C-Reactive Protein (CRP) and Autoimmune Disease: Facts and Conjectures by Alexander J. Szalai

“…Less appreciated and not as well understood as CRP's ability to bind antigen and aid in the elimination of microbes, is its known ability to bind autoantigens and presumed capacity to promote clearance of apoptotic cells. …”
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Posttranslational Modifications and the Immunogenicity of Biotherapeutics by Roy Jefferis

“…Such ICs may be removed by phagocytic cells that have antigen presenting capacity. These considerations may frustrate the possibility of ameliorating the immunogenicity of mAbs by rigorous exclusion of aggregates from drug product. …”
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腺病毒介导的CD 基因在人胰腺癌细胞中的靶向性表达 by 张世能, 袁世珍

“…【方法】将含癌胚抗原(carcinoembryonic antigen CEA)启动子的重组腺病毒感染人胰腺癌SW1990 细胞(CEA+)、Capan-2 细 胞(CEA-)和人宫颈癌Hela 细胞, 观察CD 基因在3 种细胞中的表达及细胞对5-FC 的敏感性差异。…”
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False Positive B-Cells Crossmatch after Prior Rituximab Exposure of the Kidney Donor by Judith Desoutter, Marie-Joëlle Apithy, Ségolène Bartczak, Nicolas Guillaume

“…An unexpected positive crossmatch may be obtained in recipients with an autoimmune disease or preexisting antibodies not detected by single-antigen bead array due to complement interference or who have been previously treated by desensitization protocols such as rituximab, antithymocyte globulin, or intravenous immunoglobulins. …”
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Immune Privilege as an Intrinsic CNS Property: Astrocytes Protect the CNS against T-Cell-Mediated Neuroinflammation by Ulrike Gimsa, N. Avrion Mitchison, Monika C. Brunner-Weinzierl

“…Depending on the microenvironment, they may become potent antigen-presenting cells for T cells and they may contribute to inflammatory processes. …”
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DEVELOPMENT AND BASIC FEATURES OF INDIRECT ENZYME-LINKED IMMUNOSORBENT ASSAY FOR DETECTION OF ANTIBODIES AGAINST PORCINE EPIDEMIC DIARRHEA by A. V. Kanshina, A. S. Yakovleva, Ye. S. Orlova, A. V. Scherbakov

“…Spread of porcine epidemic diarrhea and its increased threat for the pig industry necessitate development of advanced techniques for the disease diagnosis. Use of recombinant antigens of the disease agent seems prospective. The recombinant antigen-based indirect enzyme-linked immunosorbent assay has been developed for the detection of antibodies against porcine epidemic diarrhea virus. …”
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Paraparesis and paraesthesia following a black ant sting by Norah Alobaid, Majed Alanazi, Sultan Aleshaiwi, Abdulrahman Alhassan

“…Several studies have linked these neurological complications to delayed immunological reactions that are triggered by insect antigen.…”
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Analysis of an HIV infection model incorporating latency age and infection age by Jinliang Wang, Xiu Dong

“…On one hand, activation of latently infected cells needs specificity antigen, and latently infected CD4+ T cells are often heterogeneous, which depends on how frequently they encountered antigens, how much time they need to be preferentially activated and quickly removed from the reservoir. …”
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Approximate smooth solutions of a mathematical model for the activation and clonal expansion of T cells by D. Criaco, M. Dolfin, L. Restuccia

“…In a previous paper a mathematical model was developed for thedynamics of activation and clonal expansion of T cells during theimmune response to a single type of antigen challenge, constructedphenomenologically in the macroscopic framework of a thermodynamictheory of continuum mechanicsfor reacting and proliferatingfluid mixtures. …”
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Dendritic Cells and Their Role in Cardiovascular Diseases: A View on Human Studies by Maja-Theresa Dieterlen, Katja John, Hermann Reichenspurner, Friedrich W. Mohr, Markus J. Barten

“…The antigen-presenting dendritic cells (DCs) are key to the immunological response, with different functions ascribed ranging from cellular immune activation to induction of tolerance. …”
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Clinical Outcomes of Specific Immunotherapy in Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis by Jiang Chen, Guo Xiao-Zhong, Xing-Shun Qi

“…Specific immunotherapies, including vaccines with autologous tumor cells and tumor antigen-specific monoclonal antibodies, are important treatments for PC patients. …”
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Specific receptor usage in Plasmodium falciparum cytoadherence is associated with disease outcome. by Lucy B Ochola, Bethsheba R Siddondo, Harold Ocholla, Siana Nkya, Eva N Kimani, Thomas N Williams, Johnstone O Makale, Anne Liljander, Britta C Urban, Pete C Bull, Tadge Szestak, Kevin Marsh, Alister G Craig

“…This is a complex system involving several host receptors and a major parasite-derived variant antigen (PfEMP1) expressed on the surface of the infected erythrocyte membrane. …”
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The Role of Bacteria and Pattern Recognition Receptors in GvHD by E. Holler, K. Landfried, J. Meier, M. Hausmann, G. Rogler

“…Graft-versus-Host Disease (GvHD) is the most serious complication of allogeneic stem cell transplantation (SCT) and results from an activation of donor lymphocytes by recipient antigen-presenting cells (APCs). For a long time, it has been postulated that the intestinal microflora and endotoxin exert a crucial step in this APC activation, as there is early and severe gastrointestinal damage induced by pretransplant conditioning. …”
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Improving CD3 bispecific antibody therapy in solid tumors using combination strategies by Katy Lloyd, Jim Middelburg, Vitalijs Ovcinnikovs, Nora Pencheva, Kristel Kemper, Thorbald van Hall

“…Furthermore, tumor surface antigen selection for an optimal therapeutic window and acceptable collateral damage to normal tissues is challenging. …”
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Obesity and Cancer Screening according to Race and Gender by Heather Bittner Fagan, Richard Wender, Ronald E. Myers, Nicholas Petrelli

“…In contrast, obese/overweight men reported higher rates of prostate-specific antigen (PSA) testing. Comparison of prostate cancer screening, mammography, and Pap smears implies a gender difference in the relationship between screening behavior and weight. …”
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Role of CEACAM1, ECM, and Mesenchymal Stem Cells in an Orthotopic Model of Human Breast Cancer by Sridhar Samineni, Carlotta Glackin, John E. Shively

“…Carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) is a morphogen in an in vitro model for lumen formation and plays a similar role in breast epithelial cells implanted in humanized mammary fat pads in NOD-SCID mice. …”
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Histopathological and Immunohistochemical Evaluation of African Swine Fever Pigs in Bali Province by Monica Septiani, Vetnizah Juniantito, Bambang Pontjo Priosoeryanto

“…Immunohistochemistry consistently showed p54 viral antigen distribution in mononuclear cells/macrophages across various organs, with the spleen and lymph nodes being dominant sites in 12 pigs (100%). …”
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Genetic Associations in Acquired Immune-Mediated Bone Marrow Failure Syndromes: Insights in Aplastic Anemia and Chronic Idiopathic Neutropenia by Irene Mavroudi, Helen A. Papadaki

“…Various alleles and haplotypes of human leucocyte antigen (HLA) molecules have been implicated in the predisposition of developing the above diseases, as well as polymorphisms of inhibitory cytokines such as interferon-γ, tumor necrosis factor-α, and transforming growth factor-β1 along with polymorphisms on molecules of the immune system including the T-bet transcription factor and signal transducers and activators of transcription. …”
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Belatacept and regulatory T cells in transplantation: synergistic strategies for immune tolerance and graft survival by Gil-Ran Kim, Kyung-Ho Nam, Je-Min Choi

“…Belatacept, a modified version of cytotoxic T lymphocyte antigen-4 immunoglobulin with increased binding affinity for its ligand, has emerged as a viable alternative to traditional CNIs due to its lower toxicity profile. …”
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Adaptive Genetic Traits in Human Populations: Evolutionary Responses to Malaria by Arun Ghosh, Aparna Ajith S, Abhijith Pradeep

“…Notable adaptations include hemoglobinopathies (sickle cell trait, thalassemias, hemoglobin C), enzyme disorders (G6PD deficiency, pyruvate kinase deficiency), and membrane protein variations (Duffy antigen negativity, hereditary ovalocytosis). These traits disrupt the malaria parasite's life cycle or enhance immune responses, thereby protecting against severe disease. …”
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