New Role of Quinolones in Respiratory Tract Infections by Ronald F Grossman

“…Quinolones (both older and newer agents) have demonstrated equivalent efficacy to standard antimicrobials in the treatment of acute sinusitis. Several groups have suggested that quinolones are excellent agents in the treatment of high risk patients with acute exacerbations of chronic bronchitis. …”
Get full text

SDZ MRL 953, A Novel Synthetic Lipid a Analogue, Induces Tolerance to the Lethal Effects of Endotoxin and Enhances Nonspecific Immunity by Charles Lam, Eberhard Schütze, Emmanuel Quakyi, Ekke Liehl, Peter Stütz

“…Despite the availability of potent antimicrobials, shock due to Gram-negative rod sepsis remains an important clinical concern in immunosuppressed patients. …”
Get full text

Advances in the biosynthesis of naturally occurring benzylisoquinoline alkaloids by Wanli Zhao, Jihua Liu, Yu Chen

“…Examples include analgesics such as morphine, tetrahydropalmatine, antimicrobials such as berberine, and antineoplastic agents including cepharanthine. …”
Get full text

Investigating Gram-negative bacilli isolates’ sensitivity to ceftazidime/avibactam by Sunali, Mithilesh Kumar Jha, Mukesh Kumar, Maneesh Kumar, Nishant Ranjan

“…MDR and carbapenem resistant infections, which are common in intensive care units and hospitals, lead to increased morbidity, mortality, prolonged hospital stays, and higher healthcare costs. New antimicrobials such as ceftazidime avibactam offer potential alternatives to conventional treatments such as tigecycline and colistin, which have significant side effects and limitations. …”
Get full text

Prevalence and Characterization of Antibiotic-Resistant Staphylococcus aureus Recovered from Pasteurized Cheese Commercialized in Panama City Markets by Fermín Mejía, Nohelia Castro-del Campo, Arleny García, Katerine Rodríguez, Humberto Cornejo, Sara Ahumada-Ruiz, Marcela Soto-Beltrán, Maricela Castillo, Jordi Querol-Audi, Cristobal Chaidez-Quiroz, Alex O. Martínez-Torres

“…Among 250 disease-causing bacteria, Staphylococcus aureus is one of the major causes of food poisoning, and its resistance to multiple antimicrobials remains of crucial concern. Cheese is often contaminated when proper sanitary procedures are not followed during its production and marketing. …”
Get full text

In vitro evaluation of the antibacterial effects of monomer components of Pithecellobium clypearia against aquatic pathogens and synergy with enrofloxacin by Wenhao Wu, Jiahao Zhang, Xiaoyin He, Wei Li, Chun Liu, Biao Jiang, Youlu Su

“…Additionally, the combination of pyrogallol, luteolin, and tannic synergy with enrofloxacin (ENR) enhanced the potency of existing antimicrobials and potentially reducing dosage needs. …”
Get full text

Anti-microbial Edible Films and Their Applications to Improve Food Quality and Reduce Environmental Pollution: A Review by Yasmeen I. Al-Hadidy, Chalang M. Werdi, Anwer Ahmad Khalaf

“…The manufacture of these membranes provides many desirable properties in food, such as maintaining the moisture of the food, preventing the loss of volatile aromatic flavor compounds, reducing the migration of fats, and prolonging the storage life of the food by inhibiting microbial growth and incorporating substances into the membrane solution such as antimicrobials or antioxidants, and food additives, thus improving the appearance, sensory and nutritional properties of the food product.…”
Get full text

Elevated concentrations of quaternary ammonium compounds in childcare centers: A pilot study by Yao Cheng, Zhong Lv, Erika Schreder, Min Hu, Abby Mutic, Guomao Zheng, Amina Salamova

“…Quaternary ammonium compounds (QACs) are used as antimicrobials, preservatives, and antistatic agents in cleaning, disinfecting and personal care products, and textiles. …”
Get full text

Inhibition of <i>Salmonella enterica</i> and Enterohemorrhagic <i>Escherichia coli</i> by Ethanolic Extracts of Pomegranate Peels by Weifan Wu, Kevin Mis Solval, Jinru Chen

“…This highlights the potential of pomegranate peels as a promising natural alternative to conventional antimicrobials for controlling foodborne pathogens like <i>S. enterica</i> and <i>E. coli</i>.…”
Get full text

Is an oritavancin catheter lock solution active against biofilms of staphylococci and enterococci? by Marta Díaz-Navarro, Emilia Cercenado, Ariadna Monte, Andrés Visedo, Carmen Rodríguez, Ma Jesús Pérez-Granda, Patricia Muñoz, María Guembe

“…It is needed to further test ORT against more clinical strains and to compare its activity with other antimicrobials in a biofilm model.…”
Get full text

Optimized Synthesis of Magnesium Oxide Nanoparticles as Bactericidal Agents by Mohammad Moslem Imani, Mohsen Safaei

“…Increased antibiotic resistance of microorganisms as well as the need to reduce health-care costs necessitates the production of new antimicrobials at lower costs. For this reason, this study was aimed to optimize the synthesis of magnesium oxide nanoparticles with the greatest antibacterial activity. …”
Get full text

Description of Methodology for Testing the Synergistic and Additive Effects of Antibiotics in Vitro by Kmiecikowski Paweł Z., Gabriel Aniela, Depka Dagmara, Bogiel Tomasz

“…This paper reviews the latest literature on methods for determining the antimicrobials interactions. Clinical studies indicate significant benefits of using the phenomenon of antibiotic addition or synergy in clinical practice, not only improving the effectiveness of therapy, but also minimizing side effects and reducing the risk of developing de novo antibiotic resistance. …”
Get full text

Clinico-epidemiological characteristics of patients reported with intra-hospital infection in the Pediatric Intensive Care Unit. Cienfuegos, 2015-2019 by Lourdes Elena Duany Badell, Sadis Suárez del Villar Seuret, Tania Cantero Martínez, Maribel Caridad Águila Toledo, Sarah Hernández Malpica, Vivian Hernández Monsón

“…The use of venous catheterization occurred in 94.8% of the cases and antimicrobials due to previous infections were applied in 49.4%. …”
Get full text

Antifungal Activity of Chitosan Nanoparticles and Correlation with Their Physical Properties by Ling Yien Ing, Noraziah Mohamad Zin, Atif Sarwar, Haliza Katas

“…The need of natural antimicrobials is paramount to avoid harmful synthetic chemicals. …”
Get full text

Fungi in the Gut Microbiota: Interactions, Homeostasis, and Host Physiology by Hao-Yu Liu, Shicheng Li, Kennedy Jerry Ogamune, Abdelkareem A. Ahmed, In Ho Kim, Yunzeng Zhang, Demin Cai

“…Meanwhile, the composition of the mycobiota is influenced by multiple factors, with diet, nutrition, drug use (e.g., antimicrobials), and physical condition standing as primary drivers. …”
Get full text

PREVALENSI DAN POLA SENSITIVITAS Klebsiella pneumoniae DAN Escherichia coli  PENGHASIL EXTENDED SPECTRUM BETALAKTAMASE DI RSPAD GATOT SOEBROTO TAHUN 2021 by Hany Yusmaini, Meiskha Bahar, Erna Harfiani, Ufi Dewintera

“…Infection control, rational use of antimicrobials and prevention of transmission must continue to be pursued to reduce its prevalence. …”
Get full text

Synergistic and off-target effects of bacteriocins in a simplified human intestinal microbiome: implications for Clostridioides difficile infection control by Natalia S. Ríos Colombo, R. Paul Ross, Colin Hill

“…This can be rationally explained by antagonistic inter-species interactions within SIHUMI-C, providing new insights into how broad-spectrum antimicrobials might fail to control targeted species in complex gut microbial communities. …”
Get full text

Antibacterial activity improvement in a point mutant K45E of the pepper defensin J1-1 by Gilberto Andrés Muñoz-Pérez, Francisco A. Guillén-Chable, Gerardo Corzo, Ivan Arenas-Sosa, Lucila A. Sánchez-Cach, Georgina Estrada

“…Plant defensins have attracted much attention in the development of new antimicrobials. Yet the elucidation of their modes of action against bacterial pathogens is still incipient. …”
Get full text

Evaluation of fecal occult blood testing for rapid diagnosis of invasive diarrhea in young children. by David A Kwasi, Pelumi D Adewole, Olabisi C Akinlabi, Stella E Ekpo, Iruka N Okeke

“…Antimicrobials are only indicated in acute childhood diarrhea if it is invasive or persistent. …”
Get full text

Secondary infections in COVID-19: Antemortem and postmortem culture study by Vandana V. Kiro, Meenakshi Sharma, Sharad Srivastava, Parin Lalwani, Richa Aggarwal, Kapil D. Soni, Rajesh Malhotra, Sanjeev Lalwani, Purva Mathur, Anjan Trikha

“…All these isolates were highly resistant to antimicrobials. Conclusions: In our study, bacterial profiles in antemortem and postmortem samples were found to be similar, suggesting that resistant pathogens may be the cause of mortality in COVID-19 infected hospitalised patients.…”
Get full text