Rh and Kell phenotyping in voluntary blood donors: A study from a tertiary care blood center of western India by Sangita D. Shah, Nidhi M. Bhatnagar, Mamta C. Shah, Garima H. Thakkar, Ujjwal Ahuja, Anu Patel, Drashti Gajera, Priya G. Kalavadiya

“…The Rh blood group system has 56 antigens, out of them 5 antigens D, C, c, E, and e are clinically significant antigens. …”
Get full text

Prevalence of Cryptococcal Antigenemia and Associated Factors among HIV/AIDS Patients at Felege-Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia by Mohabaw Jemal, Teshiwal Deress, Teshome Belachew, Yesuf Adem

“…Cryptococcal antigen was detected from serum by using Remel Cryptococcal Antigen Test Kit. …”
Get full text

The role of microbial enzymes β-glucanase and α-amylase in optimising feed production for poultry by Zhanar Narmuratova, Raushan Blieva, Zhanara Suleimenova, Nurlan Akhmetsadykov, Gulbakhyt Zhumagalieva

Get full text

Serological and virological investigation of bovine viral diarrhea virus infection in cattle with abortion problem by Oya Bulut, Oguzhan Avci, Orhan Yapici, Orhan, Sibel Yavru, Atilla Simsek

“…<p> <b>Results:</b> In this research, 41 (17.9%) sera were found seropositive and 4 (1.7%) leukocytes were BVDV antigen positive. Of these 4 BVDV antigen positive cattle, a number of 2 (0.8%) were detected seropositive while 2 (0.8%) were seronegative. …”
Get full text

DEVELOPMENT AND USE OF THE COMPETITIVE ELISA-BASED TEST SYSTEM FOR DETECTION OF ANTIBODIES TO GROUP A ROTAVIRUS IN LIVESTOCK SERA by O. P. Bjadovskaya, Ye. A. Bukhon, A. A. Nesterov

“…It is group-specific and the most technologically suitable for production antigen scaling-up. Specificity of prepared components, rotavirus antigen and hyperimmune rabbit serum, was confirmed by real-time PCR and immunoblotting. …”
Get full text

Persistence of Diarrheal Pathogens Is Associated with Continued Recruitment of Plasmablasts in the Circulation by Anu Kantele

“…Intestinal antigen encounter leads to recirculation of antigen-specific plasmablasts via lymphatics and blood back to the intestine. …”
Get full text

Diagnostic Challenges of Helicobacter pylori Infection in Ethiopia: A Community-Based Cross-Sectional Study by Esayas Kebede Gudina, Hiwot Amare, Solomon Ali, Melkamu Berhane Arefayine, Dagmawi Tewolde, Million Tesfaye Eshete, Mulusew Gerbaba Jebena, Andreas Wieser, Guenter Froeschl, Markos Tesfaye, Hailemichael Desalegn, Mulatu Gashaw

“…This study aimed to assess the clinical utility of locally available serological and stool antigen test kits in the management of people with suspected H. pylori infection in Ethiopia. …”
Get full text

Underappreciated layers of antibody-mediated immune synapse architecture and dynamics by Benjamin S. Goldberg, Margaret E. Ackerman

“…These activities are canonically understood to be both modular: antigen recognition is driven by the heterodimeric antigen-binding fragment, and innate immune recruitment by the homodimeric constant/crystallizable fragment. …”
Get full text

Severe atopic dermatitis treated with Dupilumab in a CTLA-4-deficient patient: A case report and review of the literature by Ye-Jean Park, Jennifer Grossman, Lynne Robertson

“…Cytotoxic T lymphocyte-associated antigen 4 deficiency, a primary immune disorder, can exacerbate atopic dermatitis. …”
Get full text

X-Linked Lymphoproliferative Syndrome and Common Variable Immunodeficiency May Not Be Differentiated by SH2D1A and XIAP/BIRC4 Genes Sequence Analysis by Nesrin Gulez, Guzide Aksu, Afig Berdeli, Neslihan Karaca, Sema Tanrıverdi, Necil Kutukculer, Elif Azarsiz

“…A six-year-old male patient was admitted with the complaints of persistent general lymphadenopathy, for two years had fever, bilateral cervical multiple microlymphadenopathy, hepatic/splenic enlargement with laboratory findings as decreased serum immunoglobulins, negative EBV VCA IgM (viral capsid antigen) and anti-EBV EA (antibody to early D antigen), positive EBV VCA IgG (viral capsid antigen) and EBV EBNA (antibody to nuclear antigen). …”
Get full text

Computational epitope-based vaccine design with bioinformatics approach; a review by Esmaeil Roohparvar Basmenj, Susan Radman Pajhouh, Afsane Ebrahimi Fallah, Rafe naijian, Elmira Rahimi, Hossein Atighy, Shadan Ghiabi, Shamim Ghiabi

“…Once the optimal antigen is identified, the next step involves uncovering epitopes within this antigen. …”
Get full text

Application of serological methods combined with flow cytometry in the detection of immune hemolytic transfusion reaction by LIU Lei, ZENG Qunjuan, GONG Guoqin, XIANG Dong, WANG Zhongying

“…After separation using capillary centrifugation technology, both the proximal and distal DAT and Jka antigen tests were negative. Both DAT and Jka antigen positive red blood cells (0.21%, 6/6 327) were found in the patient's blood samples by flow cytometry. …”
Get full text

Do antibody CDR loops change conformation upon binding? by Chu’nan Liu, Lilian M. Denzler, Oliver E.C. Hood, Andrew C.R. Martin

“…During development, it is often necessary to increase or reduce the affinity of an antibody and rational attempts to do so rely on having a structure of the antibody-antigen complex often obtained by modeling. The antigen-binding site consists primarily of six loops known as complementarity-determining regions (CDRs), and an open question has been whether these loops change their conformation when they bind to an antigen. …”
Get full text

Differential Immune Response against Recombinant Leishmania donovani Peroxidoxin 1 and Peroxidoxin 2 Proteins in BALB/c Mice by Nada S. Daifalla, Abebe Genetu Bayih, Lashitew Gedamu

“…Furthermore, the presence of TLR agonists together with rLdPxn1 antigen enhanced the production of IFN-γ and to a lesser extent of IL-10. …”
Get full text

WEAKLY POSITIVE RH FACTOR, DIAGNOSED FOR THE FIRST TIME IN A WOMAN DURING PREGNANCY (CLINICAL CASE) by Юлия Сергеевна Фролова, Екатерина Владимировна Грищенко, Светлана Ивановна Елгина, Елена Владимировна Рудаева, Кира Борисовна Мозес

“…The weakly positive Rh factor (Du phenotype) was described by physician and researcher Frederick Stratton in 1946 as a new variant of the antigen that reacts weakly with anti-D identifying sera. …”
Get full text

Nanobody engineering: computational modelling and design for biomedical and therapeutic applications by Nehad S. El Salamouni, Jordan H. Cater, Lisanne M. Spenkelink, Haibo Yu

“…We explore their unique antigen‐binding domains, highlighting the critical role of complementarity‐determining regions in target recognition and specificity. …”
Get full text

Mechanisms of allorecognition and xenorecognition in transplantation by Il Hee Yun, Jaeseok Yang

“…Foreign antigen recognition is the ability of immune cells to distinguish self from nonself, which is crucial for immune responses in both invertebrates and vertebrates. …”
Get full text

Passive Protection of Diabetic Rats with Antisera Specific for the Polysaccharide Portion of the Lipopolysaccharide Isolated from Pseudomonas pseudomallei by Larry E Bryan, Sallene Wong, Don E Woods, David AB Dance, W Chaowagul

“…The wide distribution of the polysaccharide antigen among isolates of P pseudomallei used in this study and the protective role of antibody to the conjugated polysaccharide antigen suggest potential as a vaccine.…”
Get full text

Ode to Oseltamivir and Amantadine? by JM Conly, BL Johnston

“…The N antigen contains subtype-specific antigens and also demonstrates antigenic variation between subtypes. …”
Get full text

Antibody in Lymphocyte Supernatant (ALS) responses after oral vaccination with live Shigella sonnei vaccine candidates WRSs2 and WRSs3 and correlation with serum antibodies, ASCs,... by Malabi M Venkatesan, Cassandra Ballou, Shoshana Barnoy, Monica McNeal, Jill El-Khorazaty, Robert Frenck, Shahida Baqar

“…The levels of antigen-specific Antibodies in Lymphocyte Supernatant (ALS) using an ELISA are being used to evaluate mucosal immune responses as an alternate to measuring the number of Antibody Secreting Cells (ASCs) using an ELISpot assay. …”
Get full text