Antimalarial Activity of Piperine by Artitaya Thiengsusuk, Phunuch Muhamad, Wanna Chaijaroenkul, Kesara Na-Bangchang

“…Piperine could be a promising candidate for further development as an antimalarial drug based on its antimalarial potency and low risk of resistance development.…”
Get full text

Review of Atypical Organometallic Compounds as Antimalarial Drugs by Samuel K. Kwofie, Emmanuel Broni, Bismark Dankwa, Kweku S. Enninful, Joshua Teye, Cedar R. Davidson, Josephine B. Nimely, J. Chioma Orizu, Prakasha Kempaiah, Brijesh Rathi, Whelton A. Miller

“…Due to resistance of the Plasmodium parasite to traditional organic antimalarials, the use of organometallic compounds has become widely adopted in antimalarial drug discovery. …”
Get full text

Cytotoxic and Antioxidant Effects of Antimalarial Herbal Mixtures by Isaac Dadzie, Shaibu Adams Avorgbedo, Regina Appiah-Opong, Obed Cudjoe

“…The aim of the study was to determine the cytotoxic and antioxidant effects of five different antimalarial herbal mixtures. Five antimalarial herbal mixtures commonly used in Ghana (coded as STF, SMH, SMM, SGM, and STT) were purchased and freeze-dried. …”
Get full text

Natural Products as Sources of Antimalarial Drugs: Ethnobotanical and Ethnopharmacological Studies by Oluwole Solomon Oladeji, Abimbola Peter Oluyori, Deborah Temitope Bankole, Tokunbo Yemisi Afolabi

“…The study explores the ethnobotanical and ethnopharmacological appraisal of antimalarial plants used by people of Omu Aran, Ogbomoso, Ado Ekiti, and Sagamu communities in Nigeria. …”
Get full text

Antimalarial Activity of Extract and Fractions of Sauropus androgynus (L.) Merr. by Wiwied Ekasari, Dwi Fatmawati, Siti M. Khoiriah, Wenda A. Baqiuddin, Hawi Q. Nisa, Adinda A. S. Maharupini, Tutik S. Wahyuni, Rice D. Oktarina, Eko Suhartono, Ram K. Sahu

“…Based on genus and chemotaxonomic approaches, as well as in vitro testing of Plasmodium falciparum, leaves of S. androgynus are presumed to have an active compound content as an antimalarial. The current study aims to investigate the antimalarial activity of 96% ethanol extract and fractions of S. androgynus leaves. …”
Get full text

Synthesis and Evaluation of Some New Isoquine Analogues for Antimalarial Activity by Chandra Nath Saha, Sanjib Bhattacharya, Dipak Chetia

“…Amodiaquine is a 4-aminoquinoline antimalarial that can cause adverse side effects including hepatic and haematological toxicity. …”
Get full text

Home management of malaria among caregivers of under-five children in Owo, Ondo State, Nigeria by Liasu Adeagbo Ahmed, Olubankole Akinboboye, Olayinka Stephen Ilesanmi, David Akintayo Oguntuase

Subjects: “…Antimalarials…”
Get full text

Phytochemical Analysis and Antimalarial Activity Aqueous Extract of Lecaniodiscus cupanioides Root by Mikhail Olugbemiro Nafiu, Taoheed Adedeji Abdulsalam, Musbau Adewumi Akanji

“…Root aqueous extract of Lecaniodiscus cupanioides was evaluated for antimalarial activity and analyzed for its phytochemical constituents. …”
Get full text

Antimalarial Activity of Tinospora baenzigeri against Plasmodium berghei-Infected Mice by Sakaewan Ounjaijean, Manas Kotepui, Voravuth Somsak

“…Plant species of the genus Tinospora (Menispermaceae) possess several pharmacological properties, and T. crispa has been reported to have antimalarial activity. T. baenzigeri (Chingcha Chalee) is a rich source of terpenes and quinoline alkaloids; however, it still has not yet been investigated the antimalarial activity of this plant extract. …”
Get full text

A reaction-diffusion system modeling the spread of resistance to an antimalarial drug by Nicolas Bacaër, Cheikh Sokhna

“…A mathematical model representing the diffusion of resistance toan antimalarial drug is developed. Resistance can spread only whenthe basic reproduction number of the resistant parasites is biggerthan the basic reproduction number of the sensitive parasites(which depends on the fraction of infected people treated with theantimalarial drug). …”
Get full text

Efficient One-Pot Synthesis of Novel Caffeic Acid Derivatives as Potential Antimalarials by Katarzyna Sidoryk, Silvia Parapini, Nicoletta Basilico, Magdalena Zaremba-Czogalla, Marek Kubiszewski, Marcin Cybulski, Jerzy Gubernator, Agnieszka Zagórska, Anna Jaromin

“…It allows for an easy increase of input data to refine the structure-activity relationship model of caffeates as the antimalarials. The one-step approach meets the conditions of “atom economy” and eliminates hazardous materials. …”
Get full text

Development and experimental validation of a machine learning model for the prediction of new antimalarials by Mukul Kore, Dimple Acharya, Lakshya Sharma, Shruthi Sridhar Vembar, Sandeep Sundriyal

“…Abstract A large set of antimalarial molecules (N ~ 15k) was employed from ChEMBL to build a robust random forest (RF) model for the prediction of antiplasmodial activity. …”
Get full text

Discovery of Antimalarial Drugs from Streptomycetes Metabolites Using a Metabolomic Approach by Siti Junaidah Ahmad, Mohd Badrin Hanizam Abdul Rahim, Syarul Nataqain Baharum, Mohd Shukri Baba, Noraziah Mohamad Zin

“…Recently, by using a bioassay-guided fractionation, an antimalarial compound, Gancidin-W, has been discovered from these bacteria. …”
Get full text

Recent approaches in the drug research and development of novel antimalarial drugs with new targets by Chinnappanna Naveen Kumar Reddy, Yennam Gopi, Chaitanya Chaitanya Budagam Haima Naga Venkata, Pottathil Shinu, Borah Pobitra, Venugopala Katharigatta N., Deb Pran Kishore, Mailavaram Raghu Prasad

Subjects: “…antimalarial drugs…”
Get full text

Serine Proteases of Malaria Parasite Plasmodium falciparum: Potential as Antimalarial Drug Targets by Asrar Alam

“…Widespread drug resistance against currently available antimalarials warrants the identification of novel drug targets and development of new drugs. …”
Get full text

Formulation and In Vitro Evaluation of Oral Capsules from Liquid Herbal Antimalarials Marketed in Ghana by Christina Osei-Asare, Fredrick William Akuffo Owusu, Philomena Entsie, Ama Kwansima Annan, Rita Akosua Gyamaa, Edem Makafui Amenuke

“…The patronage and usage of liquid herbal antimalarials in the management and treatment of malaria in Ghana have been on the ascendency over the past decade. …”
Get full text

Acute Oral Toxicity, Histopathological Analysis, and Antimalarial Potential of Jatropha tanjorensis Leaf Extracts by Fatima Jumare, Helen Ileigo Inabo, Muhammad Hassan Isa Doko, Gbonjubola Olusesan Adeshina

Subjects: Get full text

The Potential use of a Curcumin-Piperine Combination as an Antimalarial Agent: A Systematic Review by Shafia Khairani, Nisa Fauziah, Hesti Lina Wiraswati, Ramdan Panigoro, Endang Yuni Setyowati, Afiat Berbudi

“…Malaria remains a significant global health problem, but the development of effective antimalarial drugs is challenging due to the parasite’s complex life cycle and lack of knowledge about the critical specific stages. …”
Get full text

Nanoparticles of beetroot extract: A potential antimalarial adjuvant in Plasmodium berghei-infected mice by Fransisca Pramesshinta Hardimarta, Lisyani Budipradigda Suromo, Kis Djamiatun

“…The findings of the study suggest that nanoparticles of beetroot extract could have potential as an anti-inflammatory and antimalarial adjuvant for malaria infection. [ J Adv Biotechnol Exp Ther 2025; 8(1.000): 55-63]…”
Get full text

Antimalarial Combination Therapies Increase Gastric Ulcers Through an Imbalance of Basic Antioxidative‑Oxidative Enzymes in Male Wistar Rats. by Kalange, Muhamudu, Nansunga, Miriam, Keneth Iceland, Kasozi, Kasolo, Josephine, Namulema, Jackline, Kasande Atusiimirwe, Jovile, Tiyo Ayikobua, Emanuel, Ssempijja, Fred, Munanura, Edson Ireeta, Matama, Kevin, Semuyaba, Ibrahim, Zirintunda, Gerald Gerald, Okpanachi, Alfred Omachonu

Subjects: “…Antimalarials…”
Get full text