Systematic review of innate immune responses against Mycobacterium tuberculosis complex infection in animal models by Luisa Maria Nieto Ramirez, Carolina Mehaffy, Karen Marie Dobos

“…Key innate immune factors/pathways identified included TNF-α, neutrophil recruitment, ROS/RNS responses, autophagy, inflammasomes, and antimicrobial peptides, with homologous proteins identified in insects. …”
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A Comparative Study to Evaluate the Effectiveness between Synergic Activities of 0.1% Polyhexanide and Rigenase® (Fitostimoline® Plus spray) versus a Hydrating Formulation for the... by Eugenia Veronica Di Brizzi, Anna Balato, Stefano Caccavale, Amalia Lupoli, Carlo Panetti, Giuseppe Argenziano

“…Polyhexamethylene biguanide (PHMB) and Rigenase® (a patented Triticum vulgare extract) show promise in tissue repair and antimicrobial activity. Objective: The aim of this study was to compare the effectiveness of two topical treatments, Fitostimoline® Plus spray and a hydrating formulation with hyaluronic acid, in rubbing injuries secondary to atopic dermatitis. …”
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Isolation of Helicobacter pylori from Gastric Biopsy of Dyspeptic Patients in Ghana and In Vitro Preliminary Assessment of the Effect of Dissotis rotundifolia Extract on Its Growth by Michael Buenor Adinortey, Charles Ansah, Cynthia Ayefoumi Adinortey, Ansumana Sandy Bockarie, Martin Tangnaa Morna, Damian H. Amewowor

“…This TTC dye method was further used in an antimicrobial susceptibility assay involving Dissotis rotundifolia extract (DRE). …”
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Study of Antibacterial Activity of Root Bark, Leaves, and Pericarp Extracts of Diploknema butyracea and Evaluation of Prospective Antioxidant Activity by Alisha Karki Chhetry, Subhila Dhakal, Lalita Chaudhary, Khimdhoj Karki, Ram Bahadur Khadka, Gautam Prasad Chaudhary, Tonking Bastola, Amrit Poudel, Pramod Aryal, Jitendra Pandey

“…Our study showed that methanolic root bark extract exhibited the potent antimicrobial activity against Staphylococcus aureus, Staphylococcus epidermidis, and Klebsiella pneumonia with an average zone of inhibition of 17.33 mm, 14.33 mm, and 13.0 mm, respectively. …”
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Bacterial Profile among Patients with Suspected Bloodstream Infections in Ethiopia: A Systematic Review and Meta-Analysis by Birhan Alemnew, Habtamu Biazin, Asmamaw Demis, Melese Abate Reta

“…Globally, the emergency and raised resistance rate of bacterial antimicrobial resistance is becoming a prominent problem, and it is difficult to treat patients having sepsis. …”
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Clinical Characteristics and Risk Factors for Multidrug-Resistant Enterobacter cloacae Complex Bacteremia in a Chinese Tertiary Hospital: A Decade Review (2013–2022) by Han M, Hua M, Xie H, Li J, Wang Y, Shen H, Cao X

“…Mei Han,1,2,* Miaomiao Hua,3,* Hui Xie,1 Jia Li,1 Yijun Wang,2,4 Han Shen,1 Xiaoli Cao1 1Department of Laboratory Medicine, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu, People’s Republic of China; 2Nanjing Field Epidemiology Training Program, Nanjing Municipal Center for Disease Control and Prevention, Nanjing, Jiangsu, People’s Republic of China; 3Department of Laboratory Medicine, The Affiliated Fuyang Hospital of Anhui Medical University, Fuyang, Anhui, People’s Republic of China; 4Nanjing Jiangning District Center for Disease Control and Prevention, Nanjing, Jiangsu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiaoli Cao; Han Shen, Email cao-xiao-li@163.com; shenhan10366@sina.comObjective: This study aimed to analyze the antimicrobial resistance profiles, clinical characteristics and risk factors of bacteremia caused by Enterobacter cloacae complex (ECC) strains.Methods: We retrospectively collected clinical data from patients diagnosed with ECC bacteremia between 2013 and 2022 in a tertiary hospital in Jiangsu. …”
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Probiotic Potential of Lactic Acid Starter Cultures Isolated from a Traditional Fermented Sorghum-Millet Beverage by Stellah Byakika, Ivan Muzira Mukisa, Yusuf Byenkya Byaruhanga, Charles Muyanja

“…The cultures were examined for tolerance to acid and bile salts, bile salt hydrolase (BSH) activity, antibiotic susceptibility, biogenic amine production, mucin degradation, hydrophobicity, auto-aggregation, adherence to the ileum, coaggregation, and antimicrobial properties against selected pathogenic species. …”
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Haploidentical stem cell transplantation with posttransplant cyclophosphamide in children with Wiskott–Aldrich syndrome: a case report by Le Nguyen Ngoc Quynh, Binh Nguyen Thanh, Lien Luong Thi, Thuy Nguyen Thi Dieu, Duong Dang Anh, Pamela P. Lee, Tung Cao Viet, Dien Tran Minh

“…He received immunoglobulin replacement therapy and antimicrobial prophylaxis and underwent HSCT at 4 years 3 months of age. …”
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Bacterial isolates and drug susceptibility patterns in infected lesions of cutaneous leishmaniasis patients at ALERT hospital, Addis Ababa, Ethiopia by Gizealew Ayalew, Asegedech Asmamaw, Mistire Wolde, Regasa Diriba, Biruk Zerfu

“…The isolates were identified by gram staining, colony morphology, and biochemical testing. Antimicrobial susceptibility patterns were done using the disk diffusion technique according to 2021 CLSI guidelines. …”
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Potential Medicinal Fungi from Freshwater Environments as Resources of Bioactive Compounds by Ilenia Cicero, Giulia Mirabile, Giuseppe Venturella

“…Among them, macrofungi, such as <i>Amanita vaginata</i>, <i>Armillaria mellea</i>, <i>Armillaria tabescens</i>, <i>Astraeus hygrometricus</i>, <i>Auricularia auricula-judae</i>, <i>Bjerkandera adusta</i>, <i>Bovista nigrescens</i>, <i>Calocybe gambosa</i>, <i>Candolleomyces candolleanus</i>, <i>Collybia dryophila</i>, <i>Coprinus comatus</i>, <i>Cyclocybe cylindracea</i>, <i>Hypsizygus ulmarius</i>, <i>Inonotus hispidus</i>, <i>Lactarius controversus</i>, <i>Lentinus tigrinus</i>, and <i>Schizophyllum commune</i>, observed in riparian habitat, and microfungi, such as <i>Penicillium aculeatum</i>, <i>P. chrysogenum</i>, and <i>Fusarium incarnatum</i>, isolated from aquatic plants, have been reported to have antimicrobial, anticancer, anti-inflammatory, antioxidant, antidiabetic, immunomoludatory, hypoglycaemic, and other pharmaceutical activities. …”
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Molecular characterization and therapeutic insights into biofilm positive Staphylococcus aureus isolated from subclinical mastitis in dairy buffaloes by Muhammad Ijaz, Muhammad Umar Javed, Arslan Ahmed

“…The combinations of resistant antibiotics with non-antibiotics were investigated using the well diffusion method and checkerboard assay. Antimicrobial effects of non-antibiotics against study isolates accessed through the well diffusion method showed higher inhibition zones for meloxicam followed by flunixin, ketoprofen, and ivermectin. …”
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Microalga <i>Nannochloropsis gaditana</i> as a Sustainable Source of Bioactive Peptides: A Proteomic and In Silico Approach by Samuel Paterson, Laura Alonso-Pintre, Esperanza Morato-López, Sandra González de la Fuente, Pilar Gómez-Cortés, Blanca Hernández-Ledesma

“…Among them, 27 exhibited theorical antioxidant, antihypertensive, antidiabetic, anti-inflammatory, and/or antimicrobial activities. Seven of twenty-seven peptides showed ≥20% intestinal absorption, suggesting potential systemic effects, while the rest could act at local level. …”
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Biofilm as a supracellular organization of pathogenic bacteria by B.P. Kuzminov, K.D. Mazhak

“…The search for new active substances with anti-biofilm activity based on the analysis of literature data on the structure of bacterial biofilms, mechanisms of their resistance to antimicrobial agents was the purpose of this work. An electronic search was conducted in Medline (PubMed interface), Scopus, and Web of Science between 2011 and July, 2024 using the keywords: biofilms, antibiotic resistance, Quorum sensing, persisters. 30 sources were selected, 85 were processed. …”
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Analysis of factors affecting the clinical management of infection in culture-negative patients following percutaneous endoscopic decompression: a retrospective study by Changpeng Qu, Haixin Wei, Hao Zhang, Zheng Lian, Hui Lu, Shuo Han

“…This study retrospectively analyzed the medical records of culture-negative patients following percutaneous endoscopic surgery to identify risk factors influencing antimicrobial therapy and provide insights for clinical management.MethodsData were retrospectively collected from patients who underwent lumbar percutaneous endoscopic decompression at the Affiliated Hospital of Qingdao University between January 2014 and June 2023. …”
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Community pharmacies: Key players in point-of-care diagnostics for STI screening in Africa. by Agnes N Kiragga, Annet Onzia, Vivian Nakate, Irene Bagaya, Evelyn Natuha, Emmanuel Mande, Olivia Kataike, Rosalind Parkes-Ratanshi, Matthew M Hamill, Yukari C Manabe

“…<h4>Conclusion</h4>Our research underscores the potentially pivotal role of community pharmacies in deploying POC diagnostics for STIs and antimicrobial stewardship by decreasing unnecessary antibiotic dispensation across Africa.…”
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Jamun Seed: A Review on Bioactive Constituents, Nutritional Value and Health Benefits by Yamini Tak, Manpreet Kaur, Mool C. Jain, Mahesh Kumar Samota, Nirmal Kumar Meena, Gurpreet Kaur, Rajendra Kumar, Daisy Sharma, José M. Lorenzo, Ryszard Amarowicz

“…These seeds are a potential source of bioactive compounds including hydrolysable tannins, phenolic acids, flavonoids, other phenolics, terpenoids, phloroglucinol derivatives and saponins, which have been endorsed several biological activities, such as antidiabetic, anticancer, anti-inflammatory, antioxidant, antimicrobial, antihyperlipidemic and antihypercholesterolemic, as well as cardioprotective, hepatoprotective and neuroprotective properties. …”
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Assessments of Antibacterial Effects of Aqueous-Ethanolic Extracts of Sida rhombifolia’s Aerial Part by Demeke Debalke, Mastewal Birhan, Amebaye Kinubeh, Muluken Yayeh

“…Infectious diseases are the critical problems of the world as a result of the emergence of different antimicrobial resistant microorganisms due to several reasons like misuses and repeating uses of antibiotics. …”
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Development of Alginate-Chitosan Bioactive Films Containing Essential Oils for Use in Food Packaging by Carla Guzmán-Pincheira, Arash Moeini, Patricia E. Oliveira, Diana Abril, Yeni A. Paredes-Padilla, Sergio Benavides-Valenzuela

“…On average, the increase from 1.0% to 3.0% of EOO increased the antimicrobial capacity against Gram-negative and Gram-positive bacteria. …”
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Structural characteristics, functions, and counteracting strategies of biofilms in Staphylococcus aureus by Yanze Xia, Zhenghui Hu, Qiyuan Jin, Qi Chen, Chenhao Zhao, Rui Qiang, Zonggang Xie, Liubing Li, Haifang Zhang

“…It also analyses the protective mechanisms that fortify S. aureus biofilms against antimicrobial treatments. Furthermore, the review provides a comprehensive overview of recent therapeutic innovations, including enzymatic therapy, nanotechnology, gene editing, and phage therapy. …”
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Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament by Emmajay Sutherland, Christopher J. Harding, Tancrède du Monceau de Bergendal, Gordon J. Florence, Katrin Ackermann, Bela E. Bode, Silvia Synowsky, Ramasubramanian Sundaramoorthy, Clarissa Melo Czekster

“…Abstract Cyclic dipeptides are produced by organisms across all domains of life, with many exhibiting anticancer and antimicrobial properties. Oxidations are often key to their biological activities, particularly C-C bond oxidation catalysed by tailoring enzymes including cyclodipeptide oxidases. …”
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