Clinical Characteristics, Pathogen Distribution, and Factors Affecting Visual Outcomes of Pediatric Post-Traumatic Endophthalmitis by Xiaoxia Li, Yibin Zhou, Zhi Chen, Xiuwen Zhang, Zimei Zhou, Maureen Boost, Taomin Huang, Xingtao Zhou

“…These findings highlight the need for timely surgical and antimicrobial interventions tailored to each patient to improve visual prognosis.…”
Get full text

First Detection and Genomic Characterization of Linezolid-Resistant <i>Enterococcus faecalis</i> Clinical Isolates in Bulgaria by Tanya V. Strateva, Preslava Hristova, Temenuga J. Stoeva, Hristina Hitkova, Slavil Peykov

“…The strains designated Efs2503-bg (inpatient from Pleven) and Efs966-bg (outpatient from Varna) were recovered from wounds in 2018 and 2023, respectively. Antimicrobial susceptibility testing, whole-genome sequencing, multilocus sequence typing, and phylogenomic analysis based on 332 linezolid-resistant <i>E. faecalis</i> genomes were performed. …”
Get full text

The Toxoplasma rhoptry protein ROP55 is a major virulence factor that prevents lytic host cell death by Margarida T. Grilo Ruivo, Ji-hun Shin, Todd Lenz, Stephanie Y. Matsuno, Katherine Olivia Yanes, Arnault Graindorge, Maguy Hamie, Laurence Berry-Sterkers, Mathieu Gissot, Hiba El Hajj, Karine G. Le Roch, Melissa B. Lodoen, Maryse Lebrun, Diana Marcela Penarete-Vargas

“…Abstract Programmed-cell death is an antimicrobial defense mechanism that promotes clearance of intracellular pathogens. …”
Get full text

Enhanced bone regeneration using sodium alginate and polyvinyl alcohol incorporating TiO2 nanoparticles composite film for orthopedic application by Guoying Zhang, Xunkai Hou, Zhen Geng, Mahani Yusoff, Nur Adibah Roslan, Mohd Hasmizam Razali

“…Bone tissue regeneration remains a significant challenge in orthopedic medicine due to the limited osteogenic and antimicrobial properties of conventional biomaterials. …”
Get full text

Determination of Carbapenemase-Producing OXA- 48 and KPC Genes in Antibiotic-Resistant Gram-Negative Bacilli Isolated from Infectious Samples of Cardiovascular Patients Hospitalize... by Mina Owrang, Ebrahim Taheri Hossein Abad, Shakiba Shafaie

“…All bacterial isolates were identified using standard biochemical methods. The antimicrobial susceptibility pattern of the isolates was assessed using the disc diffusion test (DDT) in accordance with Clinical and Laboratory Standards Institute (CLSI) guidelines. …”
Get full text

The Potential of Ethanol Extract of Aleurites Moluccanus Leaves as TNF-α Inhibitor in Oral Incision Wound Care Model by Elfi Zahara, . Darmawi, Ummu Balqis, Cut Soraya

“…These major compounds have significant bioactivities, including antioxidant, antibacterial, and antimicrobial properties. Molecular docking tests identified stigmasta-5,22-dien-3-ol and cycloheptadecanol as showing strong docking activity against TNF-α. …”
Get full text

Using a robust model to detect the association between anthropometric factors and T2DM: machine learning approaches by Nafiseh Hosseini, Hamid Tanzadehpanah, Amin Mansoori, Mostafa Sabzekar, Gordon A. Ferns, Habibollah Esmaily, Majid Ghayour-Mobarhan

Get full text

Correlation Analysis Between Multi-Drug Resistance Phenotype and Virulence Factor Expression of Clinical <i>Pseudomonas aeruginosa</i> by Wenli Xu, Runcheng Zhou, Jingwei Pan, Zhuangcong Liu, Xuyu Huang, Yueqiao Lin, Nan Li, Kecan Chen, Wenbo Sun, Yi Deng, Anping Yang, Xin Chen

“…<i>Pseudomonas aeruginosa</i> (PA), as a common pathogen of nosocomial infections, has been experiencing an increasing rate of drug resistance with the widespread use and abuse of antimicrobial drugs. High-drug-resistance and high-virulence phenotypes are two distinctive features of the strong pathogenicity of multi-drug-resistant PA. …”
Get full text

Screening of Indigenous Oxalate Degrading Lactic Acid Bacteria from Human Faeces and South Indian Fermented Foods: Assessment of Probiotic Potential by Sivasamy Gomathi, Ponnusamy Sasikumar, Kolandaswamy Anbazhagan, Sundaresan Sasikumar, Murugan Kavitha, M. S. Selvi, Govindan Sadasivam Selvam

“…Three strains, Lactobacillus fermentum TY5, Lactobacillus fermentum AB1, and Lactobacillus salivarius AB11, exhibited good adhesion to HT-29 cells and strong antimicrobial activity. They also conferred resistance to kanamycin, rifampicin, and ampicillin, but were sensitive to chloramphenicol and erythromycin. …”
Get full text

Detection of Delafloxacin Resistance Mechanisms in Multidrug-Resistant <i>Klebsiella pneumoniae</i> by András Kubicskó, János Juhász, Katalin Kamotsay, Dora Szabo, Béla Kocsis

“…<b>Methods:</b> In our study, 43 <i>K. pneumoniae</i> strains were assessed, antimicrobial susceptibility testing was performed via the broth microdilution method, and the minimum inhibitory concentration (MIC) values for ciprofloxacin, delafloxacin, levofloxacin, moxifloxacin, ceftazidime, cefotaxime, and imipenem were determined. …”
Get full text

Mode of action of silver-based perovskite against Gram-negative bacteria by Fereshteh Fani, Cyrus Talebpour, Philippe Leprohon, Hossein Salimnia, Houshang Alamdari, Marc Ouellette

“…In our previous work, we described AgNbO3 nanoparticles (AgNbO3 NPs) prepared using a ceramic method, followed by high-energy and low-energy ball-milling processes, which exhibited antimicrobial activity with negligible release of Ag+ in deionized water. …”
Get full text

Probiogenomic analysis of Limosilactobacillus fermentum SD7, a probiotic candidate with remarkable aggregation abilities by Thunchanok Yaikhan, Monwadee Wonglapsuwan, Nuntiya Pahumunto, Natakorn Nokchan, Rawee Teanpaisan, Komwit Surachat

“…In addition, L. fermentum SD7 genome contains four strain-specific putative CRISPR-associated genes and lacks antimicrobial resistance and virulence genes. Importantly, we identified 27 genes in L. fermentum SD7 genome that are linked to aggregation ability, which is supported by our probiogenomic analysis. …”
Get full text

Immunogenicity of Type IV Pilin Proteins from <i>Clostridium perfringens</i> in Chickens by Audrey Charlebois, Nicolas Deslauriers, Lila Maduro, Martine Boulianne

“…With increasing pressure to reduce antimicrobial use, the development of alternative preventive tools is needed. …”
Get full text

Sonication: A Valuable Technique for Diagnosis and Treatment of Periprosthetic Joint Infections by D. S. Evangelopoulos, I. P. Stathopoulos, G. P. Morassi, S. Koufos, A. Albarni, P. K. Karampinas, A. Stylianakis, S. Kohl, S. Pneumaticos, J. Vlamis

“…In addition, periprosthetic tissue specimens (>5) were collected and cultured according to standard practice. The duration of antimicrobial interruption interval before culture sampling was recorded. …”
Get full text

Dissecting the biophysical mechanisms of oleate hydratase association with membranes by William A. Lathram, Robert J. Neff, Ashley N. Zalla, James D. Brien, Vivekanandan Subramanian, Christopher D. Radka

“…OhyA catalyzes the hydration of unsaturated fatty acids, playing a key role in bacterial pathogenesis by neutralizing host antimicrobial fatty acids. OhyA binds the membrane bilayer to access membrane-embedded substrates for catalysis, and structural studies have revealed that OhyA forms oligomers on membrane surfaces, stabilized by both protein-protein and protein-lipid interactions. …”
Get full text

Novel Organotin(IV) Schiff Base Complexes with Histidine Derivatives: Synthesis, Characterization, and Biological Activity by Ariadna Garza-Ortiz, Carlos Camacho-Camacho, Teresita Sainz-Espuñes, Irma Rojas-Oviedo, Luis Raúl Gutiérrez-Lucas, Atilano Gutierrez Carrillo, Marco A. Vera Ramirez

“…The second structure is spectroscopically described as a tetrahedral tin complex with four donating atoms (one oxygen atom coordinated to the metal and three carbon atoms belonging to the alkyl or aryl substituents), with one molecule of ligand attached. The antimicrobial activity of the tin compounds has been tested against the growth of bacteria in vitro to assess their bactericidal properties. …”
Get full text

Key bacterial vaginosis-associated bacteria influence each other's growth in biofilms in rich media and media simulating vaginal tract secretions by Lúcia G.V. Sousa, Christina A. Muzny, Nuno Cerca

“…Interestingly, we found that P. bivia growth in NYCIII was influenced by the cell-free supernatant (CFS) of F. vaginae and by the CFS of G. vaginalis in mGTS. This antimicrobial activity appears to happen due to the acidification of the media. …”
Get full text

Effect of ultrasonically-activated irrigation protocols used for regenerative endodontics on removal of dual species biofilm in a three-dimensionally printed tooth model: in vitro... by Saeed Mustafa, Marwa A. Meheissen, Sybel Moussa, Rania ElBackly

“…Conclusion Results of the current study propose that a 3D-printed mature tooth model can be effectively used to analyze the antimicrobial effects of different irrigation protocols on dual-species biofilm. …”
Get full text

Effects of Adipose-tissue Derived Mesenchymal Stem Cells on PBMCs in Co-culture with HeLa Cell Line by Maryam Dorfaki, mahdi ghatrehsamani, fahimeh Lavi Arab, Mona Roozbehani, Majid Khoshmirsafa, Reza Falak, Fatemeh Keshavarz, Fatemeh Faraji

Get full text

Dynamic Monitoring of sTREM-1 and Other Biomarkers in Acute Cholangitis by Jiahui Jiang, Xiaolei Wang, Tongtong Cheng, Mingyue Han, Xinxin Wu, Haitong Wan, DaojunYu

“…PCT alone is sufficient enough to diagnose sepsis with AC. sTREM-1 is the best biomarker to monitor patients’ response to antimicrobial therapy and biliary drainage.…”
Get full text