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1781
The Role of Sulfatides in Liver Health and Disease
Published 2025-01-01“…Sulfatides are self-lipid antigens presented by cholangiocytes to activate cluster of differentiation 1d (CD1d)-restricted type II natural killer T (NKT) cells. …”
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1782
Rituximab for Autoimmune Encephalitis with Epilepsy
Published 2020-01-01“…It is characterized by antibodies against cerebral antigens, such as potassium channels such as leucine-rich, glioma inactivated 1 (LGI1) and contactin-associated protein 2 (CASPR2), calcium channels such as the voltage-gated calcium channel (VGCC), or neurotransmitter receptors such as the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR), gamma aminobutyric acid receptor (GABAR), and N-methyl-D-aspartate receptor (NMDAR). …”
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1783
Computer-Aided Design of an Epitope-Based Vaccine against Epstein-Barr Virus
Published 2017-01-01“…The T cell component includes 14 CD8 T cell epitopes from early antigens and 4 CD4 T cell epitopes, targeted during the course of a natural infection and providing a population protection coverage of over 95% and 81.8%, respectively. …”
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1784
ACE2 : S1 RBD Interaction-Targeted Peptides and Small Molecules as Potential COVID-19 Therapeutics
Published 2021-01-01“…The COVID-19 pandemic that began in late 2019 continues with new challenges arising due to antigenic drift as well as individuals who cannot or choose not to take the vaccine. …”
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1785
CALENDARIO POLÍNICO DE ESPECIES POTENCIALMENTE ALERGÓGENAS Y SU RELACIÓN CON PARÁMETROS METEOROLÓGICOS EN VILLA VENTANA, PROVINCIA DE BUENOS AIRES
Published 2014-12-01“…If a plant contains antigens capable of triggering an anaphylactic phenomenon in the human body it must be considered allergenic. …”
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1786
Canine parvovirus enteritis: epidemic situation analysis and perspectives
Published 2021-01-01“…One of the main biological properties of parvovirus is its continuous genetic evolution, which led to the replacement of the original virus type by new antigenic variants – CPV-2a, CPV-2b and CPV-2c. According to the literature data, all three variants of the virus are currently circulating in the domestic dog population worldwide. …”
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1787
Characterization of the Protective HIV-1 CTL Epitopes and the Corresponding HLA Class I Alleles: A Step towards Designing CTL Based HIV-1 Vaccine
Published 2014-01-01“…High mutation rate in the viral genome underlying the antigenic variability of the viral proteome is the major hindrance as far as the antibody based vaccine development is concerned. …”
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1788
Monocyte Subsets in Schistosomiasis Patients with Periportal Fibrosis
Published 2014-01-01“…A major issue with Schistosoma mansoni infection is the development of periportal fibrosis, which is predominantly caused by the host immune response to egg antigens. Experimental studies have pointed to the participation of monocytes in the pathogenesis of liver fibrosis. …”
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1789
HIFU-CCL19/21 Axis Enhances Dendritic Cell Vaccine Efficacy in the Tumor Microenvironment
Published 2025-01-01“…Methods: M-HIFU was applied to induce immunogenic cell death by mechanically disrupting tumor cells, releasing tumor-associated antigens and creating an immunostimulatory environment. …”
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1790
Gamma delta T cells in acute myeloid leukemia: biology and emerging therapeutic strategies
Published 2024-02-01“…These cells represent a minor population of T lymphocytes with intrinsic abilities to recognize antigens in a major histocompatibility complex-independent manner and functionally straddle the innate and adaptive immunity interface. …”
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1791
Leptospira and Inflammation
Published 2012-01-01“…Although the virulence factors, molecular targets, mechanisms of inflammation, and signaling pathways triggered by leptospiral antigens have been studied, some questions are still unanswered. …”
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1792
Comparison of Gene Expression in Human Embryonic Stem Cells, hESC-Derived Mesenchymal Stem Cells and Human Mesenchymal Stem Cells
Published 2011-01-01“…Transcript analysis of membrane antigens suggests that IL1R1low, BMPR1Blow, FLT4low, LRRC32low, and CD34 may be good candidates for the detection and isolation of the most primitive hMSCs. …”
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1793
Simulating Immune Interference on the Effect of a Bivalent Glycoconjugate Vaccine against Haemophilus influenzae Serotypes “a” and “b”
Published 2016-01-01“…We developed a stochastic simulation model of humoral immune response to investigate the antigenic challenge of a bivalent combined glycoconjugate vaccine and a bivalent unimolecular glycoconjugate vaccine. …”
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1794
Immunotherapy for Hepatocellular Carcinoma: Current Advances and Future Expectations
Published 2018-01-01“…Cancer vaccination is performed using antigenic substances to activate tumor-specific immune responses. …”
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1795
Intelligence algorithm for the treatment of gastrointestinal diseases based on immune monitoring and neuroscience: A revolutionary tool for translational medicine
Published 2025-02-01“…A multi universe optimized BP neural network model was implemented based on TCGA data of common immune antigens in clinical laboratories. The working mechanism of this model is to assign values to the parameters of the BP neural network by using the process of searching for the best fitness in multiple universes. …”
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1796
Temperature Depended Role of Shigella flexneri Invasion Plasmid on the Interaction with Acanthamoeba castellanii
Published 2012-01-01“…The virulence genes required for invasion are clustered on a large 220 kb plasmid encoding type three secretion system (TTSS) apparatus and virulence factors such as adhesions and invasion plasmid antigens (Ipa). The bacterium is transmitted by contaminated food, water, or from person to person. …”
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1797
Antibodies from a Patient with Type 1 Diabetes and Celiac Disease Bind to Macrophages that Express the Scavenger Receptor CD163
Published 2011-01-01“…Antibodies against the wheat storage globulin Glo-3A from a patient with both type 1 diabetes (T1D) and celiac disease were enriched to identify potential molecular mimicry between wheat antigens and T1D target tissues. Recombinant Glo-3A was used to enrich anti-Glo-3A immunoglobulin G antibodies from plasma by batch affinity chromatography. …”
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1798
Ways to improve the gene pool of pigs of the Russian Federation
Published 2019-01-01“…The positive effect of breeding pigs in a closed mode in the form of a “line-population”, using such genetic markers as erythrocyte antigens, erythrocyte enzymes, lipoproteins, allowing intensifcation of the selection process, has been experimentally proved. …”
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1799
A population model capturing dynamics of tuberculosis granulomas predicts host infection outcomes
Published 2015-01-01“…The model also predicts a dual role for granuloma development in LNs during Mtb infection: in early phases of infection granulomas suppress infection by providing additional antigens to the site of immune priming; however, this induces a more rapid reactivation at later stages by disrupting immune responses. …”
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1800
Cancer-Associated Immune Resistance and Evasion of Immune Surveillance in Colorectal Cancer
Published 2016-01-01“…Recent works reveal that expression of immune antigens (PDL1, CD47, CD73, CD14, CD68, MAC387, CD163, DAP12, and CD15) by tumor cells “immune resistance,” combined with prometastatic function of nonmalignant infiltrating cells, may represent a strategy to overcome the rate-limiting steps of metastatic cascade through (a) enhanced interactions with protumorigenic myeloid cells and escape from T-dependent immune response mediated by CD8+ and natural killer (NK) cells; (b) production of immune mediators that establish a local and systemic tumor-supportive environment (premetastatic niche); (c) ability to survive either in the peripheral blood as circulating tumor cells (CTCs) or at the metastatic site forming a cooperative prometastatic loop with foreign “myeloid” cells, macrophages, and neutrophils, respectively. …”
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