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581
Developing an On‐Resin Synthesis of α‐Galactosylceramide‐Peptide Conjugate Vaccines
Published 2025-01-01“…In vivo testing showed that vaccines incorporating peptide antigen attached via the galactosyl head group induced strong antigen specific CD8+ T cell responses compared to those with antigen attached via the lipid tail and control vaccine manufactured in a stepwise manner.…”
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582
Selective inhibition by antiflamrnin-2 of thromboxane B2 release from isolated and perfused guinea-pig lung
Published 1992-01-01“…AF-2 (10–100 nM) inhibited leukotriene C4- (LTC4) (3 ng) and antigen-induced (ovalbumin, 1 mg) TXB2 release in normal and sensitized lungs, respectively. …”
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583
Third-Generation Anti-CD47-Specific CAR-T Cells Effectively Kill Cancer Cells and Reduce the Genes Expression in Lung Cancer Cell Metastasis
Published 2021-01-01“…CD47 is an important tumor antigen for the development and progression of various cancers. …”
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584
Identification of T and В lymphocytes in chickens and their subpopulations byflowcytofluorometric analysis using flow cytometer BD FACSVerse™
Published 2018-04-01“…Method of lymphocytic gate extraction with control of leukocyte common antigen CD45 and monocytic antigen expression was determined. …”
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585
Structural analysis of light chain-driven bispecific antibodies targeting CD47 and PD-L1
Published 2024-12-01“…In contrast to natural antibodies that rely mainly on the heavy chain to establish contacts with their cognate antigen, we have developed a bispecific antibody format in which the light chain (LC) drives antigen binding and specificity. …”
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586
Differential Regulation of DC Function, Adaptive Immunity, and MyD88 Dependence by Two Squalene Emulsion-Based Vaccine Adjuvants
Published 2024-05-01“…We found AddaVax more potently enhanced antigen uptake at the local injection site, while AddaS03 more potently enhanced antigen uptake in the draining lymph nodes. …”
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587
Desensitization of delayed-type hypersensitivity in mice: suppressive environment
Published 1993-01-01“…The systemic injection of high doses of antigen into a preimmunized animal results in transient unresponsiveness of cell-mediated immune responses. …”
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588
A PAF receptor antagonist inhibits acute airway inflammation and late-phase responses but not chronic airway inflammation and hyperresponsiveness in a primate model of asthma
Published 1992-01-01“…A single oral administration WEB 2170 provided dose related inhibition of the release of leukotriene C4 (LTC4) and prostaglandin D2 (PGD2) recovered and quantified in bronchoalveolar lavage (BAL) fluid obtained during the acute phase response to inhaled antigen. In addition, oral WEB 2170 treatment in dual responder primates blocked the acute influx of neutrophils into the airways as well as the associated late-phase airway obstruction occurring 6 h after antigen inhalation. …”
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589
An Overview of the Molecular Methods in the Diagnosis of Gastrointestinal Infectious Diseases
Published 2020-01-01“…Conventional diagnosis of these infections is performed by culture, microscopy, and antigen detection immunoassays. The traditional culture and microscopy procedures are time-consuming, lack sensitivity, and require special laboratory setup and well-trained staff. …”
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590
Two Cases of Miliary Tuberculosis and Increasing Level of CA-125
Published 2006-01-01“…Two cases of miliary tuberculosis and elevated levels of cancer antigen 125 Ovarian carcinoma is one of the most dangerous malignancies in women. …”
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591
Reinforcing cancer immunotherapy with engineered porous hollow mycobacterium tuberculosis loaded with tumor neoantigens
Published 2025-02-01“…Background Enhancing antigen cross-presentation is essential for the development of a tumor neoantigen vaccine. …”
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592
Roitt's essential immunology /
Published 2017Table of Contents: “…Innate immunity -- Specific acquired immunity -- Antibodies -- Membrane receptors for antigen -- Antigen-specific recognition -- Immunological methods and applications [JS2] -- The anatomy of the immune response -- Lymphocyte activation -- The production of effectors -- The regulation of the immune response -- Development and evolution of the immune response -- Adversarial strategies during infection -- Vaccines -- Immunodeficiency -- Allergy and other hypersensitivities -- Transplantation -- Tumor immunology -- Autoimmune diseases.…”
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593
DEL phenotype in RhD-negative North Indian blood donors
Published 2024-01-01“…The extended Rh phenotype performed for these donors showed that 6.83% (n = 14) donors were positive for RhC antigen and 1.46% (n = 3) were positive for Rh E antigen. …”
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594
Autoantibody with Cross-Reactivity between Insulin and Ductal Cells May Cause Diabetic Mastopathy: A Case Study
Published 2012-01-01“…These anti-insulin antibodies produced in the DM patient may cause ductitis because of antigen cross-reactivity.…”
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595
Vaccines for cancer interception in familial adenomatous polyposis
Published 2025-01-01“…Appropriately primed antigen specific T-cells can traffic to any site in the body where antigen is expressed, recognize, and eliminate the antigen expressing cell. …”
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596
Occurrence of Bordetella Infection in Pigs in Northern India
Published 2014-01-01“…Of the pig sera tested with MAT and ELISA for Bordetella antibodies, 67.6% and 86.3% samples, respectively, were positive. For antigen detection mPCR was more sensitive than conventional bacterioscopy while for detection of antibodies neither of the two tests (MAT and ELISA) had specificity in relation to antigen detection. …”
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597
Problems and prospects of bovine tuberculosis serological diagnosis
Published 2021-03-01“…Complement fixing and haemagglutinating antibodies were found to be active in tuberculin anergic animals. A higher antigenicity of Ukrainian RIEVM TB antigen complex as compared to Siberian RVI one was revealed by complement fixation test as well as by indirect haemagglutination test using VIEV polysaccharide antigen; the detection rate was 68 (7.0%), 28 (2.9%) and 299 (30.6%) respectively. …”
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598
Ethanol Extract of Sesamum indicum Linn. Inhibits FcεRI-Mediated Allergic Reaction via Regulation of Lyn/Syk and Fyn Signaling Pathways in Rat Basophilic Leukemic RBL-2H3 Mast Cell...
Published 2019-01-01“…SIE inhibited the degranulation and secretion of inflammatory mediators in antigen/IgE-sensitized mast cells. SIE reduced the expressions of FcεRI signaling-related genes, such as Syk, Lyn, and Fyn, and the phosphorylation of extracellular signal-regulated kinase in antigen/IgE-sensitized mast cells. …”
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599
Comprehensive review of pollen-food allergy syndrome: Pathogenesis, epidemiology, and treatment approaches
Published 2025-01-01“…In PFAS pathogenesis, when food containing protein antigens (pan-allergens) with high homology to pollen antigens is ingested, mast cells bound to pollen antigen-specific IgE distributed in the oral mucosa cross-react with the food antigen, causing a local type I allergic reaction. …”
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600
Lack of Disease Specificity Limits the Usefulness of In Vitro Costimulation in HIV- and HCV-Infected Patients
Published 2008-01-01“…Measurements of antigen-specific T cell responses in chronic diseases are limited by low frequencies of antigen-specific cells in the peripheral blood. …”
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