Extra-ocular sebaceous carcinoma - A rare case report by Manda Sindhura, Tummidi Santosh, Jarang Rajesh Kumar, Arundhathi Shankaralingappa, Naresh Kumar Pannerselvam, Pavithra Balakrishna

“…Immunohistochemistry was positive for epithelial membrane antigen. Sebaceous carcinoma accounts for 0.2–4.6% of all malignant cutaneous neoplasms, and the estimated rate of occurrence is only 1–2 per 1 million individuals per year. …”
Get full text

The Impact of the Myeloid Response to Radiation Therapy by Michael J. Gough, Kristina Young, Marka Crittenden

“…As has been discussed elsewhere, radiation provides debulking, antigen and adjuvant release, and inflammatory targeting of effector cells to the treatment site, thereby assisting multiple critical checkpoints in antitumor adaptive immunity. …”
Get full text

New Concepts in the Diagnosis and Pathogenesis of Trichomonas vaginalis by Renuka Bhatt, Mary Abraham, Dino Petrin, Gary E Garber

“…The application of monoclonal antibodies, either singly or in a group that recognizes a common antigen, along with methods such as detection of common DNA fragment from clinical specimens, may have a promising future in the laboratory diagnosis of trichomoniasis.…”
Get full text

PCNA, Ki-67, p53, bcl-2 and Prognosis in Intraoral Squamous Cell Carcinoma of the Head and Neck by Karin Nylander, Elsy‐Britt Schildt, Mikael Eriksson, Göran Roos

“…PCNA and Ki‐67 labelling showed median values of 56% and 32%, respectively, and neither antigen was of predictive value. Fiftyfive percent of the tumours expressed p53, and 38 (48%) had mutations in the p53 gene. …”
Get full text

A Survey of Artificial Immune System Based Intrusion Detection by Hua Yang, Tao Li, Xinlei Hu, Feng Wang, Yang Zou

“…This framework is analyzed and discussed based on three core aspects: antibody/antigen encoding, generation algorithm, and evolution mode. …”
Get full text

Anti-HPA-1b Mediated Posttransfusion Purpura: A Case Report by O. P. Arewa, S. Nahirniak, G. Clarke

“…PTP is caused by alloimmunization to human platelet specific antigens following blood component transfusion. Although there is evidence of a wide serological spectrum of culprit antibodies implicated, Anti-human-platelet-antigen- (HPA-) 1a is the most common antibody in cases reported. …”
Get full text

Some Basic Aspects of HLA-G Biology by Estibaliz Alegre, Roberta Rizzo, Daria Bortolotti, Sara Fernandez-Landázuri, Enrico Fainardi, Alvaro González

“…Human leukocyte antigen-G (HLA-G) is a low polymorphic nonclassical HLA-I molecule restrictively expressed and with suppressive functions. …”
Get full text

Immunopeptidomics for autoimmunity: unlocking the chamber of immune secrets by Sanya Arshad, Benjamin Cameron, Alok V. Joglekar

“…Abstract T cells mediate pathogenesis of several autoimmune disorders by recognizing self-epitopes presented on Major Histocompatibility Complex (MHC) or Human Leukocyte Antigen (HLA) complex. The majority of autoantigens presented to T cells in various autoimmune disorders are not known, which has impeded autoantigen identification. …”
Get full text

Induction of Immunological Tolerance by Oral Anti-CD3 by Andre Pires da Cunha, Howard L. Weiner

“…Oral tolerance is of unique immunologic importance because it is a continuous natural immunologic event driven by exogenous antigen and is an attractive approach for treatment of these conditions. …”
Get full text

Immunotherapy with CAR-Modified T Cells: Toxicities and Overcoming Strategies by Shangjun Sun, He Hao, Ge Yang, Yi Zhang, Yang Fu

“…T cells modified via chimeric antigen receptors (CARs) have emerged as a promising treatment modality. …”
Get full text

Lamivudine for the Treatment of Membranous Glomerulopathy Secondary to Chronic Hepatitis B Infection by SI Gan, SM Devlin, NW Scott-Douglas, KW Burak

“…A 46-year-old Chinese man had a hepatitis B e antigen seroconversion along with improvement in his nephrotic syndrome after lamivudine therapy. …”
Get full text

The laboratory diagnosis of Chlamydia trachomatis infections by Max A Chernesky

“…Most invasive specimens, such as cervical or urethral swabs, may be collected for culture, antigen or nucleic acid detection. Noninvasive samples such as first-void urine and vaginal swabs can be easily collected by the patient; these samples must be tested by more sensitive nucleic acid amplification tests. …”
Get full text

CD1-Restricted T Cells at the Crossroad of Innate and Adaptive Immunity by Catia S. Pereira, M. Fatima Macedo

“…There are four isoforms of CD1 that are expressed at the surface of antigen presenting cells and therefore capable of presenting lipid antigens: CD1a, CD1b, CD1c, and CD1d. …”
Get full text

Does Hsp60 Provide a Link between Mitochondrial Stress and Inflammation in Diabetes Mellitus? by Joshua Juwono, Ryan D. Martinus

“…We will examine the links between Hsp60 and cellular anti- and proinflammatory processes and specifically address how Hsp60 appears to affect immune inflammation by at least two different mechanisms: as a ligand for innate immune receptors and as an antigen recognised by adaptive immune receptors. We will also look at the role of Hsp60 during immune cell activation in atherosclerosis, a significant risk factor during the pathogenesis of diabetes mellitus.…”
Get full text

Potential Human Models of Infammatory Bowel Disease by Stephen B Hanauer

“…Alternative natural history or interventional studies in patients with human leukocyte antigen (HLA)-B27 spondylarthropathy may be useful. …”
Get full text

The Child as a Surrogate for Diagnosis of Lupus in the Mother by Olufemi O. Adelowo, Kenneth A. Ohagwu, Ejiehi E. Aigbokhan, Richard O. Akintayo

“…The baby was positive for ANA, extractable nuclear antigen (ENA), and anti-Ro/SSA. Pediatric echocardiography was abnormal and electrocardiography confirmed complete heart block.…”
Get full text

(1 →3)- β -D-Glucan and endotoxin modulate immune response to inhaled allergen by R. Rylander, P. G. Holt

“…To study the effects of such a coexposure, the humoral and inflammatory responses were studied in guinea pigs inhaling the T-cell dependent antigen ovalbumin (OVA) and the inflammatory agents (1→3)-β -D-glucan and lipopolysaccharide (LPS). …”
Get full text

Modeling shrimp biomass and viral infection for production of biological countermeasures by H. Thomas Banks, V. A. Bokil, Shuhua Hu, A. K. Dhar, R. A. Bullis, C. L. Browdy, F.C.T. Allnutt

“…Wecouple equations for biomass production with those for vaccine production inshrimp that have been infected with a recombinant viral vector expressing aforeign antigen. The model system entails both size and class-age structure.…”
Get full text

A Chemical Synthesis of Benzo[a]pyrene Hapten and Its Application in a Streptavidin-Horseradish Peroxidase-Based Enzyme-Linked Immunological Analysis by Zhen Ma, Huisheng Zhuang

“…A specific BaP hapten was synthesized and BaP antigens (immunogen, coating antigen) were prepared using diverse methods. …”
Get full text

Investigation of bhv-1, bvdv and eblv infections in bulls selected for artificial investigation of bhv-1, bvdv and eblv infections in bulls selected for artificial by Orhan Yapkıç, Oya Bulut, Atilla Şimşek, Sibel Yavru, Mehmet Kale, OğuzhanAvcı

“…Besides, all seronegative bulls were also detected as antigen negative by ELISA/Ag.…”
Get full text