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Effects of organic acid blends on the growth performance, intestinal morphology, microbiota, and serum lipid parameters of broiler chickens
Published 2025-01-01“…In conclusion, Acidapure, as a blend of organic acids, effectively enhances the growth performance and gut health of broilers, making it a viable and safe alternative to traditional antimicrobial growth promoters.…”
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2862
Trends and advances in Leptospira, a bibliometric analysis
Published 2025-01-01“…Prominent research areas included restriction endonucleases, monoclonal antibodies, outer membrane proteins, water environments, detection methods, and antimicrobial agents. Research focus has shifted from early genomic and antigenic studies to investigations into outer membrane protein functions and environmental persistence, culminating in recent advances in molecular mechanisms and diagnostic technology development.ConclusionThis bibliometric analysis provides a comprehensive snapshot of leptospirosis research, emphasizing collaborations and impact among authors, countries, institutions, and journals. …”
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2864
Injectable Nanocomposite Hydrogel for Accelerating Diabetic Wound Healing Through Inflammatory Microenvironment Regulation
Published 2025-02-01“…The assessment encompassed the temperature-sensitive properties, pH-responsive release, antimicrobial activity, and ROS scavenging capabilities of the MCC@ZIF-8@Cur hydrogel. …”
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2865
Identification of <i>Bacillus anthracis</i> Strains from Animal Cases in Ethiopia and Genetic Characterization by Whole-Genome Sequencing
Published 2025-01-01“…The genomes of the strains were also analyzed to detect the presence of antimicrobial resistance and virulence genes. The whole genome SNP analysis showed that the Ethiopian <i>B. anthracis</i> strains were grouped in the A clade. …”
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2866
Molecular epidemiology of extended-spectrum beta-lactamases and carbapenemases-producing Shigella in Africa: a systematic review and meta-analysis
Published 2025-01-01“…The findings from the study suggest that ESBL and CR-producing Shigella pose a significant public health threat in Africa. Effective antimicrobial resistance (AMR) surveillance strategies are needed to improve the management and treatment of Shigella infections in Africa.…”
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2867
Genomic characteristics of ST6115 carbapenem-resistant Klebsiella pneumoniae coharboring blaNDM-1 and blaIMP-4
Published 2025-02-01“…Subsequently, a phylogenetic analysis was employed to ascertain the clonal relationship of these strains. The antimicrobial susceptibility testing (AST) was evaluated through the application of the minimum inhibitory concentration (MIC) methodology by the broth microdilution method. …”
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2868
Antistaphylococcal Triazole-Based Molecular Hybrids: Design, Synthesis and Activity
Published 2025-01-01“…The obtained [2-(3-R-1<i>H</i>-[1,2,4]-triazol-5-yl)phenyl]amines reveal significant antimicrobial activity and deserve further structural modification and detailed study as effective antistaphylococcal agents. …”
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2869
Identification of Staphylococcus aureus, Enterococcus faecium, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii from Raman spectra by Artificial Intelligen...
Published 2025-02-01“…This finding confirms the clinical utility of the system while laying a solid foundation for the future development of antimicrobial resistance prediction models.…”
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2870
Genotyping of extended-spectrum beta-lactamase-producing Escherichia coli isolated from wastewater of dairy farms in East Java, Indonesia
Published 2025-01-01“…Addressing this issue necessitates stringent antimicrobial use policies, improved wastewater management, and enhanced biosecurity measures. …”
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2871
Population genetic analysis of clinical Mycobacterium abscessus complex strains in China
Published 2025-01-01“…BackgroundTo explore the genetic characteristics of the Mycobacterium abscessus complex (MABC) population in China, given its rising clinical importance among nontuberculous mycobacteria.MethodsWe conducted population genetic analyses on 360 MABC genomes from China, focusing on core genome multilocus sequence typing (cgMLST), pan-genome characterization, population genetics, and antimicrobial resistance gene profiling.ResultsOur analysis identified 273 M. abscessus subsp. abscessus (MabA) and 87 M. abscessus subsp. massiliense (MabM) isolates, uncovering 68 sequence types (STs), with ST5 being the most common. cgMLST classified 33.3% of isolates into six dominant circulating clones (DCCs) and 49.4% into 59 genomic clusters at a threshold of 25 different alleles, including 18 international clusters linking Chinese isolates with seven other countries. …”
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2872
Exploring the multifaceted roles of Sonneratia apetala and Nipa fruticans in coastal habitat restoration and bioactive properties discovery
Published 2025-02-01“…Results: S. apetala fruits exhibit substantial antioxidant, antimicrobial, analgesic, antidiarrheal, and anti-diabetic properties. …”
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2873
Effectiveness of case-area targeted interventions including vaccination on the control of epidemic cholera: protocol for a prospective observational study
Published 2022-07-01“…Cohort studies will measure effects on reducing incidence among household contacts and changes in antimicrobial resistance.Ethics and dissemination The ethics review boards of MSF and the London School of Hygiene and Tropical Medicine have approved a generic protocol. …”
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2874
The immunoglobulin of yolk and cerium oxide-based fibrous poly(L-lactide-co-glycolide)/gelatin dressings enable skin regeneration in an infectious wound model
Published 2025-02-01“…The immunoglobulin of yolk (IgY) exhibits immunotherapeutic potential for the potential treatment of antimicrobial-resistant pathogens, while cerium oxide nanoparticles (CeO2 NPs) could scavenge superoxide dismutase (SOD) and inflammation. …”
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Emergence of mcr-8.1-bearing MDR-hypervirulent Klebsiella pneumoniae ST307
Published 2025-02-01“…We further identified antimicrobial resistance (AMR) genes in four Armenian isolates, including blaOXA-1, blaTEM-1D, blaSHV-28, dfrA14, tet(A), sul2, qnrB1, aac(6´)-Ib-cr, strA, strB and the extended-spectrum β-lactamase gene blaCTX-M-15. …”
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2877
Vascular Access Device Infections: Current Management Practices and the Role of Multidisciplinary Teams at a Large Hospital in Northern Italy
Published 2025-01-01“…These options included variations in VAD removal, timing of repositioning, and combinations of antimicrobial lock therapy and systemic therapy. Concordance between real-life practices and VAT recommendations was evaluated using Cohen’s kappa coefficient. …”
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2878
Single-cell profiling reveals a reduced epithelial defense system, decreased immune responses and the immune regulatory roles of different fibroblast subpopulations in chronic atro...
Published 2025-02-01“…Our analysis revealed that chief cells and parietal cells exhibited a loss of detoxification ability and that surface mucous cells displayed a reduced antimicrobial defense ability in CAG lesions. The mucous neck cells in CAG lesions showed upregulation of genes related to cell cycle transition, which may lead to aberrant DNA replication. …”
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2879
Technological dental sealants: in vitro evaluation of material properties and antibiofilm potential
Published 2025-02-01“…Conclusions Bioactive materials and self-adhesive/self-etching for sealing pits and fissures did not demonstrate superior mechanical and antimicrobial properties performance compared to conventional techniques.…”
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Genome analysis of colistin-resistant Salmonella isolates from human sources in Guizhou of southwestern China, 2019–2023
Published 2025-01-01“…Therefore, it is necessary to monitor CL-R Salmonella in Guizhou and systematically elucidate their characteristics-related resistance, virulence, and molecular epidemiology to develop effective public health strategies against resistant pathogens.MethodsThe CL-R Salmonella isolates were identified from 933 Salmonella isolates by antimicrobial resistance testing. To further evaluate the molecular epidemiology, the CL-R Salmonella isolates underwent whole-genome sequencing (WGS) analysis followed by bioinformatic analysis.ResultsA total of 43 CL-R isolates (4.6%) were identified from 933 Salmonella isolates, of which 39 isolates being MDR (resistance to three or more classes of antimicrobials). …”
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