Large-scale manufacturing and characterization of CMV-CD19CAR T cells by Stephen J Forman, Xiuli Wang, Ryan Urak, Miriam Walter, Min Guan, Tianxu Han, Vibhuti Vyas, Sheng-Hsuan Chien, Brenna Gittins, Mary C Clark, Sally Mokhtari, Angelo Cardoso, Don J Diamond, John Zaia, Ryotaro Nakamura

“…Background Adoptive transfer of CD19-specific chimeric antigen receptor (CD19CAR) T cells can induce dramatic disease regression in patients with B cell malignancies. …”
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Dose-dependent serological profiling of AdCLD-CoV19-1 vaccine in adults by Jung Hyuk Lee, Yuna Shin, Kwang-Soo Shin, Ju Yeon Park, Mi Sun Kim, Young-Shin Park, Wuhyun Kim, Joon Young Song, Ji Yun Noh, Hee Jin Cheong, Chang-Yuil Kang, Sang Hwan Seo, Jae-Ouk Kim, Deok Ryun Kim, Nathaniel S. Hwang, Jae Seung Yang, Jerome H. Kim, Byoung-Shik Shim, Manki Song

“…Further analysis using the Omicron BA.2 variant demonstrated that the high-dose group maintained significantly higher levels of IgG and FcγR3B binding to the S2 antigen and exhibited a significantly higher ADNP response for the S2 antigen compared with the low-dose group. …”
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Brucella suis ΔmapB outer membrane vesicles as an acellular vaccine against systemic and mucosal B. suis infection by Florencia Muñoz González, Florencia Muñoz González, Magali G. Bialer, Maria L. Cerutti, Silvia M. Estein, Lila Y. Ramis, Pablo C. Baldi, Pablo C. Baldi, Ángeles Zorreguieta, Ángeles Zorreguieta, Mariana C. Ferrero, Mariana C. Ferrero

“…Intramuscular immunization of mice with both OMVs induced antigen-specific IgG in serum, with the ΔmapB OMVs group showing higher titers compared to the wt OMVs group. …”
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<i>shp-2</i> gene knockout upregulates CAR-driven cytotoxicity of YT NK cells by V. G. Subrakova, S. V. Kulemzin, T. N. Belovezhets, A. N. Chikaev, N. A. Chikaev, O. A. Koval, A. A. Gorchakov, A. V. Taranin

“…These shp-2 knock-out NK cells were additionally transduced to express a chimeric antigen receptor (CAR) that selectively recognized the antigen of interest on the target cell surface and generated an activating signal. …”
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Regulatory T cell-like response to SARS-CoV-2 in Jamaican fruit bats (Artibeus jamaicensis) transduced with human ACE2. by Bradly Burke, Savannah M Rocha, Shijun Zhan, Miles Eckley, Clara Reasoner, Amin Addetia, Juliette Lewis, Anna Fagre, Phillida A Charley, Juergen A Richt, Susan R Weiss, Ronald B Tjalkens, David Veesler, Tawfik Aboellail, Tony Schountz

“…Infection was confined to the intestine for only a few days with prominent viral nucleocapsid antigen in epithelial cells, and mononuclear cells of the lamina propria and Peyer's patches, but with no evidence of infection of other tissues; none of the bats showed visible signs of disease or seroconverted. …”
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The MicroRNA-106a/20b Strongly Enhances the Antitumour Immune Responses of Dendritic Cells Pulsed with Glioma Stem Cells by Targeting STAT3 by Hui Zhou, Chengmei Sun, Cong Li, Shiting Hua, Feng Li, Ruichun Li, Dongpeng Cai, Yuxi Zou, Yingqian Cai, Xiaodan Jiang

“…We cultured GSCs and prepared GSC antigen lysates by apoptosis. Then, immature DCs were pulsed with GSC antigen lysates in vitro. …”
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Kriptokokal meningitis: Aspek klinis dan diagnosis laboratorium by Efrida ., Desi Ekawati

“…Pemeriksaan laboratorium penunjang untuk diagnosis adalah pemeriksaan mikroskopis langsung menggunakan tinta India, deteksi antigen, metode enzyme immunoassay, kultur, dan metode molekular. …”
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Evaluation of the Urine POC-CCA Test Accuracy in the Detection of Schistosoma mansoni Infection: A Systematic Review and Meta-Analysis by Getaneh Alemu, Endalkachew Nibret

“…Overall analysis of Point-of-Care Circulating Cathodic Antigen (POC-CCA) test against KK reference standard revealed a pooled sensitivity and specificity of 0.86 (95% CI: 0.85–0.87) and 0.66 (95% CI: 0.65–0.67), respectively. …”
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Clinical and Hematological Manifestation of Dengue Patients in 2022 Outbreak: A Tertiary Care Hospital‐Based Cross‐Sectional Study by Md. Jubayer Hossain, Manisha Das, Muhibullah Shahjahan, Md. Wahidul Islam, Syeda Tasneem Towhid

“…Laboratory tests showed 63% NS1 antigen (nonspecific antigen 1) positivity, and 16% tested positive for both NS1 and IgM (Immunoglobulin M). …”
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Therapy of genomic unstable solid tumours (WHO grade 3/4）in clinical stage III/IV using individualised neoantigen tumour peptides-INP trial (individualised neoantigen tumour peptid... by Ling Wang, Xia Chen, Juan Zhao, Jiaxi Tang, Wanyan Tang, Bin Liao, Weiqi Nian

“…Through the whole exome and transcriptome sequencing analysis of the fresh blood and tumour tissues of the enrolled patients, the 20 25-33aa antigen peptides with the highest mutation scores of the patients will be screened out, and the corresponding new antigen peptides will be synthesised and prepared. …”
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Comparative monocyte and T cell responses in DENV-exposed subjects from South-East Asia and DENV-naïve residents in Taiwan by Sheng-Hsuan Wang, Yun-Erh Chuang, Sia-Seng Tan, Tzu-Chuan Ho, Oscar Guey Chuen Perng, Po-Lin Chen

“…In addition, it was observed that the function of T cells was also equivalent when monocytes were present as antigen-presenting cells for dengue antigen, NS3, in terms of cell proliferation, interferon-gamma (IFNγ) secretion, and memory response. …”
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High Dimensionality Reduction and Immune Phenotyping of Natural Killer and Invariant Natural Killer Cells in Latent Tuberculosis-Diabetes Comorbidity by Gokul Raj Kathamuthu, Nathella Pavan Kumar, Kadar Moideen, Pradeep A. Menon, Subash Babu

“…Finally, NK and iNKT cell frequencies did not exhibit significant differences upon positive control antigen stimulation between the study population. …”
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Primary Lymphoma of the Liver: A Case Report and Review by Franzjosef Schweiger, Rowen Shinder, Sheldon Rubin

“…The diagnosis of these rare tumours is suggested by the presence of a hepatic mass without lymphadenopathy, splenomegaly or bone marrow involvement, as well as normal carcinoembryonic antigen and alpha-fetoprotein levels. However, histological examination of tissue is essential to confirm the diagnosis. …”
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Atypical Dengue Outbreak in Odisha: Insights from the Entomological Investigations by Sudhansu Sekhar Sahu, Mohammed Mustafa Baig, Dilip Kumar Panigrahi, Ananganallur Nagarajan Shriram, Ashwani Kumar

“…Among 117 fever cases, 49 tested positive for the dengue NS1 antigen. To identify mosquito-related factors in the outbreak, a survey of 101 houses found Aedes breeding sites in 11.6% of containers. …”
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Immunotherapeutic Strategies for Alzheimer's Disease Treatment by Beka Solomon

“…Immunotherapy represents fascinating ways to test the amyloid hypothesis and offers genuine opportunities for AD treatment, but requires careful antigen and antibody selection to maximize efficacy and minimize adverse events.…”
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Spondyloarthritis associated with inflammatory myositis: An unusual case report by Pradip Kumar Prajapati

“…Her radiological studies showed sacroiliitis with inflammatory edema in the thigh muscle, with laboratory investigations showing elevated levels of creatine phosphokinase and inflammatory markers and positive human leukocyte antigen B27. She responded well to treatment (prednisolone, methotrexate, analgesic, and supportive medicines) with normalization of laboratory parameters and improved clinically.…”
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Diagnosis of Respiratory Tract Infection and the Use of the Laboratory by Ronald F Grossman

“…Blood cultures should be drawn in patients ill enough to require hospitalization, but the yield is low, Pneumococcal antigen testing and serological studies do not add to the routine management of patients with pneumonia. …”
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Increased apoptosis of peripheral blood mononuclear cells in patients with perennial allergic asthma/rhinitis: relation to serum markers of apoptosis by Janina Grzegorczyk, Marek L. Kowalski, Anna Pilat, Jolanta Iwaszkiewicz

“…Background: The goal of our study was to examine spontaneous and stimulated apoptosis of peripheral blood MNC from allergic patients, sensitized to Der p I antigen as compared to cells from non-atopic subjects. …”
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A Rare Case of Acute Pancreatitis as Dengue Complication by Tuy Hong Thi Nguyen, Hien Quang Nguyen

“…Dengue virus nonstructural protein 1 (NS1) antigen was positive. Laboratory tests were significant for thrombocytopenia of 67.000/mm3 and high hematocrit of 45%. …”
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Disseminated Histoplasmosis with Underlying Sarcoidosis-Rheumatoid Arthritis Overlap Syndrome: An Example of Diagnostic Test Threshold of Detection Affecting Test Results and Patie... by Daniel Pankratz, Jordan Tichenor, Fernando Merino, Nathan C. Bahr

“…We describe a patient on azathioprine and rituximab with disseminated histoplasmosis in which diagnosis was delayed in part because of negative early Histoplasma antigen testing, which was positive later in the course. …”
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