Effects of Fishmeal Substitution with Mealworm Meals (Tenebrio molitor and Alphitobius diaperinus) on the Growth, Physiobiochemical Response, Digesta Microbiome, and Immune Genes E... by H-Michael Habte-Tsion, Matt Hawkyard, Wendy M. Sealey, David Bradshaw, Kala-Mallik Meesala, Deborah A. Bouchard

“…Plasma parameters (total protein, alanine aminotransferase, alkaline phosphatase, and total iron-binding capacity), hepatic peroxide, and antioxidant enzymes were not significantly affected by dietary substitutions, whereas plasma immunoglobulin M showed significantly higher levels in fish fed 50% DMM and 100% DMM when compared to fish fed the control diet (100% FM). …”
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Hake Fish Preservation Using Plant-Based Impregnated Polylactic Acid Food Films as Active Packaging by Fini Sánchez-García, Noelia D. Machado, María Tirado-Fernández, Cristina Cejudo-Bastante, Ana M. Roldán, Casimiro Mantell-Serrano, Lourdes Casas-Cardoso

“…The ABTS assay was used to determine the antioxidant activity, and migration tests were performed using food simulants A and D2 for 10 days at 5 °C. …”
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Ethanolic extract of Dayak onion (Eleutherine palmifolia) prevented sperm membran damage in mice exposed to monosodium glutamate by Syahraini Adhiya Lathifah, Aldin Akbar Rahmatullah, Boedi Setiawan, Chairul Anwar Nidom, Nove Hidajati, Sri Mulyati, Tri Wahyu Suprayogi

“…Dayak onion extract which is known for its high antioxidant content, could help alleviate oxidative stress caused by MSG. …”
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Snack products from whole-grain red sorghum flour with paprika and cocoa powders by Janić-Hajnal Elizabet, Banjac Vojislav, Filipčev Bojana, Radić Bojana, Kos Jovana, Šimurina Olivera, Cvetković Biljana

“…Rich in macronutrients (proteins, fats, and carbohydrates) and micronutrients (minerals, vitamins), sorghum also contains phenolic compounds (tannins, phenolic acids, and flavonoids), which have antioxidant properties. Given its many health benefits, including its ability to suppress the formation of cancer cells and reduce obesity, heart disease, and diabetes, sorghum is used for both human and animal consumption. …”
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Integrated Transcriptomic and Targeted Metabolomic Analysis Reveals the Key Genes Involved in Triterpenoid Biosynthesis of <i>Ganoderma lucidum</i> by Xiaolan Xu, Chunxia Li, Fangjing Wu, Shuangshuang Zhao, Tiqiang Chen, Haihong You, Yijie Lin, Xiaoxing Zou

“…These compounds have various pharmacological functions, including anti-tumor, antioxidant, anti-inflammatory, liver-protective, and immune-regulating effects. …”
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Hydrogen-Rich Saline Attenuates Acute Renal Injury in Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting ROS and NF-κB Pathway by Qiao Shi, Kang-Shu Liao, Kai-Liang Zhao, Wei-Xing Wang, Teng Zuo, Wen-Hong Deng, Chen Chen, Jia Yu, Wen-Yi Guo, Xiao-Bo He, Ablikim Abliz, Peng Wang, Liang Zhao

“…Hydrogen (H2), a new antioxidant, was reported to reduce •OH and ONOO− selectively and inhibit certain proinflammatory mediators to product, without disturbing metabolic redox reactions or ROS involved in cell signaling. …”
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Effects of melatonin supplementation on oxidative stress, and inflammatory biomarkers in diabetic patients with chronic kidney disease: a double-blind, randomized controlled trial by Sara Sadeghi, Amirahmad Nassiri, Monir Sadat Hakemi, Fatemeh Hosseini, Fatemeh Pourrezagholie, Fatemeh Naeini, Aylar Nadiri Niri, Hossein Imani, Hamed Mohammadi

“…It has been demonstrated that the natural antioxidant melatonin reduces inflammation and oxidative damage in renal tissues. …”
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Comparative effects of different dietary pectin types on growth performance and intestinal health in pearl gentian grouper (Epinephelus fuscoguttatus♀ × E. lanceolatus♂) by Lulu Zhu, Xiaoxue Meng, Xuehan Wang, Jiongting Fan, Beiping Tan, Junming Deng

“…The various type of pectin decreased the intestinal lipase activity and plasma lipopolysaccharide level, increased the intestinal total antioxidant capacity, and down-regulated the expression of intestinal TNF-α and IL-8 but up-regulated the expression of intestinal IL-10. …”
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Adaptive evolution of stress response genes in parasites aligns with host niche diversity by Armando J. Cruz-Laufer, Maarten P. M. Vanhove, Lutz Bachmann, Maxwell Barson, Hassan Bassirou, Arnold R. Bitja Nyom, Mare Geraerts, Christoph Hahn, Tine Huyse, Gyrhaiss Kapepula Kasembele, Samuel Njom, Philipp Resl, Karen Smeets, Nikol Kmentová

“…We comparatively investigated antioxidant, heat shock, osmoregulatory, and behaviour-related genes (foraging) in two model parasitic flatworm lineages with contrasting ecological diversity, Cichlidogyrus and Kapentagyrus (Platyhelminthes: Monopisthocotyla), through whole-genome sequencing of 11 species followed by in silico exon bait capture as well as phylogenetic and codon analyses. …”
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Improving the physiological status of broiler chickens using rosemary leaf meal and sodium bentonite as ammonia gas control agents by Mercy Chisara Ogwuegbu, Fredrick Ugochukwu Udeh, Josephine Chinenye Ugwuozor, Precious Ezinne Okoye, Joy Chimela Kalu, Emmanuel Chinonso Arum, Doctor Mziwenkosi Nhlanhla Mthiyane

“…Broilers fed 6 g RLM + 15 g SB/kg diet exhibited significantly (P < 0.05) enhanced antioxidant enzyme activities (superoxide dismutase, catalase, glutathione peroxidase and glutathione reductase), reduced malondialdehyde and cholesterol levels, and improved mineral composition (potassium, calcium, magnesium, zinc, iron, and phosphorus). …”
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Design of Bacterial Cultures in Fermented Functional Maize Product Formulation by Zuzana Matejčeková, Anna Mikulajová, Eva Vlková, Denisa Liptáková, Silvia Mošovská, Eva Hybenová, Ľubomír Valík

“…Fermentation process was observed to significantly increase (p<0.05) the total phenolics content (143.9-206.1%) and the antioxidant activities (53.7-107.4%) of the samples. …”
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Identification of <i>ZmSNAC06</i>, a Maize NAC Family Transcription Factor with Multiple Transcripts Conferring Drought Tolerance in <i>Arabidopsis</i> by Fei Wang, Yong Chen, Ruisi Yang, Ping Luo, Houwen Wang, Runze Zhang, Wenzhe Li, Ke Yang, Xinlong Xu, Zhuanfang Hao, Xinhai Li

“…The overexpression of <i>ZmSNAC06</i>-T02 in <i>Arabidopsis</i> resulted in hypersensitivity to abscisic acid (ABA) at the germination stage, and overexpression lines exhibited higher survival rates and higher antioxidant enzyme activities compared with the wild-type under drought stress. …”
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Hepatoprotective Effects of a Novel Trihoney against Nonalcoholic Fatty Liver Disease: A Comparative Study with Atorvastatin by Hamad Abdulsalam Hamad Alfarisi, Muhammad Bin Ibrahim, Zenab B. Hamad Mohamed, Nuraniza Azahari, Asmah Hanim Bt. Hamdan, Che Anuar Che Mohamad

“…Trihoney was able to maintain normal liver function and showed hepatoprotection against progression of NAFLD to NASH probably through hypocholesterolaemic and antioxidant functions.…”
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Mechanism of <italic>Hindu Datura</italic> in the Treatment of Rheumatoid Arthritis from the Perspective of Network Pharmacology by Changlong FU, Yangyang MEI, Xihai LI, Zhiwei QIU, Changxing CHEN, Chunsong ZHENG

“…Objective:To construct the active component target of <italic>Hindu datura</italic> and the disease target of rheumatoid arthritis by using network pharmacology, to predict the specific molecular signal and pathway of <italic>hindu datura</italic> in the treatment of rheumatoid arthritis, and to analyze its potential therapeutic target and molecular mechanism.Methods:All the chemical components of <italic>hindu datura</italic> were summarized and screened through Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP)database, retrieval was performed with the preset oral bioavailability(OB)≥30%and drug like(DL)≥0.18.Uniprot database was used to screen the entire correlation basis of the effective chemical compound.After screening the disease target with"rheumatoid arthritis"as the retrieval word using GeneCards and OMIM database, the superimposed target area between the drug target of <italic>hindu datura</italic> and the disease target of rheumatoid arthritis was summarized and analyzed, and it could be used as the prediction target gene of <italic>hindu datura</italic> for treating rheumatoid arthritis.Network targets were constructed and analyzed for the exported data based on Cytoscape 3.7.1 software and STRING 7.8 database.Finally, GO functional enrichment analysis and KEGG signal pathway analysis were performed to further screen the main targets and signal pathways.Results:①Through screening and analysis, 27 effective compounds, 318 corresponding target genes and 125 predicted target genes were obtained for the treatment of rheumatoid arthritis.②The core genes in PPI network mainly included JUN, AKT1, RELA, MAPK1, etc.③GO functional enrichment analysis showed that the biological process(BP)for the treatment of rheumatoid arthritis by <italic>hindu datura</italic> mainly involves response to lipopolysaccharide, response to lipopolysaccharide, response to molecule of bacterial origin, response to metalion, response to oxidative stress, response to steroid hormone, cellular response to oxidative stress, reactive oxygen species metabolic process, response to oxygen levels, etc..The cell component(CC)consisted of membrane raft, membrane region, plasma membrane raft and presynaptic membrane; molecular functions(MF)mainly involved the nuclear receptor activity, transcription factor activity(direct ligand regulated sequence-specific DNA binding), steroid hormone receptor activity, cytokine receptors, cytokine activity, DNA-binding transcription activator activity, RNA polymeraseⅡtranscription factor binding, kinase regulator activity, receptor ligand activity, etc.The analysis of KEGG signaling pathway showed that the obvious pathway of <italic>hindu datura</italic> in the treatment of rheumatoid arthritis may involve IL-17 signaling pathway, TNF signal pathway, HIF-1signalpathway, Toll-like receptor signal pathway, etc.Conclusion:The potential mechanism of <italic>hindu datura</italic> for the treatment of rheumatoid arthritis is to exert anti-inflammatory, analgesic and antioxidant effects, which involve a number of interactive signal pathways.…”
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Benzothiazole (BTH) Induced Resistance of Navel Orange Fruit and Maintained Fruit Quality during Storage by Huaying Du, Ying Sun, Rui Yang, Wei Zhang, Chunpeng Wan, Jinyin Chen, İbrahim Kahramanoğlu, Liqin Zhu

“…BTH treatment significantly enhanced antioxidant capacity (DPPH, ABTS radical scavenging activity, and reducing power), and superoxide dismutase (SOD) and peroxidase (POD) activities were significantly increased, while the activity of catalase (CAT) was opposite to the former (P<0.05). …”
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The Isolation of Lead-Tolerant PGPR from Red Clover Soil and Its Role in Promoting the Growth of Alfalfa by Wanting Nie, Yuchen Wu, Jingwen Jiang, Zicheng Wang, Meiqi Mu, Siwen Zhao, Minghao Yang, Xi Long, Xiujie Yin, Xiaohua Teng

“…They could all significantly raise the chlorophyll content and antioxidant enzyme activity in alfalfa (<i>p</i> < 0.05) and the content of malondialdehyde (MDA) in alfalfa. …”
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Dietary supplementation with sodium humate improves egg quality and immune function of laying hens by A.R. Zhang, S.A. Pirzado, G.H. Liu, Z.M. Chen, W.H. Chang, H.Y. Cai, W.L. Bryden, A.J. Zheng

“…Egg production, egg quality, serum antioxidant parameters and immunity indexes were measured. …”
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Network pharmacology and experimental verification to investigate the mechanism of isoliquiritigenin for the treatment of Alzheimer’s disease by Waimao Gao, Guang Yang, Xinjuan Liu, Kaifan Hu, Jie Pan, Xingyu Wang, Yan Zhao, Ying Xu

“…Abstract Isoliquiritigenin (ISL), a flavone isolated from licorice, has been demonstrated to exhibit anti-inflammatory and antioxidant properties in the treatment of Alzheimer’s disease (AD). …”
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The activity of a herbal medicinal product of Phyllanthus niruri and Silybum marianum powdered extracts (Heptex®) in patients with apparent risk factors for nonalcoholic steatohepa... by Mohamed Kamal Shaker, Mohamed Hassany, Basem Eysa, AbdulMoneim Adel, Ahmed Zidan, Shahnaz Mohamed

“…Some medicinal plants have shown antioxidant and anti-inflammatory effects on liver cells. …”
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Detection Methods for Asparagine and Glutamine Contents in Fruits and Vegetables and Recommendations for Dietary Intake of Fruits and Vegetables in Patients with Urea Cycle Disorde... by YE Xinyu, LI Ziying, TANG Shujun, SUN Liping, ZHAO Yunxia, XIAO Weimin, GU Yaping, KUANG Huiying, CHEN Xin, YANG Guowu, HUANG Yali

“…After enzymatic hydrolysis with Pronase E, samples were treated with butylated hydroxyanisole as an antioxidant. The supernatant was collected for analysis by UPLC-MS/MS. …”
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