mice by inhibiting ferroptosis by Aili Wang, Jianling Liu, Zhangwen Li, Ze Qian, Shuo Yang, Shaohua Luo, Jinle Lin, Jian Wu

“…Club Cell 16 kDa protein (CC16), recognized for its anti-inflammatory and antioxidant properties, may serve a protective function in asthma exacerbated by PM2.5; however, the underlying mechanisms, particularly those related to ferroptosis, remain poorly understood. …”
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Ginsenoside Rg1: A bioactive therapeutic agent for diverse liver diseases by Mingyu Wu, Ke Li, Jiabin Wu, Xianyi Ding, Xiaotong Ma, Wenhong Wang, Weihua Xiao

“…., which mainly rely on the inhibition of apoptosis, strengthening endogenous anti-inflammatory and antioxidant mechanisms, activation of immune responses and regulation of efflux transport signals, to improve pathological changes in the liver caused by lipid deposition, inflammation, oxidative stress, accumulation of hepatotoxic product, etc. …”
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Kinetics of Supercritical CO₂ Extraction from Burrito (<i>Aloysia polystachya</i>) Leaves and Sucupira-Preta (<i>Bowdichia virgilioides</i>) Seeds by Gabrielle Vaz Vieira, Michel Rubens dos Reis Souza, Carlos Toshiyuki Hiranobe, José Eduardo Goncalves, Cristiane Mengue Feniman Moritz, Otávio Akira Sakai, Leila Maria Sotocorno e Silva, Michael Jones da Silva, Erivaldo Antônio da Silva, Renivaldo José dos Santos, Edson Antônio da Silva, Lucio Cardozo-Filho, Leandro Ferreira-Pinto

“…Despite their relatively low yields, the extracts contained a diverse range of chemical compounds, including fatty acids (oleic, linoleic, and palmitic acids), squalene, β-carotene, vitamin E, and other bioactive molecules with antioxidant, anti-inflammatory, and immunomodulatory properties. …”
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Oxidative balance score was negatively associated with the risk of metabolic syndrome, metabolic syndrome severity, and all-cause mortality of patients with metabolic syndrome by Zhixiao Xu, Xiong Lei, Weiwei Chu, Luoqi Weng, Chengshui Chen, Chengshui Chen, Chengshui Chen, Ran Ye

“…Health outcomes for MetS patients were positively related to antioxidant diets and lifestyles.…”
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The potential impact of glycine supplementation on the process of aging by Michalina Wójcikiewicz, Julia Kulbacka, Witold Czyż, Julia Kacperczyk, Karol Dziedzic, Marta Chuncia-Ileczko, Maciej Wojszczyk, Damian Zys, Piotr Pasek, Julia Ryniecka, Wiktor Czaja, Michał Krzciuk

“…Beyond its structural role in collagen and other proteins, glycine is a critical precursor for glutathione- an essential intracellular antioxidant- plays a role in neurotransmission, and is involved in the synthesis of heme, creatine, and bile acids. …”
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JNK and NADPH Oxidase Involved in Fluoride-Induced Oxidative Stress in BV-2 Microglia Cells by Ling Yan, Shengnan Liu, Chen Wang, Fei Wang, Yingli Song, Nan Yan, Shuhua Xi, Ziyou Liu, Guifan Sun

“…NOX inhibitor apocynin and iNOS inhibitor SMT dramatically decreased NaF-induced ROS and NO generations, respectively. Antioxidant melatonin (MEL) resulted in a reduction in JNK phosphorylation in fluoride-stimulated BV-2 microglia. …”
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