Suggested Topics within your search.
Showing 501 - 520 results of 1,973 for search '"antigen"', query time: 0.08s Refine Results
  1. 501

    Current Challenges in Prostate Cancer Management and the Rationale behind Targeted Focal Therapy by Al B. Barqawi, Kevin J. Krughoff, Khadijah Eid

    Published 2012-01-01
    “…In this effort, a review of major epidemiological and screening studies, cancer statistics from the advent of prostate-specific antigen screening to the present, and reports on patient concerns and treatment outcomes was conducted to present the dominant factors that underlie current challenges in prostate cancer treatment and illuminate potential solutions.…”
    Get full text
    Article
  2. 502

    Analysis of the IFN-γ-induced signal transduction pathway in fetal rejection by Irene Athanassakis

    Published 1995-01-01
    “…In this work the in vitro and in vivo signal transduction pathways followed by IFN-γ or 5-azaC to induce class H antigen expression on placental cells by using specific pathway inhibitors has been studied. …”
    Get full text
    Article
  3. 503

    The Pathophysiological Impact of HLA Class Ia and HLA-G Expression and Regulatory T Cells in Malignant Melanoma: A Review by Lasse Lindholm Johansen, Jørgen Lock-Andersen, Thomas Vauvert F. Hviid

    Published 2016-01-01
    “…The examination of the interaction between the human leucocyte antigen (HLA) system and prognostic outcome has shown interesting results, and a correlation between the down- or upregulation of these antigens and prognosis has been seen through many different types of cancer. …”
    Get full text
    Article
  4. 504

    Colitis in spondyloarthritis by Muhammed Hafis, Vikas Agarwal

    Published 2020-01-01
    “…Apart from the strong Class I human leukocyte antigen B27 link for both diseases, several new shared genetic risk loci are identified from genome-wide association studies. …”
    Get full text
    Article
  5. 505

    The Role of Dendritic Cells in Adaptive Immune Response Induced by OVA/PDDA Nanoparticles by Daniele R. Pereira, Yunys Pérez-Betancourt, Bianca C. L. F. Távora, Geraldo S. Magalhães, Ana Maria Carmona-Ribeiro, Eliana L. Faquim-Mauro

    Published 2025-01-01
    “…Dendritic cells (DCs), as sentinels of foreign antigens, exert a crucial role in the antigen-specific immune response. …”
    Get full text
    Article
  6. 506

    Isolation of PCSK9-specific nanobodies from synthetic libraries using a combined protein selection strategy by Apisitt Thaiprayoon, Yodpong Chantarasorn, Worrapoj Oonanant, Anongnard Kasorn, Phoomintara Longsompurana, Satita Tapaneeyakorn, Pinpunya Riangrungroj, Fabien Loison, Andrew C. Kruse, Matthew P. DeLisa, Dujduan Waraho-Zhmayev

    Published 2025-01-01
    “…We have developed a reliable protein selection strategy that combines magnetic activated cell sorting (MACS)-based screening of yeast surface display (YSD) libraries and functional ligand-binding identification by Tat-based recognition of associating proteins (FLI-TRAP) to isolate antigen-specific Nbs from synthetic libraries. This combined process enabled isolation of three unique Nb clones (NbT15, NbT21, and NbT22) that all bound specifically to a target antigen, namely proprotein convertase subtilisin/kexin type 9 (PCSK9) as well as a gain-of-function PCSK9 mutant (D374Y). …”
    Get full text
    Article
  7. 507

    A cell-penetrating bispecific antibody suppresses hepatitis B virus replication and secretion by Chongwei Xie, Bing Zhou, Da Yao, Xin Wang, Lihong Zhong, Chuanghua Qiu, Junfang Zhang

    Published 2025-03-01
    “…The antibody could recognize preS1 and HBcAg and internalize into living cells efficiently, suppressing the extracellular hepatitis B surface antigen (HBsAg) and hepatitis B envelope antigen, and the intracellular HBsAg and HBcAg in vitro. …”
    Get full text
    Article
  8. 508

    Identification of HPV16 E1 and E2-specific T cells in the oropharyngeal cancer tumor microenvironment by Christine McInnis, Lakshmi Srinivasan, Anthony J Coyle, Shilpa Bhatia, Glenn J Hanna, Ann Marie Egloff, Brinda Vijaykumar, Qiaomu Tian, Yanbo Sun, Del Leistritz-Edwards, Charles T Quinn, Ravi Uppaluri, Daniel C Pregibon

    Published 2023-03-01
    “…The viral etiology of these cancers provides the opportunity for antigen-directed therapies that are restricted in scope compared with cancers without viral components. …”
    Get full text
    Article
  9. 509
  10. 510
  11. 511

    Analysis of Signals Leading to Differentiation of Immature HL-60 after Administration of IL-4 by Simon Vassiliadis

    Published 1994-01-01
    “…For instance, induction of HLA-DR antigens on human promyelocytic leukaemia HL-60 cells by interleukin-4 (IL-4) is of pivotal importance in immunology not only because class II expression is prerequisite to antigen recognition and response but also because IL-4 participates in a plethora of inflammatory or non-inflammatory reactions. …”
    Get full text
    Article
  12. 512

    Recent Advances in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms by Hideaki Watanabe

    Published 2018-01-01
    “…Recently, the pathogenic mechanism of T-cell activation triggered by human leukocyte antigen- (HLA-) restricted presentation of a drug or metabolites was elucidated. …”
    Get full text
    Article
  13. 513

    Treatment of end-stages of liver disease in outcome of persistent hepatitis C virus infection at deficiency of donor organs by Ye. N. German, M. V. Mayevskaya, O. I. Andreytseva, V. T. Ivashkin, A. V. Chzhao, A. G. Serova, G. V. Mikhaylovskaya, I. Yu. Pirogova

    Published 2011-03-01
    “…To study the role of serological markers of hepatitis B virus infection: antibodies to hepatitis B virus cor-antigen (anti-HВcor IgG) in progressing liver damage at patients with persistent hepatitis C virus infection.Material and methods. …”
    Get full text
    Article
  14. 514

    Immunotherapy Deriving from CAR-T Cell Treatment in Autoimmune Diseases by Yuehong Chen, Jianhong Sun, Huan Liu, Geng Yin, Qibing Xie

    Published 2019-01-01
    “…Chimeric antigen receptor T (CAR-T) cells are T cells engineered to express specific synthetic antigen receptors that can recognize antigens expressed by tumor cells, which after the binding of these antigens to the receptors are eliminated, and have been adopted to treat several kinds of malignancies. …”
    Get full text
    Article
  15. 515

    Perianal Basal Cell Carcinoma Successfully Managed with Excisional Biopsy by Paola C. Aldana, Harris G. Yfantis, Preeti R. John

    Published 2019-01-01
    “…Immunohistochemical staining confirmed the diagnosis: it showed diffuse and strong positivity for smooth muscle actin (SMA) and monoclonal antibody BER-Ep4 and was negative for carcinoembryonic antigen (CEA), pancytokeratin (AE1/AE3), and epithelial membrane antigen (EMA). …”
    Get full text
    Article
  16. 516

    T-regulatory cells for the treatment of autoimmune diseases by Marina S. Fisher, Marina S. Fisher, Sergey V. Sennikov, Sergey V. Sennikov

    Published 2025-02-01
    “…Adoptive transfer of Tregs includes polyclonal Tregs with non-specific effects and antigen-specific Tregs in the form of CAR-Treg and TCR-Treg. …”
    Get full text
    Article
  17. 517

    Immune Reactions Against Elongation Factor 2 Kinase: Specific Pathogenesis of Gastric Ulcer from Helicobacter pylori Infection by Kiyoshi Ayada, Kenji Yokota, Yoshiro Kawahara, Yumiko Yamamoto, Kazuyuki Hirai, Tomoki Inaba, Masahide Kita, Hiroyuki Okada, Kazuhide Yamamoto, Keiji Oguma

    Published 2009-01-01
    “…This antigen was over-expressed by a stressful (heat-stressed) environment, and was identified as elongation factor 2 kinase (EF-2K) by western blotting. …”
    Get full text
    Article
  18. 518

    Optimizing Microneutralization and IFN-γ ELISPOT Assays to Evaluate Mpox Immunity by Yinyi Yu, Krystal Meza, Chase Colbert, Daniel F. Hoft, Anna Jaunarajs, Azra Blazevic, Sharon E. Frey, Getahun Abate

    Published 2024-12-01
    “…In addition, assays to measure T cell responses require the use of specific antigens, which may not be the same for all pox viruses. …”
    Get full text
    Article
  19. 519

    Association of Haemostatic and Inflammatory Biomarkers with Nephropathy in Type 1 Diabetes Mellitus by Caroline Pereira Domingueti, Rodrigo Bastos Fóscolo, Janice Sepúlveda Reis, Fernanda Magalhães Freire Campos, Luci Maria S. Dusse, Maria das Graças Carvalho, Karina Braga Gomes, Ana Paula Fernandes

    Published 2016-01-01
    “…Elevated levels of INF-γ, VWF, ADAMTS13 antigen, D-Dimer, and reduced ADAMTS13 activity/antigen ratio were observed in patients with nephropathy as compared to those without nephropathy (P=0.001, P<0.001, P<0.001, P<0.001, and P<0.001, resp.). …”
    Get full text
    Article
  20. 520

    Construction of a prognostic prediction model for colorectal cancer based on 5-year clinical follow-up data by Boao Xiao, Min Yang, Yao Meng, Weimin Wang, Yuan Chen, Chenglong Yu, Longlong Bai, Lishun Xiao, Yansu Chen

    Published 2025-01-01
    “…SHAP analysis revealed that increased perioperative transfusion quantity, higher tumor AJCC stage, elevated carcinoembryonic antigen level, elevated carbohydrate antigen 19–9 (CA19-9) level, advanced age, and elevated carbohydrate antigen 125 (CA125) level were correlated with increased individual mortality risk. …”
    Get full text
    Article