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Comprehensive safety and toxicity analysis of 2,2’-Bipyridine derivatives in combating MRSA biofilm formation and persistence
Published 2025-01-01“…IntroductionMethicillin-resistant Staphylococcus aureus (MRSA) infections have become arduous to treat due to their capacity to form biofilms, develop persistence, and exhibit significant antimicrobial resistance. These factors contribute to the complexity of managing MRSA infections and highlight the urgent need for innovative treatment strategies.ObjectivesThis endeavor aims to evaluate the safety of 2,2’-Bipyridine (2,2’-Bipy) derivatives and their antimicrobial, anti-biofilm, and anti-persister activities in treating MRSA Infections.MethodsSix derivatives were screened for their ADMET properties and tested for minimum inhibitory concentrations against various bacterial strains using agar well diffusion and broth dilution. …”
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1683
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1684
The ‘One Health’ Paradigm: Time for Infectious Diseases Clinicians to Take Note?
Published 2010-01-01Get full text
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1685
Behavioral fever enhances T-cell responses in fish providing insights into the evolutionary integration of fever and adaptive immunity
Published 2025-06-01“…Recently, Yang et al. published a study in Proceedings of the National Academy of Sciences showing how in tilapia, behavioral fever helps optimizing antimicrobial immunity by alleviating T-cell apoptosis. …”
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1686
The Use of Guidelines for the Empiric Treatment of Hospital-Acquired Pneumonia
Published 2001-01-01“…BACKGROUND: Several practice guidelines for the empirical antimicrobial treatment of hospital-acquired pneumonia (HAP) have been developed, but the acceptance and use of such guidelines are unknown.…”
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1687
The Sounds of Silence: Public Goods, Externalities, and the Value of Infectious Disease Control Programs
Published 2009-01-01Get full text
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1688
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1689
Influence of herbal medicine in periodontics
Published 2023-07-01“…The nonsurgical treatment for periodontitis includes scaling and root planning and the use of antimicrobial agents. Patients with periodontitis are now being treated with supplementary antimicrobials as a result of a growing understanding of the infectious nature of periodontal diseases. …”
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Clinical Remission of Chronic Refractory Pelvic Symptoms in Three Men
Published 2004-01-01“…In the Manila Genitourinary Clinic, the patients were treated with microbial diagnosis, antimicrobial therapy, and 19, 27, and 21 prostatic massages respectively. …”
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1691
Efficacy of carbonyl cyanide-3-chlorophenylhydrazone in combination with antibiotics against Mycobacterium abscessus
Published 2025-02-01“…This study aimed to determine its synergistic antimicrobial effects when combined with commonly used antibiotics. …”
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1692
Adaptation for Staphylococcus aureus to hosts via insertion mutation in the accessory gene regulator agrC gene: decreased virulence and enhanced persistence capacity
Published 2025-01-01“…This mutated strain warrants clinical attention because it may lead to treatment failures and persist in patients.IMPORTANCEIn clinical antimicrobial therapy, bacterial strains often develop resistance to antimicrobial agents. …”
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1693
Antibacterial activity of selenium nanoparticles/copper oxide (SeNPs/CuO) nanocomposite against some multi-drug resistant clinical pathogens
Published 2025-01-01“…Results The Se-NPs/Cu2O nanocomposite showed a potent antimicrobial activity with MIC values ranged from 6.25 to 12.5 µg/ml for Gram-positive isolates, and 25 to 50 µg/ml for gram-negative isolates. …”
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1694
Role of the two-component system AmgRS in early resistance of Pseudomonas aeruginosa to cinnamaldehyde
Published 2025-01-01“…ABSTRACT Exposure of Pseudomonas aeruginosa to cinnamaldehyde (CNA), a natural electrophilic antimicrobial often used as self-medication to treat mild infections, triggers overproduction of the MexAB-OprM efflux system, leading to multidrug resistance. …”
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1695
Mycobacterium neoaurum Bloodstream Infection Associated with a Totally Implanted Subclavian Port in an Adult with Diabetes and History of Colon Cancer
Published 2020-01-01“…Fortunately, device removal and appropriate antimicrobial therapy guided by susceptibility data is often enough to manage these atypical mycobacterial infections.…”
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1696
Antibiogram Profile of Patients Having Urinary Tract Infection Treated with Most Commonly Used Antibiotics
Published 2025-01-01“…This study aimed to identify the bacterial pathogens causing UTIs and assess their antimicrobial sensitivity and resistance to commonly used antibiotics. …”
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Antibiotic Use among Patients Visiting Primary Hospitals in Northwest Ethiopia: A Multicenter Cross-Sectional Survey
Published 2022-01-01“…Background. Antimicrobial medications are becoming ineffective because of the surge in antimicrobial resistance. …”
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Colada morada, a traditional Ecuadorian Day of the dead beverage: Bibliometric analysis and review of the biological activity of native Ecuadorian ingredients
Published 2025-03-01“…Additionally, the antimicrobial and insect-repellent properties of A. citrodora and M. quixos, as well as the antioxidant potential of A. hybridus, underscore their functional relevance. …”
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Prevalence, Antibiotic Susceptibility Pattern and Associated Factors of Streptococcus pyogenes among Pediatric Patients with Acute Pharyngitis in Sidama, Southern Ethiopia
Published 2024-01-01“…A throat swab was cultured to isolate S. pyogenes, and antimicrobial susceptibility testing was done using standard bacteriological techniques. …”
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