12,13-diHOME Promotes Inflammatory Macrophages and Epigenetically Modifies Their Capacity to Respond to Microbes and Allergens by Din L. Lin, Kevin M. Magnaye, Cara E. Porsche, Sophia R. Levan, Elze Rackaityte, Mustafa Özçam, Susan V. Lynch

“…We hypothesized that macrophages, which are key to both antimicrobial and antigen responses, are functionally and epigenetically modified by 12,13-diHOME leading to short- and long-term dysfunction with consequences for both antimicrobial and antigenic responses. …”
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Effect of Premna pubescens Ethanol Extract on Erythrocyte Count and Kidney Histology in Rattus norvegicus L by Srinatalia Silaen

“…Twenty-four male Wistar rats were divided into four groups: control, ethanol extract of wild leaves, Sheep Red Blood Cell (SRBC) antigen, and combined ethanol extract with SRBC. The experiment involved administering wild leaf ethanol extract at 250 mg/kg BW for 30 days, followed by SRBC injection on days 8 and 15. …”
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The Initial Experience of Trans-Rectal Ultrasound and Biopsy in Diagnosis of Carcinoma Prostate In Gezira Hospital For Renal Disease And Surgery (GHRDS) by Walaa Eldin Ibraheem, Sami Mahjoub Taha, Mustafa Omran Mansour, Mohammed El Imam Mohamed Ahmed

“…Objectives: To compare the accuracy of the Transrectal Ultrasound guided biopsy (TRUS/BX) in the diagnosis of prostate cancer in Gezira Hospital for Renal Diseases and Surgery (GHRDS), with specific considerations to the digital rectal examination (DRE) findings and prostate specific antigen (PSA) level.                      . Materials and Methods:  This is a prospective, descriptive small-scale hospital based study.  …”
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Coinfection of Hepatitis B and C Viruses and Risk of Hepatocellular Carcinoma: Systematic Review and Meta-analysis by Abdullah A. Awadh, Abdulrahman A. Alharthi, Basil A. Alghamdi, Seraj T. Alghamdi, Mohammed K. Baqays, Ibrahim S. Binrabaa, Israa A. Malli

“…We extracted the demographic characteristics, such as gender, age, study design, sample size, country, and biomarkers of hepatitis B surface antigen (HBsAg), HBV DNA, HBeAg, anti-HCV, and HCV RNA. …”
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Regulatory T Cells in the Immunodiagnosis and Outcome of Kidney Allograft Rejection by O. Franzese, A. Mascali, A. Capria, V. Castagnola, L. Paganizza, N. Di Daniele

“…Cellular rejection develops when donor alloantigens, presented by antigen-presenting cells (APCs) through class I or class II HLA molecules, activate the immune response against the allograft, resulting in activation of naive T cells that differentiate into subsets including cytotoxic CD8+ and helper CD4+ T cells type 1 (TH1) and TH2 cells or into cytoprotective immunoregulatory T cells (Tregs). …”
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Familial Russell–Silver Syndrome like Phenotype in the PCNA Domain of the CDKN1C Gene, a Further Case by A. H. Sabir, G. Ryan, Z. Mohammed, J. Kirk, N. Kiely, M. Thyagarajan, T. Cole

“…A maternally inherited pathogenic heterozygous CDKN1C variant was found in the PCNA (proliferating cell nuclear antigen) domain. Mutations of the PCNA domain of the CDKN1C gene are known to be associated with IMAGe syndrome thus with adrenal disease, although neither affected patient in our case had evidence of adrenal dysfunction. …”
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RESULTS OF EXPERIMENTAL INFECTION OF TURKEYS WITH A/DUCK/ALTAI/469/14 H5N1 STRAIN OF AVIAN INFLUENZA VIRUS by V. Yu. Sosipatorova, D. A. Altunin, I. A. Chvala, N. S. Mudrak, D. B. Andreychuk

“…Immunohistochemical analysis showed the greatest distribution of the influenza virus antigen in the cerebral endothelium, cerebellar Purkinje neurons, acinar cells of the pancreas and in myocardiocytes of the heart. …”
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Effects of Renal Denervation on Ouabain-Induced Hypertension in Rats by Minna Tang, Jialu Hu, Wenshu Li, Ningzhi Zhang, Sisi Ning, Yan Yan, Zhaoqiang Cui

“…RDN also reduced the thickening of aortic tunica media and downregulated the expression of proliferating cell nuclear antigen (PCNA) in the thoracic aorta induced by ouabain. …”
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Global research hotspots and trends in DNA vaccine research: A bibliometric and visualization study from 2014 to 2024 by Juan Zhang, Haiguo Zhang, Cuicui Yao, Lihua Gu, Shasha Dong, Yamei Wu, Lele Miao

“…Concurrently, the burst citation analysis identified emerging themes, including the development of DNA vaccines for COVID-19, Ebola, and MERS-CoV, as well as innovations in antigen design and delivery technologies. This study offers valuable insights into the evolution and future directions of DNA vaccine research, emphasizing its importance for global public health and the potential to address current and future health challenges.…”
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Nutritional changes in patients undergoing hemodialysis who develop COVID-19 by Kou Kitabayashi, Suguru Yamamoto, Shin Goto

“…COVID-19 was diagnosed using an antigen test, and the subjects were divided into COVID-19 and control groups. …”
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A lyophilised formulation of chimpanzee adenovirus vector for long-term stability outside the deep-freeze cold chain by Frédéric Mathot, Edwige Lefebvre, Bernard G. Francq, Delphine Guillaume, Erwan Bourlès

“…Methods Vaccine stability was assessed up to five years at 5 °C using a lyophilised formulation of the chimpanzee-adenovirus vector ChAd155 encoding a respiratory syncytial virus (RSV) antigen. Vaccine potency was assessed by functional infectivity assay. …”
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Etiology of Community Acquired Pneumonia at a Tertiary Care Hospital by Ritika Jha, Sumit Sengupta, Anshuman Mukhopadhyay, Ritam Chakraborty

“…Upper and lower respiratory BIOFIRE panels, sputum culture, blood culture, urinary pneumococcal antigen, and Xpert Flu were used to identify the pathogens. …”
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Construction and Antiapoptosis Activities of Recombinant Adenoviral Expression Vector Carrying EBV Latent Membrane Protein 2A by Xishuang Liu, Yu Gao, Bing Luo, Youan Zhao

“…The replication-deficient recombinant adenovirus vector can express LMP2A antigen in SGC cells and inhibit their apoptosis. …”
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Seroprevalence of hepatitis B and C virus among a group of hemophilia patients in Kurdistan Region, Iraq by Salih A. Hama

“…Methods: This prospective cross-sectional study, conducted from June to September 2022, screened 117 hemophilic patients in the region for Hepatitis B surface antigen (HBsAg) and anti-HCV antibodies using serologic assays. …”
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RIF1 integrates DNA repair and transcriptional requirements during the establishment of humoral immune responses by Eleni Kabrani, Ali Rahjouei, Maria Berruezo-Llacuna, Svenja Ebeling, Tannishtha Saha, Robert Altwasser, Veronica Delgado-Benito, Rushad Pavri, Michela Di Virgilio

“…Abstract The establishment of protective immune responses relies on the ability of terminally differentiated B cells to secrete a broad variety of antigen-specific antibodies with different effector functions. …”
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Chemical and Immunological Characteristics of Aluminum-Based, Oil-Water Emulsion, and Bacterial-Origin Adjuvants by Susana Martiñón, Angel Cisneros, Sergio Villicaña, Ricardo Hernández-Miramontes, Edgar Mixcoha, Psyché Calderón-Vargas

“…Freund’s adjuvant is the most widely used oil-water emulsion adjuvant in animal trials; it stimulates inflammation and causes aggregation and precipitation of soluble protein antigens that facilitate the uptake by antigen-presenting cells (APCs). …”
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Characteristics of ocular findings of patients with coronavirus disease 2019 in China by Shudan Wang, Jiaoyang Feng, Rui Zhu, Xin Jin, Yiheng Ding, Di Jin, Yu Guo, Hong Zhang

“…Inclusion criteria for COVID-19 was confirmed testing positive via a polymerase chain reaction (PCR) test or testing positive for COVID-19 via an antigen kit. The anonymous survey collected information on demographics, systemic COVID-19 symptoms, ocular diagnosis and symptoms, comorbidities and disease history.ResultsA total of 2,405 survey responses were collected and the final analysis included individuals in the 335 COVID-19 positive group and 434 individuals in the COVID-19 negative group. …”
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Effects of Invariant NKT Cells on Parasite Infections and Hygiene Hypothesis by Jun-Qi Yang, Yonghua Zhou, Ram Raj Singh

“…Invariant natural killer T (iNKT) cells are unique subset of innate-like T cells recognizing glycolipids. iNKT cells can rapidly produce copious amounts of cytokines upon antigen stimulation and exert potent immunomodulatory activities for a wide variety of immune responses and diseases. …”
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Optimization and Validation of Indirect ELISA Using Truncated TssB Protein for the Serodiagnosis of Glanders amongst Equines by Harisankar Singha, Praveen Malik, Sachin K. Goyal, Sandip K. Khurana, Chiranjay Mukhopadhyay, Vandana K. Eshwara, Raj K. Singh

“…These data highlight the use of TssB as potential diagnostic antigen for serological diagnosis of glanders.…”
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Impact of Obesity on Perioperative and Clinical Outcomes After Robotic Assisted Radical Prostatectomy by Sahin Kilic, Murat Sambel

“…No significant differences were observed between the groups regarding age, prostate-specific antigen (PSA) levels, or International Society of Urological Pathology (ISUP) grade distribution (p > 0.05). …”
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