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1381
Development of the test kit for detection of SARS-CoV-2 antibodies in sera of susceptible animals
Published 2021-07-01“…The use of a purified concentrated inactivated virus as an antigen allows the detection of antibodies to various SARS-CoV-2 immunodominant proteins (S and N). …”
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1382
Implementing an environmental DNA/RNA-based approach to non-invasively investigate disease caused by Ichthyophthirius multifiliis
Published 2025-03-01“…The eNA was extracted from the tank water and was used to detect the parasite throughout the course of the disease targeting a gene encoding an Ich immobilization antigen (Iag52a). Simultaneously, the parasite burden and immune-relevant gene expression in both water and fish gills were investigated. …”
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1383
Cost-effectiveness of vector control for supplementing mass drug administration for eliminating lymphatic filariasis in India.
Published 2024-12-01“…Outcomes were controlled microfilaria prevalence (MfP) and antigen prevalence (AgP) to conventional elimination targets (MfP<1% or AgP<2%) from 2010 to 2013, and modeled disability adjusted life years (DALYs) averted.…”
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1384
Plexin C1 Marks Liver Cancer Cells with Epithelial Phenotype and Is Overexpressed in Hepatocellular Carcinoma
Published 2018-01-01“…A recombinant protein encompassing part of the extracellular domain of Plexin C1 was used as an antigen for monoclonal antibody development. Transcript and protein levels of Plexin C1 in HCC cell lines were determined by RT-qPCR and Western blotting, respectively. …”
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1385
Myeloid cell-derived apCAFs promote HNSCC progression by regulating proportion of CD4+ and CD8+ T cells
Published 2025-01-01“…The origin and roles of CAFs, however, are still unclear in the HNSCC, especially antigen-presenting cancer-associated fibroblasts (apCAFs). …”
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1386
THE EFFECT OF QUERCETIN ON MORPHOLOGICAL AND BIOCHEMICAL CHANGES IN RAT LIVER UNDER 270TH DAY CENTRAL DEPRIVATION OF LUTEINIZING HORMONE SYNTHESIS
Published 2022-04-01“…The aim of our study was to determine the changes in immunocompetent liver cells, both qualitative and quantitative, caused by inhibition of central testosterone synthesis in male rats due to the introduction of triptorelin acetate on the 270th day, and the potential effect of quercetin on morphology and liver antigen-presenting cells count against the background of previous administration of triptorelin acetate solution. …”
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1387
ABA enhances the apoptotic effect of docetaxel in the multidrug-resistant DU145 prostate cancer cell line
Published 2024-01-01“…RT-PCR analysis showed that treatment of resistant cells with 50.07 nM docetaxel and 500 μM ABA (ABA) resulted in the following changes in gene expression: heat shock protein (HSP) 70 (0.63-fold), glucose-regulated protein 94 (GRP94) 0.33-fold, inositol-requiring transmembrane kinase endoribonuclease-1α (IRE1α) 1.62-fold, ER degradation- enhancing alpha-mannosidase-like 1 (EDEM1) 1.77-fold, X-box binding protein 1 (XBP1) 1.53-fold, p21 (2.53-fold), cellular tumor antigen p53 (p53) 2.49-fold, bcl-2-like protein 4 (Bax) 2.7-fold, and tumor necrosis factor (TNF-α) 6.35-fold. …”
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1388
Gallbladder Carcinomas: An Immunoprognostic Evaluation of P53; Bcl-2; CEA and Alpha-Fetoprotein
Published 2000-01-01“…Twenty-eight cases were randomly selected to evaluate the expression of P53, Bcl-2, carcinoembryonic antigen (CEA) and alpha-fetoprotein, in both the in situ (19 cases) and invasive components (28 cases) of the tumour by the avidin-biotin complex method of immunohistochemistry. …”
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1389
Shared genetic factors and the interactions with fresh fruit intake contributes to four types squamous cell carcinomas.
Published 2024-01-01“…High resolution human leucocyte antigen (HLA) alleles and corresponding amino acid sequences were imputed using SNP2HLA and tested for association with SCCs. …”
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1390
HuR Plays a Positive Role to Strengthen the Signaling Pathways of CD4+ T Cell Activation and Th17 Cell Differentiation
Published 2021-01-01“…After antigen and/or different cytokine stimulation, CD4+ T cells activated and differentiated into distinct T helper (Th) cells via differential T cell signaling pathways. …”
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1391
Scatter Artifact with Ga-68-PSMA-11 PET: Severity Reduced With Furosemide Diuresis and Improved Scatter Correction
Published 2018-11-01“…Purpose: To assess the utility of furosemide diuresis and the role of an improved scatter correction algorithm in reducing scatter artifact severity on Ga-68- Prostate-specific membrane antigen (PSMA)-11 positron emission tomography (PET). …”
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1392
Sipuleucel-T and Androgen Receptor-Directed Therapy for Castration-Resistant Prostate Cancer: A Meta-Analysis
Published 2016-01-01“…However, treatment with sipuleucel-T did not improve time-to-progression and reduction of prostate-specific antigen (PSA) level ≥50% was not significantly different from that with placebo. …”
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1393
Pan-caspase inhibitors induce secretion of HIV-1 latency reversal agent lymphotoxin-alpha from cytokine-primed NK cells
Published 2025-02-01“…Natural killer (NK) cells, with their ability to mediate cytotoxicity independent of antigen specificity, offer a promising avenue for enhancing the shock-and-kill approach. …”
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1394
Citrullinated Autoantigen–Specific T and B Lymphocytes in Rheumatoid Arthritis: Focus on Follicular T Helper Cells and Expansion by Coculture
Published 2025-01-01“…We have established novel assays to assess immune cell subpopulations, including citrullinated antigen–specific (CAS) autoreactive B and T lymphocytes, in patients with RA. …”
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1395
A Cross-Sectional Study of the Association between Autoantibodies and Qualitative Ultrasound Index of Bone in an Elderly Sample without Clinical Autoimmune Disease
Published 2018-01-01“…Serum samples were assayed for a panel of autoantibodies (anti-nuclear, extractable nuclear antigen, anti-neutrophil cytoplasmic, thyroid peroxidase, tissue transglutaminase, anti-cardiolipin, rheumatoid factor, and cyclic citrullinated peptide). …”
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1396
Establishment of a Model of Microencapsulated SGC7901 Human Gastric Carcinoma Cells Cocultured with Tumor-Associated Macrophages
Published 2018-01-01“…Immunocytochemistry confirmed that Proliferating Cell Nuclear Antigen (PCNA) and Vascular Endothelial Growth Factor (VEGF) were expressed in microencapsulated SGC7901 cells on days 7 and 14. …”
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1397
γδ T-Cell Acute Lymphoblastic Leukemia/Lymphoma: Discussion of Two Pediatric Cases and Its Distinction from Other Mature γδ T-Cell Malignancies
Published 2017-01-01“…Gamma delta (γδ) T-cell antigen receptor (TCR) expression and its related T-cell differentiation are not commonly reported in T-cell acute lymphoblastic leukemia/lymphoma (T-ALL). …”
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1398
Definition of a Novel Cuproptosis-Relevant lncRNA Signature for Uncovering Distinct Survival, Genomic Alterations, and Treatment Implications in Lung Adenocarcinoma
Published 2022-01-01“…High-risk subset displayed higher somatic mutations, CNVs, TMB, SNV neoantigens, aneuploidy score, CTA score, homologous recombination defects, and intratumor heterogeneity, cytolytic activity, CD8+ T effector, and antigen processing machinery, proving that this subset might benefit from immunotherapy. …”
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1399
Towards designing improved cancer immunotherapy targets with a peptide-MHC-I presentation model, HLApollo
Published 2024-12-01“…Abstract Based on the success of cancer immunotherapy, personalized cancer vaccines have emerged as a leading oncology treatment. Antigen presentation on MHC class I (MHC-I) is crucial for the adaptive immune response to cancer cells, necessitating highly predictive computational methods to model this phenomenon. …”
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1400
Geometry Dynamics of α-Helices in Different Class I Major Histocompatibility Complexes
Published 2015-01-01“…MHC α-helices form the antigen-binding cleft and are of particular interest for immunological reactions. …”
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