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3881
Combined metabolomic and transcriptomic analysis to reveal the response of rice to Mn toxicity stress
Published 2025-01-01“…Transcriptome analysis identified differentially expressed genes associated with transcription factors, antioxidant enzymes, and metal transporters. Metabolomics revealed 176 and 214 different metabolites in the roots and leaves, respectively, that under Mn toxicity stress affected major metabolic pathways associated with fatty and amino acids. …”
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3882
Cell-free fat extract improves embryo development and clinical outcomes in older women with previous in-vitro fertilization failure
Published 2025-01-01“…Cell-free fat extract exerts antioxidant, anti-ageing, and ovarian function-promoting effects. …”
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3883
Simultaneous exposure to microplastics and heavy metal lead induces oxidative stress, histopathological damage, and immune dysfunction in marine mussel Mytilus coruscus
Published 2025-01-01“…In addition, co-exposure induced a higher level of oxidative stress, which was reflected by an increase in hydrogen peroxide and malondialdehyde content, and a decrease in antioxidant enzyme activity. Meanwhile, co-exposure poses a significant threat to the immune function of the mussels, as evidenced by induction of hemocytes to produce excess reactive oxygen species (ROS), significantly reducing lysosome activity (p < 0.05), inhibiting the expression of autophagy-related genes, and inducing the expression of apoptosis-related genes, resulting in hemocyte apoptosis. …”
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3884
Dietary carotenoid intakes and biological aging among US adults, NHANES 1999–2018
Published 2025-01-01“…Abstract Background Carotenoids have been shown to have multiple health benefits, including antioxidant and anti-inflammatory. The data for the effect of dietary specific carotenoids on biological aging is limited. …”
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3885
Butterfly Pea and Roselle Combination Extracts Reduce V-CAM, ICAM, and IL-6 Levels in High Fat Atherogenic Diet Rats
Published 2024-12-01“…Flavonoids in butterfly pea and roselle are known for their potent antioxidant and anti-inflammatory properties. While their individual effects on cardiovascular health have been studied, no studies have explored the combined impact on atherosclerosis biomarkers, including vascular cell adhesion molecules (VCAM)-1, intercellular adhesion molecule (ICAM)-1, and interleukin (IL)-6. …”
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3886
Chitosan oligosaccharide alleviates DON-induced liver injury via suppressing ferroptosis in mice
Published 2025-01-01“…Moreover, COS significantly reduced liver reactive oxygen species (ROS) levels, malondialdehyde (MDA) content, and lactate dehydrogenase (LDH) release in DON-exposed mice, while restoring the activity of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) and total antioxidant capacity (T-AOC). Further investigations revealed that COS modulated the expressions of pro-inflammatory cytokines and anti-apoptotic proteins through stimulation of the Nrf2/HO-1 signaling pathway and suppression of the NF-κB signaling pathway. …”
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3887
Inverse relationship of oxidative balance score with hyperuricemia among Chinese adults: a population-based cross-sectional study
Published 2025-01-01“…Abstract Background The oxidative balance score (OBS) is a composite metric highlights pro-oxidants and antioxidants balance, representing the overall burden of oxidative stress. …”
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3888
Peroxiredoxin 6 Attenuates Alloxan-Induced Type 1 Diabetes Mellitus in Mice and Cytokine-Induced Cytotoxicity in RIN-m5F Beta Cells
Published 2020-01-01“…We hypothesised that PRDX6, which is well known for its various biological functions, including antioxidant activity, may provide an antidiabetic effect. …”
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3889
Effects of microbial fermentation on the anti-inflammatory activity of Chinese yam polysaccharides
Published 2025-01-01“…Meanwhile, the molecular weight and polydispersity of CYP-LP, respectively, increased from 124.774 kDa and 6.58 (CYP-NF) to 376.628 kDa and 17.928, indicating a low homogeneity. In vitro antioxidant analysis showed that L. plantarum M616 fermentation had varying effects on CYP-LP against DPPH, ABTS, hydroxyl, and superoxide radicals. …”
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3890
Maternal milk fat globule membrane enriched gut L. murinus and circulating SCFAs to improve placental efficiency and fetal development in intrauterine growth restricted mice model
Published 2025-12-01“…Meanwhile, MFGM supplementation during gestation enriched intestinal Lactobacillus murinus (L. murinus) and increased luminal and circulating short chain fatty acids (SCFAs) in IUGR pregnant mice, which improved placental efficiency and fetal development due to an enhanced antioxidant capacity and a decreased inflammation. In addition, fecal microbiota transplantation (FMT) with MFGM-derived microbiota reprinted the promoted phenotypes of maternal litter characteristics, gut L. murinus enrichment, placental efficiency, and fetal gut development in MFGM-fed pregnant mice, which were also recapitulated by exogenous administration with L. murinus or SCFAs cocktail. …”
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3891
Untargeted Metabolomics Reveals Key Differences Between Yak, Buffalo, and Cow Colostrum Based on UHPLC-ESI-MS/MS
Published 2025-01-01“…Conclusions: YC has greater advantages in energy supply, antioxidant activity, immune regulation, and cell homeostasis, and BC holds unique significance in physical development and energy balance regulation. …”
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3892
Dietary glycemic and insulin indices with the risk of osteoporosis: results from the Iranian teachers cohort study
Published 2025-01-01“…Moreover, higher DIL and DGL were associated with a higher intake of calorie-dense/nutrient-poor foods and a lower intake of antioxidant-rich foods.ConclusionAlthough our study showed that high DGI/DGL increased osteoporosis risk in Iranian teachers, no association was found between DII/DIL and osteoporosis prevalence. …”
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3893
Comprehensive identification, characterization and expression analyses of the class III POD gene family in water lily (Nymphaea colorata)
Published 2025-01-01“…These findings provide valuable insights for future exploration of NcPOD functions in water lily growth and stress tolerance, laying a foundation for further comparative genomics and functional studies of this important class of antioxidant genes.…”
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3894
Black Trumpet, Craterellus cornucopioides (L.) Pers.: Culinary Mushroom with Angiotensin Converting Enzyme Inhibitory and Cytotoxic Activity
Published 2022-06-01“…Nutritional value and chemical composition, including the content of vitamins, fatty acids, 5’-nucleotides and nucleosides and amino acids, as well as biological activities, including antioxidant, angiotensin converting enzyme (ACE) inhibitory and cytotoxic activity of black trumpet ( Craterellus cornucopioides (L.) …”
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3895
The dipeptide carnosine alleviates acute pancreatitis in an experimental model
Published 2024-12-01“…Carnosine is an endogenous dipeptide with various pharmacological effects, including antioxidative and anti-inflammatory properties. The current study was designed to evaluate the impact of carnosine in an experimental model of AP. …”
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3896
The Hydroalcoholic Extract Obtained from Mentha piperita L. Leaves Attenuates Oxidative Stress and Improves Survival in Lipopolysaccharide-Treated Macrophages
Published 2017-01-01“…Overall, the LHAE obtained from peppermint modulates macrophage-mediated inflammatory responses, by stimulating the antioxidant pathway in these cells. These effects may be beneficial when the excessive activation of macrophages contributes to tissue damage during infectious disease.…”
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3897
Variation in Nutritional Quality of By-Products from Nine Organic Apple Cultivars
Published 2024-01-01“…The total content of polyphenols, antioxidant activity, ascorbic acid (vitamin C) and phenolic content were determined in nine apple varieties from two harvest years (2020 and 2021) during 9 months of storage. …”
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3898
The Influence of Ficus deltoidea in Preserving Alveolar Bone in Ovariectomized Rats
Published 2020-01-01“…Ficus deltoidea has been shown to possess antioxidant properties that could prevent the development of chronic inflammatory bone diseases. …”
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3899
Park7 deletion leads to sex-specific transcriptome changes involving NRF2-CYP1B1 axis in mouse midbrain astrocytes
Published 2025-01-01“…The affected genes are involved in processes like focal adhesion, extracellular matrix interaction, and epithelial-to-mesenchymal transition (EMT), and enriched for primary target genes of NRF2. Consistently, the antioxidant response was altered specifically in the midbrain of male DJ-1 deficient mice. …”
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3900
The effect of probiotic-fortified kefir on depression, appetite, oxidative stress, and inflammatory parameters in Iranian overweight and obese elderly: a randomized, double-blind,...
Published 2025-02-01“…Moreover, a significant difference in the changes in total antioxidant capacity (TAC) was noted (p = 0.009). However, no significant differences were observed in other oxidative and inflammatory parameters between the two groups (p˃0.05 for all). …”
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