Non-small cell lung cancer and the tumor microenvironment: making headway from targeted therapies to advanced immunotherapy by Anna De Lucia, Lucia Mazzotti, Lucia Mazzotti, Anna Gaimari, Anna Gaimari, Matteo Zurlo, Roberta Maltoni, Claudio Cerchione, Sara Bravaccini, Angelo Delmonte, Lucio Crinò, Patricia Borges de Souza, Luigi Pasini, Fabio Nicolini, Fabrizio Bianchi, Manel Juan, Hugo Calderon, Chiara Magnoni, Chiara Magnoni, Luca Gazzola, Luca Gazzola, Paola Ulivi, Massimiliano Mazza

Subjects: Get full text

Linear IgA bullous dermatosis–a fifty year experience of Warsaw Center of bullous diseases by Cezary Kowalewski, Katarzyna Wozniak

Subjects: Get full text

Enzyme-linked immunosorbent assay for post-slaughter diagnosis of bovine leukosis by A. R. Mustafayev, M. O. Baratov

Subjects: Get full text

Designing multi-epitope vaccines against Echinococcus granulosus: an in-silico study using immuno-informatics by Jadoon Khan, Asma Sadiq, May M. Alrashed, Nosheen Basharat, Syed Nadeem Ul Hassan Mohani, Tawaf Ali Shah, Kotb A. Attia, Aamer Ali Shah, Hayat Khan, Ijaz Ali, Arif Ahmed Mohammed

Subjects: “…Echinococcus granulosus Antigen B (EgAgB)…”
Get full text

iPSC Technology Revolutionizes CAR-T Cell Therapy for Cancer Treatment by Jiepu Zong, Yan-Ruide Li

Subjects: Get full text

C-Tb Skin Test: A Step Toward Tuberculosis Eradication by Harshini T Reddy, Bhaskar Shenoy

Subjects: Get full text

A simple, highly sensitive and specific serological test for the detection of antibodies to Varicella-zoster virus (<i>Varicellovirus humanalpha3</i>) by Firaya G. Nagieva, Elena P. Barkova, Olga S. Kharchenko, Alexander V. Sidorov, Galina I. Alatortseva, Bogdan S. Cherepovich, Yulia N. Tarakanova, Olga A. Trubacheva, Evgeny A. Pashkov, Artem A. Rtishchev, Oksana A. Svitich, Vitaly V. Zverev

Subjects: Get full text

Differential expression of CD175 and CA19-9 in pancreatic adenocarcinoma by Jane J. Cheng, Yasuyuki Matsumoto, Gabrielle E. Dombek, Kathryn A. Stackhouse, Ana Sofia Ore, Jonathan N. Glickman, Jamie Heimburg-Molinaro, Richard D. Cummings

Subjects: “…Tumor-associated carbohydrate antigens (TACAs)…”
Get full text

Mechanisms behind Functional Avidity Maturation in T Cells by Marina Rode von Essen, Martin Kongsbak, Carsten Geisler

“…During an immune response antigen-primed B-cells increase their antigen responsiveness by affinity maturation mediated by somatic hypermutation of the genes encoding the antigen-specific B-cell receptor (BCR) and by selection of higher-affinity B cell clones. …”
Get full text

Baseline Antibody Titre against Salmonella enterica in Healthy Population of Mumbai, Maharashtra, India by Rucha Patki, Sunil Lilani, Dhaneshwar Lanjewar

“…Paratyphi AH antigen.…”
Get full text

Antibody Response in Seropositive Multiple Sclerosis Patients Vaccinated with Attenuated Live Varicella Zoster Virus by RT Ross, MR Dawood, Mary Cheang, Lindsay E Nicolle

“…OBJECTIVE: To determine the safety and effectiveness of live attenuated varicella zoster virus (VZV) vaccine (OKA/Merck) on 50 patients with chronic progressive multiple sclerosis (MS), based on the hypothesis that VZV might be the antigen or antigen mimic of MS plus the fact that repeated high antigen doses have produced ‘antigen paralysis’ in experimental allergic encephalomyelitis mice.…”
Get full text

Technologies of suspension cultivation in bioreactor of the Chlamydophila abortus strain on McCoy cell culture by Yerkin Krykbayev, Nurtas Tyrsynbayev, Nurlan Akhmetsadykov, Damir Khussainov, Zhanat Batanova

“…Complement fixation tests with chlamydia antigen were found to be positive in 7 (23%) of the 30 animals that were examined. …”
Get full text

Dendritic Cells and Their Multiple Roles during Malaria Infection by Kelly N. S. Amorim, Daniele C. G. Chagas, Fernando B. Sulczewski, Silvia B. Boscardin

“…Dendritic cells (DCs) play a central role in the initiation of adaptive immune responses, efficiently presenting antigens to T cells. This ability relies on the presence of numerous surface and intracellular receptors capable of sensing microbial components as well as inflammation and on a very efficient machinery for antigen presentation. …”
Get full text

FREQUENCY OF RH-D NEGATIVE & WEAK D IN PAKISTANI POPULATION by Muhammad Usman et al

“…The expression of its antigens is complex, among that Rh-D antigen is the most important antigen because of its high immunogenicity. …”
Get full text

Innovative immunotherapies and emerging treatments in type 1 diabetes management by Malek Zarei, Mohammad Abbas Sheikholeslami, Masoud Mozaffari, Yassar Mortada

“…This review comprehensively examines the latest advances in immunotherapeutic approaches to T1D, categorizing current strategies into four main groups: antigen-independent therapies, antigen-dependent therapies, beta cell therapies, and stem cell therapies. …”
Get full text

Trogocytosis-mediated immune evasion in the tumor microenvironment by Jeonghyun Kim, Soyeon Park, Jungseo Kim, Yewon Kim, Hong Min Yoon, Bima Rexa Rayhan, Jaekwang Jeong, Alfred L. M. Bothwell, Jae Hun Shin

“…For example, CD4 T cells engaging with antigen-presenting cells undergo trogocytosis, which facilitates the transfer of antigen-loaded major histocompatibility complex (MHC) class II molecules from antigen-presenting cells to CD4 T cells. …”
Get full text

Pre-transfusion detection and transfusion therapy of a patient with autoanti-B and cold agglutinin by YANG Linyu, CHEN LI, LI Zhongjun

“…[Objective] To identify the ABO blood group of a patient with rare B antigen-specific autoantibody with cold agglutinin, and evaluate the effect of blood transfusion. …”
Get full text

Dual-targeting CAR T cells for B-cell acute lymphoblastic leukemia and B-cell non-Hodgkin lymphoma by Gustavo de Oliveira Canedo, Claire Roddie, Persis J. Amrolia

“…CAR T-cell persistence remains a significant issue, with the majority of relapses being antigen-positive after CAR T-cell infusion. Further, despite adding a second antigen, antigen-negative relapses have not yet been eliminated. …”
Get full text

Sequence-based engineering of pH-sensitive antibodies for tumor targeting or endosomal recycling applications by Wanlei Wei, Traian Sulea

“…Inexpensive computational techniques to predict the effectiveness of His pH-switches require antibody-antigen complex structures, but these are lacking in most cases. …”
Get full text

IL-6-mediated MHC class II induction on RIN-5AH insulinoma cells by IFN-γ occurs via the G-protein pathway by S. Vassiliadis, G. K. Papadopoulos

“…Major histocompatibility complex (MHC) class II antigen expression has been implicated in the pathogenesis of autoimmune type 1 diabetes. …”
Get full text