The Safety and Tolerability of 5-Aminolevulinic Acid Phosphate with Sodium Ferrous Citrate in Patients with Type 2 Diabetes Mellitus in Bahrain by Feryal Al-Saber, Waleed Aldosari, Mariam Alselaiti, Hesham Khalfan, Ahmed Kaladari, Ghulam Khan, George Harb, Riyadh Rehani, Sizuka Kudo, Aya Koda, Tohru Tanaka, Motowo Nakajima, Abdulla Darwish

“…A multifaceted treatment approach can include nutritional supplements with antioxidant properties such as 5-aminolevulinic acid (5-ALA) with sodium ferrous citrate (SFC). …”
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Lysine Reacts with Cholesterol Hydroperoxide to Form Secosterol Aldehydes and Lysine-Secosterol Aldehyde Adducts by George Wafula Wanjala, Arnold Nola Onyango, David Rasugu Abuga, John Kamathi Muchuna, Calvin Onyango, Moses Makayoto

“…Here, we subjected cholesterol to photosensitized oxidation, which predominantly produces Ch-5α-OOH and minor amounts of the 6α- and 6β-hydroperoxides, exposed the hydroperoxide mixture to lysine in the presence of the antioxidant 2,6-ditertiary-butyl-4-hydroxytoluene (BHT), and analysed the reaction mixture by liquid chromatography-electrospray ionization-mass spectrometry. …”
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Antiamnesic and Neurotrophic Effects of Parkia biglobosa (Jacq.) R. Br (Fabaceae) Aqueous Extract on In Vivo and In Vitro Models of Excitotoxicity by Antoine Kavaye Kandeda, Liliane Yimta Foutse, Corneille Tongoue, Jean Philippe Djientcheu, Théophile Dimo

“…These effects seem to be mediated by antioxidant and anti-inflammatory modulations.…”
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Vitamin A family suppresses periodontitis by restoring mitochondrial metabolic reprogramming in macrophages through JAK-STAT pathway by Zishuo Cheng, Shun Huang, Qiya Tang, Danlan Zhang, Lan Huang

“…ObjectiveMitochondrial metabolic reprogramming in macrophages is crucial in the development and progression of inflammation. Given vitamin A’s antioxidant properties and its therapeutic effects on inflammation, this study aims to elucidate how vitamin A influences mitochondrial metabolic reprogramming in inflammatory states, specifically in periodontitis, through genetic bioinformatics and experimental methods.MethodThe study utilized the GSE16134 dataset from the Gene Expression Omnibus (GEO) database, focusing on human periodontitis. …”
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Inhibition of RAD51 by siRNA and Resveratrol Sensitizes Cancer Stem Cells Derived from HeLa Cell Cultures to Apoptosis by Graciela Ruíz, Heriberto A. Valencia-González, Ismael León-Galicia, Enrique García-Villa, Alejandro García-Carrancá, Patricio Gariglio

“…RESveratrol (RES), a natural compound, is an antioxidant with multiple beneficial activities. We previously determined that the expression of RAD51 is decreased by RES. …”
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Pterostilbene antagonizes homocysteine-induced oxidative stress, apoptosis and lipid deposition in vascular endothelial cells by Qiao Jiang, Li Wang, Xu Si, Yuanyuan Bian, Weijia Zhang, Huijun Cui, Hailong Gui, Ye Zhang, Bin Li, Dehong Tan

“…Pterostilbene (Pte) has been reported to have antioxidant and anti-apoptotic effects under various pathological conditions. …”
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A comprehensive assessment of source material for apple breeding for immunity and fruit quality by E. V. Ulyanovskaya, T. G. Prichko, L. D. Chalaya

“….), the quality and marketability of fruits, the content of biologically active substances underlying the antioxidant  properties of fruits. An advanced method of polyploidy based on inclusion of parental forms with immunity to scab was applied in Apple selection. …”
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Nostoc commune Vauch. polysaccharide alleviates Pb-induced hepatorenal toxicity by changing gut bacteriome, mycobiome, and metabolome by Yue Liu, Ping Ren, Hailong Li, Yingying Liu, Yiting Yang, Wanting Wang, Jiaming Zhou, Ling Su, Lili Guan, Hongxia Ma

“…NCVP improved Pb-induced hepatorenal toxicity and inflammatory responses and modulated key indicators of antioxidant capacity. Moreover, the down-regulation of critical proteins of the Nrf2 pathway induced by Pb could be reversed after NCVP intervention. …”
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Modified citrus pectin ameliorates methotrexate-induced hepatic and pulmonary toxicity: role of Nrf2, galectin-3/TLR-4/NF-κB/TNF-α and TGF-β signaling pathways by Randa Ismail, Heba A. Habib, Aliaa F. Anter, Amr Amin, Gehan H. Heeba

“…MCP enhanced the cytotoxicity of MTX in Nalm6 and JEG3 and did not interfere with its cytotoxicity in the MCF7 cell lines.DiscussionMCP attenuated MTX-induced liver and lung toxicity through antioxidant, anti-fibrotic, anti-inflammatory, and anti-apoptotic influences, as demonstrated by the improved histopathological changes induced by MTX in pulmonary and hepatic tissues. …”
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Use of Coffee Silverskin and Stevia to Improve the Formulation of Biscuits by Garcia-Serna Esther, Martinez-Saez Nuria, Mesias Marta, Morales Francisco J., Castillo M. Dolores del

“…The quality and safety of the innovative biscuits was obtained by an analysis of the sugars, proteins, free amino acids, chlorogenic acid, overall antioxidant capacity and acrylamide after in vitro digestion. …”
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Global hotspots and trends of nutritional supplements for sick populations from 2000 to 2024 by Chaofan Shi, Haitao Liu, Haitao Liu, Haitao Liu, Te Fu, Yuanquan Li, Haichang Zhao, Feiyue Liu

“…Research focuses on dietary supplementation, oxidative stress, in vitro injections, development, antioxidant activity, double-blind trials, lipid supplements, functional foods, the health of diseased populations, and the risks of NS.ConclusionDifferent supplements each possess unique benefits and should be chosen according to the type of disease to ensure they contain the corresponding nutrients. …”
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Synthesis, Characterization, Cyclic Voltammetry, and Biological Studies of Co(II), Ni(II), and Cu(II) Complexes of a Tridentate Schiff Base, 1-((E)-(2-Mercaptophenylimino) Methyl)... by Maurice Kuate, Mariam Asseng Conde, Evans Ngandung Mainsah, Awawou G. Paboudam, Francis Merlin M. Tchieno, Kevin I. Y. Ketchemen, Ignas Tonle Kenfack, Peter T. Ndifon

“…In vitro antibacterial and antifungal activity against five bacterial strains (Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Enterococcus faecalis, and Proteus mirabilis) and five fungal strains (Candida albicans, Candida glabrata, Candida tropicalis, Candida krusei, and Candida parapsilosis) showed no antifungal activity but moderate antibacterial activity on E. coli, S. aureus, P. aeruginosa, and P. mirabilis bacterial strains. Antioxidant studies reveal that the ligand and its Cu(II) complex are more potent than Co(II) and Ni(II) complexes to eliminate free radicals.…”
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The Association of Plasma Selenium and Selenoprotein P Levels with Depression Severity and Anxiety Symptoms Among Medical Students in Latvia by Zanda Birģele, Paula Marija Vimba, Anastasija Ševčenko, Andrejs Šķesters, Gunta Ancāne, Laura Valaine

“…Selenium is incorporated into antioxidant selenoproteins, such as selenoprotein P, which acts as the main selenium-transport protein in plasma and as an extracellular oxidant defense mechanism. …”
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Squalene Extraction by Supercritical Fluids from Traditionally Puffed Amaranthus hypochondriacus Seeds by Teresa Rosales-García, Cristian Jiménez-Martínez, Anaberta Cardador-Martínez, Sandra Teresita Martín-del Campo, Luis A. Galicia-Luna, Dario Iker Téllez-Medina, Gloria Dávila-Ortiz

“…Extraction of squalene, a potent natural antioxidant, from puffed A. hypochondriacus seeds was performed by supercritical fluid extraction (SCFE); besides, to have a blank for comparison, extraction was performed also by Soxhlet method using organic solvents (hexane). …”
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Serine Deficiency Exacerbates Inflammation and Oxidative Stress via Microbiota-Gut-Brain Axis in D-Galactose-Induced Aging Mice by Fengen Wang, Hongbin Zhou, Ligang Deng, Lei Wang, Jingqing Chen, Xihong Zhou

“…Since serine availability plays important roles in the support of antioxidant and anti-inflammatory defense system, we explored whether serine deficiency affects inflammatory and oxidative status in D-galactose-induced aging mice. …”
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The association between oxidative balance score with constipation and diarrhea in US adults: a cross-sectional analysis of NHANES 2007–2010 by Yaoling Cao, Zhihao Yang, Qinqing Tang

“…These findings suggest that antioxidant-rich dietary modifications may be an effective strategy for preventing constipation in males and diarrhea in females.…”
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Glutathione-dependent system in the blood of gastric cancer patients with various tumor histotypes and prevalence of the disease by I. A. Goroshinskaya, E. I. Surikova, E. M. Frantsiyants, L. A. Nemashkalova, P. S. Kachesova, D. E. Medvedeva, A. A. Maslov

“…The activity of the antioxidant enzymes glutathione peroxidase and glutathione transferase was increased in all groups, and especially in SRCC - by 76 % and 23-29 %, respectively. …”
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Gallic acid: a dietary metabolite’s therapeutic potential in the management of atherosclerotic cardiovascular disease by Xiao-Lan Zhao, Zhang-Jing Cao, Ke-Di Li, Fei Tang, Li-Yue Xu, Jing-Nan Zhang, Dong Liu, Cheng Peng, Hui Ao, Hui Ao

“…Gallic acid (GA), a natural secondary metabolite found in various fruits, plants, and nuts, has demonstrated potentials in preventing and treating ASCVD, in addition to its known antioxidant and anti-inflammatory effects. It alleviates the entire process of atherosclerosis (AS) by reducing oxidative stress, improving endothelial dysfunction, and inhibiting platelet activation and aggregation. …”
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Effects of Pristane Alone or Combined with Chloroquine on Macrophage Activation, Oxidative Stress, and Th1/Th2 Skewness by Qiufang Ouyang, Ziyang Huang, Zhenhua Wang, Xiaoqing Chen, Jingqin Ni, Ling Lin

“…Hematological and biochemical parameters, macrophage phagocytic function, the oxidant/antioxidant index, cytokine for IFN-γ, TNF-α, IL-4, and IL-6, and the isotypes of IgG2a and IgG1 were determined. …”
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Determination of the physicochemical characteristics and bioactive compounds of the miracle fruit (Synsepalum dulcificum) considering different extraction and preservation methods by Juan Alejandro Neira Mosquera, Sungey Naynee Sánchez Llaguno, Karol Yannela Revilla Escobar, Jhonnatan Placido Aldas Morejon, Angie Estefania Iguasnia Ureta, Andy Sebastian Parrales Loor, Jonathan Alexander Arguello Cedeño

“…The maceration with fluid extract method achieved the most favorable results in terms of bioactive compounds, including flavonoids (20.14 mg Eq/g), anthocyanins (9.55 mg/g), total phenolic content (16.53 mg gallic acid/g), and antioxidant capacity (521.24 μg Trolox/g). Conversely, cold pressing combined with fluid extract was the most effective for carotenoid extraction (77.16 μg/g). …”
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