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821
Regulation of Dendritic Cell Function in Inflammation
Published 2015-01-01“…Dendritic cells (DC) are professional antigen presenting cells and link the innate and adaptive immune system. …”
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822
Coinfection of malaria and scrub typhus in a toddler: First report from South India
Published 2024-01-01“…There was mild leukocytosis with positive C reactive protein. Rapid malarial antigen was positive, and started on antimalarial therapy. …”
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823
Tumor-induced metabolic immunosuppression: Mechanisms and therapeutic targets
Published 2025-01-01“…This review highlights the regulation of antitumor immune responses through metabolic reprogramming in cancer and immune cells and explores therapeutic strategies that target these metabolic pathways in cancer immunotherapy, including using chimeric antigen receptor (CAR)-T cells. We discuss innovative combinations of immunotherapy, cellular therapies, and metabolic interventions that could optimize the efficacy of existing treatment protocols.…”
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824
Progress of Clinical Research on Trop2 in Solid Tumors
Published 2025-01-01“…Trophoblast cell surface antigen 2 (Trop2) is a glycoprotein that is barely expressed in normal tissues but highly expressed in malignant tumors; it is remarkably associated with poor prognosis. …”
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825
In situ Apoptotic and Proliferation Index in Laryngeal Squamous Cell Carcinomas
Published 1998-01-01“…We applied the TUNEL end labelling technique for the investigation of apoptosis and immunohistochemistry (Ki‐67 antigen) for the determination of the cell proliferation.…”
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826
Feline T-Cell Receptor 𝛾 V- and J-Region Sequences Retrieved from the Trace Archive and from Transcriptome Analysis of Cats
Published 2010-01-01“…The variable domains of antigen receptors are very diverse and assembled in a modular system from a number of V-, D-, and J-region genes. …”
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827
Alpha-Fetoprotein and Hepatocellular Carcinoma Immunity
Published 2018-01-01“…Hepatocarcinoma is one of the most prevalent gastroenterological cancers in the world with less effective therapy. As an oncofetal antigen and diagnostic marker for liver cancer, alpha-fetoprotein (AFP) possesses a variety of biological functions. …”
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828
多重等位基因特异性PCR-HLA-ⅡDNA 分型
Published 2000-01-01“…【目的】对人类组织相容性抗原(Human Leucocyte Antigen System)Ⅱ 类进行高分辨基因分析。【方法】用多重PCR 和等位基因特异性PCR 技术相结合[ 1 ,2] , 建立多重等位基因特异性PCR 方法。…”
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829
Dendritic Cell-Based Approaches for Therapeutic Immune Regulation in Solid-Organ Transplantation
Published 2013-01-01“…While mature dendritic cells (DCs) present donor antigen to the immune system, triggering rejection, regulatory DCs interact with regulatory T cells to promote immune tolerance. …”
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830
PSMA Theranostics: Current Status and Future Directions
Published 2018-06-01“…Prostate-specific membrane antigen (PSMA) is a promising target for imaging diagnostics and targeted radionuclide therapy (theranostics) of prostate cancer and its metastases. …”
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831
Plaque Rupture-Induced Myocardial Infarction and Mechanical Circulatory Support in Alpha-Gal Allergy
Published 2020-01-01“…Heparin, being derived from porcine intestinal tissue, may have a degree of cross-reactivity with AG antigen and thus place patients at risk for allergic and even anaphylactic reactions. …”
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832
CAR-T cell therapy: developments, challenges and expanded applications from cancer to autoimmunity
Published 2025-01-01“…Chimeric Antigen Receptor (CAR)-T cell therapy has rapidly emerged as a groundbreaking approach in cancer treatment, particularly for hematologic malignancies. …”
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833
Interpretation of Hormone Levels in Older Patients: Points for Consideration
Published 2012-01-01“…Blood hormone and tumor marker concentrations are usually determined by immunochemical methods which are based on an unique reaction between antigen and assay capture antibody. Despite the speed and simplicity of assays performance on automatic immunochemistry platforms, the interpretation of final results requires a deep knowledge of method fallibility. …”
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834
D8/17 Monoclonal Antibody: An Unclear Neuropsychiatric Marker
Published 2005-01-01“…Objective: It has been hypothesized that monoclonal antibody D8/17 identifies a B lymphocyte antigen with expanded expression in patients with rheumatic fever, childhood onset obsessive-compulsive disorder (OCD), Tourette syndrome (TS) or prepubertal anorexia nervosa (AN). …”
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835
Diagnosis of Cryptococcosis and Prevention of Cryptococcal Meningitis Using a Novel Point-of-Care Lateral Flow Assay
Published 2013-01-01“…Despite access to antiretroviral therapy, mortality from cryptococcal meningitis (CM) is high among persons with advanced HIV infection in sub-Saharan Africa. Cryptococcal antigen (CrAg) is present several weeks to months before the onset of symptoms of meningitis and can be screened to prevent life threatening meningitis. …”
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836
Realization of immune response features by dynamical system models
Published 2007-04-01“…Among the features of real immune responses that occur whenantigens invade a body are two remarkable features.One is that the number of antibodies produced in the secondary invasionby identical antigens is more than 10 times largerthan in the primary invasion.The other is that more effective antibodies, whichare produced by somatic hypermutationduring the immune response,canneutralize the antigens more quickly.This phenomenon is called''affinity maturation''.…”
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837
Using Molecular Markers to Help Predict Who Will Fail after Radical Prostatectomy
Published 2011-01-01“…The standard markers consisting of prostate specific antigen (PSA), Gleason score, and pathological stage are not very specific, so there is an unmet need for other markers to aid in prognostic stratification. …”
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838
Epidemiology and Pathogenesis of Nasal NK/T-Cell Lymphoma: A Mini-Review
Published 2011-01-01“…Further studies including HLA antigen typing of patients is necessary to further clarify the disease mechanism.…”
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839
Markers of metastatic colorectal cancer
Published 2019-05-01“…Current guidelines are based on clinical examination, carcinoembryonic antigen (CEA) testing, computed tomography scanning, and endoscopic surveillance. …”
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840
Retrospective Study Investigating the Prevalence and Clinical Significance of Hepatitis B Virus Precore and Basal Core Promoter Variants
Published 2015-01-01“…BACKGROUND: Hepatitis B virus (HBV) precore (PC) and basal core promoter (BCP) variants are well known; however, their prevalence in North America is unclear, especially among hepatitis B e antigen-negative patients.…”
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