An innovative method used for the identification of N-glycans on soybean allergen β-conglycinin by Cheng Li, Yang Tian, Jianli Han, Yu Lu, Meiyi Zou, Yue Jia, Chengjian Wang, Linjuan Huang, Zhongfu Wang

“…N-Glycans attached to the β-conglycinin influenced the immunoreactivity and antigen presenting efficiency of β-conglycinin. In this study, we described a new method used to release and collect the N-glycans from β-conglycinin, and the N-glycans existed in linear epitopes of β-conglycinin were identified. …”
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Does bladder outflow obstruction obfuscate the traditional clinical factors that are used to assess the risk of prostate cancer at rapid‐access diagnostic clinics? by Thomas Philip Cahill, Samuel Joseph Withey, Steve Hazell, Declan Cahill, Netty Kinsella

“…Abstract Objectives To understand whether bladder outflow obstruction influences the association between traditional clinical predictive factors, particularly prostate‐specific antigen (PSA) density and clinically significant prostate cancer (csPCa). …”
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The role of dendritic cells in tertiary lymphoid structures: implications in cancer and autoimmune diseases by Mariana Reste, Kristi Ajazi, Ayca Sayi-Yazgan, Ayca Sayi-Yazgan, Radmila Jankovic, Biljana Bufan, Sven Brandau, Espen S. Bækkevold, Florent Petitprez, Malin Lindstedt, Gosse J. Adema, Catarina R. Almeida

“…Central to the function of TLS are DCs, professional antigen-presenting cells (APCs) that coordinate the adaptive immune response, and which can be classified into different subsets, with specific functions, and markers. …”
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Mapping the global landscape of chikungunya rapid diagnostic tests: A scoping review. by José Moreira, Patrícia Brasil, Sabine Dittrich, André M Siqueira

“…The sensitivity of the antigen RDTs ranged from 33.3% to 100%.<h4>Conclusions</h4>The landscape of CHIKV RDTs is fragmented and needs coordinated efforts to ensure that patients in CHIKV-endemic areas have access to appropriate RDTs. …”
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Anti-DENV-ED3 antibody cross-talks generate immune interference among the four DENVs by Md. Din Islam, Sanjida Yesmin, Tahmina Sharmin, Md. Ayoub Khan, Yutaka Kuroda, M. Monirul Islam

“…Such intrinsic features of DENV1~4 ED3s may lead to ‘antigen interference’, limiting both the understanding of dengue etiology and the success of dengue vaccine development, which needs to neutralize all four DENV serotypes equivalently.…”
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Characterization of Urine-Derived Stromal/Stem Cells from Healthy Dogs and Dogs Affected by Chronic Kidney Disease (CKD) by Anna Lange-Consiglio, Filippo Tagliasacchi, Fausto Cremonesi, Claudia Gusmara, Claudia Pollera, Paola Scarpa, Giulia Gaspari, Pietro Riccaboni

“…Cells were able to differentiate into osteogenic, chondrogenic, and adipogenic lines, showed positive expression to mesenchymal/stem markers, negative expression to hematopoietic markers, and major histocompatibility complex (MHCII) antigen. Klotho protein expression was confirmed. …”
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Improved ChIP Sequencing for H3K27ac Profiling and Super-Enhancer Analysis Assisted by Fluorescence-Activated Sorting of Formalin-Fixed Paraffin-Embedded Tissues by Nenggang Jiang, Zhihao Wen, Huan Tao, Hongyan Liao

“…Essential steps included single cell preparation, heat treatment enhancing antigen retrieval and labeling, cell sorting, chromatin shearing, ChIP and NGS. …”
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Increased Fas and Bcl-2 Expression on Peripheral Blood T and B Lymphocytes from Juvenile-Onset Systemic Lupus Erythematosus, but not from Juvenile Rheumatoid Arthritis and Juvenile... by Bernadete L. Liphaus, Maria H. B. Kiss, Solange Carrasco, Claudia Goldenstein-Schainberg

“…The aims of this study were to determine the expression of Fas antigen and Bcl-2 protein on peripheral blood T and B lymphocytes from patients with juvenile-onset systemic lupus erythematosus (JSLE), juvenile rheumatoid arthritis (JRA) and juvenile dermatomyositis (JDM). …”
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HLA-G Dimers in the Prolongation of Kidney Allograft Survival by Maureen Ezeakile, Vera Portik-Dobos, Juan Wu, Daniel D. Horuzsko, Rajan Kapoor, Muralidharan Jagadeesan, Laura L. Mulloy, Anatolij Horuzsko

“…Human leukocyte antigen-G (HLA-G) contributes to acceptance of allografts in solid organ/tissue transplantation. …”
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The Expression Level of mRNA, Protein, and DNA Methylation Status of FOSL2 of Uyghur in XinJiang in Type 2 Diabetes by Jun Li, Siyuan Li, Ying Hu, Guolei Cao, Siyao Wang, Partab Rai, Xiaoli Wang, Kan Sun

“…The expression levels of FOS-like antigen 2 (FOSL2) and the protein expression levels were analyzed. …”
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Multiomic quantification of the KRAS mutation dosage improves the preoperative prediction of survival and recurrence in patients with pancreatic ductal adenocarcinoma by Won-Gun Yun, Daeun Kim, Youngmin Han, Wooil Kwon, Seong-Geun Lee, Jin-Young Jang, Daechan Park

“…Our prognostic scoring system included the mutation dosage from targeted sequencing ( > 0.195, 1 point), maximal tumor diameter at preoperative imaging ( > 20 mm, 1 point), and carbohydrate antigen 19-9 levels ( > 150 U/mL, 1 point). The KRAS mutation dosage exhibited comparable performance with clinical variables for survival prediction. …”
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Augmented immunogenicity of the HPV16 DNA vaccine via dual adjuvant approach: integration of CpG ODN into plasmid backbone and co-administration with IL-28B gene adjuvant by Yan Zhou, Ting Zhang, Zhirong Wang, Xuemei Xu

“…Our findings revealed that mice immunized with CpG-modified vaccines, coupled with an IL-28B gene adjuvant exhibited heightened antigen-specific CD8+ T cell responses. Additionally, the combination of mE6/HSP70 and mE7/HSP70 plasmids synergistically enhanced the specific CD8+ T cell response. …”
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TMEM147 Correlates with Immune Infiltration and Serve as a Potential Prognostic Biomarker in Hepatocellular Carcinoma by Sheng Cheng, Jutang Li, Ming Xu, Qun Bao, Jiaoxiang Wu, Peng Sun, Bo Han

“…Mechanistic studies revealed that high TMEM147 expression was linked to the B lymphocyte, antigen response, IL6 signaling pathway, cell cycle, Kirsten rat sarcoma viral oncogene homolog (KRAS) signaling pathway, and myelocytomatosis oncogene (MYC) targets. …”
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Molecular Epidemiology of Human Norovirus Variants from Outbreaks in Zhejiang Province, China, during 2021 by Yi Sun, Yongjuan Yuan, Haiyan Mao, Lingxuan Su, Qiong Ge, Jian Gao, Changping Xu, Liming Gong

“…Capsid microvariation of GII.2 displayed histo-blood group antigen binding patterns compared to the GII.2 prototype, although VP1 sequences were considered to have a minimal impact on antigenicity. …”
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Antimicrobial susceptibility patterns of bacillus anthracis isolates obtained from different origins by Elif ÇELİK, Aliye GÜLMEZ SAĞLAM, Fatih BÜYÜK, Salih OTLU, Mitat ŞAHİN, Özgür ÇELEBİ, Mustafa Reha COŞKUN, Seda GÖKDEMİR, Yaren ERSOY, Eray BÜYÜK, Bengisu ERŞAHİN

“…The isolates were confirmed as B. anthracis using protective antigen (PA) and capsule (Cap) gen specific PCRs. …”
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PSMA antibody, humanized PSMA.CAR10.3, or Cetuximab increases prostate cancer localization of NF-κB p50-deficient immature myeloid cells (p50-IMC) and phagocytosis by their macroph... by Mohammad A. Alzubi, Theresa Barberi, Alan D. Friedman

“…Directing p50-IMC to tumors using Fc receptor-bound antibodies (Abs) or surface chimeric antigen receptors (CARs) may increase tumor localization and subsequent phagocytosis of cancer cells by their mature myeloid progeny, potentiating anti-tumor T cell activation. …”
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Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis by Alexandra Noble, Rodrigo Motta, Silvia Cabras, Belen Moron Flores, Jan Nowak, Aleksandra Glapa-Nowak, Alessandra Geremia, Jack Satsangi, Emma Culver

“…Epigenetic age acceleration was observed in patients with IgG4-SC, but not in those with PSC or UC. meQTL analyses to identify genetic determinants of methylation revealed a strong human leucocyte antigen (HLA) signal in both PSC and IgG4-SC (HLA-DQB2, HLA-DPA1, HLA-F and HLA-DRA). …”
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High-Fat Diet Augments VPAC1 Receptor-Mediated PACAP Action on the Liver, Inducing LAR Expression and Insulin Resistance by Masanori Nakata, Boyang Zhang, Yifei Yang, Takashi Okada, Norihito Shintani, Hitoshi Hashimoto, Toshihiko Yada

“…Using GeneFishing method, HFD increased the leukocyte common antigen-related (LAR) protein tyrosine phosphatase in the liver in wild type mice. …”
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Clinical efficacy of cytoreductive radical prostatectomy in the treatment of oligometastatic hormone-sensitive prostate cancer by Feng Qi, Yihang Xu, Zicheng Xu, Qing Zou

“…No significant differences were detected between the two groups regarding prostate-specific antigen (PSA) at the initial diagnosis (P = 0.194), the International Society of Urological Pathology (ISUP) grade group (P = 0.158), the treatment options during omHSPC (P = 0.090), common comorbidities (P = 0.649) and the number of metastases (P = 0.291). …”
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High Serum Alkaline Phosphatase Flare after First-Line Androgen Deprivation Therapy Predicts Poor Prognosis in Metastatic Prostate Cancer Patients Treated with Second-Generation An... by Satoko Kojima, Hiroshi Masuda, Takahito Suyama, Kyokushin Hou, Kousuke Mikami, Kazuhiro Araki, Yukio Naya

“…The association of the ALP flare ratio with the prostate-specific antigen (PSA) response to CRPC treatment (second-generation androgen receptor targeted therapy (ART) or docetaxel), time to CRPC, and overall survival (OS) were investigated. …”
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