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1561
CoviWall, a whole-virion-inactivated B.1.617.2 vaccine candidate, induces potent humoral and Th1 cell response in mice and protects against B.1.617.2 strain challenge in Syrian ham...
Published 2025-01-01“…Although most of the vaccines were developed initially with the ancestral Wuhan antigen, here, we report the development and immunological efficacy of a whole-virion–inactivated vaccine candidate (CoviWall) to combat the deadly B.1.617.2 (Delta strain) infection. …”
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1562
Development and validation of predictive models of early immune effector cell–associated hematotoxicity
Published 2025-02-01“…Abstract: Immune effector cell–associated hematotoxicity (ICAHT) is associated with morbidity and mortality after chimeric antigen receptor (CAR) T-cell therapy. To date, the factors associated with ICAHT are poorly characterized, and there is no validated predictive model of ICAHT as defined by current consensus criteria. …”
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1563
Intratumoral pan-ErbB targeted CAR-T for head and neck squamous cell carcinoma: interim analysis of the T4 immunotherapy study
Published 2023-06-01“…To target upregulated ErbB dimer expression in this cancer, we developed an autologous CD28-based chimeric antigen receptor T-cell (CAR-T) approach named T4 immunotherapy. …”
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1564
Análisis de genotipos, alelos y haplotipos de HLA en un grupo de pacientes con artritis psoriásica: poca frecuencia de alelos comunes
Published 2024-12-01“…La artritis psoriásica es una enfermedad compleja y los antígenos leucocitarios humanos (Human Leukocyte Antigen, HLA) son un factor clave en el desarrollo de la enfermedad. …”
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1565
Development of a clinical decision support tool for Primary care Management of lower Urinary tract Symptoms in men: the PriMUS study
Published 2025-01-01“…Age, voiding symptoms subscore, prostate-specific antigen level, median maximum flow rate, median voided volume were predictors for bladder outlet obstruction. …”
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1566
Comprehensive epidemiological evaluation of ruminant brucellosis and associated risk factors in some Egyptian Governorates
Published 2025-12-01“…The buffered acidified plate antigen test (BAPAT), Rose Bengal plate test (RBPT), and complement fixation test (CFT) were used for serological diagnosis of brucellosis. …”
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1567
Delivery of dendritic cells targeting 3M2e-HA2 nanoparticles with a CpG adjuvant via lysosomal escape of Salmonella enhances protection against H9N2 avian influenza virus
Published 2025-01-01“…HA2, the neck of the HA protein, and M2e, the extracellular N-terminal structural domain of the M2 protein, are conserved and effective protective antigens.In this study, the HA2 sequences were fused with three M2e copies (H9N2, H1N1 and H5N1) to the norovirus VP1 protein via the SpyTag-SpyCatcher platform to form self-assembled nanoparticles and display antigenic proteins on its surface, yielding pYL262. …”
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1568
Acute hepatitis of non-specified etiology
Published 2011-02-01“…To estimate pathogenic and diagnostic value of detection of hepatotropic viruses components (DNA, RNA, antigens) and antiviral immune response at acute hepatitis of non-specified etiology by the methods of enzyme-linked immunoassay (EIA), polymerase chain reaction (PCR) and Т-cellular lymphocytes proliferation in response to HCV antigens stimulation.Methods. …”
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1569
Candidate vaccine construction against tick-born encephalitis based on hybrid recombinant flagG-protE-protein
Published 2018-01-01“…This indicates that the investigated recombinant protein has an antigenic structure similar to the antigenic structure of the native tickborne encephalitis virus protein E. …”
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1570
Comparative testing of vaccines based on viruses of genetic lineages G1 and Y280 for their potency against low pathogenic avian influenza H9N2
Published 2021-08-01“…It was demonstrated that due to antigenic and immunogenic differences between LPAI H9N2 strains, use of both antigenic components in the inactivated vaccines is appropriate.…”
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1571
Immunogenic Targets for Specific Immunotherapy in Multiple Myeloma
Published 2012-01-01“…Several tumor-associated antigens have been identified in patients with multiple myeloma. …”
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1572
Autoimmunity against cytokines: Double strike in autoimmune disease, a historical perspective
Published 2024-12-01“…Autoimmune responses are characterized by the development of antibodies and the activation of T lymphocytes against self-antigens. This leads to an effector immune response against tissues expressing antigens, which are later recognized by the host immune system. …”
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1573
Hypersensitivity Pneumonitis: Challenges of a Complex Disease
Published 2024-01-01“…An impressive number of inciting antigens causing hypersensitivity pneumonitis have been found to cover a wide range of occupations. …”
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1574
A Novel Insight into the Role of PLA2R and THSD7A in Membranous Nephropathy
Published 2021-01-01“…Membranous nephropathy (MN) is an organ-restricted autoimmune disease mainly caused by circulating autoantibodies against podocyte antigens, including the M-type phospholipase A2 receptor (PLA2R) and thrombospondin domain-containing 7A (THSD7A). …”
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1575
Rapid Diagnosis of Intestinal Parasitic Protozoa, with a Focus on Entamoeba histolytica
Published 2009-01-01“…Detection of specific E. histolytica antigens in stools is a fast, sensitive technique that should be considered as the method of choice. …”
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1576
Fitness costs of Mycobacterium tuberculosis resistant to rifampicin is compensated by rapid Th2 polarization mediated by early and high IL-4 production during mice infection
Published 2025-01-01“…The proteins correspond to surface antigens, virulence factors, and energy metabolism enzymes. …”
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1577
Designing of an innovative conserved multiepitope subunit vaccine targeting SARS-CoV-2 glycoprotein and nucleoprotein through immunoinformatic
Published 2025-01-01“…The multi-epitope construct successfully passed three-fold toxicity, allergenicity, and antigenicity tests, affirming its non-toxic, non-allergenic, and antigenic nature. …”
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1578
Transplantation Tolerance Induced in Humans at the Fetal or the Neonatal Stage
Published 2011-01-01“…Numerous T-cells recognizing the allogeneic, host-type antigens are identified in these patients, but these cells are anergized, following interaction with epithelial cells of the host thymus. …”
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1579
The Humoral Theory of Transplantation: Epitope Analysis and the Pathogenicity of HLA Antibodies
Published 2016-01-01“…Central to the humoral theory of transplantation is production of antibodies by the recipient against mismatched HLA antigens in the donor organ. Not all mismatches result in antibody production, however, and not all antibodies are pathogenic. …”
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1580
Precolostral antibody reactivity against Histophilus somni conserved proteins and Escherichia coli whole cells in stillborn and live calves
Published 2025-03-01“…We hypothesized that antibodies (Ab) that react with bacterial antigens are common in fetuses. Plasma samples from 121 stillborn calves were used as the experimental group and 21 live-born healthy calves were used as the control group. …”
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