Expression, Purification, and Evaluation of Diagnostic Potential and Immunogenicity of a Recombinant NS3 Protein from All Serotypes of Dengue Virus by Laura Mónica Álvarez-Rodríguez, Angel Ramos-Ligonio, José Luis Rosales-Encina, María Teresa Martínez-Cázares, Aurora Parissi-Crivelli, Aracely López-Monteon

“…The agreement between the NS1 antigen detection versus the rNS3 ELISA, κ=0.837±0.066 (95%  CI = 0.708–0.966), was very good. …”
Get full text

IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy by Dylan Krajewski, Saurav Ranjitkar, Nathan Jordan, Sallie S. Schneider, Clinton B. Mathias

“…However, ST2-/-/IL-10-/- mice exhibited further decreases in OVA-IgE and antigen-specific MC activation compared to ST2-/- mice.ConclusionOur data demonstrates that IL-10 can enhance MC responses in both WT and ST2-/- mice, further corroborating its proinflammatory effects on MCs and suggesting that they are not regulated by IL-33 signaling.…”
Get full text

Serological Survey of Foot-and-Mouth Disease Virus in Buffaloes (Syncerus caffer) in Zambia by T. K. W. Sikombe, A. S. Mweene, John Muma, C. Kasanga, Y. Sinkala, F. Banda, M. Mulumba, E. M. Fana, C. Mundia, M. Simuunza

“…For probang samples, CPE were observed in three of the samples, while the antigen ELISA results showed positivity and for SAT1 (n=1) and SAT2 (n=2). …”
Get full text

Modulation of Tumor Immunity by Soluble and Membrane-Bound Molecules at the Immunological Synapse by Pablo A. González, Leandro J. Carreño, Pablo F. Céspedes, Susan M. Bueno, Claudia A. Riedel, Alexis M. Kalergis

“…A crucial event determining the recognition and elimination of detrimental cells is antigen recognition by the T cell receptor (TCR) expressed on the surface of T cells. …”
Get full text

Enhanced effect of the immunosuppressive soluble HLA-G2 homodimer by site-specific PEGylation by Chisato Yamada, Kimiko Kuroki, Naoyoshi Maeda, Hiroshi Watanabe, Ami Takahashi, Katsumi Maenaka

“…Abstract Human leukocyte antigen (HLA)-G is a nonclassical HLA class I molecule that has an immunosuppressive effect mediated by binding to immune inhibitory leukocyte immunoglobulin-like receptors (LILR) B1 and LILRB2. …”
Get full text

Developing mRNA lipid nanoparticle vaccine effective for cryptococcosis in a murine model by Yeqi Li, Suresh Ambati, Richard B. Meagher, Xiaorong Lin

“…Here, we employed mRNAs encoding an antigen(s) packaged in lipid nanoparticles (LNPs) to develop vaccines for cryptococcosis. …”
Get full text

Dendritic Cells in Tolerance and Immunity against Pathogens by Silvia Beatriz Boscardin, Daniela Santoro Rosa, Alice O. Kamphorst, Christine Trumpfheller

Get full text

OUTBREAK OF SPRING VIRAEMIA OF CARP IN PRIVOLZHSKY FEDERAL DISTRICT IN 2014 by A. A. Pichueva, M. I. Doronin

“…Infectivity titres as well virus antigen concentration in carp pathological material were determined.…”
Get full text

Tuberculosis-Associated Immune Reconstruction Inflammatory Syndrome (TB-IRIS) in HIV-Infected Patients: Report of Two Cases and the Literature Overview by Klaudija Viskovic, Josip Begovac

“…TB-IRIS in HIV-infected subjects is an exacerbation of the symptoms, signs, or radiological manifestations of a pathogenic antigen, related to recovery of the immune system after immunosuppression. …”
Get full text

Disease Burden of Chronic Hepatitis B among Immigrants in Canada by William WL Wong, Gloria Woo, E Jenny Heathcote, Murray Krahn

“…Screening for hepatitis B surface antigen is not recommended for immigrants.…”
Get full text

Examination of pathological process pecularities caused by A/duck/Altai/469/14 H5N1 isolate of avian influenza virus in chickens by V. Yu. Sosipatorova, D. A. Altunin, M. A. Tsivanyuk, I. A. Chvala

“…Data on examination of chickens intranasally infected with А/duck/Altai/469/14 H5N1 isolate of avian influenza virus for clinical signs and microscopic and gross pathomorphological lesions in their organs are given in the paper. The virus antigen was identified in chicken tissue lesions by immunohistochemical method.…”
Get full text

Weal and woe of interleukin-18 in the T cell therapy of cancer by Christoph Kessel, Hinrich Abken, Claudia Rossig

“…Chimeric antigen receptor (CAR) T cell therapy of solid cancer remains below expectations; adding cytokine help through IL-18 has shown remarkable efficacy in first clinical trials. …”
Get full text

Meningothelial Meningioma Component in a Prepubertal Testicular Teratoma by Ruchi Sinha, Madhu Kumari, Ranwir Kumar Sinha, Bindey Kumar

“…Immunohistochemistry was positive for epithelial membrane antigen and vimentin. To our knowledge, this is the first report of meningothelial meningioma in a prepubertal testicular teratoma.…”
Get full text

Disseminated Soft Tissue Infection and Sepsis with Stenotrophomonas maltophilia in a Bone Marrow Transplant Patient by Jeffrey H Lipton, Kelly S MacDonald

“…A 32-year-old female presented with aplastic anemia and subsequently underwent a one-antigen mismatched bone marrow transplant from her brother. …”
Get full text

Current concepts in the pathogenesis of spondyloarthritis by Nibha Jain, Arumugam Moorthy

“…The role of genetics including human leukocyte antigen B27 has been investigated extensively, which along with genome-wide association studies has helped us understand and postulate various theories. …”
Get full text

An overview of ELISA: a review and update on best laboratory practices for quantifying peptides and proteins in biological fluids by Suleyman Aydin, Elif Emre, Kader Ugur, Mustafa Ata Aydin, İbrahim Sahin, Vedat Cinar, Taner Akbulut

“…The enzyme-linked immunosorbent assay (ELISA) detects antigen-antibody interactions by using enzyme-labelled conjugates and enzyme substrates that generate colour changes. …”
Get full text

Laboratory Diagnosis of Chlamydia Pneumoniae Infections by Rosanna W Peeling

“…Culture is highly specific but is technically demanding, expensive, has a long turnaround time and its sensitivity is highly dependent on transport conditions. Antigen detection tests such as enzyme immunoassay and direct fluorescent antibody assay, and molecular detection methods such as the polymerase chain reaction assay, may provide a rapid diagnosis without the requirement for stringent transport conditions. …”
Get full text

Vaccinated, Recovered and Tested in the Workplace: Situation in Firms in Lower Saxony at the End of 2021 by Stephan L. Thomsen, Johannes Trunzer

“…The Employers’ Associations of Lower Saxony (UVN), IHK Hannover, creditreform and the Institute for Economic Policy at Leibniz University Hanover conducted a short online survey on the vaccination and recovery status, the number of antigen rapid tests as well as the proportion of employees working from home. …”
Get full text

Hepatocellular carcinoma in a sheep by Zabid Yener, Hüdaverdi Erer

“…Immunohistochemically. some tumour markers, such as carcinoembryonic antigen (CEA), alpha-letoprotein (AFP), of the intermediate filament proteins, cylokeralin, and superficial antigens of hepatitis B virus was investigated, and alpha-letoprotein (AFP) was founded to be positive.…”
Get full text

The Actin-Bundling Protein L-Plastin: A Critical Regulator of Immune Cell Function by Sharon Celeste Morley

“…While first identified as an abundant cytoplasmic protein in hematopoietically derived cells over 25 years ago, the requirement for L-plastin in multiple functions critical for immunity, such as antigen receptor signaling, adhesion, and motility, has only recently become clear. …”
Get full text