Comprehensive genomic surveillance reveals transmission profiles of extensively drug-resistant tuberculosis cases in Pará, Brazil by Davi Josué Marcon, Davi Josué Marcon, Abhinav Sharma, Alex Brito Souza, Alex Brito Souza, Rafaella Bonfim Barros, Valnete das Graças Dantas Andrade, Ricardo José de Paula Souza Guimarães, Luana Nepomuceno Gondim Lima, Luana Nepomuceno Gondim Lima, Lúcia Helena Martins Tavares Monteiro, Ana Judith Pires Garcia Quaresma, Ana Judith Pires Garcia Quaresma, Layana Rufino Ribeiro, Layana Rufino Ribeiro, Philip Noel Suffys, Robin Mark Warren, Carlos Augusto Abreu Alberio, Karla Valéria Batista Lima, Karla Valéria Batista Lima, Emilyn Costa Conceição

“…Bedaquiline, an antimicrobial used to treat drug-resistant tuberculosis (DR-TB), was introduced in Brazil in October 2021. …”
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Gaps in U.S. livestock data are a barrier to effective environmental and disease management by Rebecca Logsdon Muenich, Sanskriti Aryal, Amanda J Ashworth, Michelle L Bell, Melanie R Boudreau, Stephanie A Cunningham, K Colton Flynn, Kerry A Hamilton, Ting Liu, Michael L Mashtare, Natalie G Nelson, Barira Rashid, Arghajeet Saha, Danica Schaffer-Smith, Callie Showalter, Aureliane Tchamdja, Jada Thompson

“…Issues such as soil, water, and air pollution, greenhouse gas emissions, aquifer depletion, antimicrobial resistance genes, and zoonotic disease outbreaks have all been linked to livestock operations. …”
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Rapid molecular assays versus blood culture for bloodstream infections: a systematic review and meta-analysisResearch in context by Gabriella Anna Rapszky, Uyen Nguyen Do To, Veronika Eszter Kiss, Tamás Kói, Anna Walter, Dorottya Gergő, Fanni Adél Meznerics, Márton Rakovics, Szilárd Váncsa, Lajos Vince Kemény, Dezső Csupor, Péter Hegyi, Michael R. Filbin, Csaba Varga, Bánk G. Fenyves

“…Summary: Background: Timely management of sepsis with early targeted antimicrobial therapy improves patient outcomes. Rapid molecular assays (RMAs) have emerged, enabling the detection of bloodstream infection (BSI) with a shorter turnaround time than blood cultures (BCs). …”
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Prevalence and determinants of faecal carriage of carbapenem- and third-generation cephalosporin-resistant Enterobacterales: a cross-sectional household survey in northern VietnamR... by Max van Wijk, Hoang Huy Tran, Bich Ngoc Thi Vu, Costanza Tacoli, Tu Cam Thi Nguyen, Quynh Dieu Pham, Thương Hong Thi Nguyen, Trang Thu Nguyen, Hien Anh Thi Nguyen, Tung Son Trinh, Thai Duy Pham, Huong Kieu Thi Tran, Dung Tien Viet Vu, Duc Anh Dang, Tien Dac Tran, Duong Thanh Nguyen, H. Rogier van Doorn, Thomas Kesteman, Sonia Lewycka

“…Summary: Background: Antimicrobial resistance (AMR) is a silent pandemic causing 1.27 million deaths in 2019, disproportionately affecting low- and middle-income countries, but resistance among commensal microbiota and the determinants of carriage have not been widely reported. …”
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Bacterial Multiresistance and Microbial Diversity of Milk Received by a University Hospital Milk Bank by Dayane da Silva Zanini, Benedito Donizete Menozzi, Wanderson Sirley Reis Teixeira, Felipe Fornazari, Gismelli Cristiane Angeluci, Raquel Cuba Gaspar, Lucas Franco Miranda Ribeiro, Carlos Eduardo Fidelis, Marcos Veiga dos Santos, Juliano Gonçalves Pereira, Helio Langoni

“…Even though there is a restriction on medications prescribed for pregnant and breastfeeding women, some antimicrobials are accepted, as long as they are used correctly and as they can increase the selection pressure for resistant bacteria. …”
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Microbiological tests of fresh bull semen collected at breeding establishment by M. A. Sushkova, I. Ya. Stroganova, S. А. Schislenko

“…Isolated microorganism cultures were tested for their susceptibility to antibiotics with disc-diffusion method according to the Methodical Guidelines 4.2.1890-04 «Testing of microorganisms for their susceptibility to antimicrobials» using discs containing eight antimicrobials. …”
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Levofloxacin-Induced Acute Hyperpigmentation Changes in a Chronic Kidney Disease Patient by Shakuntala S. Patil, Sachin M. Patil, Ryan Campbell, Manisha Singh, Matthew Plotkin

“…Sunlight exposure can worsen the pigmentation seen with some of the above antimicrobials (e.g., dapsone). Here, we describe an older adult white woman presenting with acute cutaneous; hyperpigmentation of the bilateral lower extremities while on levofloxacin therapy. …”
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Polymyxin Combination Therapy and the Use of Serum Bactericidal Titers in the Management of KPC-Producing Klebsiella pneumoniae Infections: A Report of 3 Cases by Eric Gomez, Martha Sanchez, Zonaira Gul, Carl Urban, Noriel Mariano, Robert H. K. Eng, David B. Huang, Tom Chiang

“…We report three cases of KPC-producing Klebsiella pneumoniae bacteremia that were successfully treated using combination therapy with polymyxin B and other antimicrobials. Serum bactericidal titers were determined and provided additional clinical guidance in the management of such patients.…”
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Infection prevention in the immunocompromised traveler due to conditions other than transplantation: a review by Joseph Sassine, Emily A. Siegrist, Rita Wilson Dib, José Henao-Cordero, Nelson Iván Agudelo Higuita

“…This narrative review explores the risks related to infection in immunocompromised travelers due to conditions other than transplantation, and evaluates the evidence behind current prophylactic strategies, including immunizations, antimicrobials, and non-pharmacological interventions, to prevent various infection and how the current evidence applies to this special patient population, from the perspective of a US-based traveler.…”
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Microbiota Associated with Infections of the Jaws by Elerson Gaetti-Jardim, Luis Fernando Landucci, Kathlenn Liezbeth de Oliveira, Iracy Costa, Robson Varlei Ranieri, Ana Cláudia Okamoto, Christiane Marie Schweitzer

“…In such cases, local treatment associated with systemic antimicrobials should be used in order to eradicate the sources of contamination. …”
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Urinary Tract Infections in Adults by Evan B. Cohn, Anthony J. Schaeffer

“…While there have also been advances in the realm of antimicrobials, there have been numerous problems with multiple drug resistant organisms. …”
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Did the resurgence of childhood lower respiratory infections offset the initial benefit of COVID-19-related non-pharmaceutical interventions in children? A time-series analysis by Inès Fafi, Zein Assad, Léa Lenglart, Zaba Valtuille, Florentia Kaguelidou, Camille Aupiais, Aurélie Bourmaud, Alexis Rybak, Stéphane Bechet, Corinne Levy, Robert Cohen, Bruno Frandji, Andreas Werner, François Angoulvant, Romain Basmaci, Naïm Ouldali

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High-risk Pseudomonas aeruginosa clones harboring β-lactamases: 2024 update by Verónica Roxana Flores-Vega, Santiago Partida-Sanchez, Miguel A. Ares, Vianney Ortiz-Navarrete, Roberto Rosales-Reyes

“…Carbapenem-resistant Pseudomonas aeruginosa is defined by the World Health Organization as a “high priority” in developing new antimicrobials. Indeed, the emergence and spread of multidrug-resistant (MDR) or extensively drug-resistant (XDR) bacteria increase the morbidity and mortality risk of infected patients. …”
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Septic Pulmonary Emboli and Renal Abscess Caused by Staphylococcus aureus in an HIV-Infected Patient by Isaí Medina-Piñón, Alan Ledif Reyes-Mondragón, Michel Fernando Martínez-Reséndez, Adrián Camacho-Ortiz

“…Methicillin-resistant Staphylococcus aureus (MRSA) was identified as the cause of sepsis and successfully treated with surgery and antimicrobials. Intravenous vancomycin was the primary therapy, followed by oral linezolid after resolution of bacteremia.…”
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Growth, Reduction, and Survival of Bacteria on Tomatoes by Angela M. Valadez, Keith R. Schneider, Michelle D. Danyluk

“…The authors evaluated bacterial studies on natural antimicrobials and detergents, as well as food processing, cross-contamination, and shelf-life studies. …”
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Growth, Reduction, and Survival of Bacteria on Tomatoes by Angela M. Valadez, Keith R. Schneider, Michelle D. Danyluk

“…The authors evaluated bacterial studies on natural antimicrobials and detergents, as well as food processing, cross-contamination, and shelf-life studies. …”
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Complex management of GS (Good's syndrome) with persistent COVID-19 infection and polymicrobial infections: A case report by Yijiao Xu, Lumin Wang, Zhisheng Chen, Ying Huang, Jiaxin Liu, Huijun Zhang, Hongni Jiang

“…The report further emphasizes a multifaceted treatment approach, incorporating antivirals, antifungals, antimicrobials, immunoglobulins, and antifibrotic therapy, which ultimately led to an improvement in the patient's condition. …”
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Successful Use of Octreotide Therapy for Refractory Levofloxacin-Induced Hypoglycemia: A Case Report and Literature Review by Matthew R. Watson, Ceressa T. Ward, Amit Prabhakar, Babar Fiza, Vanessa Moll

“…Fluoroquinolones are commonly prescribed antimicrobials that have been implicated in alterations of glucose metabolism. …”
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Macrolides in Chronic Inflammatory Skin Disorders by Abdullateef A. Alzolibani, Khaled Zedan

“…Since that time, macrolides have been found to have a large number of anti-inflammatory properties in addition to being antimicrobials. These observations provided the rationale for many studies performed to assess the usefulness of macrolides in other inflammatory diseases including skin and hair disorders, such as rosacea, psoriasis, pityriasis rosea, alopecia areata, bullous pemphigoid, and pityriasis lichenoides. …”
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Bioactive Fused Pyrazoles Inspired by the Adaptability of 5-Aminopyrazole Derivatives: Recent Review by Dana M. Odeh, Mohanad M. Odeh, Taghrid S. Hafez, Ashraf S. Hassan

“…Many compounds inspired by the 5-aminopyrazole derivatives possess a wide spectrum of biological activities and medicinal applications such as antioxidants, anticancer agents, enzyme inhibitors, antimicrobials, and anti-tuberculosis activities. This review summarizes the recently reported synthesis methods and biological activities of fused pyrazole and pyrazole-based derivatives based on 5-aminopyrazole compounds within the last 5 years (2020 to present). …”
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