Supercritical fluid extraction and encapsulation of Rivas (Rheum ribes) flower: Principal component analysis (PCA) by Seyyed Ali Hoseini, Mohsen Vazifedoost, Bahareh Hajirostamloo, Zohreh Didar, Mohamad Mehdi Nematshahi

“…The extract bioactivity was as follows: antioxidant activity of 89.6 ± 1.39 %; total phenolic content of 306.19 ± 13.59 mg GAE/g; total flavonoid content of179.84 ± 5.77 mg QE/g and a comparable antimicrobial effect to synthetic antimicrobials against E. coli, L. monocytogenes, and A. fumigatus. …”
Get full text

Isovitexin targets SIRT3 to prevent steroid-induced osteonecrosis of the femoral head by modulating mitophagy-mediated ferroptosis by Yinuo Fan, Zhiwen Chen, Haixing Wang, Mengyu Jiang, Hongduo Lu, Yangwenxiang Wei, Yunhao Hu, Liang Mo, Yuhao Liu, Chi Zhou, Wei He, Zhenqiu Chen

“…Isovitexin has demonstrated antioxidant properties, but its therapeutic effects on GC-induced oxidative stress and SIONFH remain unexplored. …”
Get full text

L-selenomethionine inhibits small intestinal ferroptosis caused by ammonia exposure through regulating ROS-mediated iron metabolism by Xinxin Zhang, Lepeng Gu, Ying Chen, Tianqi Wang, Houjuan Xing

“…The results showed that ammonia exposure up-regulated the levels of iron, ROS, MDA, and LPO in the small intestinal tissue and the IPEC-J2 cell, down-regulated the activities of antioxidant enzymes and the content of GSH, inhibited the Nrf2 pathway, significantly altered the expression of ferroptosis (TFR-1, FPN-1, FTH1, SLC7A11, GPX4, ACSL4) and intestine tight junctions (Claudin-1, Occludin, ZO-1) genes. …”
Get full text

Pilot-Scale Enzymatic Conversion of Low Stability, High Free Fatty, Squid Oil to an Oxidatively Stable Astaxanthin-Rich Acylglyceride Oil Suitable for Nutritional Applications by Asavari Joshi, Brendan Holland, Moninder Sachar, Colin J. Barrow

“…Squid viscera, a byproduct of squid processing, contains oil rich in omega-3 fatty acids (up to 10% by mass) and the antioxidant astaxanthin. However, its high free fatty acid (FFA) content compromises stability. …”
Get full text

Protective Effects of Sanyar Prebiotic on Immunity and Tissue Changes of Common Carp (Cyprinus carpio) Exposed to CuSO4 Stress by Ramezan Rajani, Mohammad Farhangi, Hojjatallah Jafaryan, Hossein Adineh, Maryam Alizadeh

“…Prebiotics, as feed additives, can activate the antioxidant and immune systems of fish and significantly improve the survival of aquaculture animals in stressful conditions. …”
Get full text

In vitro investigating of anticancer activity of focuxanthin from marine brown seaweed species by M. Karkhane Yousefi, M. Seyed Hashtroudi, A. Mashinchian Moradi, A.R. Ghasempour

“…The aim of the current study was to evaluate anticancer activity of fucoxanthin which is the most important carotenoid found in the marine brown seaweeds and diatoms. fucoxanthin has many properties (antioxidant, antibacterial, anticancer, antiobesity, anti-inflammatory and etc.) due to its unique structure. …”
Get full text

An orally administered gold nanocluster with ROS scavenging for inflammatory bowel disease treatment by Fei Wang, Qianhui Li, Tingting Xu, Zhu Li, Yongxin Jiang, Yan Ma, Xiaohu Li, Wanni Wang, Haisheng Qian

“…Au25 NCs can eliminate ROS such as ABTS radicals, superoxide free radicals (•O2−), and hydroxyl free radicals (•OH), upregulate the expression level of antioxidant enzymes, inhibit the expression of proinflammatory cytokines, and finally interrupt the inflammatory circuit of IBD to achieve the effective prevention and delayed treatment of IBD. …”
Get full text

Podocyte-related biomarkers' role in evaluating renal toxic effects of silver nanoparticles with the possible ameliorative role of resveratrol in adult male albino rats by Eman El-Sayed Khayal, Mona G. Elhadidy, Sulaiman Mohammed Alnasser, Manal Mohammad Morsy, Azza I. Farag, Samah A. El-Nagdy

“…Ag NPs group displayed a reduction in kidney weight ( absolute and relative), excess in urinary levels of kidney injury molecule, neutrophil gelatinase-associated lipocalin, cystatin, and blood kidney biomarkers (creatinine, urea, and potassium), increases in oxidative stress markers with the reduction in antioxidant markers, and decreases in serum sirtuin 1(SIRT1) level. …”
Get full text

Therapeutic effects of NAC and CoQ10 on aluminium phosphide poisoning as an adjuvant therapy: A Pilot study by Maii Farag Henaidy, Maha Ghanem, Shehata Farag Shehata, Amal M. Shouair, Reda R. Mabrouk

“…There is some evidence showing that N-acetylcysteine (NAC) and coenzyme Q10 have antioxidant and cardioprotective effects. This study investigated a new approach for treating acute AlP poisoning by using NAC and Co-Q10 as adjuvant therapy. …”
Get full text

Wound healing potential of green synthesized silver nanoparticles of Glycyrrhiza glabra linn root extract: A preclinical study by Laxman S. Vijapur, Mallappa Shalavadi, Anita R. Desai, Jayadev N. Hiremath, Avinash S. Gudigennavar, Somlingesh L. Shidramshettar, Shreyanka R. Hiremath, Malleswara Rao Peram, Bharatesh S. Kittur

“…Background: The research emphasizes the eco-friendly and sustainable approach of nanoparticle synthesis, leveraging the medicinal properties inherent in Glycyrrhiza glabra extract, which is known for its antimicrobial, anti-inflammatory, and antioxidant properties. By combining the therapeutic potential of the plant extract with the wound-healing capabilities of silver nanoparticles, the study seeks to develop an innovative, biocompatible, and effective treatment for enhanced wound healing process in excision and incision rat model. …”
Get full text

Metabolite profile of Passiflora mollisima leaf using UHPLC-ESI-MS and its potential anxiolytic activity in mice by Carmen Luisa Marìn-Tello, Esmeralda Palacios-Briceño, Elio Castañeda-Marín, Damian Caldas-Aburto, Emer Castillo-Olivares, Alejandrina Llaure-Mora, Noé Costilla-Sánchez, Ricardo Diego Duarte Galhardo de Albuquerque, Jorge Vásquez-Kool, Mayar Ganoza-Yupanqui

“…Conclusion: The metabolites identified have biological activities, neuroprotective, antioxidant, anti-inflammatory, antibacterial, and anticancer effects. …”
Get full text

Biological properties of Moringa oleifera: A systematic review of the last decade [version 2; peer review: 2 approved, 1 approved with reservations] by Andrea Catalina Gómez, Javier Andrés Soto, C. A. Zuniga-Gonzalez, Karen Shirley Molina, Andrea Natalia Barreto, Maryeli Vásquez

“…Results Moringa oleifera extracts showed antioxidant, hypoglycemic, antihypertensive and cytoprotective properties at neuronal, hepatic, renal and cardiac levels. …”
Get full text

Quality Evaluation of Herbal Yoghurt Produced Using Cinnamon (Cinnamon cassia), Garlic (Allium sativum) and Ginger (Zingiber officinale) by Ifeoma Elizabeth Mbaeyi-Nwaoha, Augustina Chinechendu Uzoigwe, Helen Onyeaka

“…The research assessed various aspects of the herbal yoghurt, including proximate composition, micronutrients, physicochemical properties, antioxidant content, sensory attributes and microbiological characteristics. …”
Get full text

Process optimization and evaluation of quality properties of natto with co-culture of Bacillus subtilis natto and Limosilactobacillus fermentum by Yi-Ni Ma, Xun Xu, Lai-Feng Chen, Jin-Ping Zhou, Zhen-Hui Cao, Qiu-Ye Lin

“…The above results indicate that co-culture of B. subtilis natto and L. fermentum can enhance the antioxidant and nattokinase activity and modify the volatile profile in natto and have the potential for application as the mixed starter in natto production.…”
Get full text

Exploring the impact of elevated pH and short maceration on the deterioration of red wines: physical and chemical perspectives by Carlos Artur Nascimento Alves, Aline Camarão Telles Camarão Telles Biasoto, Grace da Silva Nunes, Hélio Oliveira do Nascimento, Ronaldo Ferreira do Nascimento, Inglides Gomes Oliveira, Patrícia Coelho de Souza Leão, Lucicléia Barros de Vasconcelos

“…The short maceration period reduced phenolic compound extraction in high-pH musts, leading to decreased antioxidant potential and chemical stability. Critical indicators included colorimetric parameters, acetaldehyde and free SO₂ content. …”
Get full text

Evaluation of antidiabetic potential, cardio, pancreatic, nephroprotective effect, and herb-herb-drug interaction of Madhukiran formulations in T2 diabetic rats by Vrushabh S. Kondalkar, Pranali P. Polshettiwar, Ganesh B. Choudhari, Anil T. Pawar, Vishnu P. Choudhari

“…Hypoglycemic, antihyperlipidemic, antioxidant, cardio, pancreatic, reno, and hepatoprotective activities of MP, ML, MP+ML alone and combined with Metformin were evaluated. …”
Get full text

Protective mechanisms of exogenous melatonin on chlorophyll metabolism and photosynthesis in tomato seedlings under heat stress by Wangwang An, Guangzheng Wang, Jianhua Dou, Yonghai Zhang, Qing Yang, Yongmei He, Zhongqi Tang, Jihua Yu, Jihua Yu

“…MT application increased osmolytes (proline and soluble sugar), enhanced antioxidant enzyme activities [catalase (CAT), peroxidase (POD), ascorbate peroxidase (APX)], and reduced oxidative damage markers (H2O2, O2−, malondialdehyde, and conductivity). …”
Get full text

Winery By-Products In Vitro and In Vivo Effects on Atherothrombotic Markers: Focus on Platelet-Activating Factor by Maria Choleva, Smaragdi Antonopoulou, Elizabeth Fragopoulou

“…Evidence from long-term studies shows that consumption may lower total and low density lipoprotein (LDL) cholesterol, improve insulin sensitivity, decrease lipid and protein oxidative damage, enhance antioxidant capacity, and have mild anti-inflammatory action toward reducing cytokine expression and levels. …”
Get full text

Interaction between the Haptoglobin 2 Phenotype and Diabetes Mellitus on Systolic Pulmonary Arterial Pressure and Nitric Oxide Bioavailability in Hemodialysis Patients by Inbal Dahan, Evgeny Farber, Nadia Thauho, Nakhoul Nakhoul, Adi Francis, Mohamad Awawde, Andrew P. Levy, Daniel B. Kim-Shapiro, Swati Basu, Farid Nakhoul

“…A polymorphism in the antioxidant Haptoglobin (Hp) gene has been shown to regulate the bioavailability of nitric oxide (NO), a major mediator of pulmonary vascular tone. …”
Get full text

Neuroprotective Role of Transchalcone in Parkinson‘s Disease through AMP-activated Protein Kinase-mediated Signaling Pathway by Yao Cheng, Shaik Althaf Hussain, Turki Mayudh Alrubie, Xiaomin Zhang

“…Trans-chalcone, a natural flavonoid, has shown promise in various disease models because of its antioxidant and anti-inflammatory features. This study investigates the neuroprotective effects of transchalcone in a rat model of PD, focusing on its impact on the activation levels of AMP-activated protein kinase (AMPK) signaling pathway, sirtuin1 (SIRT1) and peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1α) proteins, and mitochondrial-inflammatory responses. …”
Get full text