Review: trends in nanotherapeutics to manage Helicobacter pylori by R. Chitas, P. Parreira, M.C. Martins

“…Nanotherapeutics to protect and increase antimicrobials residence time in gastric settings and new bactericidal strategies based on localized formation of reactive oxygen species (ROS), after intrinsic (acidic pH) or extrinsic (light source or ultrasound device) stimulus have been developed for gastric infection management. …”
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Tuning gut microbiota by advanced nanotechnology by Yue Qi, Yueyi Wang, Xiaofei Wang, Hao Zheng, Yuan Lu

“…This review will focus on research progress in nanotechnology to modulate gut microbiota, including the direct use of nanomaterials as antimicrobials, nano-drug delivery systems, and stimulus-responsive nanotechnology. …”
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A Rare Cause of Hemophagocytic Lymphohistiocytosis: Fusobacterium Infection—A Case Report and Review of the Literature by Ghulam Rehman Mohyuddin, Heather J. Male

“…Given continued fevers despite appropriate antimicrobials, a bone marrow biopsy was performed revealing increased histiocytes with hemophagocytosis. …”
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Carbapenem-resistant Acinetobacter baumannii and Ventilator-associated Pneumonia; Epidemiology, Risk Factors, and Current Therapeutic Approaches by Malihe Kazemi Najafabadi, Rasool Soltani

“…It is related to high rates of morbidity and mortality globally, mainly because of its high capacity to develop resistance to antimicrobials. Nowadays, carbapenem-resistant A. baumannii (CRAB) has increased and represents a significant concern among carbapenem-resistant organisms. …”
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Synthesis, Characterization and Antibacterial Studies of Some Transition Metal Complexes of a Schiff Base Derived from 2-(Aminomethyl)- benzimidazole and Thiophene-2-carbaxaldehyde by Pragathi Jogi, K. Mounika, M. Padmaja, Lakshmi M., C. Gyanakumari

“…It has been found that all the complexes are antimicrobially active and show higher activity than ligand.…”
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Antibiotic and Disinfectant Susceptibility Patterns of Bacteria Isolated from Farmed Fish in Kirinyaga County, Kenya by Daniel W. Wanja, Paul G. Mbuthia, Robert M. Waruiru, Lilly C. Bebora, Helena A. Ngowi, Philip N. Nyaga

“…Fish bacterial pathogens cause diseases which result in a considerable economic impact on the aquaculture industry, necessitating the use of antimicrobials for their control. However, intensive and indiscriminate use of antimicrobials has led to increased occurrence of drug resistance in pathogenic bacteria, as well as normal flora. …”
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Sorption of Enrofloxacin and Ciprofloxacin in Agricultural Soils: Effect of Organic Matter by Marc Teixidó, Joana Medeiros, José L. Beltrán, Maria-Dolors Prat, Mercè Granados

“…Large amounts of fluoroquinolones (FQs), highly used antimicrobials in veterinary medicine, enter the soil directly through the application of manure contaminated with these chemicals. …”
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Leptospirosis Presenting with Features of Thrombotic Microangiopathy by Chaudhry Adeel Ebad, Nabeehah Moollan, Adeel Rafi Ahmed, Anthony Dorman, Colm Magee

“…The patient was managed with antimicrobials and supportive therapy. Acute kidney injury is common in leptospirosis and is often due to AIN. …”
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Bacterial Exopolysaccharides as Reducing and/or Stabilizing Agents during Synthesis of Metal Nanoparticles with Biomedical Applications by Carlos Enrique Escárcega-González, Javier A. Garza-Cervantes, Augusto Vázquez-Rodríguez, José Rubén Morones-Ramírez

“…Recently, synthesis and stabilization of metal nanoparticles have been of interest because their usefulness for many biomedical applications, such as antimicrobials, anticancer drugs, antioxidants, drug delivery systems, chemical sensors, contrast agents, and as catalysts. …”
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Molecular properties of the RmlT wall teichoic acid rhamnosyltransferase that modulates virulence in Listeria monocytogenes by Ricardo Monteiro, Tatiana B. Cereija, Rita Pombinho, Thijs Voskuilen, Jeroen D. C. Codée, Sandra Sousa, João H. Morais-Cabral, Didier Cabanes

“…Abstract Wall teichoic acids (WTAs) from the major Gram-positive foodborne pathogen Listeria monocytogenes are peptidoglycan-associated glycopolymers decorated by monosaccharides that, while not essential for bacterial growth, are required for bacterial virulence and resistance to antimicrobials. Here we report the structure and function of a bacterial WTAs rhamnosyltransferase, RmlT, strictly required for L. monocytogenes WTAs rhamnosylation. …”
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Optimizing the Synthesis of Novel Calcium Carbonate/Cobalt Oxide Nanocomposite With Highest Antifungal Activity by Nima Fallahnia, Mohammad Salmani Mobarakeh, Hasti Sarabikia, Mohsen Safaei

“…Today, the rise of opportunistic infections and their resistance to current antifungal drugs has led to the inevitable need to produce effective antimicrobials at a reasonable cost. This study aimed at producing a calcium carbonate/cobalt oxide nanocomposite with the most excellent antifungal activity against Candida albicans (C. albicans). …”
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Tigecycline-induced acute pancreatitis with electrocardiogram changes in renal insufficiency elderly by Hong Chin Wee, Ru Shing Ng, Loke Meng Ong

“…Background: The prevalence of multidrug-resistant and extensively drug-resistant pathogens has led to increased reliance on broad-spectrum antimicrobials, such as tigecycline. This medicine is commonly used to treat complicated skin and intraabdominal infections as well as community-acquired pneumonia. …”
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Systematic Analysis of Environmental Chemicals That Dysregulate Critical Period Plasticity-Related Gene Expression Reveals Common Pathways That Mimic Immune Response to Pathogen by Milo R. Smith, Priscilla Yevoo, Masato Sadahiro, Ben Readhead, Brian Kidd, Joel T. Dudley, Hirofumi Morishita

“…These chemicals included pesticides (e.g., pyridaben), antimicrobials (e.g., bacitracin), metals (e.g., mercury), anesthetics (e.g., halothane), and other chemicals and mixtures (e.g., vehicle emissions). …”
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Synthesis and Antibacterial Activity of Some New Phenothiazine Derivatives by Pawan Kumar Swarnkar, P. Kriplani, G. N. Gupta, K. G. Ojha

“…A series of some new phenothiazine derivatives were synthesized with the objective for evaluation as antimicrobials. The title compounds were prepared by a five step synthesis scheme. 2-Amino-6-substituted benzothiazoles (1) on diazotization afford 6-substituted benzothiazolyl-2-diazonium chlorides (2). …”
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Vacuum-Assisted Closure Combined with a Myocutaneous Flap in the Management of Osteomyelitis in a Dog by Jeremy L. Shomper, Julia V. Coutin, Otto I. Lanz

“…Two years prior to presentation, the patient sustained a left tibial fracture, which was repaired with an intramedullary (IM) pin and two cerclage wires. Multiple antimicrobials were utilized during this time. Clinical Findings. …”
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Guanosine enhances the bactericidal effect of ceftiofur sodium on Streptococcus suis by activating bacterial metabolism by Yue Dong, Xiaona Liu, Shanshan Xiong, Mingyu Cao, Haojie Wu, Long Chen, Mengmeng Zhao, Yadan Zheng, Zhiyun Zhang, Yanyan Liu, Yanhua Li, Qianwei Qu, Chunliu Dong

“…In addition, the function of the cell membrane is affected by guanosine and the accumulation of antimicrobials in the bacteria increased. Bacterial-oxidative stress and DNA damage induced by guanosine is also one of the mechanisms by which the antibacterial effect is enhanced. …”
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Risk Factors for Foot Amputation in Patients Hospitalized for Diabetic Foot Infection by Maria Teresa Verrone Quilici, Fernando de Sá Del Fiol, Alexandre Eduardo Franzin Vieira, Maria Inês Toledo

“…The results showed a 42% higher risk for progression to amputation in patients with previous use of antimicrobials. Also, the amputation risk was 26% higher for those less compliant with diabetes treatment. …”
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The utilization of microbial cell-free DNA next-generation sequencing for the detection of human herpesvirus-8 in a quaternary care center by Rebecca Berger, Jennifer Jacobe, Fernando H. Centeno, Todd Lasco, Mayar Al Mohajer

“…Management changed in six patients post-testing due to outpatient specialist referral or adjusting antimicrobials. Conclusion: mcfDNA NGS can aid clinicians in identifying HHV8-related diseases before tissue sampling and adjusting treatment plans in patients with nonspecific disease manifestations.…”
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Multiplex Tests for Respiratory Tract Infections: The Direct Utility of the FilmArray Respiratory Panel in Emergency Department by Siyuan Yang, Hui Li, Yunxia Tang, Fengting Yu, Chengjie Ma, Huimin Zhang, Lin Pang, Hongxin Zhao, Linghang Wang

“…The information provided by the FilmArray had an impact on the prescription of antimicrobials, and there were differences in the rates of antibiotic prescriptions and anti-influenza prescriptions among patients. …”
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The appropriate nutrient conditions for methicillin-resistant Staphylococcus aureus and Candida albicans dual-species biofilm formation in vitro by Pavlína Vávrová, Ondřej Janďourek, Adéla Diepoltová, Petr Nachtigal, Klára Konečná

“…The study demonstrates that the Lubbock medium provided the most appropriate amount of nutrients regarding the biomass structure and the highest degree of tolerance to selected antimicrobials with the evident contribution of the biofilm matrix. …”
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