-
3981
Valorization of local regional apple (Malus domestica Borkh.) cultivars versus commercial samples from Spain: Phenolic compounds by HPLC-MS/MS, cytotoxicity and biological potentia...
Published 2025-01-01“…For a deeper understanding of their anti-inflammatory and antioxidant potential, the 5-lipoxigenase inhibition and NO− scavenging were evaluated. …”
Get full text
Article -
3982
Influence of diglyme and cumene additives upon emission and combustion behaviour of diverse biodiesel fuelled diesel engine
Published 2025-03-01“…/vol.) functioned as an antioxidant. The results demonstrated that the blends MME15+CU5 and MME15+DG5 exhibited superior thermo-chemical properties and engine performance. …”
Get full text
Article -
3983
Ex vivo biotransformation of lady’s mantle extracts via the human gut microbiota: the formation of phenolic metabolites and their impact on human normal and colon cancer cell lines...
Published 2025-01-01“…(Rosaceae) stands out as a promising herbal drug candidate due to its phytochemicals displaying anti-inflammatory and antioxidant properties.MethodsIn our study, we investigated the interaction between the human gut microbiota and lady’s mantle herb extract (AV) following the biotransformation of the extract’s constituents and their impact on colorectal cancer cells (HT-29) and normal CCD 841 CoN epithelial cells. …”
Get full text
Article -
3984
Pathogenesis-directed therapy of methylphenidate-induced oxidative heart damage in rats
Published 2025-01-01“…Oxidant levels were lower and antioxidant levels were higher in ATMP, MSMP, and MLMP groups compared to MP group (p < 0.001). …”
Get full text
Article -
3985
Exploring the noncovalent interaction between β-lactoglobulin and flavonoids under nonthermal process: Characterization, physicochemical properties, and potential for lycopene deli...
Published 2025-01-01“…The thermal stability, surface hydrophilicity, and antioxidant properties of β-LG-API, β-LG-LUT, and β-LG-MY complexes were superior by multi-spectroscopy methods and molecular simulation analysis (P < 0.05). …”
Get full text
Article -
3986
Comparative effects of xylitol and erythritol on modulating blood glucose; inducing insulin secretion; reducing dyslipidemia and redox imbalance in a type 2 diabetes rat model
Published 2023-11-01“…The data of this study suggest that xylitol has better antioxidant and antidiabetic effects compared to erythritol. …”
Get full text
Article -
3987
Tumor microenvironment-responsive engineered hybrid nanomedicine for photodynamic-immunotherapy via multi-pronged amplification of reactive oxygen species
Published 2025-01-01“…Abstract Reactive oxygen species (ROS) is promising in cancer therapy by accelerating tumor cell death, whose therapeutic efficacy, however, is greatly limited by the hypoxia in the tumor microenvironment (TME) and the antioxidant defense. Amplification of oxidative stress has been successfully employed for tumor therapy, but the interactions between cancer cells and the other factors of TME usually lead to inadequate tumor treatments. …”
Get full text
Article -
3988
Effects of nanocurcumin supplementation on metabolic syndrome: A systematic review and meta-analysis of randomized controlled trials
Published 2025-03-01“…Improvement in diastolic blood pressure (DBP) (SMD: −0.32 mmHg), total antioxidant capacity (TAC) (SMD: 0.44 mmol/L), malondialdehyde (MDA) (SMD: −0.37 mmol/L), tumor necrosis factor-α (TNF-α) (SMD: −2.30 ng/L), interleukin-6 (IL-6) (SMD: −1.07 ng/L), and high-sensitivity C-reactive protein (hs-CRP) (SMD: −0.34 mg/L) were observed. …”
Get full text
Article -
3989
IRG1/itaconate enhances efferocytosis by activating Nrf2-TIM4 signaling pathway to alleviate con A induced autoimmune liver injury
Published 2025-02-01“…IRG1 and its metabolites play important roles in infection, immune-related diseases and tumor progression by exerting resistance of pathogens, attenuating inflammation and producing antioxidant substances through various pathways and mechanisms. …”
Get full text
Article -
3990
Levying evidence of the impact of Triphala in the mildly constipated human colon microbiota
Published 2025-02-01“…Metabolic profiling of Triphala treatment showed increased phenolic species and antioxidant potential and reduced ammonia, valeric, isovaleric, and isobutyric acids during fermentation, potentially benefiting intestinal health, especially in contexts of constipation. …”
Get full text
Article -
3991
Growth Performance, Serum Biochemical Profile, Oxidative Status, and Fertility Traits in Male Japanese Quail Fed on Ginger (Zingiber officinale, Roscoe) Essential Oil
Published 2018-01-01“…The serum content in total protein and globulin and the antioxidant enzymes activities increased in treated birds compared to the control. …”
Get full text
Article -
3992
Gallic acid protects intervertebral disc cells from ferroptosis and alleviates intervertebral disc degeneration by regulating key factors of oxidative stress
Published 2025-02-01“…Gallic acid (GA) is naturally present in a variety of plants and has anti-inflammatory, antioxidant and analgesic effects. It has been shown to alleviate ferroptosis. …”
Get full text
Article -
3993
Gastroprotective Value of Berries: Evidences from Methanolic Extracts of Morus nigra and Rubus niveus Fruits
Published 2017-01-01“…Interestingly, MERN decreased the ulcer area in a superior potency (ED50 = 20.88 mg/kg), reducing the ulcer area by 81.86% at 300 mg/kg, and increased the gastric mucin levels. The antioxidant effects of extracts were evidenced by reduced lipoperoxides and increased reduction of glutathione amount in the gastric mucosa. …”
Get full text
Article -
3994
The Impact of Grape Maceration on Quality and Biogenic Amine Formation in Slovak Tokaj Wines: Examination of Microbial, Chemical and Sensory Properties
Published 2025-01-01“…The formation of bioactive components in wine was affected by maceration and maceration with the addition of a yeast culture, which resulted in a significantly increased antioxidant activity, as well as total phenolic and flavonoid content (<i>p</i> < 0.001). …”
Get full text
Article -
3995
Assessing the effects of drought stress on photosynthetic performance and physiological resistance in camphor seedling leaves.
Published 2025-01-01“…Furthermore, parameters such as PIABS (Performance Index based on absorbed light energy), WK (the ratio of variable fluorescence FK at the K point to the amplitude FO-FJ), VJ (the ratio of variable fluorescence FJ at the J point to the amplitude FO-FP), ΔI/I0 (the relative amplitude of the 820 nm light absorption curve), superoxide dismutase (SOD), peroxidase (POD), catalase (CAT), and malondialdehyde (MDA) were measured to evaluate the impact of drought stress on various physiological processes and antioxidant enzyme activities. Results showed significant decreases in base diameter growth (GD) and seedling height growth (GH) with increasing drought stress. …”
Get full text
Article -
3996
Effects of Different Cooking Methods on the Contents and Activities of Active Substances in Shiitake Mushroom Digested in Vitro in Simulated Gastrointestinal Juices
Published 2025-01-01“…The contents of total phenols, total flavonoids, crude polysaccharide and eritadenine in steamed, boiled, air fried, or roasted mushroom digested in vitro in simulated gastrointestinal juices were determined, as well as their in vitro antioxidant, hypolipidemic and hypoglycemic activities. …”
Get full text
Article -
3997
Terminal complement complex deposition on chondrocytes promotes premature senescence in age- and trauma-related osteoarthritis
Published 2025-01-01“…In human cartilage, trauma and subsequent stimulation with HS increased mRNA levels of CDKN1A, CDKN2A, and IL6, while inhibition of TCC formation by CLU reduced the expression. Antioxidative therapy with NAC had no anti-senescent effect. …”
Get full text
Article -
3998
Associations between oxidation balance score and abdominal aortic calcification, and the mediating role of glycohemoglobin: a nationally representative cross-sectional study from N...
Published 2025-01-01“…Our aim was to evaluate whether subjective interventions could influence AAC scores by modifying the antioxidant/pro-oxidant status of individuals and to investigate the role of glycohemoglobin in this relationship.MethodsThe study analyzed data from 1,600 U.S. adults. …”
Get full text
Article -
3999
Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington’s Disease
Published 2018-01-01“…This study investigated whether chronic administration of the antioxidant probucol improved motor and affective symptoms as well as hippocampal neurogenic function in the YAC128 transgenic mouse model of HD during the early- to mild-symptomatic stages of disease progression. …”
Get full text
Article -
4000
Phytochemical and Metabolomic Profiles of Ethanolic Extract of Curculigo pilosa Rhizomes for Animal Health
Published 2024-11-01“…Some of the phytocompounds identified in this study are biologically important and exhibit antimicrobial, antioxidant, and anti-inflammatory properties, which may hold therapeutic potential for both animal and human health.…”
Get full text
Article